Resveratrol attenuates 1,2-dimethylhydrazine (DMH) induced glycoconjugate abnormalities during various stages of colon carcinogenesis

Phytotherapy Research

Volumn 23, Issue 8, 2009, Pages 1154-1158

  Sengottuvelan, Murugan ^a   Deeptha, Kumaraswamy ^a   Nalini, Namasivayam ^a  

^a ANNAMALAI UNIVERSITY   (India)

Author keywords

1,2 dimethylhydrazine; Adenocarcinoma; Colon carcinogenesis; Glycoconjugates; Resveratrol

Indexed keywords

1,2 DIMETHYLHYDRAZINE; FUCOSE; HEXOSAMINE; HEXOSE; RESVERATROL; SIALIC ACID;

ADENOCARCINOMA; ADENOMA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER INCIDENCE; CELL TRANSFORMATION; CHEMOPROPHYLAXIS; COLON; COLON CARCINOGENESIS; CONTROLLED STUDY; DIET; INTESTINE; LIVER LEVEL; MALE; NONHUMAN; RAT;

1,2-DIMETHYLHYDRAZINE; ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; COLONIC NEOPLASMS; DISEASE MODELS, ANIMAL; FUCOSE; GLYCOCONJUGATES; HEXOSAMINES; MALE; RATS; RATS, WISTAR; SIALIC ACIDS; STILBENES;

RATTUS;

EID: 68049101037     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.2770     Document Type: Article

References (24)

1. Alhadeff JA. 1989. Malignant cell glycoproteins and glycolipids. Crit Rev Oncol Hematol 9: 37-107.
2. Bresalier RS, Boland CR, Kim YS. 1985. Regional differences in normal and cancer associated glycoconjugates of the human colon. J Natl Cancer Inst 75: 249-260.
3. Dipple A, Michejda CJ, Weisburger EK. 1985. Metabolism of chemical carcinogens. Pharmacol Ther 27: 265-296.
4. Dische Z, Shettles LB. 1951. A new spectrophotometric test for the detection of methyl pentose. J Biol Chem 192: 579-582.
5. Donnelly LE, Newton R, Kennedy GE et al. 2004. Anti-inflammatory effects of resveratrol in lung epithelial cells: molecular mechanisms. Am J Physiol Lung Cell Mol Physiol 287: 774-783. (Pubitemid 39249390)
6. Dubois M, Gibs KA, Hamilton JK et al. 1956. Colorimetric methods for the determination of sugars and related substances. Anal Chem 28: 350-352.
7. Farber E. 1984. Cellular biochemistry of the stepwise development of cancer with chemicals: G. H. A. Clowes memorial lecture. Cancer Res 44: 5463-5474.
8. Freeman HJ, Kim Y, Kim YS. 1978. Glycoprotein metabolism in normal proximal and distal rat colon and changes associated with 1,2-dimethylhydrazine- induced colonic neoplasia. Cancer Res 38: 3385-3390. (Pubitemid 9031322)
9. Fremont L. 2000. Biological effects of resveratrol. Life Sci 66: 663-673.
10. Harvey HA, Lipton A, White D et al. 1981. Glycoproteins and human cancer: II. Correlation between circulating level and disease status. Cancer 47: 324-327.
11. Kim YS, Isaacs R. 1975. Glycoprotein metabolism in inflammatory and neoplastic diseases of the human colon. Cancer Res 35: 2092-2097.
12. Langcake P, Pryce RJ. 1976. The production of resveratrol by Vitis vinifera and other members of the Vitaceae as a response to infection or injury. Physiol Plant Pathol 9: 77-86.
13. Morse MA, Stoner GD. 1993. Cancer chemoprevention: principles and prospects. Carcinogenesis 14: 1737-1746.
14. Nalini N, Sabitha K, Viswanathan P et al. 1998. Influence of spices on the bacterial (enzyme) activity in experimental colon cancer. Med Sci Res 26: 781-784. (Pubitemid 28552219)
15. Rew DA. 1996. Heterogeneity, biodiversity and bioperversity in solid neoplasms. Eur J Surg Oncol 22: 469-473.
16. Selvendiran K, Prince Vijeya Singh J, Sakthisekaran D. 2006. In vivo effect of piperine on serum and tissue glycoprotein levels in benzo(a)pyrene induced lung carcinogenesis in Swiss albino mice. Pulm Pharmacol Ther 19: 107-111.
17. Sengottuvelan M, Viswanathan P, Nalini N. 2006. Chemopreventive effect of trans-resveratrol - a phytoalexin against colonic aberrant crypt foci and cell proliferation in 1,2-dimethylhydrazine induced colon carcinogenesis. Carcinogenesis 27: 1038-1046.
18. Spjut HJ, Noall MW. 1971. Experimental induction of tumors of the large bowel of rats. A review of the experience with 3-2′ dimethyl-4- aminobiphenyl. Cancer 28: 29-37.
19. Staudacher E, Altmann F, Wilson IB et al. 1999. Fucose in N-glycans: from plant to man. Biochim Biophys Acta 1473:216-236.
20. Tadolini B, Juliano C, Piu L et al. 2000. Resveratrol inhibition of lipid peroxidation. Free Radic Res 33: 105-114.
21. Wagner WD. 1972. More sensitive assay discriminating galactosamine and glucosamine in mixtures. Anal Biochem 94: 394-397.
22. Ward JM. 1974. Morphogenesis of chemically induced neoplasms of the colon and small intestine in rats. Lab Invest 30: 505-513.
23. Warren L. 1959. The thiobarbituric acid assay of sialic acids. J Biol Chem 234: 1971-1975.
24. Yogeeswaran G. 1983. Cell surface glycolipids and glycoproteins in malignant transformation. Adv Cancer Res 38: 289-350.