Dyspnea and pain share emotion-related brain network

NeuroImage

Volumn 48, Issue 1, 2009, Pages 200-206

  von Leupoldt, Andreas ^a,b   Sommer, Tobias ^b   Kegat, Sarah ^a   Baumann, Hans Jörg ^b   Klose, Hans ^b   Dahme, Bernhard ^a   Büchel, Christian ^b  

^a UNIVERSITY OF HAMBURG   (Germany)

^b UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

Author keywords

Breathlessness; Dyspnea; Emotion; fMRI; Pain; Perception

Indexed keywords

ADAPTIVE BEHAVIOR; ADULT; AMYGDALOID NUCLEUS; ANXIETY; ARTICLE; BRAIN CORTEX; BRAIN FUNCTION; BRAIN REGION; CINGULATE GYRUS; CONTROLLED STUDY; DYSPNEA; EMOTION; FEAR; FEMALE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HEAT; HUMAN; HUMAN EXPERIMENT; HYPOTHESIS; INSULA; MALE; NEUROIMAGING; NORMAL HUMAN; PAIN; PERCEPTION; PRIORITY JOURNAL; STIMULUS; SURVIVAL; THALAMUS;

ADULT; BRAIN; BRAIN MAPPING; DYSPNEA; EMOTIONS; FEMALE; HOT TEMPERATURE; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; NEURAL PATHWAYS; PAIN;

EID: 68049148342     PISSN: 10538119     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroimage.2009.06.015     Document Type: Article

References (65)

1. Adolphs R., Gosselin F., Buchanan T.W., Tranel D., Schyns P., and Damasio A.R. A mechanism for impaired fear recognition after amygdala damage. Nature 433 (2005) 68-72
2. American Thoracic Society. Dyspnea: mechanisms, assessment, and management: a consensus statement. Am. J. Respir. Crit. Care Med. 159 (1999) 321-340
3. Amunts K., Kedo O., Kindler M., Pieperhoff P., Mohlberg H., Shah N.J., Habel U., Schneider F., and Zilles K. Cytoarchitectonic mapping of the human amygdala, hippocampal region and entorhinal cortex: intersubject variability and probability maps. Anat. Embryol. 210 (2005) 343-352
4. Augustine J.R. Circuitry and functional aspects of the insular lobe in primates including humans. Brain Res. Brain Res. Rev. 22 (1996) 229-244
5. Banzett R.B., and Moosavi S.H. Dyspnea and pain: similarities and contrasts between two very unpleasant sensations. APS Bull. 11 (2001) 1-8
6. Banzett R.B., Mulnier H.E., Murphy K., Rosen S.D., Wise R.J., and Adams L. Breathlessness in humans activates insular cortex. Neuroreport 11 (2000) 2117-2120
7. Banzett R.B., Dempsey J.A., O Donnell D.E., and Wamboldt M.Z. Symptom perception and respiratory sensation in asthma. Am. J. Respir. Crit. Care Med. 162 (2000) 1178-1182
8. Bingel U., Quante M., Knab R., Bromm B., Weiller C., and Büchel C. Single trial fMRI reveals significant contralateral bias in responses to laser pain within thalamus and somatosensory cortices. Neuroimage 18 (2003) 740-748
9. Borg G. Borg's Perceived Exertion and Pain Scales (1998), Human Kinetics Publishers, Champaign
10. Corfield D.R., Fink G.R., Ramsay S.C., Murphy K., Harty H.R., Watson J.D.G., Adams L., Frackoviak R.S.J., and Guz A. Evidence for limbic system activation during CO2-stimulated breathing in man. J. Physiol. 488 (1995) 77-84
11. Craig A.D. How do you feel? Interoception: the sense of the physiological condition of the body. Nat. Rev. Neurosci. 3 (2002) 655-666
12. Critchley H.D. Neural mechanisms of autonomic, affective, and cognitive integration. J. Comp. Neurol. 493 (2005) 154-166
13. Critchley H.D., Wiens S., Rotshtein P., Öhman A., and Dolan R.J. Neural systems supporting interoceptive awareness. Nat. Neurosci. 7 (2004) 189-195
14. Critchley H.D., Tang J., Glaser D., Butterworth B., and Dolan R.J. Anterior cingulate activity during error and autonomic response. Neuroimage 27 (2005) 885-895
15. Damasio A.R. Descartes' Error (1994), Putnam, Emotion, Reason, and the Human Brain. New York
16. Darwin C. The Expression of the Emotions in Man and Animals (1872), J. Murray, London
17. Davenport P.W., and Vovk A. Cortical and subcortical central neural pathways in respiratory sensations. Respir. Physiol. Neurobiol. 167 (2008) 72-86
18. Dunckley P., Wise R.G., Aziz Q., Painter D., Brooks J., Tracey I., and Chang L. Cortical processing of visceral and somatic stimulation: differentiating pain intensity from unpleasantness. Neuroscience 133 (2005) 533-542
19. Duranti R., Pantaleo T., Bellini F., Bongianni F., and Scano G. Respiratory responses induced by the activation of somatic nociceptive afferents in humans. J. Appl. Physiol. 71 (1991) 2440-2448
20. Etkin A., and Wager T.D. Functional neuroimaging of anxiety: a meta-analysis of emotional processing in PTSD, social anxiety disorder, and specific phobia. Am. J. Psychiatry 164 (2007) 1476-1488
21. Evans K.C., Banzett R.B., Adams L., McKay L., Frackowiak R.S., and Corfield D.R. BOLD fMRI identifies limbic, paralimbic, and cerebellar activation during air hunger. J. Neurophysiol. 88 (2002) 1500-1511
22. Farrell M.J., Egan G.F., Zamarripa F., Shade R., Blair-West J., Fox P., and Denton D.A. Unique, common, and interacting cortical correlates of thirst and pain. Proc. Natl. Acad. Sci. U. S. A. 103 (2006) 2416-2421
23. Fink G.R., Corfield D.R., Murphy K., Kobayashi I., Dettmers C., Adams L., Frackowiak R.S., and Guz A. Human cerebral activity with increasing inspiratory force: a study using positron emission tomography. J. Appl. Physiol. 81 (1996) 1295-1305
24. Friston K.J., Holmes A.P., Worsley K.J., Poline J.P., Frith C.D., and Frackowiak R.S.J. Statistical parametric maps in functional imaging: a general linear approach. Hum. Brain Mapp. 2 (1994) 189-210
25. Friston K.J., Ashburner J., Frith C.D., Poline J.P., Heather J.D., and Frackowiak R.S.J. Spatial registration and normalisation of images. Hum. Brain Mapp. 3 (1995) 165-189
26. Giardino N.D., Friedman S.D., and Dager S.R. Anxiety, respiration, and cerebral blood flow: implications for functional brain imaging. Compr. Psychiatry 48 (2007) 103-112
27. Gray M.A., Harrison N.A., Wiens S., and Critchley H.D. Modulation of emotional appraisal by false physiological feedback during fMRI. PLoS 2 (2007) e546
28. Hamelsky S.W., and Lipton R.B. Psychiatric comorbidity of migraine. Headache 46 (2006) 1327-1333
29. Harver A., and Mahler D.A. Perception of increased resistance to breathing. In: Kotses H., and Harver A. (Eds). Self-Management of Asthma (1998), Dekker, New York 35-61
30. Henderson L.A., Woo M.A., Macey P.M., Macey K.E., Frysinger R.C., Alger J.R., Yan-Go F., and Harper R.M. Neural responses during Valsalva maneuvers in obstructive sleep apnea syndrome. J. Appl. Physiol. 94 (2003) 1063-1074
31. International Association for the Study of Pain. Classification of Chronic Pain (1994), IASP Press, Seattle 209-214
32. Jabbi M., Swart M., and Keysers C. Empathy for positive and negative emotions in the gustatory cortex. Neuroimage 34 (2007) 1744-1753
33. James W. Physical basis of emotion. Psychol. Rev. 1 (1894) 516-529
34. Komisaruk B.R., Whipple B., Crawford A., Liu W.C., Kalnin A., and Mosier K. Brain activation during vaginocervical self-stimulation and orgasm in women with complete spinal cord injury: fMRI evidence of mediation by the vagus nerves. Brain Res. 1024 (2004) 77-88
35. Lansing R.W., Gracely R.H., and Banzett R.B. The multiple dimensions of dyspnea: review and hypotheses. Respir. Physiol. Neurobiol. 167 (2008) 53-60
36. Leeuw M., Goossens M.E., Linton S.J., Crombez G., Boersma K., and Vlaeyen J.W. The fear-avoidance model of musculoskeletal pain: current state of scientific evidence. J. Behav. Med. 30 (2007) 77-94
37. Liotti M., Brannan S., Egan G., Shade R., Madden L., Abplanalp B., Robillard R., Lancaster J., Zamarripa F.E., Fox P.T., and Denton D. Brain responses associated with consciousness of breathlessness (air hunger). Proc. Natl. Acad. Sci. U. S. A. 98 (2001) 2035-2040
38. Macey K.E., Macey P.M., Woo M.A., Henderson L.A., Frysinger R.C., Harper R.K., Alger J.R., Yan-Go F., and Harper R.M. Inspiratory loading elicits aberrant fMRI signal changes in obstructive sleep apnea. Respir. Physiol. Neurobiol. 151 (2006) 44-60
39. Maurer J., Rebbapragada V., Borson S., Goldstein R., Kunik M.E., Yohannes A.M., Hanania N.A., and ACCP Workshop Panel on Anxiety and Depression in COPD. Anxiety and depression in COPD: current understanding, unanswered questions, and research needs. Chest 134 4 Suppl. (2008) 43S-56S
40. McKay L.C., Adams L., Frackowiak R.S., and Corfield D.R. A bilateral cortico-bulbar network associated with breath holding in humans, determined by functional magnetic resonance imaging. Neuroimage 40 (2008) 1824-1832
41. Mobbs D., Petrovic P., Marchant J.L., Hassabis D., Weiskopf N., Seymour B., Dolan R.J., and Frith C.D. When fear is near: threat imminence elicits prefrontal-periaqueductal gray shifts in humans. Science 317 (2007) 1079-1083
42. Paulus M.P., and Stein M.B. An insular view of anxiety. Biol. Psychiatry 60 (2006) 383-387
43. Pattinson K.T., Mitsis G.D., Harvey A.K., Jbabdi S., Dirckx S., Mayhew S.D., Rogers R., Tracey I., and Wise R.G. Determination of the human brainstem respiratory control network and its cortical connections in vivo using functional and structural imaging. Neuroimage 44 (2009) 295-305
44. Peiffer C., Poline J.B., Thivard L., Aubier M., and Samson Y. Neural substrates for the perception of acutely induced dyspnea. Am. J. Respir. Crit. Care Med. 163 (2001) 951-957
45. Peiffer C. Dyspnea and emotion: what can we learn from functional brain imaging?. Am. J. Respir. Crit. Care Med. 177 (2008) 937-939
46. Peiffer C., Costes N., Hervé P., and Garcia-Larrea L. Relief of dyspnea involves a characteristic brain activation and a specific quality of sensation. Am. J. Respir. Crit. Care Med. 177 (2008) 440-449
47. Phillips M.L., Drevets W.C., Rauch S.L., and Lane R. Neurobiology of emotion perception I: the neural basis of normal emotion perception. Biol. Psychiatry 54 (2003) 504-514
48. Phillips M.L., Gregory L.J., Cullen S., Coen S., Ng V., Andrew C., Giampietro V., Bullmore E., Zelaya F., Amaro E., Thompson D.G., Hobson A.R., Williams S.C., Brammer M., and Aziz Q. The effect of negative emotional context on neural and behavioural responses to oesophageal stimulation. Brain 126 (2003) 669-684
49. Pollatos O., Kirsch W., and Schandry R. On the relationship between interoceptive awareness, emotional experience, and brain processes. Brain Res. Cogn. Brain Res. 25 (2005) 948-962
50. Pollatos O., Gramann K., and Schandry R. Neural systems connecting interoceptive awareness and feelings. Hum. Brain Mapp. 28 (2007) 9-18
51. Polli F.E., Barton J.J., Cain M.S., Thakkar K.N., Rauch S.L., and Manoach D.S. Rostral and dorsal anterior cingulate cortex make dissociable contributions during antisaccade error commission. Proc. Natl. Acad. Sci. U. S. A. 102 (2005) 15700-15705
52. Price D.D. Psychological and neural mechanisms of the affective dimension of pain. Science 288 (2000) 1769-1772
53. Rainville P., Duncan G.H., Price D.D., Carrier B., and Bushnell M.C. Pain affect encoded in human anterior cingulate but not somatosensory cortex. Science 277 (1997) 968-971
54. Schön D., Dahme B., and von Leupoldt A. Associations between the perception of dyspnea, pain and negative affect. Psychophysiology 45 (2008) 1064-1067
55. Schön D., Rosenkranz M., Regelsberger J., Dahme B., Büchel C., and von Leupoldt A. Reduced perception of dyspnea and pain after right insular cortex lesions. Am. J. Respir. Crit. Care Med. 178 (2008) 1173-1179
56. Schreckenberger M., Siessmeier T., Viertmann A., Landvogt C., Buchholz H.G., Rolke R., Treede R.D., Bartenstein P., and Birklein F. The unpleasantness of tonic pain is encoded by the insular cortex. Neurology 64 (2005) 1175-1183
57. Small D.M., Gregory M.D., Mak Y.E., Gitelman D., Mesulam M.M., and Parrish T. Dissociation of neural representation of intensity and affective valuation in human gustation. Neuron 39 (2003) 701-711
58. Takahashi H., Matsuura M., Koeda M., Yahata N., Suhara T., Kato M., and Okubo Y. Brain activations during judgments of positive self-conscious emotion and positive basic emotion: pride and joy. Cereb. Cortex 18 (2008) 898-903
59. Tataranni P.A., Gautier J.F., Chen K., Uecker A., Bandy D., Salbe A.D., Pratley R.E., Lawson M., Reiman E.M., and Ravussin E. Neuroanatomical correlates of hunger and satiation in humans using positron emission tomography. Proc. Natl. Acad. Sci. U. S. A. 96 (1999) 4569-4574
60. Tracey I., and Mantyh P.W. The cerebral signature for pain perception and its modulation. Neuron 55 (2007) 377-391
61. Tzourio-Mazoyer N., Landeau B., Papathanassiou D., Crivello F., Etard O., Delcroix N., Mazoyer B., and Joliot M. Automated anatomical labeling of activations in SPM using a macroscopic anatomical parcellation of the MNI MRI single-subject brain. Neuroimage 15 (2002) 273-289
62. Vogt B.A. Pain and emotion interactions in subregions of the cingulate gyrus. Nat. Rev. Neurosci. 6 (2005) 533-544
63. von Leupoldt A., and Dahme B. Cortical substrates for the perception of dyspnea. Chest 128 (2005) 345-354
64. von Leupoldt A., and Dahme B. Psychological aspects in the perception of dyspnea in obstructive pulmonary diseases. Respir. Med. 101 (2007) 411-422
65. von Leupoldt A., Sommer T., Kegat S., Baumann H.J., Klose H., Dahme B., and Büchel C. The unpleasantness of perceived dyspnea is processed in the anterior insula and amygdala. Am. J. Respir. Crit. Care. Med. 177 (2008) 1026-1032