Impact of lactic acid on cell proliferation and free radical-induced cell death in monolayer cultures of neural precursor cells

Biotechnology and Bioengineering

Volumn 103, Issue 6, 2009, Pages 1214-1223

  Lampe, Kyle J ^a   Namba, Rachael M ^b   Silverman, Tyler R ^a   Bjugstad, Kimberly B ^c   Mahoney, Melissa J ^a  

^a University of Colorado at Boulder   (United States)

^b UNIVERSITY OF COLORADO   (United States)

^c University of Colorado Denver and Children s Hospital Colorado   (United States)

Author keywords

Biodegradable; Biomaterial; Lactic acid; Neural precursor cell; Reactive oxygen species; Redox

Indexed keywords

ANTIOXIDANT PROPERTIES; BIODEGRADABLE; CELL COMPOSITION; CELL POPULATIONS; DEGRADABLE BIOMATERIALS; GLYCOLIC ACIDS; METABOLIC FUNCTION; MONOLAYER CULTURE; NATURALLY OCCURRING; NEURAL CELLS; NEURAL PRECURSOR CELL; NEURAL PRECURSORS; NEURAL TISSUE REGENERATION; PHOTO-INITIATOR; PRESENCE OF WATER; REACTIVE OXYGEN SPECIES; REDOX; REDOX STATE;

BIOMATERIALS; BODY FLUIDS; CELL DEATH; CELL MEMBRANES; CELL PROLIFERATION; DEGRADATION; FREE RADICAL REACTIONS; FREE RADICALS; HYDROGEN; HYDROGEN PEROXIDE; LACTIC ACID; METABOLISM; MONOLAYERS; ORGANIC ACIDS; OXYGEN;

CELL CULTURE;

FREE RADICAL; HYDROGEN PEROXIDE; LACTIC ACID;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL COMPOSITION; CELL DAMAGE; CELL DEATH; CELL POPULATION; CELL PROLIFERATION; CONTROLLED STUDY; DNA CONTENT; EMBRYO; IMMUNOCYTOCHEMISTRY; MONOLAYER CULTURE; NEURAL STEM CELL; NONHUMAN; OXIDATION REDUCTION STATE; POLYMERIZATION; RAT; REAL TIME POLYMERASE CHAIN REACTION;

CELL CULTURE TECHNIQUES; CELL PROLIFERATION; CELL SURVIVAL; FREE RADICAL SCAVENGERS; FREE RADICALS; LACTIC ACID; NERVE TISSUE; STEM CELLS;

EID: 68149092113     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.22352     Document Type: Article

References (33)

1. Alberts B, Bray D, Johnson A, Lewis J, Raff M, Roberts K, Walter P. 1998. Essential cell biology. New York: Garland Publishing, Inc.
2. Anbar M, Neta P. 1967. A compilation of specific bimolecular rate constants for reactions of hydrated electrons hydrogen atoms and hydroxyl radicals with inorganic and organic compounds in aqueous solution. Int J Appl Radiat Isot 18(7): 493-523.
3. Armstrong RJE, Watts C, Svendsen CN, Dunnett SB, Rosser AE. 2000. Survival, neuronal differentiation, and fiber outgrowth of propagated human neural precursor grafts in an animal model of Huntington's disease. Cell Transplant 9(1):55-64. (Pubitemid 30438906)
4. Bryant SJ, Nuttelman CR, Anseth KS. 2000. Cytocompatibility of UV and visible light photoinitiating systems on cultured NIH/3T3 fibroblasts in vitro. J Biomater Sci Polym Ed 11(5):439-457.
5. Buettner GR. 1993. The pecking order of free-radicals and antioxidants - Lipid-peroxidation, alpha-tocopherol, and ascorbate. Arch Biochem Biophys 300(2):535-543. (Pubitemid 23232908)
6. Degroot MJM, Vanhelden MAB, Dejong YF, Coumans WA, Vandervusse GJ. 1995. The influence of lactate, pyruvate and glucose as exogenous substrates on free-radical defense-mechanisms in isolated rat hearts during ischemia and reperfusion. Mol Cell Biochem 146(2):147-155.
7. Dringen R, Gutterer JM, Hirrlinger J. 2000. Glutathione metabolism in brain - Metabolic interaction between astrocytes and neurons in the defense against reactive oxygen species. Eur J Biochem 267(16):4912-4916. (Pubitemid 30641287)
8. Fridovich I. 1978. Biology of oxygen radicals. Science 201(4359):875-880.
9. Gage FH, Coates PW, Palmer TD, Kuhn HG, Fisher LJ, Suhonen JO, Peterson DA, Suhr ST, Ray J. 1995. Survival and differentiation of adult neuronal progenitor cells transplanted to the adult brain. Proc Natl Acad Sci USA 92(25):11879-11883. (Pubitemid 26014213)
10. Groussard C, Morel I, Chevanne M, Monnier M, Cillard J, Delamarche A. 2000. Free radical scavenging and antioxidant effects of lactate ion: An in vitro study. J Appl Physiol 89(1):169-175. (Pubitemid 30482577)
11. Halliwell B, Gutteridge JM. 1999. Free radicals in biology and medicine. New York: Oxford University Press.
12. Hashimoto JG, Beadles-Bohling AS, Wiren KM. 2004. Comparison of RiboGreen (R) and 18S rRNA quantitation for normalizing real-time RT-PCR expression analysis. Biotechniques 36(1):54-60.
13. Herz H, Blake DR, Grootveld M. 1997. Multicomponent investigations of the hydrogen peroxide- and hydroxyl radical-scavenging antioxidant capacities of biofluids: The roles of endogenous pyruvate and lactate - Relevance to inflammatory joint diseases. Free Radic Res 26(1):19-35. (Pubitemid 27060126)
14. Kamata H, Hirata H. 1999. Redox regulation of cellular signalling. Cell Signal 11(1):1-14.
15. Kloosterboer JG. 1988. Network formation by chain crosslinking photopolymerization and its applications in electronics. Adv Polym Sci 84:1-61.
16. Kweon SM, Kim HJ, Lee ZW, Kim SJ, Kim SI, Paik SG, Ha KS. 2001. Realtime measurement of intracellular reactive oxygen species using mito tracker orange (CMH(2)TMRos). Biosci Rep 21(3):341-352.
17. Lindvall O, Brundin P, Widner H, Rehncrona S, Gustavii B, Frackowiak R, Leenders KL, Sawle G, Rothwell JC, Marsden CD, Bjorklund A. 1990. Grafts of fetal dopamine neurons survive and improve motor function in Parkinsons-disease. Science 247(4942):574-577. (Pubitemid 20073682)
18. Mallet RT. 2000. Pyruvate: Metabolic protector of cardiac performance. Proc Soc Exp Biol Med 223(2):136-148.
19. McCord JM, Fridovich I. 1978. Biology and pathology of oxygen radicals. Ann Intern Med 89(1):122-127.
20. O'Brien AK, Bowman CN. 2006. Impact of oxygen on photopolymerization kinetics and polymer structure. Macromolecules 39(7):2501-2506.
21. Oka S, Honmou O, Akiyama Y, Sasaki M, Houkin K, Hashi K, Kocsis JD. 2004. Autologous transplantation of expanded neural precursor cells into the demyelinated monkey spinal cord. Brain Res 1030(1):94-102. (Pubitemid 39563830)
22. Philp A, Macdonald AL, Watt PW. 2005. Lactate - A signal coordinating cell and systemic function. J Exp Biol 208(24):4561-4575. (Pubitemid 43120002)
23. Pluchino S, Quattrini A, Brambilla E, Gritti A, Salani G, Dina G, Galli R, Del Carro U, Amadio S, Bergami A, Furlan R, Comi G, Vescovi AL, Martino G. 2003. Injection of adult neurospheres induces recovery in a chronic model of multiple sclerosis. Nature 422(6933):688-694. (Pubitemid 36514101)
24. Rutz HP, Little JB. 1995. Exogenous lactate interferes with cell-cycle control in Balb/3t3 mouse fibroblasts. Int J Radiat Oncol Biol Phys 31(3):525-528.
25. Schulz JB, Lindenau J, Seyfried J, Dichgans J. 2000. Glutathione, oxidative stress and neurodegeneration. Eur J Biochem 267(16):4904-4911.
26. Smith J, Ladi E, Mayer-Proschel M, Noble M. 2000. Redox state is a central modulator of the balance between self-renewal and differentiation in a dividing glial precursor cell. Proc Natl Acad Sci USA 97(18):10032-10037. (Pubitemid 30680850)
27. Studer L, Tabar V, McKay RDG. 1998. Transplantation of expanded mesencephalic precursors leads to recovery in Parkinsonian rats. Nat Neurosci 1(4):290-295. (Pubitemid 128652675)
28. Studer L, Csete M, Lee SH, Kabbani N, Walikonis J, Wold B, McKay R. 2000. Enhanced proliferation, survival, and dopaminergic differentiation of CNS precursors in lowered oxygen. J Neurosci 20(19):7377-7383. (Pubitemid 30747434)
29. Tsatmali M, Walcott EC, Crossin KL. 2005. Newborn neurons acquire high levels of reactive oxygen species and increased mitochondrial proteins upon differentiation from progenitors. Brain Res 1040(1-2):137-150. (Pubitemid 40459629)
30. Tsatmali M, Walcott EC, Makarenkova H, Crossin KL. 2006. Reactive oxygen species modulate the differentiation of neurons in clonal cortical cultures. Mol Cell Neurosci 33(4):345-357. (Pubitemid 44820854)
31. Vicario C, Medina JM. 1992. Metabolism of lactate in the rat-brain during the early neonatal-period. J Neurochem 59(1):32-40.
32. Williams CG, Malik AN, Kim TK, Manson PN, Elisseeff JH. 2005. Variable cytocompatibility of six cell lines with photoinitiators used for polymerizing hydrogels and cell encapsulation. Biomaterials 26(11):1211-1218.
33. Yanagida S, Luo CS, Doyle M, Pohost GM, Pike MM. 1995. Nuclear-magnetic-resonance studies of cationic and energetic alterations with oxidant stress in the perfused heart - Modulation with pyruvate and lactate. Circ Res 77(4):773-783.