Synthesis of ponasterone A derivatives with various steroid skeleton moieties and evaluation of their binding to the ecdysone receptor of Kc cells

Steroids

Volumn 73, Issue 14, 2008, Pages 1452-1464

  Arai, Hirokazu ^a   Watanabe, Bunta ^a   Nakagawa, Yoshiaki ^a   Miyagawa, Hisashi ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

Drosophila; Ecdysone agonists; Ecdysone receptor; Kc cells; Ponasterone A

Indexed keywords

20,22 DIHYDROXYCHOLEST 5 ENE; 20,22 ISOPROPYLIDENEDIOXY 3BETA (P TOLUENESULFONYLOXY) 5ALPHA CHOLESTANE; 20,22 ISOPROPYLIDENEDIOXY 3BETA (TETRAHYDROPYRAN 2 YLOXY) 5ALPHA CHOLESTAN 6 ONE; 20,22 ISOPROPYLIDENEDIOXY 3BETA (TETRAHYDROPYRAN 2 YLOXY) 5ALPHA CHOLESTAN 6ALPHA OL; 20,22 ISOPROPYLIDENEDIOXY 3BETA (TETRAHYDROPYRAN 2 YLOXY)CHOLEST 5 ENE; 20,22 ISOPROPYLIDENEDIOXY 5ALPHA CHOLEST 2 EN 6 ONE; 20,22 ISOPROPYLIDENEDIOXY 5ALPHA CHOLESTANE; 20,22 ISOPROPYLIDENEDIOXYCHOLEST 5 ENE; 2BETA ACETOXY 3BETA HYDROXY 20,22 ISOPROPYLIDENEDIOXY 5ALPHA CHOLESTAN 6 ONE; 2BETA,3BETA DIHYDROXY 20,22 ISOPROPYLIDENEDIOXY 5ALPHA CHOLESTAN 6 ONE; 2BETA,3BETA DIHYDROXY 20,22 ISOPROPYLIDENEDIOXY 5BETA CHOLESTAN 6 ONE; 2BETA,3BETA,20,22 TETRAHYDROXY 5ALPHA CHOLESTAN 6 ONE; 2BETA,3BETA,20,22 TETRAHYDROXY 5BETA CHOLESTAN 6 ONE; 3ALPHA BENZOYLOXY 20,22 ISOPROPYLIDENEDIOXY 5ALPHA CHOLESTAN 6 ONE; 3ALPHA HYDROXY 20,22 ISOPROPYLIDENEDIOXY 5ALPHA CHOLESTAN 6 ONE; 3ALPHA HYDROXY 20,22 ISOPROPYLIDENEDIOXY 5BETA CHOLESTAN 6 ONE; 3ALPHA,20,22 TRIHYDROXY 5ALPHA CHOLESTAN 6 ONE; 3ALPHA,20,22 TRIHYDROXY 5BETA CHOLESTAN 6 ONE; 3BETA HYDROXY 20,22 ISOPROPYLIDENEDIOXY 5ALPHA CHOLESTAN 6 ONE; 3BETA,20,22 TRIHYDROXY 5ALPHA CHOLESTAN 6 ONE; 5ALPHA CHOLESTAN 3BETA,6BETA,20,22 TETRAOL; 5ALPHA CHOLESTANE 20,22 DIOL; 5ALPHA CHOLESTANE 3BETA,20,22 TRIOL; 5ALPHA CHOLESTANE 3BETA,6ALPHA,20,22 TETRAOL; BRASSINOLIDE; CASTASTERONE; CHOLEST 5 ENE 20,22 DIOL; ECDYSTERONE; PONASTERONE A; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; DROSOPHILA; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; HYDROGEN BOND; IC 50; INSECTICIDAL ACTIVITY; NONHUMAN; OXIDATION REDUCTION REACTION; SKELETON;

ANIMALS; CELLS, CULTURED; DROSOPHILA; ECDYSTERONE; MOLECULAR STRUCTURE; RECEPTORS, STEROID; STEROIDS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 55549142976     PISSN: 0039128X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.steroids.2008.08.005     Document Type: Article

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