Synthesis and biological evaluation of C7-demethyl largazole analogues

ChemMedChem

Volumn 4, Issue 8, 2009, Pages 1269-1272

  Chen, Fei ^a   Gao, An Hui ^a   Li, Jia ^a   Nan, Fa Jun ^a  

^a SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

Antitumor agents; HDAC; Inhibitors; Largazole analogues; Molecular modeling

Indexed keywords

DEMETHYL LARGAZOLE; DEPSIPEPTIDE; HISTONE DEACETYLASE 1; UNCLASSIFIED DRUG;

ARTICLE; CRYSTAL STRUCTURE; DEPROTECTION REACTION; ENZYME ACTIVITY; ENZYME INHIBITION; HYDROLYSIS; PRIORITY JOURNAL; PROTEIN STRUCTURE; SYNTHESIS;

ANTINEOPLASTIC AGENTS; BINDING SITES; CELL LINE, TUMOR; COMPUTER SIMULATION; DEPSIPEPTIDES; HISTONE DEACETYLASES; HUMANS; RECOMBINANT PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP; THIAZOLES;

EID: 68149161259     PISSN: 18607179     EISSN: 18607187     Source Type: Journal    
DOI: 10.1002/cmdc.200900125     Document Type: Article

References (20)

1. K. Taori, V. J. Paul, H. Luesch, J. Am. Chem. Soc. 2008, 130, 1806.
2. Y.-C. Ying, K. Taori, H. Kim, J.-Y. Hong, H. Luesch, J. Am. Chem. Soc. 2008, 130, 8455.
3. P. A. Marks, Oncogene 2007, 26, 1351.
4. T. A. Miller, D. J. Witter, S. Belvedere, J. Med. Chem. 2003, 46, 5097.
5. R. R. Rosato, S. Grant, Expert Opin. Invest. Drugs 2004, 13, 21.
6. C. Monneret, Eur. J. Med. Chem. 2005, 40, 1.
7. C. B. Yoo, P. A. Jones, Nat. Rev. Drug Discovery 2006, 5, 37.
8. C. G. Nasveschuk, D. Ungermannova, X.-D. Liu, A. J. Phillips, Org. Lett. 2008, 10, 3595.
9. A. Bowers, N. West, J. Taunton, S. L. Schreiber, J. E. Bradner, R. M. Williams, J. Am. Chem. Soc. 2008, 130, 11219.
10. A. K. Ghosh, S. Kulkarni, Org. Lett. 2008, 10, 3907.
11. Y.-C. Ying, Y.-X. Liu, S. R. Byeon, H. Kim, H. Luesch, J.-Y. Hong, Org. Lett. 2008, 10, 4021.
12. T. Seiser, F. Kamena, N. Cramer, Angew. Chem. 2008, 120, 6583;
13. Angew. Chem. Int. Ed. 2008, 47, 6483.
14. S. N. Rao, M. S. Head, A. Kulkarni, J. M. LaLonde, J. Chem. Inf. Model. 2007, 47, 2159.
15. M. S. Finnin, J. R. Donigian, A. Cohen, V. M. Richon, R. A. Rifkind, P. A. Marks, R. Breslow, N. P. Pavletich, Nature 1999, 401, 188.
16. M. W. Bredenkamp, C. W. Holzapfel, W. J. van Zyl, Synth. Commun. 1990, 20, 2235.
17. R. Peters, M. Althaus, C. Diolez, A. Rolland, E. Manginot, M. Veyrat, J. Org. Chem. 2006, 71, 7583.
18. F. Denizot, R. Lang, J. Immunol. Methods 1986, 89, 271.
19. D. Gerlier, N. Thomasset, J. Immunol. Methods 1986, 94, 57.
20. A. A. Bowers, T. J. Greshock, N. West, G. Estiu, S. L. Schreiber, O. Wiest, R. M. Williams, J. E. Bradner, J. Am. Chem. Soc. 2009, 131, 2900.