Evaluation of hydrogen bonds of ecdysteroids in the ligand-receptor interactions using a protein modeling system

Bioorganic and Medicinal Chemistry

Volumn 17, Issue 16, 2009, Pages 5868-5873

  Harada, Toshiyuki ^a   Nakagawa, Yoshiaki ^a   Akamatsu, Miki ^a   Miyagawa, Hisashi ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

CoMFA; Drosophila melanogaster; Ecdysone receptor; FAMS; Hydrogen bond; Ponasterone A; QSAR

Indexed keywords

ECDYSONE RECEPTOR; ECDYSTEROID; ECDYSTERONE; PONASTERONE A;

ARTICLE; BINDING AFFINITY; COMPARATIVE MOLECULAR FIELD ANALYSIS; CORRELATION ANALYSIS; DROSOPHILA MELANOGASTER; DRUG RECEPTOR BINDING; HYDROGEN BOND; MOLECULAR MODEL; PROTEIN DOMAIN; QUANTITATIVE STRUCTURE ACTIVITY RELATION;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; COMPUTER SIMULATION; DROSOPHILA MELANOGASTER; ECDYSTERONE; HYDROGEN BONDING; LIGANDS; MOLECULAR SEQUENCE DATA; PROTEIN ENGINEERING; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN STRUCTURE, TERTIARY; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; RECEPTORS, STEROID; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID;

DROSOPHILA MELANOGASTER; HEXAPODA;

EID: 68149089672     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2009.07.011     Document Type: Article

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