Effect of botulinum toxin type a on a rat surgical wound model

Clinical and Experimental Otorhinolaryngology

Volumn 2, Issue 1, 2009, Pages 20-27

  Lee, Byung Joo ^a   Jeong, Jae Hwi ^b   Wang, Soo Geun ^c   Lee, Jin Choon ^a   Goh, Eui Kyung ^a,b   Kim, Hwal Woong ^a  

^a Departments of Otorhinolaryngology Head and Neck Surgery   (South Korea)

^b Pusan National University School of Medicine   (South Korea)

^c Pusan National University   (South Korea)

Author keywords

Botulinum toxin type A; Fibrosis; Wound healing

Indexed keywords

EID: 68249112119     PISSN: 19768710     EISSN: 20050720     Source Type: Journal    
DOI: 10.3342/ceo.2009.2.1.20     Document Type: Article

References (21)

1. Manuskialti W., Fitzpatrick RE. Treatment response of keloidal and hypertrophic sternotomy scars: comparison among intralesional corticosteroid, 5-fluorouracil, and 585-nm flashlamp-pumped pulsed-dye laser treatments. Arch Dermatol. 2002 Sep;138(9):1149-55.
2. Fitzpatrick RE. Treatment of inflamed hypertrophic scars using intralesional 5-FU. Dermatol Surg. 1999 Mar;25(3):224-32.
3. Chowdri NA, Masarat M., Mattoo A., Darzi MA. Keloids and hypertrophic scars: results with intraoperative and serial postoperative corticosteroid injection therapy. Aust N Z J Surg. 1999 Sep;69(9):655-9.
4. Alster T. Laser scar revision: comparison study of 585-nm pulsed dye laser with and without intralesional corticosteroids. Dermatol Surg. 2003 Jan;29 (1):25-9.
5. Crooke ST, Bradner WT. Mitomycin C: a review. Cancer Treat Rev. 1976 Sep;3(3):121-39.
6. Miyamura S., Shigeno N., Matsui M., Wakaki S., Uzu K. The biological studies on mitomycin I: antibacterial activities of mitomycin derivatives. J Antibiot (Tokyo). 1967 Mar;20(2):72-6.
7. Hu D., Sires BS, Tong DC, Royack GA, Oda D. Effect of brief exposure to mitomycin C on cultured human nasal mucosa fibroblasts. Ophthal Plast Reconstr Surg. 2000 Mar;16(2):119-25.
8. Garrett CG, Soto J., Riddick J., Billante CR, Reinisch L. Effect of mitomycin-C on vocal fold healing in a canine model. Ann Otol Rhinol Laryngol. 2001 Jan;110 (1):25-30.
9. De Bruijn EA, Sleeboom HP, van Helsdingen PJ, van Oosterom AT, Tjaden UR, Maes RA. Pharmacodynamics and pharmacokinetics of intravesical mitomycin C upon different dwelling times. Int J Cancer. 1992 May 28;51(3):359-64.
10. Oboshi S., Matsui M., Ishii S., Masago N., Wakaki S. Antitumor studies on mitomycin derivatives. II. Effec of solid tumor of sarcoma-180. Gann. 1967 Aug;58(4):315-21.
11. Hueman EM, Simpson CB. Airway complications from topical mitomycin C. Otolaryngol Head Neck Surg. 2005 Dec;133(6):831-5.
12. Sherris DA, Larrabee WF Jr, Murakami CS. Management of scar contractures, hypertrophic scars, and keloids. Otolaryngol Clin North Am. 1995 Oct;28(5):1057-68.
13. Blitzer A., Sulica L. Botulinum toxin: basic science and clinical uses in otolaryngology. Laryngoscope. 2001 Feb;111(2):218-26.
14. Keir J. Botulinum toxin-physiology and applications in head and neck disorders. Head Neck. 2005 Jun;27(6):525-35.
15. Gassner HG, Sherris DA. Chemoimmobilization: improving predictability in the treatment of facial scars. Plast Reconstr Surg. 2003 Oct;112(5): 1464-6.
16. Kantor J., Margolis DJ. Efficacy and prognostic value of simple wound measurements. Arch Dermatol. 1998 Dec;134(12):1571-4.
17. Philips LG. Wound healing. In: Townsend CM, Beauchamp RD, Evers BM, Mattox KL, editors. Textbook of surgery. 16th ed. Philadelphia (PA): WB Saunders Co.: 2001. p. 131-55.
18. Ribeiro Fde A., Guaraldo L., Borges Jde P., Zacchi FF, Eckley CA. Clinical and histological healing of surgical wounds treated with mitomycin C. Laryngoscope. 2004 Jan;114 (1):148-52.
19. Gassner HG, Sherris DA, Otley CC. Treatment of facial wounds with botulinum toxin A improves cosmetic outcome in primates. Plast Reconstr Surg. 2000 May;105(6):1948-53.
20. Gassner HG, Brissett AE, Otley CC, Boahene DK, Boggust AJ, Weaver AL, et al. Botulinum toxin to improve facial wound healing: a prospective, blinded, placebo-controlled study. Mayo Clin Proc. 2006 Aug;81(8):1023-8.
21. Khera M., Boone TB, Smith CP. Botulinum toxin type A: a novel approach to the treatment of recurrent urethral strictures. J Urol. 2004 Aug; 172(2):574-5.