Mutations in conserved amino acids in the KCNQ1 channel and risk of cardiac events in type-1 long-QT syndrome

Journal of Cardiovascular Electrophysiology

Volumn 20, Issue 8, 2009, Pages 859-865

  Jons, Christian ^a,b   Moss, Arthur J ^a   Lopes, Coeli M ^a   McNitt, Scott ^a   Zareba, Wojciech ^a   Goldenberg, Ilan ^a   Qi, Ming ^a   Wilde, Arthur A M ^d   Shimizu, Wataru ^c   Kanters, Jorgen K ^b,e   Towbin, Jeffrey A ^f   Ackerman, Michael J ^g   Robinson, Jennifer L ^a  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^b Mental Health Services CPH   (Denmark)

^c NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

^d UNIVERSITY OF AMSTERDAM   (Netherlands)

^e UNIVERSITY OF COPENHAGEN   (Denmark)

^f TEXAS CHILDREN S HOSPITAL   (United States)

^g Mayo Clinic   (United States)

Author keywords

Conservation; KCNQ1; Long QT syndrome; Shannon entropy; Sudden cardiac death

Indexed keywords

BETA ADRENERGIC RECEPTOR BLOCKING AGENT; POTASSIUM CHANNEL KCNQ1;

ADULT; AMINO ACID SEQUENCE; ARTICLE; FEMALE; HEART ARREST; HEART DEATH; HUMAN; LONG QT SYNDROME; MAJOR CLINICAL STUDY; MALE; MISSENSE MUTATION; PRIORITY JOURNAL; SCORING SYSTEM; SUDDEN DEATH; SYNCOPE;

ADOLESCENT; ADULT; AMINO ACID SEQUENCE; CARDIOVASCULAR DISEASES; CHILD; CHILD, PRESCHOOL; COMPUTATIONAL BIOLOGY; CONSERVED SEQUENCE; FEMALE; FOLLOW-UP STUDIES; HUMANS; INFANT; INFANT, NEWBORN; KCNQ1 POTASSIUM CHANNEL; MALE; MOLECULAR SEQUENCE DATA; MUTATION, MISSENSE; RISK FACTORS; ROMANO-WARD SYNDROME; YOUNG ADULT;

EID: 68149102945     PISSN: 10453873     EISSN: 15408167     Source Type: Journal    
DOI: 10.1111/j.1540-8167.2009.01455.x     Document Type: Article

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