-
1
-
-
0017595572
-
Timolol, a beta-adrenergic blocking agent for the treatment of glaucoma
-
Zimmerman, T.J., and Kaufman, H.E. Timolol, a beta-adrenergic blocking agent for the treatment of glaucoma. Arch Ophthalmol. 95:601-604, 1977. (Pubitemid 8263098)
-
(1977)
Archives of Ophthalmology
, vol.95
, Issue.4
, pp. 601-604
-
-
Zimmerman, T.J.1
Kaufman, H.E.2
-
2
-
-
0017605449
-
Timolol, dose response and duration of action
-
Zimmerman, T.J., and Kaufman, H.E. Timolol, dose response and duration of action. Arch Ophthalmol. 95:605-607, 1977.
-
(1977)
Arch Ophthalmol
, vol.95
, pp. 605-607
-
-
Zimmerman, T.J.1
Kaufman, H.E.2
-
3
-
-
0018751452
-
The beta adrenergic blocking agents and the treatment of glaucoma
-
DOI 10.1016/0039-6257(79)90228-5
-
Zimmerman, T. J., and Boger, W.P. III. The beta-adrenergic blocking agents and the treatment of glaucoma. Surv. Ophthalmol. 23:347-362, 1979. (Pubitemid 9199790)
-
(1979)
Survey of Ophthalmology
, vol.23
, Issue.6
, pp. 347-362
-
-
Zimmerman, T.J.1
Boger III, W.P.2
-
4
-
-
0017852447
-
Clinical trial comparing timolol ophthalmic solution to pilocarpine in openangle glaucoma
-
Boger, W.P. 3rd, Steinert, R.F., Puliafi to, C.A., et al. Clinical trial comparing timolol ophthalmic solution to pilocarpine in openangle glaucoma. Am. J. Ophthal. 86:9-18, 1978.
-
(1978)
Am. J. Ophthal.
, vol.86
, pp. 9-18
-
-
Boger III, W.P.1
Steinert, R.F.2
Puliafi To, C.A.3
-
5
-
-
69249110344
-
Sustained delivery of timolol maleate from poly(lactic-co-glycolic acid)/poly(lactic acid) microspheres for over 3 months
-
Bertram, J.P., Saluja, S.S., McKain, J., et al. Sustained delivery of timolol maleate from poly(lactic-co-glycolic acid)/poly(lactic acid) microspheres for over 3 months. J. Microencapsul. 24:1-8, 2008.
-
(2008)
J. Microencapsul.
, vol.24
, pp. 1-8
-
-
Bertram, J.P.1
Saluja, S.S.2
McKain, J.3
-
6
-
-
0035661823
-
Cardiovascular considerations in using topical, oral, and intravenous drugs for the treatment of glaucoma and ocular hypertension: Focus on beta-adrenergic blockade
-
Frishman, W.H., Kowalski, M., Nagnur, S., et al. Cardiovascular considerations in using topical, oral, and intravenous drugs for the treatment of glaucoma and ocular hypertension: focus on beta-adrenergic blockade. Heart Dis. 3:386-397, 2001. (Pubitemid 34003379)
-
(2001)
Heart Disease
, vol.3
, Issue.6
, pp. 386-397
-
-
Frishman, W.H.1
Kowalski, M.2
Nagnur, S.3
Warshafsky, S.4
Sica, D.5
-
7
-
-
33846467032
-
Open-angle glaucoma and cardiovascular mortality
-
Meyer, N.I. Open-angle glaucoma and cardiovascular mortality. Ophthalmology. 114:392, 2007.
-
(2007)
Ophthalmology
, vol.114
, pp. 392
-
-
Meyer, N.I.1
-
8
-
-
0242363251
-
With your genes? Take one of these, three times a day
-
DOI 10.1038/425760a
-
Abbott, A. With your genes? Take one of these, three times a day. Nature. 425:760-762, 2003. (Pubitemid 37351443)
-
(2003)
Nature
, vol.425
, Issue.6960
, pp. 760-762
-
-
Abbott, A.1
-
10
-
-
0020038842
-
Pharmacokinetics of topically applied ophthalmic drugs
-
Shell, J.W. Pharmacokinetics of topically applied ophthalmic drugs. Surv. Ophthalmol. 26:207-218, 1982.
-
(1982)
Surv. Ophthalmol.
, vol.26
, pp. 207-218
-
-
Shell, J.W.1
-
11
-
-
0036956566
-
Systemic bioavailability and cardiopulmonary effects of 0.5% timolol eyedrops
-
DOI 10.1007/s00417-002-0462-2
-
Korte, J.M., Kaila, T., and Saari, K.M. Systemic bioavailability and cardiopulmonary effects of 0.5% timolol eyedrops. Graefes Arch Clin. Exp. Ophthalmol. 240:430-435, 2002. (Pubitemid 36097063)
-
(2002)
Graefe's Archive for Clinical and Experimental Ophthalmology
, vol.240
, Issue.6
, pp. 430-435
-
-
Korte, J.-M.1
Kaila, T.2
Saari, K.M.3
-
12
-
-
33947146094
-
Ophthalmic timolol: Plasma concentration and systemic cardiopulmonary effects
-
DOI 10.1080/00365510601034736, PII 772869876
-
Nieminen, T., Lehtimäki, T., Mäenpää, J., et al. Ophthalmic timolol: plasma concentration and systemic cardiopulmonary effects. Scand J. Clin. Lab. Invest. 67:237-245, 2007. (Pubitemid 46410612)
-
(2007)
Scandinavian Journal of Clinical and Laboratory Investigation
, vol.67
, Issue.2
, pp. 237-245
-
-
Nieminen, T.1
Lehtimaki, T.2
Maenpaa, J.3
Ropo, A.4
Uusitalo, H.5
Kahonen, M.6
-
13
-
-
0026099459
-
Beta-blocking effects of timolol at low plasma concentrations
-
Kaila, T., Huupponen, R., Karhuvaara, S., et al. Beta-blocking effects of timolol at low plasma concentrations. Clin. Pharmacol. Ther. 49:53-58, 1991.
-
(1991)
Clin. Pharmacol. Ther.
, vol.49
, pp. 53-58
-
-
Kaila, T.1
Huupponen, R.2
Karhuvaara, S.3
-
14
-
-
0344938358
-
Inhibition and induction of human cytochrome P450 (CYP) enzymes
-
DOI 10.1080/004982598238886
-
Pelkonen, O., Mäenpää, J., Taavitsainen, P., et al. Inhibition and induction of human cytochrome P450 (CYP) enzymes. Xenobiotica. 28:1203-1253, 1998. (Pubitemid 29017141)
-
(1998)
Xenobiotica
, vol.28
, Issue.12
, pp. 1203-1253
-
-
Pelkonen, O.1
Maenpaaj, J.2
Taavitsainen, P.3
Rautio, A.4
Raunio, H.5
-
15
-
-
0742286803
-
Cytochrome P450 2D6: Overview and update on pharmacology, genetics, biochemistry
-
DOI 10.1007/s00210-003-0832-2
-
Zanger, U.M., Raimundo, S., and Eichelbaum, M. Cytochrome P450 2D6: overview and update on pharmacology, genetics, biochemistry. Naunyn Schmiedebergs Arch. Pharmacol. 369:23-37, 2004. (Pubitemid 38161221)
-
(2004)
Naunyn-Schmiedeberg's Archives of Pharmacology
, vol.369
, Issue.1
, pp. 23-37
-
-
Zanger, U.M.1
Raimundo, S.2
Eichelbaum, M.3
-
16
-
-
20744455857
-
Identification and characterization of novel sequence variations in the cytochrome P4502D6 (CYP2D6) gene in African Americans
-
DOI 10.1038/sj.tpj.6500305
-
Gaedigk, A., Bhathena, A., Ndjountché, L., et al. Identifi cation and characterization of novel sequence variations in the cytochrome P4502D6 (CYP2D6) gene in African Americans. Pharmacogenomics J. 5:173-182, 2005. (Pubitemid 40852219)
-
(2005)
Pharmacogenomics Journal
, vol.5
, Issue.3
, pp. 173-182
-
-
Gaedigk, A.1
Bhathena, A.2
Ndjountche, L.3
Pearce, R.E.4
Abdel-Rahman, S.M.5
Alander, S.W.6
Bradford, L.D.7
Leeder, J.S.8
-
17
-
-
28344439669
-
Polymorphisms of genes CYP2D6, ADRB1 and GNAS1 in pharmacokinetics and systemic effects of ophthalmic timolol. A pilot study
-
DOI 10.1007/s00228-005-0052-4
-
Nieminen, T., Uusitalo, H., Mäenpää, J., et al. Polymorphisms of genes CYP2D6, ADRB1 and GNAS1 in pharmacokinetics and systemic effects of ophthalmic timolol. Eur. J. Clin. Pharmacol. 61:811-819, 2005. (Pubitemid 41720269)
-
(2005)
European Journal of Clinical Pharmacology
, vol.61
, Issue.11
, pp. 811-819
-
-
Nieminen, T.1
Uusitalo, H.2
Maenpaa, J.3
Turjanmaa, V.4
Rane, A.5
Lundgren, S.6
Ropo, A.7
Rontu, R.8
Lehtimaki, T.9
Kahonen, M.10
-
18
-
-
0031038038
-
Cytochrome P450 2D6 variants in a Caucasian population: Allele frequencies and phenotypic consequences
-
Sachse, C., Brockmöller, J., Bauer, S., et al. Cytochrome P450 2D6 variants in a Caucasian population: allele frequencies and phenotypic consequences. Am. J. Hum. Genet. 60:284-295, 1997. (Pubitemid 27058401)
-
(1997)
American Journal of Human Genetics
, vol.60
, Issue.2
, pp. 284-295
-
-
Sachse, C.1
Brockmoller, J.2
Bauer, S.3
Roots, I.4
-
19
-
-
33645109079
-
CYP2D6*36 gene arrangements within the cyp2d6 locus: Association of CYP2D6*36 with poor metabolizer status
-
Gaedigk, A., Bradford, L.D., Alander, S.W., et al. CYP2D6*36 gene arrangements within the cyp2d6 locus: association of CYP2D6*36 with poor metabolizer status. Drug Metab. Dispos. 34:563-569, 2006.
-
(2006)
Drug Metab. Dispos.
, vol.34
, pp. 563-569
-
-
Gaedigk, A.1
Bradford, L.D.2
Alander, S.W.3
-
20
-
-
33947116593
-
Novel nonsynonymous single nucleotide polymorphisms in the CYP2D6 gene associated with CYP2D6*2 and/or CYP2D6*10 alleles
-
Soyama, A., Saito, Y., Komamura, K., et al. Novel nonsynonymous single nucleotide polymorphisms in the CYP2D6 gene associated with CYP2D6*2 and/or CYP2D6*10 alleles. Drug Metab. Pharmacokin. 17:475-478, 2002.
-
(2002)
Drug Metab. Pharmacokin.
, vol.17
, pp. 475-478
-
-
Soyama, A.1
Saito, Y.2
Komamura, K.3
-
21
-
-
14644445095
-
Results of the European Glaucoma Prevention Study
-
European Glaucoma Prevention Study (EGPS) Group
-
Miglior, S., Zeyen, T., Pfeiffer, N., et al.; European Glaucoma Prevention Study (EGPS) Group. Results of the European Glaucoma Prevention Study. Ophthalmology. 112:366-375, 2005.
-
(2005)
Ophthalmology
, vol.112
, pp. 366-375
-
-
Miglior, S.1
Zeyen, T.2
Pfeiffer, N.3
-
22
-
-
0028809608
-
Pharmacogenetic explanation for excessive beta-blockade following timolol eye drops. Potential for oral-ophthalmic drug interaction
-
Edeki, T.I., He, H., Wood, A.J. Pharmacogenetic explanation for excessive beta-blockade following timolol eye drops. Potential for oral-ophthalmic drug interaction. J. Am. Med. Assoc. 274:1611-11163, 1995.
-
(1995)
J. Am. Med. Assoc.
, vol.274
, pp. 1611-11163
-
-
Edeki, T.I.1
He, H.2
Wood, A.J.3
-
23
-
-
0033670208
-
Drug interaction between cimetidine and timolol ophthalmic solution: Effect on heart rate and intraocular pressure in healthy Japanese volunteers
-
Ishii, Y., Nakamura, K., Tsutsumi, K., et al. Drug interaction between cimetidine and timolol ophthalmic solution: effect on heart rate and intraocular pressure in healthy Japanese volunteers. J. Clin. Pharmacol. 40:193-199, 2000.
-
(2000)
J. Clin. Pharmacol.
, vol.40
, pp. 193-199
-
-
Ishii, Y.1
Nakamura, K.2
Tsutsumi, K.3
-
24
-
-
0029977239
-
Topical beta-adrenergic antagonists and quinidine: A risky interaction
-
Higginbotham, E.J. Topical beta-adrenergic antagonists and quinidine. A risky interaction. Arch. Ophthalmol. 114:745-746, 1996. (Pubitemid 26197010)
-
(1996)
Archives of Ophthalmology
, vol.114
, Issue.6
, pp. 745-746
-
-
Higginbotham, E.J.1
-
25
-
-
34447249286
-
Wpyw klomipraminy na aktywnosc CYP2D6 - Doniesienie wstepne
-
Szewczuk-Bogusławska, M., Kiejna, A., Grzesiak, M., et al. The infl uence of clomipramine on CYP2D6 activity. Psychiatr. Pol. 41:243-249, 2007. (Pubitemid 47074754)
-
(2007)
Psychiatria Polska
, vol.41
, Issue.2
, pp. 243-249
-
-
Szewczuk-Boguslawska, M.1
Kiejna, A.2
Grzesiak, M.3
Beszlej, J.A.4
Chlebowska, I.5
Orzechowska-Juzwenko, K.6
Milejski, P.7
-
27
-
-
28144455912
-
Beta-blockers to prevent gastroesophageal varies in patients with cirrhosis
-
Portal Hypertension Collaborative Group
-
Groszmann, R.J., Garcia-Tsao, G., Bosch, J., et al.; Portal Hypertension Collaborative Group. Beta-blockers to prevent gastroesophageal varies in patients with cirrhosis. N. Engl. J. Med. 353:2254-2261, 2005.
-
(2005)
N. Engl. J. Med.
, vol.353
, pp. 2254-2261
-
-
Groszmann, R.J.1
Garcia-Tsao, G.2
Bosch, J.3
-
28
-
-
33750607471
-
Analytical correction for multiple testing in admixture mapping
-
DOI 10.1159/000096094
-
Sha, Q., Zhang, X., Zhu, X., et al. Analytical correction for multiple testing in admixture mapping. Hum. Hered. 62:55-63, 2006. (Pubitemid 44689371)
-
(2006)
Human Heredity
, vol.62
, Issue.2
, pp. 55-63
-
-
Sha, Q.1
Zhang, X.2
Zhu, X.3
Zhang, S.4
-
29
-
-
38449087461
-
The clinical role of genetic polymorphisms in drug-metabolizing enzymes
-
Tomalik-Scharte, D., Lazar, A., Fuhr, U., et al. The clinical role of genetic polymorphisms in drug-metabolizing enzymes. Pharmacogenomics J. 8:4-15, 2008.
-
(2008)
Pharmacogenomics J
, vol.8
, pp. 4-15
-
-
Tomalik-Scharte, D.1
Lazar, A.2
Fuhr, U.3
-
30
-
-
34547138943
-
Evaluation of genetic factors for warfarin dose prediction
-
DOI 10.3121/cmr.2007.724
-
Caldwell, M.D., Berg, R.L., Zhang, K.Q., et al. Evaluation of genetic factors for warfarin dose prediction. Clin. Med. Res. 5:8-16, 2007. (Pubitemid 350218774)
-
(2007)
Clinical Medicine and Research
, vol.5
, Issue.1
, pp. 8-16
-
-
Caldwell, M.D.1
Berg, R.L.2
Kai, Q.Z.3
Glurich, I.4
Schmelzer, J.R.5
Yale, S.H.6
Vidaillet, H.J.7
Burmester, J.K.8
-
31
-
-
34250354021
-
Antipsychotic drugs and QTc prolongation: The potential role of CYP2D6 genetic polymorphism
-
DOI 10.1517/17425255.3.1.9
-
Dorado, P., Berecz, R., Peñas-Lledó, E.M., et al. Antipsychotic drugs and QTc prolongation: the potential role of CYP2D6 genetic polymorphism. Expert Opin. Drug Metab. Toxicol. 3:9-19, 2007. (Pubitemid 47315416)
-
(2007)
Expert Opinion on Drug Metabolism and Toxicology
, vol.3
, Issue.1
, pp. 9-19
-
-
Dorado, P.1
Berecz, R.2
Penas-LLedo, E.M.3
Llerena, A.4
-
32
-
-
33645113878
-
The relevance of CYP2D6 genetic polymorphism on chronic metoprolol therapy in cardiovascular patients
-
Ismail, R., and Teh, L.K. The relevance of CYP2D6 genetic polymorphism on chronic metoprolol therapy in cardiovascular patients. J. Clin. Pharm. Ther. 31:99-109, 2006.
-
(2006)
J. Clin. Pharm. Ther.
, vol.31
, pp. 99-109
-
-
Ismail, R.1
Teh, L.K.2
-
33
-
-
22944482153
-
Impact of the CYP2D6 ultra-rapid metabolizer genotype on doxepin pharmacokinetics and serotonin in platelets
-
Kirchheiner, J., Henckel, H.B., Franke, L., et al. Impact of the CYP2D6 ultra-rapid metabolizer genotype on doxepin pharmacokinetics and serotonin in platelets. Pharmacogenet. Genomics. 15:579-587, 2005. (Pubitemid 41044244)
-
(2005)
Pharmacogenetics and Genomics
, vol.15
, Issue.8
, pp. 579-587
-
-
Kirchheiner, J.1
Henckel, H.-B.2
Franke, L.3
Meineke, I.4
Tzvetkov, M.5
Uebelhack, R.6
Roots, I.7
Brockmoller, J.8
-
34
-
-
34548650021
-
CYP2D6 polymorphisms and the impact on tamoxifen therapy
-
Beverage, J.N., Sissung, T.M., Sion, A.M., et al. CYP2D6 polymorphisms and the impact on tamoxifen therapy. J. Pharm. Sci. 96:2224-2231, 2007.
-
(2007)
J. Pharm. Sci.
, vol.96
, pp. 2224-2231
-
-
Beverage, J.N.1
Sissung, T.M.2
Sion, A.M.3
-
35
-
-
34249084393
-
CYP-mediated clozapine interactions: How predictable are they?
-
DOI 10.2174/138920007780655469
-
Chetty, M., and Murray, M. CYP-mediated clozapine interactions: how predictable are they? Curr. Drug Metab. 8:307-313, 2007. (Pubitemid 46780060)
-
(2007)
Current Drug Metabolism
, vol.8
, Issue.4
, pp. 307-313
-
-
Chetty, M.1
Murray, M.2
-
36
-
-
34247229036
-
CYP2D6 genotype in relation to perphenazine concentration and pituitary pharmacodynamic tissue sensitivity in Asians: CYP2D6-serotonin-dopamine crosstalk revisited
-
DOI 10.1097/FPC.0b013e32801a3c10, PII 0121301120070500000005
-
Ozdemir, V., Bertilsson, L., Miura, J., et al. CYP2D6 genotype in relation to perphenazine concentration and pituitary pharmacodynamic tissue sensitivity in Asians: CYP2D6-serotonindopamine crosstalk revisited. Pharmacogenet. Genomics. 17:339-347, 2007. (Pubitemid 46608541)
-
(2007)
Pharmacogenetics and Genomics
, vol.17
, Issue.5
, pp. 339-347
-
-
Ozdemir, V.1
Bertilsson, L.2
Miura, J.3
Carpenter, E.4
Reist, C.5
Harper, P.6
Widen, J.7
Svensson, J.-O.8
Albers, L.J.9
Kennedy, J.L.10
Endrenyi, L.11
Kalow, W.12
-
37
-
-
0026099459
-
Beta-blocking effects of timolol at low plasma concentrations
-
Kaila, T., Huupponen, R., Karhuvaara, S., et al. Beta-blocking effects of timolol at low plasma concentrations. Clin. Pharmacol. Ther. 49:53-58, 1991.
-
(1991)
Clin. Pharmacol. Ther.
, vol.49
, pp. 53-58
-
-
Kaila, T.1
Huupponen, R.2
Karhuvaara, S.3
-
38
-
-
23944527343
-
Effect of CYP2D6*10 allele on the pharmacokinetics of loratadine in Chinese subjects
-
DOI 10.1124/dmd.105.005025
-
Yin, O.Q., Shi, X.J., Tomlinson, B., et al. Effect of CYP2D6*10 allele on the pharmacokinetics of loratadine in Chinese subjects. Drug Metab. Dispos. 33:1383-1387, 2005. (Pubitemid 41196969)
-
(2005)
Drug Metabolism and Disposition
, vol.33
, Issue.9
, pp. 1283-1287
-
-
Yin, O.Q.P.1
Shi, X.J.2
Tomlinson, B.3
Chow, M.S.S.4
-
39
-
-
0043127371
-
Post-mortem SNP analysis of CYP2D6 gene reveals correlation between genotype and opioid drug (tramadol) metabolite ratios in blood
-
DOI 10.1016/S0379-0738(03)00159-2
-
Levo, A., Koski, A., Ojanperä, I., et al. Post-mortem SNP analysis of CYP2D6 gene reveals correlation between genotype and opioid drug (tramadol) metabolite ratios in blood. Forensic Sci. Int. 135:9-15, 2003. (Pubitemid 36957845)
-
(2003)
Forensic Science International
, vol.135
, Issue.1
, pp. 9-15
-
-
Levo, A.1
Koski, A.2
Ojanpera, I.3
Vuori, E.4
Sajantila, A.5
-
40
-
-
26244441576
-
Polymorphism of the beta-2 adrenoceptor and IOP lowering potency of topical timolol in healthy subjects
-
Fuchsjager-Mayrl, G., Markovic, O., Losert, D., et al. Polymorphism of the beta-2 adrenoceptor and IOP lowering potency of topical timolol in healthy subjects. Mol. Vis. 11:811-815, 2005. (Pubitemid 41410190)
-
(2005)
Molecular Vision
, vol.11
, pp. 811-815
-
-
Fuchsjager-Mayrl, G.1
Markovic, O.2
Losert, D.3
Lucas, T.4
Wachek, V.5
Muller, M.6
Schmetterer, L.7
-
41
-
-
33947146094
-
Ophthalmic timolol: Plasma concentration and systemic cardiopulmonary effects
-
DOI 10.1080/00365510601034736, PII 772869876
-
Nieminen, T., Lehtimäki, T., Mäenpää, J., et al. Ophthalmic timolol: plasma concentration and systemic cardiopulmonary effects. Scand. J. Clin. Lab. Invest. 67:237-245, 2007. (Pubitemid 46410612)
-
(2007)
Scandinavian Journal of Clinical and Laboratory Investigation
, vol.67
, Issue.2
, pp. 237-245
-
-
Nieminen, T.1
Lehtimaki, T.2
Maenpaa, J.3
Ropo, A.4
Uusitalo, H.5
Kahonen, M.6
|