Effect of kolaviron, a biflavonoid complex from garcinia kola seeds, on ethanol-induced oxidative stress in liver of adult wistar rats

Journal of Medicinal Food

Volumn 12, Issue 3, 2009, Pages 584-590

  Adaramoye, O A ^a   Awogbindin, I ^a   Okusaga, J O ^a  

^a UNIVERSITY OF IBADAN   (Nigeria)

Author keywords

Ethanol; Garcinia kola; Kolaviron; Liver; Oxidative stress; Rat

Indexed keywords

ALANINE AMINOTRANSFERASE; ALCOHOL; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; CATALASE; GLUTATHIONE; GLUTATHIONE TRANSFERASE; KOLAVIRON; MALONALDEHYDE; SUPEROXIDE DISMUTASE;

ALCOHOL LIVER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; GARCINIA KOLA; LIPID PEROXIDATION; LIVER; LIVER TOXICITY; MALE; NONHUMAN; OXIDATIVE STRESS; PLANT SEED; PRIORITY JOURNAL; RAT;

ANIMALS; ANTIOXIDANTS; ETHANOL; FLAVONOIDS; GARCINIA KOLA; GLUTATHIONE TRANSFERASE; HEPATITIS, ALCOHOLIC; LIPID PEROXIDATION; LIVER; MALE; OXIDATIVE STRESS; PHYTOTHERAPY; PLANT EXTRACTS; RANDOM ALLOCATION; RATS; RATS, WISTAR; SEEDS; SUPEROXIDE DISMUTASE;

ANIMALIA; GARCINIA KOLA; RATTUS; RATTUS NORVEGICUS;

EID: 68149162144     PISSN: 1096620X     EISSN: None     Source Type: Journal    
DOI: 10.1089/jmf.2008.0138     Document Type: Article

References (42)

1. Lieber CS: Alcohol and the liver: metabolism of alcohol and its role in hepatic and extrahepatic diseases. Mt Sinai J Med 2000;67:84-94.
2. Castilla R, Gonzalez R, Fouad D, Fraga E, Muntane J: Dual effect of ethanol on cell death in primary culture of human and rat hepatocytes. Alcohol Alcohol 2004;39:290-296.
3. Rintala J, Jaatinen P, Parkkila S, Sarviharju M, Kiianmaa K, Hervonen A, Niemelä O: Evidence of acetaldehyde-protein ad- duct formation in rat brain after lifelong consumption of ethanol. Alcohol Alcohol 2000;35:458-163.
4. Ozaras R, Tahan V, Aydin S, Uzun H, Kaya S, Senturk H: N- Acetylcysteine attenuates alcohol-induced oxidative stress in the rat. World J Gastroenterol 2003;9:125-128.
5. Koch O, Farre S, De Leo ME, Palozza P, Palazzotti B, Borrelo S, Palombini G, Cravero A, Galeotti T: Regulation of manganese superoxide dismutase (MnSOD) in chronic experimental alcoholism: effects of vitamin E-supplemented and-deficient diets. Alcohol Alcohol 2000;35:159-163.
6. Iwu MM, Igboko OA: Flavonoids of Garcinia kola seeds. J Nat Products 1982;45:650-651.
7. Cotterhill PJ, Scheinmann F, Stenhouse TA: Extractives from Guttiferae: kolaflavanone, a new biflavanone from the nuts of Garcinia kola Heckel. J Chem Soc Perkin Trans 1978;1:246-254.
8. Waterman PG, Hussain RA: Systematic significance of xan- thones, benzophenones and biflavonoids in Garcinia. Biochem SystEcol 1983;11:21-30.
9. Iwu MM, Igboko OA, Onwuchekwa U, Okunji CO: Evaluation of the anti-hepatotoxicity of the biflavonoids of Garcinia kola seeds. J Ethnopharmacol 1987;21:127-142.
10. Akintonwa A, Essien AR: Protective effects of Garcinia kola seed against paracetamol-induced hepatotoxicity in rats. J Eth-nopharmacol 1990;29:207-211.
11. Farombi EO, Adepoju BF, Ola-Davies OE, Emerole GO: Che- moprevention of aflatoxin B1-induced genotoxicity and hepatic oxidative damage in rats by kolaviron, a natural biflavonoid of Garcinia kola seeds. Eur J Cancer Prev 2005;14:207-214.
12. Adaramoye OA, Adeyemi EO: Hepatoprotection of D-galactosamine- induced toxicity in mice by purified fractions from Garcinia kola seed. Basic Clin Pharmacol Toxicol 2006;98:135-141.
13. Iwu MM, Igboko OA, Okunji CO, Tempesta MS: Anti-diabetic and aldose reductase activities of biflavanones of Garcinia kola. J Pharm Pharmacol 1990;42:290-292.
14. Adaramoye OA, Adeyemi EO: Hypoglycaemic and hypolipi- daemic effects of fractions from kolaviron, a biflavonoid complex from Garcinia kola in streptozotocin-induced diabetes mellitus rats. J Pharm Pharmacol 2006;8:121-128.
15. Adaramoye OA, Farombi EO, Adeyemi EO, Emerole GO: Inhibition of human low- density lipoprotein oxidation by flavonoids of Garcinia kola seeds. Pak J Med Sci 2005;21:331-339.
16. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ: Protein measurement with the Folin phenol reagent. J Biol Chem 1951; 193:265-275.
17. Mohun AF, Cook LJ: Simple method for measuring serum level of glutamate-oxaloacetate and glutamate-pyruvate transaminases in laboratories. J Clin Pathol 1957;10:394-399.
18. Reitman S, Frankel S: A colorimetric method for the determination of serum level of glutamate-oxaloacetate and pyruvate transaminases. Am J Clin Pathol 1957;28:56-63.
19. King EJ, Armstrong AR: Calcium, phosphorus and phosphatases. In: Practical Clinical Biochemistry. CBS Publishers, New Delhi, 1988, p. 458.
20. Walls R, Kumar KS, Hochstein P: Aging human erythrocytes. Differential sensitivity of young and old erythrocytes to hemo- lysis induced by peroxide in the presence of thyroxine. Arch Biochem Biophys 1976;176:463-168.
21. Moron MA, Depierre JW, Mannervick B: Levels of glutathione, glutathione reductase and glutathione-s-transferase activities in rat lung and liver. Biochim Biophys Acta 1979;582:67-78.
22. McCord JM, Fridovich I: Superoxide dismutase, an enzymatic function for erythrocuperin. J Biol Chem 1969;244:6049-6055.
23. Habig WH, Pabst MJ, Jakoby WB: Glutathione-S-transferases. The first enzymatic step in mercapturic acid formation. J Biol Chem 1974;249:7130-7139.
24. Aebi H: Catalase. In: Methods of Enzymatic Analysis (Bergmeyer HV, ed.). Verlag Chemie, New York, 1974, pp. 673-684.
25. Kasdallah-Grissa A, Mornagui B, Aouani E, Hammami M, Gharbi N, Kamoun A, El-Fazaa S: Protective effect of resveratrol on ethanol-induced lipid peroxidation in rats. Alcohol Alcohol 2006;41:236-239.
26. Kasdallah-Grissa A, Mornagui B, Aouani E, Hammami M, El May M, Gharbi N, Kamoun A, El-Fazaa S: Resveratrol, a red wine polyphenol, attenuates ethanol-induced oxidative stress in rat liver. Life Sci 2007;80:1033-1039.
27. Husain K, Mejia J, Lalla J, Kazim S: Dose response of alcohol- induced changes in BP, nitric oxide and antioxidants in rat plasma. Pharmacol Res 2005;51:337-343.
28. Jurczuk M, Brzoska MM, Moniuszko-Jakoniuk J, Galazyn- Sidorczuk M, Kulikowska-Karpḿska E: Antioxidant enzymes activity and lipid peroxidation in liver and kidney of rats exposed to cadmium and ethanol. Food Chem Toxicol 2004;42: 429-438.
29. Jurczuk M, Brzoska MM, Moniuszko-Jakoniuk J: Hepatic and renal concentrations of vitamins E and C in lead- and ethanol- exposed rats. An assessment of their involvement in the mechanisms of peroxidative damage. Food Chem Toxicol 2007;45: 1478-1486.
30. Devipriya N, Srinivasan M, Sudheer AR, Menon VP: Effect of ellagic acid, a natural polyphenol, on alcohol-induced pro- oxidant and antioxidant imbalance: a drug dose dependent study. Singapore Med J 2007;48:311-318.
31. Prakash P, Kumar PG, Laloroya M, Javeri T, Parihar MS: Super- oxide anion radical production as a cadmium mediated mechanism of toxicity in avian thyroid: an electron spin resonance study by spin trapping. Comp Biochem Physiol [C] 1997;118:89-95.
32. Okado-Matsumoto A, Fridovich I: Subcellular distributon of superoxide dismutases (SOD) in rat liver: Cu-, Zn-SOD in mitochondria. J Biol Chem 2001;276:38388-38393.
33. Lew H, Quintanilha A: Effects of endurance training and exercise on tissue anti-oxidative capacity and acetaminophen detoxification. Eur J Drug Metab Pharmacokinet 1991;16:59-68.
34. Schlorff EC, Husain K, Somani SM: Dose-and time-dependent effects of ethanol on plasma antioxidant system in rat. Alcohol 1999;17:97-105.
35. Husain K, Somani SM: Response of cardiac antioxidant system to alcohol and exercise training in the rat. Alcohol 1997;14:301- 307.
36. Gardner P, Fridovich I: Controls on the biosynthesis of the manganese-containing superoxide dismutase of Escherichia coli. J Biol Chem 1987;262:17591-17595.
37. Fernandez V, Videla IA: Effect of acute and chronic ethanol ingestion on the content of reduced glutathione on various tissues of the rat. Experientia 1981;37:392-394.
38. Jaya DS, Augstine J, Menon VP: Role of lipid peroxides, glu- tathione and antiperoxidative enzymes in alcohol and drug tox- icity. Indian J Exp Biol 1993;31:453-459.
39. Kosower NS, Kosower EM: The glutathione status of cells. Int Rev Cytol 1979;54:109-112.
40. Rajurkar RB, Khan ZH, Gujar GT: Studies on levels of glutathione- S-transferase, its isolation and purification from Helicoverpa armingera. Curr Sci 2003;85:1355-1360.
41. Hayes JD, Pulford DJ: The glutathione S-transferase supergene family: regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistance. CRC Crit Rev Biochem Mol Biol 1995;30:445-600.
42. Farombi EO, Nwaokeafor IA: Anti-oxidant mechanisms of ko- laviron: studies on serum lipoprotein oxidation, metal chelation and oxidative membrane damage in rats. Clin Exp Pharmacol Physiol 2005;32:667-674.