Differential translocation of nuclear factor-kappaB in a cardiac muscle cell line under gravitational changes

Journal of Biomechanical Engineering

Volumn 131, Issue 6, 2009, Pages

  Kwon, Ohwon ^a   Tranter, Michael ^b   Jones, W Keith ^b   Sankovic, John M ^c   Banerjee, Rupak K ^a  

^a University of Cincinnati   (United States)

^b UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^c NASA GLENN RESEARCH CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTIVE RESPONSE; CARDIAC CELL; CARDIAC MUSCLES; CELL TYPES; DYNAMIC CONTROLS; ENZYME LINKED IMMUNOSORBENT ASSAY; G-CONDITION; MOLECULAR SIGNALING; MUSCLE ATROPHY; NUCLEAR FACTOR KAPPAB; NUCLEAR FACTORS; NUCLEAR TRANSLOCATIONS; REGULATORY PATHWAY; ROTATING WALL VESSEL BIOREACTORS; SIMULATED MICROGRAVITY; TRANSCRIPTIONAL NETWORKS; WESTERN BLOTS; WESTERN BLOTTING;

CELL CULTURE; MICROGRAVITY; MICROGRAVITY PROCESSING; MUSCLE; PHYSIOLOGICAL MODELS; TRANSCRIPTION FACTORS;

TRANSCRIPTION;

I KAPPA B; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ARTICLE; DNA BINDING; ENZYME LINKED IMMUNOSORBENT ASSAY; HEART MUSCLE CELL; NONHUMAN; RAT; WESTERN BLOTTING; ANIMAL; CELL LINE; CELL NUCLEUS; GRAVITY; HUMAN; METABOLISM; PHYSIOLOGY; PROTEIN TRANSPORT;

RATTUS;

ANIMALS; CELL LINE; CELL NUCLEUS; GRAVITATION; HUMANS; MYOCYTES, CARDIAC; PROTEIN TRANSPORT; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR-ALPHA;

EID: 68149168705     PISSN: 01480731     EISSN: 15288951     Source Type: Journal    
DOI: 10.1115/1.3128718     Document Type: Article

References (24)

1. Hughes-Fulford, M., 1991, "Altered Cell Function in Microgravity," Exp. Gerontol., 26, pp. 247-256.
2. Nicogossian, A. E., Huntoon, C. L., and Pool, S. L., 1989, Space Physiology and Medicine, Lea and Febiger, Malvern, PA.
3. Schwarz, R. P., Goodwin, T. J., and Wolf, D. A., 1992, "Cell Culture for Three-Dimensional Modeling in Rotating Wall Vessels: An Application of Simulated Microgravity," J. Tissue Cult. Methods, 14, pp. 51-57.
4. Freed, L. E., and Vunjak-Novakovic, G., 1997, "Microgravity Tissue Engineering," In Vitro Cell. Dev. Biol.: Anim., 33, pp. 381-385.
5. Hammond, T. G., and Hammond, J. M., 2001, "Optimized Suspension Culture: The Rotating-Wall Vessel," Am. J. Physiol. Renal Physiol., 281, pp. F12-25.
6. Kwon, O., Sartor, M., Tomlinson, C. R., Millard, R. W., Olah, M. E., Sankovic, J. M., and Banerjee, R. K., 2006, "Effect of Simulated Microgravity on Oxidation-Sensitive Gene Expression in PC12 Cells," Adv. Space Res., 38, pp. 1168-1176.
7. Schena, M., Shalon, D., Heller, R., Chai, A., Brown, P. O., and Davis, R. W., 1996, "Parallel Human Genome Analysis: Microarray-Based Expression Monitoring of 1000 Genes," Proc. Natl. Acad. Sci. U.S.A., 93, pp. 10614-10619.
8. Asyali, M. H., Shoukri, M. M., Demirkaya, O., and Khabar, K. S., 2004, "Assessment of Reliability of Microarray Data and Estimation of Signal Thresholds Using Mixture Modeling," Nucleic Acids Res., 32, pp. 2323-2335.
9. Xia, Q., Hendrickson, E. L., Zhang, Y., Wang, T., Taub, F., Moore, B. C., Porat, I., Whitman, W. B., Hackett, M., and Leigh, J. A., 2006, "Quantitative Proteomics of the Archaeon Methanococcus Maripaludis Validated by Microarray Analysis and Real Time PCR," Mol. Cell Proteomics, 5, pp. 868-881.
10. Jones, W. K., Brown, M., Wilhide, M., He, S., and Ren, X., 2005, "NF-κB in Cardiovascular Disease," Cardiovasc. Toxicol., 5, pp. 183-201.
11. Hayden, M. S., and Ghosh, S., 2004, "Signaling to NF-κB," Genes Dev., 18, pp. 2195-2224.
12. Mercurio, F., and Manning, A. M., 1999, "NF-κB as a Primary Regulator of the Stress Response," Oncogene, 18, pp. 6163-6171.
13. Kramer, H. F., and Goodyear, L. J., 2007, "Exercise, MAPK, and NF-κB Signaling in Skeletal Muscle," J. Appl. Physiol., 103, pp. 388-395.
14. Kimes, B. W., and Brandt, B. L., 1976, "Properties of a Clonal Muscle Cell Line From Rat Heart," Exp. Cell Res., 98, pp. 367-381.
15. Pagano, M., Naviglio, S., Spina, A., Chiosi, E., Castoria, G., Romano, M., Sorrentino, A., Illiano, F., and Illiano, G., 2004, "Differentiation of H9c2 Cardiomyoblasts: The Role of Adenylate Cyclase System," J. Cell. Physiol., 198, pp. 408-416.
16. Williams, D. R., 2003, "The Biomedical Challenges of Space Flight," Annu. Rev. Med., 54, pp. 245-256.
17. Kwon, O., Devarakonda, S., Sankovic, J. M., and Banerjee, R. K., 2008, "Oxygen Transport and Consumption by Suspended Cells in Microgravity: A Multiphase Analysis," Biotechnol. Bioeng., 99, pp. 99-107.
18. Brown, M., McGuinness, M., Wright, T., Ren, X., Wang, Y., Boivin, G. P., Hahn, H., Feldman, A. M., and Jones, W. K., 2005, "Cardiac-Specific Blockade of NF-κB in Cardiac Pathophysiology: Differences Between Acute and Chronic Stimuli In Vivo," Am. J. Physiol. Heart Circ. Physiol., 289, pp. H466-476.
19. Guo, M., Sahni, S. K., Sahni, A., and Francis, C. W., 2004, "Fibrinogen Regulates the Expression of Inflammatory Chemokines Through NF-kappaB Activation of Endothelial Cells," Thromb. Haemostasis, 92, pp. 858-866. (Pubitemid 39386712)
20. Hammar, E. B., Irminger, J. C., Rickenbach, K., Parnaud, G., Ribaux, P., Bosco, D., Rouiller, D. G., and Halban, P. A., 2005, "Activation of NF-κB by Extracellular Matrix is Involved in Spreading and Glucose-Stimulated Insulin Secretion of Pancreatic Beta Cells," J. Biol. Chem., 280, pp. 30630-30637.
21. Aubert, A. E., Beckers, F., and Verheyden, B., 2005, "Cardiovascular Function and Basics of Physiology in Microgravity," Acta Cardiol., 60, pp. 129-151. (Pubitemid 40835427)
22. Jones, W. K., Grupp, I. L., Doetschman, T., Grupp, G., Osinska, H., Hewett, T. E., Boivin, G., Gulick, J., Ng, W. A., and Robbins, J., 1996, "Ablation of the Murine Alpha Myosin Heavy Chain Gene Leads to Dosage Effects and Functional Deficits in the Heart," J. Clin. Invest., 98, pp. 1906-1917.
23. Carlsson, S. I., Bertilaccio, M. T., Ballabio, E., and Maier, J. A., 2003, "Endothelial Stress by Gravitational Unloading: Effects on Cell Growth and Cytoskeletal Organization," Biochim. Biophys. Acta, 1642, pp. 173-179.
24. Wang, E., 1999, "Age-Dependent Atrophy and Microgravity Travel: What Do They Have in Common?" FASEB J., 13, pp. 167-174.