Brain metastasis: Opportunities in basic and translational research

Cancer Research

Volumn 69, Issue 15, 2009, Pages 6015-6020

  Maher, Elizabeth A ^a   Mietz, Judy ^b   Arteaga, Carlos L ^c   DePinho, Ronald A ^d,e   Mohla, Suresh ^b  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c VANDERBILT INGRAM CANCER CENTER   (United States)

^d Belfer Institute for Innovative Cancer Science   (United States)

^e HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LAPATINIB; TRASTUZUMAB;

BASIC RESEARCH; BRAIN METASTASIS; BREAST CANCER; CANCER RADIOTHERAPY; CANCER RESEARCH; CANCER SURGERY; CLINICAL TRIAL; CONFERENCE PAPER; HUMAN; PRIORITY JOURNAL;

ANIMALS; BRAIN NEOPLASMS; HUMANS;

EID: 68049123432     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-08-4347     Document Type: Conference Paper

References (12)

1. Eichler AF, Loeffler JS. Multidisciplinary management of brain metastases. Oncologist 2007;12:884-898
2. Gaspar L, Scott C, Rotman M, et al. Recursive partitioning analysis (RPA) of prognostic factors in three Radiation Therapy Oncology Group (RTOG) brain metastases trials. Int J Radiat Oncol Biol Phys 1997;37:745-751 (Pubitemid 27181303)
3. Mehta MP, Rodrigus P, Terhaard CH, et al. Survival and neurologic outcomes in a randomized trial of motexafin gadolinium and whole-brain radiation therapy in brain metastases. J Clin Oncol 2003;21:2529-2536 (Pubitemid 46606335)
4. Shimato S, Mitsudomi T, Kosaka T, et al. EGFR mutations in patients with brain metastases from lung cancer: association with the efficacy of gefitinib. Neuro-oncol 2006;8:137-144 (Pubitemid 46542658)
5. Lin NU, Carey LA, Liu MC, et al. Phase II trial of lapatinib for brain metastases in patients with human epidermal growth factor receptor 2-positive breast cancer. J Clin Oncol 2008;26:1993-1999
6. DePinho RA. The age of cancer. Nature 2000;408:248-254
7. Chin L, Gray JW. Translating insights from the cancer genome into clinical practice. Nature 2008;452:553-563
8. Kang Y, Siegel PM, Shu W, et al. A multigenic program mediating breast cancer metastasis to bone. Cancer Cell 2003;3:537-549 (Pubitemid 36808649)
9. Minn AJ, Gupta GP, Siegel PM, et al. Genes that mediate breast cancer metastasis to lung. Nature 2005;436:518-524
10. Munoz R, Man S, Shaked Y, et al. Highly efficacious nontoxic preclinical treatment for advanced metastatic breast cancer using combination oral UFTcyclophosphamide metronomic chemotherapy. Cancer Res 2006;66:3386-3391
11. Kouros-Mehr H, Bechis SK, Slorach EM, et al. GATA-3 links tumor differentiation and dissemination in a luminal breast cancer model. Cancer Cell 2008;13:141-152 (Pubitemid 351163164)
12. Palmieri D, Bronder JL, Herring JM, et al. Her-2 overexpression increases the metastatic outgrowth of breast cancer cells in the brain. Cancer Res 2007;67:4190-4198 (Pubitemid 46815065)