-
1
-
-
0016713286
-
Rapamycin (AY-22,989), a new antifungal antibiotic. II. Fermentation, isolation and characterization
-
Sehgal SN, Baker H, Vézina C. Rapamycin (AY-22,989), a new antifungal antibiotic. II. Fermentation, isolation and characterization. J Antibiot (Tokyo). 1975;28(10):727-32.
-
(1975)
J Antibiot (Tokyo)
, vol.28
, Issue.10
, pp. 727-732
-
-
Sehgal, S.N.1
Baker, H.2
Vézina, C.3
-
2
-
-
0038282474
-
The evolving role of sirolimus in renal transplantation
-
Dupont P, Warrens AN. The evolving role of sirolimus in renal transplantation. QJM. 2003;96(6):401-9.
-
(2003)
QJM
, vol.96
, Issue.6
, pp. 401-409
-
-
Dupont, P.1
Warrens, A.N.2
-
3
-
-
0141765805
-
SIRIUS Investigators. Sirolimus-eluting stents versus standard stents in patients with stenosis in a native coronary artery
-
Moses JW, Leon MB, Popma JJ, Fitzgerald PJ, Holmes DR, O'Shaughnessy C, Caputo RP, Kereiakes DJ, Williams DO, Teirstein PS, Jaeger JL, Kuntz RE; SIRIUS Investigators. Sirolimus-eluting stents versus standard stents in patients with stenosis in a native coronary artery. N Engl J Med. 2003; 349(14):1315-23.
-
(2003)
N Engl J Med
, vol.349
, Issue.14
, pp. 1315-1323
-
-
Moses, J.W.1
Leon, M.B.2
Popma, J.J.3
Fitzgerald, P.J.4
Holmes, D.R.5
O'Shaughnessy, C.6
Caputo, R.P.7
Kereiakes, D.J.8
Williams, D.O.9
Teirstein, P.S.10
Jaeger, J.L.11
Kuntz, R.E.12
-
4
-
-
0141542640
-
-
Comment, in
-
Comment in: N Engl J Med. 2003;349(14):1307-9.
-
(2003)
N Engl J Med
, vol.349
, Issue.14
, pp. 1307-1309
-
-
-
5
-
-
0345872077
-
-
author reply 413-4
-
N Engl J Med. 2004;350(4):413-4; author reply 413-4.
-
(2004)
N Engl J Med.
, vol.350
, Issue.4
, pp. 413-414
-
-
-
6
-
-
0345872077
-
-
author reply 413-4
-
N Engl J Med. 2004;350(4): 413-4; author reply 413-4.
-
(2004)
N Engl J Med
, vol.350
, Issue.4
, pp. 413-414
-
-
-
7
-
-
0027301130
-
Rapamycin inhibits arterial intimal thickening caused by both alloimmune and mechanical injury. Its effect on cellular, growth factor, and cytokine response in injured vessels
-
Gregory CR, Huie P, Billingham ME, Morris LE. Rapamycin inhibits arterial intimal thickening caused by both alloimmune and mechanical injury. Its effect on cellular, growth factor, and cytokine response in injured vessels. Transplantation. 1993;55(6):1409-18.
-
(1993)
Transplantation
, vol.55
, Issue.6
, pp. 1409-1418
-
-
Gregory, C.R.1
Huie, P.2
Billingham, M.E.3
Morris, L.E.4
-
8
-
-
0032105481
-
Rapamune (RAPA, rapamycin, sirolimus): mechanism of action immunosuppressive effect results from blockade of signal transduction and inhibition of cell cycle progression
-
Sehgal SN. Rapamune (RAPA, rapamycin, sirolimus): mechanism of action immunosuppressive effect results from blockade of signal transduction and inhibition of cell cycle progression. Clin Biochem. 1998;31(5):335-40.
-
(1998)
Clin Biochem
, vol.31
, Issue.5
, pp. 335-340
-
-
Sehgal, S.N.1
-
9
-
-
70449415044
-
-
Republished in: Clin Biochem
-
Republished in: Clin Biochem. 2006;39(5):484-9.
-
(2006)
, vol.39
, Issue.5
, pp. 484-489
-
-
-
10
-
-
2342559981
-
The TOR pathway: a target for cancer therapy
-
Bjornsti MA, Houghton PJ. The TOR pathway: a target for cancer therapy. Nat Rev Cancer. 2004;4(5):335-48.
-
(2004)
Nat Rev Cancer
, vol.4
, Issue.5
, pp. 335-348
-
-
Bjornsti, M.A.1
Houghton, P.J.2
-
11
-
-
20444459116
-
Antitumor activity of rapamycin in a transgenic mouse model of ErbB2-dependent human breast cancer
-
Liu M, Howes A, Lesperance J, Stallcup WB, Hauser CA, Kadoya K, et al. Antitumor activity of rapamycin in a transgenic mouse model of ErbB2-dependent human breast cancer. Cancer Res. 2005;65(12):5325-36.
-
(2005)
Cancer Res
, vol.65
, Issue.12
, pp. 5325-5336
-
-
Liu, M.1
Howes, A.2
Lesperance, J.3
Stallcup, W.B.4
Hauser, C.A.5
Kadoya, K.6
-
12
-
-
0036174289
-
Rapamycin inhibits primary and metastatic tumor growth by antiangiogenesis: involvement of vascular endothelial growth factor
-
Guba M, von Breitenbuch P, Steinbauer M, Koehl G, Flegel S, Hornung M, et al. Rapamycin inhibits primary and metastatic tumor growth by antiangiogenesis: involvement of vascular endothelial growth factor. Nat Med. 2002; 8(2):128-35.
-
(2002)
Nat Med
, vol.8
, Issue.2
, pp. 128-135
-
-
Guba, M.1
von Breitenbuch, P.2
Steinbauer, M.3
Koehl, G.4
Flegel, S.5
Hornung, M.6
-
13
-
-
12244267962
-
-
Comment in
-
Comment in: Kidney Int. 2003;63(3):1160-1.
-
(2003)
Kidney Int
, vol.63
, Issue.3
, pp. 1160-1161
-
-
-
14
-
-
0028144044
-
Rapamycin inhibits corneal allograft rejection and neovascularization
-
Olsen TW, Benegas NM, Joplin AC, Evangelista T, Mindrup EA, Holland EJ. Rapamycin inhibits corneal allograft rejection and neovascularization. Arch Ophthalmol. 1994;112(11):1471-5.
-
(1994)
Arch Ophthalmol
, vol.112
, Issue.11
, pp. 1471-1475
-
-
Olsen, T.W.1
Benegas, N.M.2
Joplin, A.C.3
Evangelista, T.4
Mindrup, E.A.5
Holland, E.J.6
-
15
-
-
0028951185
-
-
Erratum in
-
Erratum in: Arch Ophthalmol 1995; 113(2):144.
-
(1995)
Arch Ophthalmol
, vol.113
, Issue.2
, pp. 144
-
-
-
16
-
-
25444435486
-
Systemic rapamycin inhibits retinal and choroidal neovascularization in mice
-
Dejneka NS, Kuroki AM, Fosnot J, Tang W, Tolentino MJ, Bennett J. Systemic rapamycin inhibits retinal and choroidal neovascularization in mice. Mol Vis. 2004;10:964-72.
-
(2004)
Mol Vis
, vol.10
, pp. 964-972
-
-
Dejneka, N.S.1
Kuroki, A.M.2
Fosnot, J.3
Tang, W.4
Tolentino, M.J.5
Bennett, J.6
-
17
-
-
0031423936
-
Tacrolimus-rapamycin combination therapy for experimental autoimmune uveoretinitis
-
Ikeda E, Hikita N, Eto K, Moshisuki M. Tacrolimus-rapamycin combination therapy for experimental autoimmune uveoretinitis. Jpn J Ophthalmol. 1997; 41(6):396-402.
-
(1997)
Jpn J Ophthalmol
, vol.41
, Issue.6
, pp. 396-402
-
-
Ikeda, E.1
Hikita, N.2
Eto, K.3
Moshisuki, M.4
-
18
-
-
0028858836
-
Synergistic effect of rapamycin and cyclosporin A in the treatment of experimental autoimmune uveoretinitis
-
Martin DF, DeBarge LR, Nussenblatt RB, Chan CC, Roberge FG. Synergistic effect of rapamycin and cyclosporin A in the treatment of experimental autoimmune uveoretinitis. J Immunol. 1995;154(2):922-7.
-
(1995)
J Immunol
, vol.154
, Issue.2
, pp. 922-927
-
-
Martin, D.F.1
DeBarge, L.R.2
Nussenblatt, R.B.3
Chan, C.C.4
Roberge, F.G.5
-
19
-
-
20344366299
-
The efficacy of sirolimus in the treatment of patients with refractory uveitis
-
Shanmuganathan VA, Casely EM, Raj D, Powell RJ, Joseph A, Amoaku WM, Dua HS. The efficacy of sirolimus in the treatment of patients with refractory uveitis. Br J Ophthalmol. 2005;89(6):666-9.
-
(2005)
Br J Ophthalmol
, vol.89
, Issue.6
, pp. 666-669
-
-
Shanmuganathan, V.A.1
Casely, E.M.2
Raj, D.3
Powell, R.J.4
Joseph, A.5
Amoaku, W.M.6
Dua, H.S.7
-
20
-
-
0036906021
-
Effect of body temperature on electroretinogram of mice
-
Mizota A, Adachi-Usami E. Effect of body temperature on electroretinogram of mice. Invest Ophthalmol Vis Sci. 2002;43(12):3754-7.
-
(2002)
Invest Ophthalmol Vis Sci
, vol.43
, Issue.12
, pp. 3754-3757
-
-
Mizota, A.1
Adachi-Usami, E.2
-
21
-
-
0030070386
-
The effect of in vivo retinal cooling on the electroretinogram of the rabbit
-
Lachapelle P, Benoit J, Guité P. The effect of in vivo retinal cooling on the electroretinogram of the rabbit. Vision Res. 1996;36(3):339-44.
-
(1996)
Vision Res
, vol.36
, Issue.3
, pp. 339-344
-
-
Lachapelle, P.1
Benoit, J.2
Guité, P.3
-
22
-
-
0036782278
-
VEGF and the quest for tumour angiogenesis factors
-
Ferrara N. VEGF and the quest for tumour angiogenesis factors. Nat Rev Cancer. 2002;2(10):795-803.
-
(2002)
Nat Rev Cancer
, vol.2
, Issue.10
, pp. 795-803
-
-
Ferrara, N.1
-
23
-
-
0024818355
-
Vascular endothelial growth factor is a secreted angiogenic mitogen
-
Leung DW, Cachianes G, Kuang WJ, Goeddel DV, Ferrara N. Vascular endothelial growth factor is a secreted angiogenic mitogen. Science. 1989; 246(4935):1306-9.
-
(1989)
Science
, vol.246
, Issue.4935
, pp. 1306-1309
-
-
Leung, D.W.1
Cachianes, G.2
Kuang, W.J.3
Goeddel, D.V.4
Ferrara, N.5
-
24
-
-
0029831672
-
Subfoveal fibrovascular membranes in age-related macular degeneration express vascular endothelial growth factor
-
Kvanta A, Algvere PV, Berglin L, Seregard S. Subfoveal fibrovascular membranes in age-related macular degeneration express vascular endothelial growth factor. Invest Ophthalmol Vis Sci. 1996;37(9):1929-34.
-
(1996)
Invest Ophthalmol Vis Sci
, vol.37
, Issue.9
, pp. 1929-1934
-
-
Kvanta, A.1
Algvere, P.V.2
Berglin, L.3
Seregard, S.4
-
25
-
-
11144239923
-
VEGF Inhibition Study in Ocular Neovascularization Clinical Trial Group. Pegaptanib for neovascular age-related macular degeneration
-
Gragoudas ES, Adamis AP, Cunningham ET Jr, Feinsod M, Guyer DR; VEGF Inhibition Study in Ocular Neovascularization Clinical Trial Group. Pegaptanib for neovascular age-related macular degeneration. N Engl J Med. 2004;351(27):2805-16.
-
(2004)
N Engl J Med
, vol.351
, Issue.27
, pp. 2805-2816
-
-
Gragoudas, E.S.1
Adamis, A.P.2
Cunningham E.T., Jr.3
Feinsod, M.4
Guyer, D.R.5
-
26
-
-
70449456706
-
-
Comment in
-
Comment in: ACP J Club. 2005;143(1):18.
-
(2005)
ACP J Club
, vol.143
, Issue.1
, pp. 18
-
-
-
27
-
-
11144230020
-
-
N Engl J Med. 2004;351(27):2863-5.
-
(2004)
N Engl J Med.
, vol.351
, Issue.27
, pp. 2863-2865
-
-
-
28
-
-
17244378434
-
-
author reply 1720-1
-
N Engl J Med. 2005;352(16):1720-1; author reply 1720-1.
-
(2005)
N Engl J Med.
, vol.352
, Issue.16
, pp. 1720-1721
-
-
-
29
-
-
33646948521
-
Pegaptanib sodium for neovascular age-related macular degeneration: two-year safety results of the two prospective, multicenter, controlled clinical trials
-
VEGF Inhibition Study in Ocular Neovascularization (V.I.S.I.O.N.) Clinical Trial Group
-
VEGF Inhibition Study in Ocular Neovascularization (V.I.S.I.O.N.) Clinical Trial Group, D'Amico DJ, Masonson HN, Patel M, Adamis AP, Cunningham ET Jr, Guyer DR, Katz B. Pegaptanib sodium for neovascular age-related macular degeneration: two-year safety results of the two prospective, multicenter, controlled clinical trials. Opthalmology. 2006;113(6): 992-1001.e6.
-
(2006)
Opthalmology
, vol.113
, Issue.6
, pp. 992
-
-
D'Amico, D.J.1
Masonson, H.N.2
Patel, M.3
Adamis, A.P.4
Cunningham E.T., Jr.5
Guyer, D.R.6
Katz, B.7
-
30
-
-
20444402687
-
Ranibizumab therapy for neovascular age related macular degeneration
-
Michels S, Rosenfeld PJ. Ranibizumab therapy for neovascular age related macular degeneration. Retinal Physician. 2004;1(1):16-22.
-
(2004)
Retinal Physician
, vol.1
, Issue.1
, pp. 16-22
-
-
Michels, S.1
Rosenfeld, P.J.2
-
31
-
-
33645331188
-
Tolerability and efficacy of multiple escalating doses of ranibizumab (Lucentis) for neovascular age-related macular degeneration
-
Rosenfeld PJ, Heier JS, Hantsbarger G, Shams N. Tolerability and efficacy of multiple escalating doses of ranibizumab (Lucentis) for neovascular age-related macular degeneration. Ophthalmology. 2006;113(4):623.e1.
-
(2006)
Ophthalmology
, vol.113
, Issue.4
-
-
Rosenfeld, P.J.1
Heier, J.S.2
Hantsbarger, G.3
Shams, N.4
-
32
-
-
33644502828
-
Intravitreal bevacizumab (Avastin) for neovascular age-related macular degeneration
-
e5
-
Avery RL, Pieramici DJ, Rabena MD, Castellarin AA, Nasir MA, Giust MJ. Intravitreal bevacizumab (Avastin) for neovascular age-related macular degeneration. Ophthalmology. 2006;113(3):363-72.e5.
-
(2006)
Ophthalmology
, vol.113
, Issue.3
, pp. 363-372
-
-
Avery, R.L.1
Pieramici, D.J.2
Rabena, M.D.3
Castellarin, A.A.4
Nasir, M.A.5
Giust, M.J.6
-
33
-
-
0036789574
-
Regulation of hypoxia-inducible factor 1alpha expression and function by the mammalian target of rapamycin
-
Hudson CC, Liu M, Chiang GG, Otterness DM, Loomis DC, Kaper F, et al. Regulation of hypoxia-inducible factor 1alpha expression and function by the mammalian target of rapamycin. Mol Cell Biol. 2002;22(20):7004-14.
-
(2002)
Mol Cell Biol
, vol.22
, Issue.20
, pp. 7004-7014
-
-
Hudson, C.C.1
Liu, M.2
Chiang, G.G.3
Otterness, D.M.4
Loomis, D.C.5
Kaper, F.6
-
34
-
-
0030751493
-
Differential transcriptional regulation of the two vascular endothelial growth factor receptor genes. Flt-1, but not Flk-1/KDR, is up-regulated by hypoxia
-
Gerber HP, Condorelli F, Park J, Ferrara N. Differential transcriptional regulation of the two vascular endothelial growth factor receptor genes. Flt-1, but not Flk-1/KDR, is up-regulated by hypoxia. J Biol Chem. 1997;272(38): 23659-67.
-
(1997)
J Biol Chem
, vol.272
, Issue.38
, pp. 23659-23667
-
-
Gerber, H.P.1
Condorelli, F.2
Park, J.3
Ferrara, N.4
-
35
-
-
0036275356
-
Hypoxia enhances vascular cell proliferation and angiogenesis in vitro via rapamycin (mTOR)-dependent signaling
-
Erratum in: FASEB J. 20 9 1573. 2006
-
Humar R, Kiefer FN, Berns H, Resink TJ, Battegay EJ. Hypoxia enhances vascular cell proliferation and angiogenesis in vitro via rapamycin (mTOR)-dependent signaling. FASEB J. 2002;16(8):771-80. Erratum in: FASEB J. 2006;20(9):1573.
-
(2002)
FASEB J
, vol.16
, Issue.8
, pp. 771-780
-
-
Humar, R.1
Kiefer, F.N.2
Berns, H.3
Resink, T.J.4
Battegay, E.J.5
-
36
-
-
0037008770
-
Insulin stimulates hypoxia-inducible factor 1 through a phosphatidylinositol 3-kinase/target of rapamycin-dependent signaling pathway
-
Treins C, Giorgetti-Peraldi S, Murdaca J, Semenza GL, Van Obberghen E. Insulin stimulates hypoxia-inducible factor 1 through a phosphatidylinositol 3-kinase/target of rapamycin-dependent signaling pathway. J Biol Chem. 2002;277(31):27975-81.
-
(2002)
J Biol Chem
, vol.277
, Issue.31
, pp. 27975-27981
-
-
Treins, C.1
Giorgetti-Peraldi, S.2
Murdaca, J.3
Semenza, G.L.4
Van Obberghen, E.5
|