Characterization of the contents of ascending colon to which drugs are exposed after oral administration to healthy adults

Pharmaceutical Research

Volumn 26, Issue 9, 2009, Pages 2141-2151

  Diakidou, Amalia ^a   Vertzoni, Maria ^a   Goumas, Konstantinos ^b   Söderlind, Erik ^c   Abrahamsson, Bertil ^c   Dressman, Jennifer ^d   Reppas, Christos ^a  

^a UNIVERSITY OF ATHENS   (Greece)

^b RED CROSS HOSPITAL   (Greece)

^c ASTRAZENECA R AND D   (Sweden)

^d GOETHE UNIVERSITY   (Germany)

Author keywords

Ascending colon; Charged aerosol detector (CAD); Fasted state; Fed state; Lumenal composition

Indexed keywords

ACETIC ACID; BISACODYL; BUFFER; BUTYRIC ACID; CARBOHYDRATE; CHENODEOXYCHOLIC ACID; CHOLESTEROL; CHOLIC ACID; GOLYTELY; ISOBUTYRIC ACID; LONG CHAIN FATTY ACID; PHOSPHATIDYLCHOLINE; PROTEIN; WATER;

ADULT; ARTICLE; ASCENDING COLON; CARBOHYDRATE ANALYSIS; COLON ABSORPTION; COLONOSCOPY; CONTROLLED STUDY; DIET RESTRICTION; DRUG DELIVERY SYSTEM; DRUG EXPOSURE; FEEDING; FEMALE; FLUID INTAKE; HUMAN; HUMAN EXPERIMENT; IN VITRO STUDY; INTESTINE PARAMETERS; MALE; MEAL; NORMAL HUMAN; OSMOLALITY; PH; PRIORITY JOURNAL; PROTEIN CONTENT; SUPERNATANT; SURFACE TENSION; ULTRACENTRIFUGATION; WATER CONTENT;

ADMINISTRATION, ORAL; ADULT; COLON, ASCENDING; CROSS-OVER STUDIES; HUMANS; HYDROGEN-ION CONCENTRATION; PHARMACOLOGY; PILOT PROJECTS; REFERENCE VALUES;

EID: 68149165782     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-009-9927-x     Document Type: Article

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