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Volumn 12, Issue 2, 2005, Pages 187-193

Mesothelin-mediated targeting of adenoviral vectors for ovarian cancer gene therapy

Author keywords

Adenovirus; Dual targeting; Tissue specific promoters; Transcriptional targeting; Transductional targeting

Indexed keywords

ADENOVIRUS VECTOR; LUCIFERASE; MEMBRANE PROTEIN; MESOTHELIN MEMBRANE PROTEIN; MESSENGER RNA; PROTEIN ANTIBODY; UNCLASSIFIED DRUG;

EID: 13244298253     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3302404     Document Type: Article
Times cited : (42)

References (21)
  • 1
    • 0037260139 scopus 로고    scopus 로고
    • Cancer statistics, 2003
    • Jemal A et al. Cancer statistics, 2003. CA Cancer J Clin 2003; 53: 5-26.
    • (2003) CA Cancer J. Clin. , vol.53 , pp. 5-26
    • Jemal, A.1
  • 2
    • 0033166096 scopus 로고    scopus 로고
    • A novel tumor-specific replication-restricted adenoviral vector for gene therapy of hepatocellular carcinoma
    • Hallenbeck PL et al. A novel tumor-specific replication-restricted adenoviral vector for gene therapy of hepatocellular carcinoma. Hum Gene Ther 1999; 10: 1721-1733.
    • (1999) Hum. Gene Ther. , vol.10 , pp. 1721-1733
    • Hallenbeck, P.L.1
  • 3
    • 0030069718 scopus 로고    scopus 로고
    • Molecular cloning of mesothelin, a differentiation antigen present on mesothelium, mesotheliomas, and ovarian cancers
    • Chang K, Pastan I. Molecular cloning of mesothelin, a differentiation antigen present on mesothelium, mesotheliomas, and ovarian cancers. Proc Natl Acad Sci USA 1996; 93: 136-140.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 136-140
    • Chang, K.1    Pastan, I.2
  • 4
    • 0028330186 scopus 로고
    • Molecular cloning and expression of a cDNA encoding a protein detected by the K1 antibody from an ovarian carcinoma (OVCAR-3) cell line
    • Chang K, Pastan I. Molecular cloning and expression of a cDNA encoding a protein detected by the K1 antibody from an ovarian carcinoma (OVCAR-3) cell line. Int J Cancer 1994; 57: 90-97.
    • (1994) Int. J. Cancer , vol.57 , pp. 90-97
    • Chang, K.1    Pastan, I.2
  • 5
    • 0034084953 scopus 로고    scopus 로고
    • Structure of the mesothelin/MPF gene and characterization of its promoter
    • Urwin D, Lake RA. Structure of the mesothelin/MPF gene and characterization of its promoter. Mol Cell Biol Res Commun 2000; 3: 26-32.
    • (2000) Mol. Cell Biol. Res. Commun. , vol.3 , pp. 26-32
    • Urwin, D.1    Lake, R.A.2
  • 6
    • 0036848812 scopus 로고    scopus 로고
    • Antitumor activity of SS(dsFv)PE38 and SS1(dsFv)PE38, recombinant antimesothelin immunotoxins against human gynecologic cancers grown in organotypic culture in vitro
    • Hassan R et al. Antitumor activity of SS(dsFv)PE38 and SS1(dsFv)PE38, recombinant antimesothelin immunotoxins against human gynecologic cancers grown in organotypic culture in vitro. Clin Cancer Res 2002; 8: 3520-3526.
    • (2002) Clin. Cancer Res. , vol.8 , pp. 3520-3526
    • Hassan, R.1
  • 7
    • 0038207068 scopus 로고    scopus 로고
    • Large-scale molecular and tissue microarray analysis of mesothelin expression in common human carcinomas
    • Frierson Jr HF et al. Large-scale molecular and tissue microarray analysis of mesothelin expression in common human carcinomas. Hum Pathol 2003; 34: 605-609.
    • (2003) Hum. Pathol. , vol.34 , pp. 605-609
    • Frierson Jr., H.F.1
  • 8
    • 0034937792 scopus 로고    scopus 로고
    • An immunomagnetic-based method for the purification of ovarian cancer cells from patient-derived ascites
    • Barker SD et al. An immunomagnetic-based method for the purification of ovarian cancer cells from patient-derived ascites. Gynecol Oncol 2001; 82: 57-63.
    • (2001) Gynecol. Oncol. , vol.82 , pp. 57-63
    • Barker, S.D.1
  • 9
    • 10744220410 scopus 로고    scopus 로고
    • Gene expression patterns in ovarian carcinomas
    • Schaner ME et al. Gene expression patterns in ovarian carcinomas. Mol Biol Cell 2003; 14: 4376-4386.
    • (2003) Mol. Biol. Cell , vol.14 , pp. 4376-4386
    • Schaner, M.E.1
  • 10
    • 0034881238 scopus 로고    scopus 로고
    • Strategies to accomplish targeted expression of transgenes in ovarian cancer for molecular therapeutic applications
    • Casado E et al. Strategies to accomplish targeted expression of transgenes in ovarian cancer for molecular therapeutic applications. Clin Cancer Res 2001; 7: 2496-2504.
    • (2001) Clin. Cancer Res. , vol.7 , pp. 2496-2504
    • Casado, E.1
  • 11
    • 0035418580 scopus 로고    scopus 로고
    • Targeting oncolytic adenoviral agents to the epidermal growth factor pathway with a secretory fusion molecule
    • Hemminki A et al. Targeting oncolytic adenoviral agents to the epidermal growth factor pathway with a secretory fusion molecule. Cancer Res 2001; 61: 6377-6381.
    • (2001) Cancer Res. , vol.61 , pp. 6377-6381
    • Hemminki, A.1
  • 12
    • 0036594855 scopus 로고    scopus 로고
    • Targeted therapy against human lung cancer in nude mice by high-affinity recombinant antimesothelin single-chain Fv immunotoxin
    • Fan D et al. Targeted therapy against human lung cancer in nude mice by high-affinity recombinant antimesothelin single-chain Fv immunotoxin. Mol Cancer Ther 2002; 1: 595-600.
    • (2002) Mol. Cancer Ther. , vol.1 , pp. 595-600
    • Fan, D.1
  • 13
    • 0030982716 scopus 로고    scopus 로고
    • Cloning and expression of the recombinant FAb fragment of monoclonal antibody K1 that reacts with mesothelin present on mesotheliomas and ovarian cancers
    • Brinkmann U et al. Cloning and expression of the recombinant FAb fragment of monoclonal antibody K1 that reacts with mesothelin present on mesotheliomas and ovarian cancers. Int J Cancer 1997; 71: 638-644.
    • (1997) Int. J. Cancer , vol.71 , pp. 638-644
    • Brinkmann, U.1
  • 14
    • 0034861664 scopus 로고    scopus 로고
    • Combined transductional and transcriptional targeting improves the specificity of transgene expression in vivo
    • Reynolds PN et al. Combined transductional and transcriptional targeting improves the specificity of transgene expression in vivo. Nat Biotechnol 2001; 19: 838-842.
    • (2001) Nat. Biotechnol. , vol.19 , pp. 838-842
    • Reynolds, P.N.1
  • 15
    • 0031934438 scopus 로고    scopus 로고
    • Strategies for achieving multiple layers of selectivity in gene therapy
    • Vile RG, Sunassee K, Diaz RM. Strategies for achieving multiple layers of selectivity in gene therapy. Mol Med Today 1998; 4: 84-92.
    • (1998) Mol. Med. Today , vol.4 , pp. 84-92
    • Vile, R.G.1    Sunassee, K.2    Diaz, R.M.3
  • 16
    • 0041308272 scopus 로고    scopus 로고
    • Combined transcriptional and transductional targeting improves the specificity and efficacy of adenoviral gene delivery to ovarian carcinoma
    • Barker SD et al. Combined transcriptional and transductional targeting improves the specificity and efficacy of adenoviral gene delivery to ovarian carcinoma. Gene Therapy 2003; 10: 1198-1204.
    • (2003) Gene Therapy , vol.10 , pp. 1198-1204
    • Barker, S.D.1
  • 17
    • 0036764768 scopus 로고    scopus 로고
    • Dual targeting of adenoviral vectors at the levels of transduction and transcription enhances the specificity of gene expression in cancer cells
    • Barnett BG, Tillman BW, Curiel DT, Douglas JT. Dual targeting of adenoviral vectors at the levels of transduction and transcription enhances the specificity of gene expression in cancer cells. Mol Ther 2002; 6: 377-385.
    • (2002) Mol. Ther. , vol.6 , pp. 377-385
    • Barnett, B.G.1    Tillman, B.W.2    Curiel, D.T.3    Douglas, J.T.4
  • 18
    • 12444295422 scopus 로고    scopus 로고
    • Replication of an integrin targeted conditionally replicating adenovirus on primary ovarian cancer spheroids
    • Lam JT et al. Replication of an integrin targeted conditionally replicating adenovirus on primary ovarian cancer spheroids. Cancer Gene Ther 2003; 10: 377-387.
    • (2003) Cancer Gene Ther. , vol.10 , pp. 377-387
    • Lam, J.T.1
  • 19
    • 0036154758 scopus 로고    scopus 로고
    • Targeting adenovirus to the serotype 3 receptor increases gene transfer efficiency to ovarian cancer cells
    • Kanerva A et al. Targeting adenovirus to the serotype 3 receptor increases gene transfer efficiency to ovarian cancer cells. Clin Cancer Res 2002; 8: 275-280.
    • (2002) Clin. Cancer Res. , vol.8 , pp. 275-280
    • Kanerva, A.1
  • 20
    • 0034988243 scopus 로고    scopus 로고
    • Lung uptake of antibodies to endothelial antigens: Key determinants of vascular immunotargeting
    • Danilov SM et al. Lung uptake of antibodies to endothelial antigens: key determinants of vascular immunotargeting. Am J Physiol Lung Cell Mol Physiol 2001; 280: L1335-L1347.
    • (2001) Am. J. Physiol. Lung Cell Mol. Physiol. , vol.280
    • Danilov, S.M.1
  • 21
    • 10744228126 scopus 로고    scopus 로고
    • Targeting of adenovirus via genetic modification of the viral capsid combined with a protein bridge
    • Korokhov N et al. Targeting of adenovirus via genetic modification of the viral capsid combined with a protein bridge. J Virol 2003; 77: 12931-12940.
    • (2003) J. Virol. , vol.77 , pp. 12931-12940
    • Korokhov, N.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.