메뉴 건너뛰기




Volumn 81, Issue 2, 2009, Pages 243-249

Rapid effect of GNRH1 on follicle-stimulating hormone beta gene expression in LbetaT2 mouse pituitary cells requires the progesterone receptor

Author keywords

ChIP; Coactivators; Follicle stimulating hormone; Gene regulation; Gonadotropin releasing hormone; Gonadotropins; Ligand independent activation; Mechanisms of hormone action; Progesterone receptor; Protein kinase C

Indexed keywords

2 [1 (3 DIMETHYLAMINOPROPYL) 3 INDOLYL] 3 (3 INDOLYL)MALEIMIDE; CYCLIC AMP DEPENDENT PROTEIN KINASE; FOLLITROPIN BETA SUBUNIT; GONADORELIN; MESSENGER RNA; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; PROGESTERONE RECEPTOR; PROTEIN KINASE C; SMALL INTERFERING RNA;

EID: 68049131575     PISSN: 00063363     EISSN: 15297268     Source Type: Journal    
DOI: 10.1095/biolreprod.109.076216     Document Type: Article
Times cited : (9)

References (46)
  • 2
    • 33749863310 scopus 로고    scopus 로고
    • Differential expression and regulation of progesterone receptor isoforms in rat and mouse pituitary cells and LbetaT2 gonadotropes
    • Turgeon JL, Waring DW. Differential expression and regulation of progesterone receptor isoforms in rat and mouse pituitary cells and LbetaT2 gonadotropes. J Endocrinol 2006; 190:837-846.
    • (2006) J Endocrinol , vol.190 , pp. 837-846
    • Turgeon, J.L.1    Waring, D.W.2
  • 3
    • 0036917921 scopus 로고    scopus 로고
    • Mechanism of action of progesterone antagonists
    • Leonhardt SA, Edwards DP. Mechanism of action of progesterone antagonists. Exp Biol Med (Maywood) 2002; 227:969-980.
    • (2002) Exp Biol Med (Maywood) , vol.227 , pp. 969-980
    • Leonhardt, S.A.1    Edwards, D.P.2
  • 4
    • 1442351143 scopus 로고    scopus 로고
    • Coregulator function: A key to understanding tissue specificity of selective receptor modulators
    • Smith CL, O'Malley BW. Coregulator function: a key to understanding tissue specificity of selective receptor modulators. Endocr Rev 2004; 25: 45-71.
    • (2004) Endocr Rev , vol.25 , pp. 45-71
    • Smith, C.L.1    O'Malley, B.W.2
  • 5
    • 0028358327 scopus 로고
    • The human progesterone receptor A-form functions as a transcriptional modulator of mineralocorticoid receptor transcriptional activity
    • McDonnell DP, Shahbaz MM, Vegeto E, Goldman ME. The human progesterone receptor A-form functions as a transcriptional modulator of mineralocorticoid receptor transcriptional activity. J Steroid Biochem Mol Biol 1994; 48:425-432.
    • (1994) J Steroid Biochem Mol Biol , vol.48 , pp. 425-432
    • McDonnell, D.P.1    Shahbaz, M.M.2    Vegeto, E.3    Goldman, M.E.4
  • 6
    • 29444449329 scopus 로고    scopus 로고
    • Steroid receptor coactivator (SRC)-1 and SRC-3 differentially modulate tissuespecific activation functions of the progesterone receptor
    • Han SJ, DeMayo FJ, Xu J, Tsai SY, Tsai MJ, O'Malley BW. Steroid receptor coactivator (SRC)-1 and SRC-3 differentially modulate tissuespecific activation functions of the progesterone receptor. Mol Endocrinol 2006; 20:45-55.
    • (2006) Mol Endocrinol , vol.20 , pp. 45-55
    • Han, S.J.1    DeMayo, F.J.2    Xu, J.3    Tsai, S.Y.4    Tsai, M.J.5    O'Malley, B.W.6
  • 7
    • 38749088733 scopus 로고    scopus 로고
    • Steroid receptor coactivator 2 is required for female fertility and mammary morphogenesis: Insights from the mouse, relevance to the human
    • Mukherjee A, Amato P, Allred DC, DeMayo FJ, Lydon JP. Steroid receptor coactivator 2 is required for female fertility and mammary morphogenesis: insights from the mouse, relevance to the human. Nucl Recept Signal 2007; 5:e011.
    • (2007) Nucl Recept Signal , vol.5
    • Mukherjee, A.1    Amato, P.2    Allred, D.C.3    DeMayo, F.J.4    Lydon, J.P.5
  • 8
    • 0028890442 scopus 로고
    • Ligand occupancy is not required for vitamin D receptor and retinoid receptor-mediated transcriptional activation
    • Matkovits T, Christakos S. Ligand occupancy is not required for vitamin D receptor and retinoid receptor-mediated transcriptional activation. Mol Endocrinol 1995; 9:232-242.
    • (1995) Mol Endocrinol , vol.9 , pp. 232-242
    • Matkovits, T.1    Christakos, S.2
  • 9
    • 0026317212 scopus 로고
    • Dopaminergic and ligand-independent activation of steroid hormone receptors
    • Power RF, Mani SK, Codina J, Conneely OM, O'Malley BW. Dopaminergic and ligand-independent activation of steroid hormone receptors. Science 1991; 254:1636-1639.
    • (1991) Science , vol.254 , pp. 1636-1639
    • Power, R.F.1    Mani, S.K.2    Codina, J.3    Conneely, O.M.4    O'Malley, B.W.5
  • 10
    • 0028037785 scopus 로고
    • Convergent pathways for steroid hormone- and neurotransmitter-induced rat sexual behavior
    • Mani SK, Allen JM, Clark JH, Blaustein JD, O'Malley BW. Convergent pathways for steroid hormone- and neurotransmitter-induced rat sexual behavior. Science 1994; 265:1246-1249.
    • (1994) Science , vol.265 , pp. 1246-1249
    • Mani, S.K.1    Allen, J.M.2    Clark, J.H.3    Blaustein, J.D.4    O'Malley, B.W.5
  • 11
    • 34948900221 scopus 로고    scopus 로고
    • Steroid receptor phosphorylation: A key modulator of multiple receptor functions
    • Weigel NL, Moore NL. Steroid receptor phosphorylation: a key modulator of multiple receptor functions. Mol Endocrinol 2007; 21:2311-2319.
    • (2007) Mol Endocrinol , vol.21 , pp. 2311-2319
    • Weigel, N.L.1    Moore, N.L.2
  • 12
    • 10044257416 scopus 로고    scopus 로고
    • Phosphorylation of progesterone receptor serine 400 mediates ligand-independent transcriptional activity in response to activation of cyclin-dependent protein kinase 2
    • Pierson-Mullany LK, Lange CA. Phosphorylation of progesterone receptor serine 400 mediates ligand-independent transcriptional activity in response to activation of cyclin-dependent protein kinase 2. Mol Cell Biol 2004; 24:10542-10557.
    • (2004) Mol Cell Biol , vol.24 , pp. 10542-10557
    • Pierson-Mullany, L.K.1    Lange, C.A.2
  • 13
  • 14
    • 33746382288 scopus 로고    scopus 로고
    • Protein kinase C cross-talk with gonadotrope progesterone receptor is involved in GnRH-induced LH secretion
    • Garrido-Gracia JC, Bellido C, Aguilar R, Sanchez-Criado JE. Protein kinase C cross-talk with gonadotrope progesterone receptor is involved in GnRH-induced LH secretion. J Physiol Biochem 2006; 62:35-42.
    • (2006) J Physiol Biochem , vol.62 , pp. 35-42
    • Garrido-Gracia, J.C.1    Bellido, C.2    Aguilar, R.3    Sanchez-Criado, J.E.4
  • 15
    • 33746342151 scopus 로고    scopus 로고
    • Steroid receptor coactivator-3 is required for progesterone receptor trans-activation of target genes in response to gonadotropin-releasing hormone treatment of pituitary cells
    • An BS, Selva DM, Hammond GL, Rivero-Muller A, Rahman N, Leung PC. Steroid receptor coactivator-3 is required for progesterone receptor trans-activation of target genes in response to gonadotropin-releasing hormone treatment of pituitary cells. J Biol Chem 2006; 281:20817-20824.
    • (2006) J Biol Chem , vol.281 , pp. 20817-20824
    • An, B.S.1    Selva, D.M.2    Hammond, G.L.3    Rivero-Muller, A.4    Rahman, N.5    Leung, P.C.6
  • 17
    • 0016695106 scopus 로고
    • The effects of estrogen and progesterone on the functional capacity of the gonadotrophs
    • Lasley BL, Wang CF, Yen SS. The effects of estrogen and progesterone on the functional capacity of the gonadotrophs. J Clin Endocrinol Metab 1975; 41:820-826.
    • (1975) J Clin Endocrinol Metab , vol.41 , pp. 820-826
    • Lasley, B.L.1    Wang, C.F.2    Yen, S.S.3
  • 18
    • 0022626680 scopus 로고
    • Modification of luteinizing hormone secretion by activators of Ca2+/phospholipid-dependent protein kinase
    • Turgeon JL, Waring DW. Modification of luteinizing hormone secretion by activators of Ca2+/phospholipid-dependent protein kinase. Endocrinology 1986; 118:2053-2058.
    • (1986) Endocrinology , vol.118 , pp. 2053-2058
    • Turgeon, J.L.1    Waring, D.W.2
  • 19
    • 0026647299 scopus 로고
    • A pathway for luteinizing hormone releasinghormone self-potentiation: Cross-talk with the progesterone receptor
    • Waring DW, Turgeon JL. A pathway for luteinizing hormone releasinghormone self-potentiation: cross-talk with the progesterone receptor. Endocrinology 1992; 130:3275-3282.
    • (1992) Endocrinology , vol.130 , pp. 3275-3282
    • Waring, D.W.1    Turgeon, J.L.2
  • 20
    • 0028936101 scopus 로고
    • The self-priming effect of LHRH: A unique servomechanism and possible cellular model for memory
    • Fink G. The self-priming effect of LHRH: a unique servomechanism and possible cellular model for memory. Front Neuroendocrinol 1995; 16: 183-190.
    • (1995) Front Neuroendocrinol , vol.16 , pp. 183-190
    • Fink, G.1
  • 21
    • 0033305055 scopus 로고    scopus 로고
    • Absence of gonadotropin surges and gonadotropin-releasing hormone self-priming in ovariectomized (OVX), estrogen (E2)-treated, progesterone receptor knockout (PRKO) mice
    • Chappell PE, Schneider JS, Kim P, Xu M, Lydon JP, O'Malley BW, Levine JE. Absence of gonadotropin surges and gonadotropin-releasing hormone self-priming in ovariectomized (OVX), estrogen (E2)-treated, progesterone receptor knockout (PRKO) mice. Endocrinology 1999; 140: 3653-3658.
    • (1999) Endocrinology , vol.140 , pp. 3653-3658
    • Chappell, P.E.1    Schneider, J.S.2    Kim, P.3    Xu, M.4    Lydon, J.P.5    O'Malley, B.W.6    Levine, J.E.7
  • 22
    • 0028341166 scopus 로고
    • Activation of the progesterone receptor by the gonadotropin-releasing hormone self-priming signaling pathway
    • Turgeon JL, Waring DW. Activation of the progesterone receptor by the gonadotropin-releasing hormone self-priming signaling pathway. Mol Endocrinol 1994; 8:860-869.
    • (1994) Mol Endocrinol , vol.8 , pp. 860-869
    • Turgeon, J.L.1    Waring, D.W.2
  • 23
    • 0036185866 scopus 로고    scopus 로고
    • GnRH activates ERK1/2 leading to the induction of c-fos and LHbeta protein expression in LbetaT2 cells
    • Liu F, Austin DA, Mellon PL, Olefsky JM, Webster NJ. GnRH activates ERK1/2 leading to the induction of c-fos and LHbeta protein expression in LbetaT2 cells. Mol Endocrinol 2002; 16:419-434.
    • (2002) Mol Endocrinol , vol.16 , pp. 419-434
    • Liu, F.1    Austin, D.A.2    Mellon, P.L.3    Olefsky, J.M.4    Webster, N.J.5
  • 24
    • 0037062484 scopus 로고    scopus 로고
    • Coactivator/corepressor ratios modulate PR-mediated transcription by the selective receptor modulator RU486
    • Liu Z, Auboeuf D, Wong J, Chen JD, Tsai SY, Tsai MJ, O'Malley BW. Coactivator/corepressor ratios modulate PR-mediated transcription by the selective receptor modulator RU486. Proc Natl Acad Sci U S A 2002; 99: 7940-7944.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 7940-7944
    • Liu, Z.1    Auboeuf, D.2    Wong, J.3    Chen, J.D.4    Tsai, S.Y.5    Tsai, M.J.6    O'Malley, B.W.7
  • 25
    • 0345647105 scopus 로고    scopus 로고
    • A 361 base pair region of the rat FSH-beta promoter contains multiple progesterone receptor-binding sequences and confers progesterone responsiveness
    • O'Conner JL, Wade MF, Prendergast P, Edwards DP, Boonyaratanakornkit V, Mahesh VB. A 361 base pair region of the rat FSH-beta promoter contains multiple progesterone receptor-binding sequences and confers progesterone responsiveness. Mol Cell Endocrinol 1997; 136:67-78.
    • (1997) Mol Cell Endocrinol , vol.136 , pp. 67-78
    • O'Conner, J.L.1    Wade, M.F.2    Prendergast, P.3    Edwards, D.P.4    Boonyaratanakornkit, V.5    Mahesh, V.B.6
  • 26
    • 0026298033 scopus 로고
    • Immortalization of neuroendocrine cells by targeted oncogenesis
    • Mellon PL, Windle JJ, Weiner RI. Immortalization of neuroendocrine cells by targeted oncogenesis. Recent Prog Horm Res 1991; 47:69-96.
    • (1991) Recent Prog Horm Res , vol.47 , pp. 69-96
    • Mellon, P.L.1    Windle, J.J.2    Weiner, R.I.3
  • 27
    • 0029880964 scopus 로고    scopus 로고
    • Steroid and pulsatile gonadotropin-releasing hormone (GnRH) regulation of luteinizing hormone and GnRH receptor in a novel gonadotrope cell line
    • Turgeon JL, Kimura Y, Waring DW, Mellon PL. Steroid and pulsatile gonadotropin-releasing hormone (GnRH) regulation of luteinizing hormone and GnRH receptor in a novel gonadotrope cell line. Mol Endocrinol 1996; 10:439-450.
    • (1996) Mol Endocrinol , vol.10 , pp. 439-450
    • Turgeon, J.L.1    Kimura, Y.2    Waring, D.W.3    Mellon, P.L.4
  • 28
    • 0029846336 scopus 로고    scopus 로고
    • Immortalization of pituitary cells at discrete stages of development by directed oncogenesis in transgenic mice
    • Alarid ET, Windle JJ, Whyte DB, Mellon PL. Immortalization of pituitary cells at discrete stages of development by directed oncogenesis in transgenic mice. Development 1996; 122:3319-3329.
    • (1996) Development , vol.122 , pp. 3319-3329
    • Alarid, E.T.1    Windle, J.J.2    Whyte, D.B.3    Mellon, P.L.4
  • 30
    • 33745212905 scopus 로고    scopus 로고
    • Transcription of gonadotropin beta subunit genes involves cross-talk between the transcription factors and co-regulators that mediate actions of the regulatory hormones
    • Melamed P, Kadir MN, Wijeweera A, Seah S. Transcription of gonadotropin beta subunit genes involves cross-talk between the transcription factors and co-regulators that mediate actions of the regulatory hormones. Mol Cell Endocrinol 2006; 252:167-183.
    • (2006) Mol Cell Endocrinol , vol.252 , pp. 167-183
    • Melamed, P.1    Kadir, M.N.2    Wijeweera, A.3    Seah, S.4
  • 31
    • 0033823905 scopus 로고    scopus 로고
    • Heterogeneity of progesterone receptors A and B expression in human endometrial glands and stroma
    • Mote PA, Balleine RL, McGowan EM, Clarke CL. Heterogeneity of progesterone receptors A and B expression in human endometrial glands and stroma. Hum Reprod 2000; 15(suppl 3):48-56.
    • (2000) Hum Reprod , vol.15 , Issue.SUPPL. 3 , pp. 48-56
    • Mote, P.A.1    Balleine, R.L.2    McGowan, E.M.3    Clarke, C.L.4
  • 32
    • 0036112855 scopus 로고    scopus 로고
    • Loss of co-ordinate expression of progesterone receptors A and B is an early event in breast carcinogenesis
    • Mote PA, Bartow S, Tran N, Clarke CL. Loss of co-ordinate expression of progesterone receptors A and B is an early event in breast carcinogenesis. Breast Cancer Res Treat 2002; 72:163-172.
    • (2002) Breast Cancer Res Treat , vol.72 , pp. 163-172
    • Mote, P.A.1    Bartow, S.2    Tran, N.3    Clarke, C.L.4
  • 33
    • 0036072228 scopus 로고    scopus 로고
    • Progesterone withdrawal and estrogen activation in human parturition are coordinated by progesterone receptor A expression in the myometrium
    • Mesiano S, Chan EC, Fitter JT, Kwek K, Yeo G, Smith R. Progesterone withdrawal and estrogen activation in human parturition are coordinated by progesterone receptor A expression in the myometrium. J Clin Endocrinol Metab 2002; 87:2924-2930.
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 2924-2930
    • Mesiano, S.1    Chan, E.C.2    Fitter, J.T.3    Kwek, K.4    Yeo, G.5    Smith, R.6
  • 34
    • 0036223348 scopus 로고    scopus 로고
    • Expression of progesterone receptor isoforms A and B is differentially regulated by estrogen in different breast cancer cell lines
    • Vienonen A, Syvala H, Miettinen S, Tuohimaa P, Ylikomi T. Expression of progesterone receptor isoforms A and B is differentially regulated by estrogen in different breast cancer cell lines. J Steroid Biochem Mol Biol 2002; 80:307-313.
    • (2002) J Steroid Biochem Mol Biol , vol.80 , pp. 307-313
    • Vienonen, A.1    Syvala, H.2    Miettinen, S.3    Tuohimaa, P.4    Ylikomi, T.5
  • 35
    • 27644482809 scopus 로고    scopus 로고
    • Altered progesterone receptor isoform expression remodels progestin responsiveness of breast cancer cells
    • Graham JD, Yager ML, Hill HD, Byth K, O'Neill GM, Clarke CL. Altered progesterone receptor isoform expression remodels progestin responsiveness of breast cancer cells. Mol Endocrinol 2005; 19:2713-2735.
    • (2005) Mol Endocrinol , vol.19 , pp. 2713-2735
    • Graham, J.D.1    Yager, M.L.2    Hill, H.D.3    Byth, K.4    O'Neill, G.M.5    Clarke, C.L.6
  • 36
    • 4444284496 scopus 로고    scopus 로고
    • Reproductive tissue selective actions of progesterone receptors
    • Mulac-Jericevic B, Conneely OM. Reproductive tissue selective actions of progesterone receptors. Reproduction 2004; 128:139-146.
    • (2004) Reproduction , vol.128 , pp. 139-146
    • Mulac-Jericevic, B.1    Conneely, O.M.2
  • 37
    • 0037085303 scopus 로고    scopus 로고
    • Differential gene regulation by the two progesterone receptor isoforms in human breast cancer cells
    • Richer JK, Jacobsen BM, Manning NG, Abel MG, Wolf DM, Horwitz KB. Differential gene regulation by the two progesterone receptor isoforms in human breast cancer cells. J Biol Chem 2002; 277:5209-5218.
    • (2002) J Biol Chem , vol.277 , pp. 5209-5218
    • Richer, J.K.1    Jacobsen, B.M.2    Manning, N.G.3    Abel, M.G.4    Wolf, D.M.5    Horwitz, K.B.6
  • 38
    • 14044250986 scopus 로고    scopus 로고
    • Differential role of progesterone receptor isoforms in the transcriptional regulation of human gonadotropinreleasing hormone I (GnRH I) receptor, GnRH I, and GnRH II
    • An BS, Choi JH, Choi KC, Leung PC. Differential role of progesterone receptor isoforms in the transcriptional regulation of human gonadotropinreleasing hormone I (GnRH I) receptor, GnRH I, and GnRH II. J Clin Endocrinol Metab 2005; 90:1106-1113.
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 1106-1113
    • An, B.S.1    Choi, J.H.2    Choi, K.C.3    Leung, P.C.4
  • 39
    • 0035215296 scopus 로고    scopus 로고
    • Differential role of PR-A and -B isoforms in transcription regulation of human GnRH receptor gene
    • Cheng KW, Cheng CK, Leung PC. Differential role of PR-A and -B isoforms in transcription regulation of human GnRH receptor gene. Mol Endocrinol 2001; 15:2078-2092.
    • (2001) Mol Endocrinol , vol.15 , pp. 2078-2092
    • Cheng, K.W.1    Cheng, C.K.2    Leung, P.C.3
  • 40
    • 40849142349 scopus 로고    scopus 로고
    • Progesterone receptor (PR) isoforms PRA and PRB differentially regulate expression of the breast cancer resistance protein in human placental choriocarcinoma BeWo cells
    • Wang H, Lee EW, Zhou L, Leung PC, Ross DD, Unadkat JD, Mao Q. Progesterone receptor (PR) isoforms PRA and PRB differentially regulate expression of the breast cancer resistance protein in human placental choriocarcinoma BeWo cells. Mol Pharmacol 2008; 73:845-854.
    • (2008) Mol Pharmacol , vol.73 , pp. 845-854
    • Wang, H.1    Lee, E.W.2    Zhou, L.3    Leung, P.C.4    Ross, D.D.5    Unadkat, J.D.6    Mao, Q.7
  • 41
    • 0042693019 scopus 로고    scopus 로고
    • Defective mammary gland morphogenesis in mice lacking the progesterone receptor B isoform
    • Mulac-Jericevic B, Lydon JP, DeMayo FJ, Conneely OM. Defective mammary gland morphogenesis in mice lacking the progesterone receptor B isoform. Proc Natl Acad Sci U S A 2003; 100:9744-9749.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 9744-9749
    • Mulac-Jericevic, B.1    Lydon, J.P.2    DeMayo, F.J.3    Conneely, O.M.4
  • 42
    • 33744469042 scopus 로고    scopus 로고
    • Differential response of progesterone receptor isoforms in hormonedependent and -independent facilitation of female sexual receptivity
    • Mani SK, Reyna AM, Chen JZ, Mulac-Jericevic B, Conneely OM. Differential response of progesterone receptor isoforms in hormonedependent and -independent facilitation of female sexual receptivity. Mol Endocrinol 2006; 20:1322-1332.
    • (2006) Mol Endocrinol , vol.20 , pp. 1322-1332
    • Mani, S.K.1    Reyna, A.M.2    Chen, J.Z.3    Mulac-Jericevic, B.4    Conneely, O.M.5
  • 44
    • 54349112351 scopus 로고    scopus 로고
    • Activator protein-1 and smad proteins synergistically regulate human follicle-stimulating hormone beta-promoter activity
    • Wang Y, Fortin J, Lamba P, Bonomi M, Persani L, Roberson MS, Bernard DJ. Activator protein-1 and smad proteins synergistically regulate human follicle-stimulating hormone beta-promoter activity. Endocrinology 2008; 149:5577-5591.
    • (2008) Endocrinology , vol.149 , pp. 5577-5591
    • Wang, Y.1    Fortin, J.2    Lamba, P.3    Bonomi, M.4    Persani, L.5    Roberson, M.S.6    Bernard, D.J.7
  • 45
    • 40849142335 scopus 로고    scopus 로고
    • Synergistic induction of follicle-stimulating hormone beta-subunit gene expression by gonadal steroid hormone receptors and Smad proteins
    • Thackray VG, Mellon PL. Synergistic induction of follicle-stimulating hormone beta-subunit gene expression by gonadal steroid hormone receptors and Smad proteins. Endocrinology 2008; 149:1091-1102.
    • (2008) Endocrinology , vol.149 , pp. 1091-1102
    • Thackray, V.G.1    Mellon, P.L.2
  • 46
    • 66449126366 scopus 로고    scopus 로고
    • Progesterone inhibits basal and gonadotropin-releasing hormone induction of luteinizing hormone beta-subunit gene expression
    • Thackray VG, Hunnicutt JL, Memon AK, Ghochani Y, Mellon PL. Progesterone inhibits basal and gonadotropin-releasing hormone induction of luteinizing hormone beta-subunit gene expression. Endocrinology 2009; 150:2395-2403.
    • (2009) Endocrinology , vol.150 , pp. 2395-2403
    • Thackray, V.G.1    Hunnicutt, J.L.2    Memon, A.K.3    Ghochani, Y.4    Mellon, P.L.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.