메뉴 건너뛰기




Volumn 22, Issue 2, 2009, Pages 281-288

The role of thromboelastometry and recombinant factor VIIa in trauma

Author keywords

Coagulopathy; Damage control strategy; Recombinant factor VIIa; Thromboelastometry; Trauma

Indexed keywords

FRESH FROZEN PLASMA; HEPARIN; RECOMBINANT BLOOD CLOTTING FACTOR 7A; VITAMIN K GROUP; WARFARIN;

EID: 68049094118     PISSN: 09527907     EISSN: None     Source Type: Journal    
DOI: 10.1097/ACO.0b013e328325a6be     Document Type: Review
Times cited : (24)

References (66)
  • 1
    • 0028909841 scopus 로고
    • Epidemiology of trauma deaths: A reassessment
    • Sauaia A, Moore FA. Epidemiology of trauma deaths: a reassessment. J Trauma 1995; 38:185-193.
    • (1995) J Trauma , vol.38 , pp. 185-193
    • Sauaia, A.1    Moore, F.A.2
  • 2
    • 0027966136 scopus 로고    scopus 로고
    • Hoyt DB, Bulger EM, Knudson MM. Death in the operating room: an analysis of multicenter experience. J Trauma 1994; 37:426-432.
    • Hoyt DB, Bulger EM, Knudson MM. Death in the operating room: an analysis of multicenter experience. J Trauma 1994; 37:426-432.
  • 3
    • 0033610715 scopus 로고    scopus 로고
    • Treatment of traumatic bleeding with recombinant factor VIIa
    • Kenet G, Walden R, Eldad A, Martinowitz U. Treatment of traumatic bleeding with recombinant factor VIIa. Lancet 1999; 354:1879.
    • (1999) Lancet , vol.354 , pp. 1879
    • Kenet, G.1    Walden, R.2    Eldad, A.3    Martinowitz, U.4
  • 5
    • 37349082458 scopus 로고    scopus 로고
    • Blood product replacement affects survival in patients receiving massive transfusion at a combat support hospital
    • Borgman M, Spinella PC, Perkins JG. Blood product replacement affects survival in patients receiving massive transfusion at a combat support hospital. J Trauma 2007; 63:805-813.
    • (2007) J Trauma , vol.63 , pp. 805-813
    • Borgman, M.1    Spinella, P.C.2    Perkins, J.G.3
  • 6
    • 0038801373 scopus 로고    scopus 로고
    • Acute traumatic coagulopathy
    • Brohi K. Acute traumatic coagulopathy. J Trauma 2003; 541:1127-1130.
    • (2003) J Trauma , vol.541 , pp. 1127-1130
    • Brohi, K.1
  • 7
    • 0030987123 scopus 로고    scopus 로고
    • Usefulness of thromboelastography in assessment of trauma patient coagulation
    • Kaufman CR, Dwyer KM, Crews JD, et al. Usefulness of thromboelastography in assessment of trauma patient coagulation. J Trauma 1997; 42:716-722.
    • (1997) J Trauma , vol.42 , pp. 716-722
    • Kaufman, C.R.1    Dwyer, K.M.2    Crews, J.D.3
  • 8
    • 34548851445 scopus 로고    scopus 로고
    • Early predictors of massive transfusion in combat causalities
    • Schreiber MA, Perkins J, Kiraly L, et al. Early predictors of massive transfusion in combat causalities. Am Coll Surg 2007; 205:541-545.
    • (2007) Am Coll Surg , vol.205 , pp. 541-545
    • Schreiber, M.A.1    Perkins, J.2    Kiraly, L.3
  • 9
    • 0038448077 scopus 로고    scopus 로고
    • Early coagulopathy predicts mortality in trauma
    • MaCleod JBA. Early coagulopathy predicts mortality in trauma. J Trauma 2003; 55:39-44.
    • (2003) J Trauma , vol.55 , pp. 39-44
    • MaCleod, J.B.A.1
  • 10
    • 0031750849 scopus 로고    scopus 로고
    • Hypothermic coagulopathy in trauma: Effect of varying of hypothermia on enzyme speed, platelets function and fibrinolytic activity
    • Watts DD, Trask A, Soeken F, et al. Hypothermic coagulopathy in trauma: effect of varying of hypothermia on enzyme speed, platelets function and fibrinolytic activity. J Trauma 1998; 44:846-854.
    • (1998) J Trauma , vol.44 , pp. 846-854
    • Watts, D.D.1    Trask, A.2    Soeken, F.3
  • 11
    • 0842303359 scopus 로고    scopus 로고
    • Coagulopathy in trauma patients: Etiology, recognition and therapy
    • Deloughery TG. Coagulopathy in trauma patients: etiology, recognition and therapy. Crit Care Clin 2004; 20:13-24.
    • (2004) Crit Care Clin , vol.20 , pp. 13-24
    • Deloughery, T.G.1
  • 12
    • 33845508239 scopus 로고    scopus 로고
    • The role of recombinant factor VII in neurosurgery: Hope or hype?
    • Hawryluk G, Cusimano M. The role of recombinant factor VII in neurosurgery: hope or hype? J Neurosurg 2006; 105:859-868.
    • (2006) J Neurosurg , vol.105 , pp. 859-868
    • Hawryluk, G.1    Cusimano, M.2
  • 14
    • 37349031078 scopus 로고    scopus 로고
    • Coagulopathic patients with traumatic intracranial bleeding: Defining the role of recombinant factor VIIa
    • Bartal C, Freedman J, Bowman K, Cusimano M. Coagulopathic patients with traumatic intracranial bleeding: defining the role of recombinant factor VIIa. J Trauma 2007; 63:725-732.
    • (2007) J Trauma , vol.63 , pp. 725-732
    • Bartal, C.1    Freedman, J.2    Bowman, K.3    Cusimano, M.4
  • 15
    • 0842281698 scopus 로고    scopus 로고
    • Damage control surgery
    • Schreiber MA. Damage control surgery. Crit Care Clin 2004; 20:101-111.
    • (2004) Crit Care Clin , vol.20 , pp. 101-111
    • Schreiber, M.A.1
  • 16
    • 0348163468 scopus 로고    scopus 로고
    • The effect of temperature and PH on activity of factor VIIa: Implications for the efficacy of high-dose factor VIIa in hypothermic and acidotic patients
    • Meng ZH, Wolberg AS, Monroe DM, Hofman M. The effect of temperature and PH on activity of factor VIIa: implications for the efficacy of high-dose factor VIIa in hypothermic and acidotic patients. J Trauma 2003; 55:886-891.
    • (2003) J Trauma , vol.55 , pp. 886-891
    • Meng, Z.H.1    Wolberg, A.S.2    Monroe, D.M.3    Hofman, M.4
  • 17
    • 18844483153 scopus 로고    scopus 로고
    • Treatment of critical bleeding in the future intensive care unit
    • Goodnough LT. Treatment of critical bleeding in the future intensive care unit. Intensive Care Med 2002; 28:s221.
    • (2002) Intensive Care Med , vol.28
    • Goodnough, L.T.1
  • 18
    • 0347519067 scopus 로고    scopus 로고
    • Chronic subdural hematoma: Study of 161 patients and the relationship with coagulation abnormalities
    • Yasuda CL,Morita ME, Nishimori FY, et al. Chronic subdural hematoma: study of 161 patients and the relationship with coagulation abnormalities. Arq Neurosiquitar 2003; 61:1011-1014.
    • (2003) Arq Neurosiquitar , vol.61 , pp. 1011-1014
    • Yasuda, C.L.1    Morita, M.E.2    Nishimori, F.Y.3
  • 19
    • 43449134118 scopus 로고    scopus 로고
    • Acute coagulopathy in trauma: Hypoperfusion induces anticoagulation and hyperfibrinolysis
    • Brohi K, Cohen MJ, Ganter MT, et al. Acute coagulopathy in trauma: hypoperfusion induces anticoagulation and hyperfibrinolysis. J Trauma 2008; 64:1211-1217.
    • (2008) J Trauma , vol.64 , pp. 1211-1217
    • Brohi, K.1    Cohen, M.J.2    Ganter, M.T.3
  • 20
    • 1342300762 scopus 로고    scopus 로고
    • The effect of hypertonic saline dextran on whole blood coagulation
    • Coats TJ, Heron M. The effect of hypertonic saline dextran on whole blood coagulation. Resuscitation 2004; 60:101-104.
    • (2004) Resuscitation , vol.60 , pp. 101-104
    • Coats, T.J.1    Heron, M.2
  • 21
    • 0035055647 scopus 로고    scopus 로고
    • Intravenous rFVIIa administered for hemorrhage control in hypothermic coagulopathic swine with grade V liver injuries
    • Martinowitz U, Holcomb JB, Pusateri AE, et al. Intravenous rFVIIa administered for hemorrhage control in hypothermic coagulopathic swine with grade V liver injuries. J Trauma 2001; 50:721-729.
    • (2001) J Trauma , vol.50 , pp. 721-729
    • Martinowitz, U.1    Holcomb, J.B.2    Pusateri, A.E.3
  • 22
    • 0035431030 scopus 로고    scopus 로고
    • Anemia-induced increase in bleeding time: Implications for treatment of nonsurgical blood loss
    • Valeri CR, Cassidy G, Pivacek LE, et al. Anemia-induced increase in bleeding time: implications for treatment of nonsurgical blood loss. Transfusion 2001; 41:977-983.
    • (2001) Transfusion , vol.41 , pp. 977-983
    • Valeri, C.R.1    Cassidy, G.2    Pivacek, L.E.3
  • 23
    • 0031737785 scopus 로고    scopus 로고
    • The hemostatic effect of packed red cell transfusion in patient with anemia
    • Ho CH. The hemostatic effect of packed red cell transfusion in patient with anemia. Transfusion 1998; 38:1011-1014.
    • (1998) Transfusion , vol.38 , pp. 1011-1014
    • Ho, C.H.1
  • 24
    • 43149120223 scopus 로고    scopus 로고
    • The effect of rFVIIa on mortality in combat-related causalities with severe trauma and massive transfusion
    • Spinella PC, Perkins JG, McLaughlin DF, et al. The effect of rFVIIa on mortality in combat-related causalities with severe trauma and massive transfusion. J Trauma 2008; 64:286-294.
    • (2008) J Trauma , vol.64 , pp. 286-294
    • Spinella, P.C.1    Perkins, J.G.2    McLaughlin, D.F.3
  • 25
    • 34248325280 scopus 로고    scopus 로고
    • Early versus late rFVIIa in combat trauma patients requiring massive transfusion
    • A retrospective study showing clearly that early administration of rFVIIa in civilian and combat trauma patients who are anticipated to require massive resuscitation could reduce blood requirements
    • Perkins JG, Schreiber MA, Wade CE, Holcomb JB. Early versus late rFVIIa in combat trauma patients requiring massive transfusion. J Trauma 2007; 62:1095-1101. A retrospective study showing clearly that early administration of rFVIIa in civilian and combat trauma patients who are anticipated to require massive resuscitation could reduce blood requirements.
    • (2007) J Trauma , vol.62 , pp. 1095-1101
    • Perkins, J.G.1    Schreiber, M.A.2    Wade, C.E.3    Holcomb, J.B.4
  • 26
    • 44649112504 scopus 로고    scopus 로고
    • Horton JD, Dezee KJ, Wagner M. Use of rFVIIa in trauma setting-practice patterns in United States trauma centers. Am Surg 2008; 74:413-417. Recent research providing a detailed picture about the different strategies of using factor VIIa in trauma by hospitals in the United States.
    • Horton JD, Dezee KJ, Wagner M. Use of rFVIIa in trauma setting-practice patterns in United States trauma centers. Am Surg 2008; 74:413-417. Recent research providing a detailed picture about the different strategies of using factor VIIa in trauma by hospitals in the United States.
  • 27
    • 21444452237 scopus 로고    scopus 로고
    • Guidelines for the use of recombinant activated factor VIIa in uncontrolled bleeding: A report by the Israeli Multidisciplinary rFVIIa Task Force
    • Martinowitz U, Michaelson M. Guidelines for the use of recombinant activated factor VIIa in uncontrolled bleeding: a report by the Israeli Multidisciplinary rFVIIa Task Force. J Thromb Haemost 2005; 3:640-648.
    • (2005) J Thromb Haemost , vol.3 , pp. 640-648
    • Martinowitz, U.1    Michaelson, M.2
  • 28
    • 49149105471 scopus 로고    scopus 로고
    • Damage control resuscitation: A sensible approach to the exsanguinating surgical patient
    • A current summary of the evidence supporting the damage control strategy in severe trauma patients
    • Beelkley AC. Damage control resuscitation: a sensible approach to the exsanguinating surgical patient. Crit Care Med 2008; 36:s267-s274. A current summary of the evidence supporting the damage control strategy in severe trauma patients.
    • (2008) Crit Care Med , vol.36
    • Beelkley, A.C.1
  • 29
    • 7244221863 scopus 로고    scopus 로고
    • Factor VIIa for correction of traumatic coagulopathy
    • discussion 718-719
    • Dutton RP, McCunn M, Hyder M, et al. Factor VIIa for correction of traumatic coagulopathy. J Trauma 2004; 57:709-718; discussion 718-719.
    • (2004) J Trauma , vol.57 , pp. 709-718
    • Dutton, R.P.1    McCunn, M.2    Hyder, M.3
  • 30
    • 84891966377 scopus 로고    scopus 로고
    • Point-of care coagulation monitoring: Current status of viscoelastic techniques
    • This article reviews the basic principles and properties of TEG and ROTEM and their clinical uses
    • Ganter MT, Hofer CK. Point-of care coagulation monitoring: current status of viscoelastic techniques. Yearb Intensive Care Emerg Med 2007; 835-846. This article reviews the basic principles and properties of TEG and ROTEM and their clinical uses.
    • (2007) Yearb Intensive Care Emerg Med , pp. 835-846
    • Ganter, M.T.1    Hofer, C.K.2
  • 31
    • 34547905714 scopus 로고    scopus 로고
    • Management of massive operative blood loss
    • This article summarizes the pathophysiology of blood loss and impending coagulation disorders, the relative inferiority of routine coagulation tests and the various components of TEG/ROTEM
    • Kozek-Langenecker S. Management of massive operative blood loss. Minerva Anestesiologica 2007; 73:401-415. This article summarizes the pathophysiology of blood loss and impending coagulation disorders, the relative inferiority of routine coagulation tests and the various components of TEG/ROTEM.
    • (2007) Minerva Anestesiologica , vol.73 , pp. 401-415
    • Kozek-Langenecker, S.1
  • 32
    • 61649106091 scopus 로고    scopus 로고
    • Monitoring hemostasis in emergency medicine
    • This article proposes, for the first time, a reasonable ROTEM-dependent algorithm for the treatment of trauma victims
    • Kozek-Langenecker S. Monitoring hemostasis in emergency medicine. Yearb Intensive Care Emerg Med 2007; 848-859. This article proposes, for the first time, a reasonable ROTEM-dependent algorithm for the treatment of trauma victims.
    • (2007) Yearb Intensive Care Emerg Med , pp. 848-859
    • Kozek-Langenecker, S.1
  • 33
    • 33846423913 scopus 로고    scopus 로고
    • Diagnosis of early coagulation abnormalities in trauma patients by rotational thromboelastography
    • This is the first prospective observational study that assessed and proposed the use of ROTEM as a guiding tool for transfusion
    • Rugeri L, Levrat A, David JS, et al. Diagnosis of early coagulation abnormalities in trauma patients by rotational thromboelastography. J Thromb Haemost 2007; 5:289-295. This is the first prospective observational study that assessed and proposed the use of ROTEM as a guiding tool for transfusion.
    • (2007) J Thromb Haemost , vol.5 , pp. 289-295
    • Rugeri, L.1    Levrat, A.2    David, J.S.3
  • 34
    • 44649109632 scopus 로고    scopus 로고
    • Evaluation of rotation thromboelastography for the diagnosis of hyperfibrinolysis in trauma patients
    • This study proved ROTEM to be a rapid and accurate tool for the early detection of hyperfibrinolysis in trauma patients
    • Levrat A, Gros A, Rugeri L. Evaluation of rotation thromboelastography for the diagnosis of hyperfibrinolysis in trauma patients. Br J Anaesth 2008; 100:792-797. This study proved ROTEM to be a rapid and accurate tool for the early detection of hyperfibrinolysis in trauma patients.
    • (2008) Br J Anaesth , vol.100 , pp. 792-797
    • Levrat, A.1    Gros, A.2    Rugeri, L.3
  • 35
    • 30044438890 scopus 로고    scopus 로고
    • The emerging role of recombinant activated FVIIa in the treatment of blunt traumatic hemorrhage
    • Rizoli SB, Chughtai T. The emerging role of recombinant activated FVIIa in the treatment of blunt traumatic hemorrhage. Expert Opin Biol Ther 2006; 6:73-81.
    • (2006) Expert Opin Biol Ther , vol.6 , pp. 73-81
    • Rizoli, S.B.1    Chughtai, T.2
  • 36
    • 18144393811 scopus 로고    scopus 로고
    • Use of activated factor VIIa in patients undergoing reconstruction surgery for traumatic fracture of pelvis or pelvis and acetabulum, a double blind randomized placebo-controlled trial
    • Raobaikady R, Redman J, Ball JA, et al. Use of activated factor VIIa in patients undergoing reconstruction surgery for traumatic fracture of pelvis or pelvis and acetabulum, a double blind randomized placebo-controlled trial. Br J Anesth 2005; 94:586-591.
    • (2005) Br J Anesth , vol.94 , pp. 586-591
    • Raobaikady, R.1    Redman, J.2    Ball, J.A.3
  • 37
    • 33845790028 scopus 로고    scopus 로고
    • Recombinant activated coagulation factor VII and bleeding trauma patients
    • Rizoli SB, Nascimento B, Osman F, et al. Recombinant activated coagulation factor VII and bleeding trauma patients. J Trauma 2006; 61:1419-1425.
    • (2006) J Trauma , vol.61 , pp. 1419-1425
    • Rizoli, S.B.1    Nascimento, B.2    Osman, F.3
  • 38
    • 43149120223 scopus 로고    scopus 로고
    • The effect of rFVIIa on mortality in combat-related causalities with severe trauma and massive transfusion
    • The first retrospective cohort study in combat trauma patients showing improved mortality rate by using rFVIIa in severe trauma patients
    • Spinella PC, Perkins JG, McLaughlin DF, et al. The effect of rFVIIa on mortality in combat-related causalities with severe trauma and massive transfusion. J Trauma 2008; 64:286-294. The first retrospective cohort study in combat trauma patients showing improved mortality rate by using rFVIIa in severe trauma patients.
    • (2008) J Trauma , vol.64 , pp. 286-294
    • Spinella, P.C.1    Perkins, J.G.2    McLaughlin, D.F.3
  • 39
    • 53049093520 scopus 로고    scopus 로고
    • Efficacy of red blood cell transfusion in the critically ill: A systematic review of the literature
    • Marik PE, Crowin HL. Efficacy of red blood cell transfusion in the critically ill: a systematic review of the literature. Crit Care Med 2008; 36:2667-2674.
    • (2008) Crit Care Med , vol.36 , pp. 2667-2674
    • Marik, P.E.1    Crowin, H.L.2
  • 40
    • 50949084274 scopus 로고    scopus 로고
    • Effect of haemodilution, acidosis, and hypothermia on the activity of recombinant fVIIa (Novoseven)
    • Viuff D, Lauritzizen B, Pusateri AH, et al. Effect of haemodilution, acidosis, and hypothermia on the activity of recombinant fVIIa (Novoseven). Br J Anaesth 2008; 101:324-331.
    • (2008) Br J Anaesth , vol.101 , pp. 324-331
    • Viuff, D.1    Lauritzizen, B.2    Pusateri, A.H.3
  • 41
    • 0348163468 scopus 로고    scopus 로고
    • The effect of temperature and pH on the activity of factor VIIa: Implications for the efficacy of high dose factor in hypothermic and acidotic patients
    • Meng ZH, Wolberg AS, Monroe DM, Hoffman M. The effect of temperature and pH on the activity of factor VIIa: implications for the efficacy of high dose factor in hypothermic and acidotic patients. J Trauma 2003; 55:886-891.
    • (2003) J Trauma , vol.55 , pp. 886-891
    • Meng, Z.H.1    Wolberg, A.S.2    Monroe, D.M.3    Hoffman, M.4
  • 42
    • 36048934606 scopus 로고    scopus 로고
    • In vitro effect of activated recombinant factor VIIa on coagulation properties of human blood at hypothermic temperatures
    • Kheirabadi BS, Delgado AV, Dubick MA, et al. In vitro effect of activated recombinant factor VIIa on coagulation properties of human blood at hypothermic temperatures. J Trauma 2007; 63:1079-1086.
    • (2007) J Trauma , vol.63 , pp. 1079-1086
    • Kheirabadi, B.S.1    Delgado, A.V.2    Dubick, M.A.3
  • 43
    • 29544449813 scopus 로고    scopus 로고
    • Determinants of futility of administration of recombinant factor VIIa
    • Stein DM, Dutton RP, O'Connor J, et al. Determinants of futility of administration of recombinant factor VIIa. J Trauma 2005; 59:609-615.
    • (2005) J Trauma , vol.59 , pp. 609-615
    • Stein, D.M.1    Dutton, R.P.2    O'Connor, J.3
  • 44
    • 36048934606 scopus 로고    scopus 로고
    • In vitro effect of activated recombinant FVIIa on coagulation properties of human blood at hypothermic temperatures
    • Kheirabadi RS, Delgado AV, Dubick MA. In vitro effect of activated recombinant FVIIa on coagulation properties of human blood at hypothermic temperatures. J Trauma 2007; 63:1079-1086.
    • (2007) J Trauma , vol.63 , pp. 1079-1086
    • Kheirabadi, R.S.1    Delgado, A.V.2    Dubick, M.A.3
  • 45
    • 0036124540 scopus 로고    scopus 로고
    • Comparative study of traumatic and spontaneous intracerebral hemorrhage
    • Siddique MS, Gregson BA, Fernades HM, et al. Comparative study of traumatic and spontaneous intracerebral hemorrhage. J Neurosurg 2002; 96:86-89.
    • (2002) J Neurosurg , vol.96 , pp. 86-89
    • Siddique, M.S.1    Gregson, B.A.2    Fernades, H.M.3
  • 46
    • 24644491444 scopus 로고    scopus 로고
    • Recombinant factor VII as adjuvant therapy for bleeding control in severely injured trauma patients: Two parallel randomized, placebo-controlled, double blind clinical trials
    • Boffard KD, Riou B, Warren B. Recombinant factor VII as adjuvant therapy for bleeding control in severely injured trauma patients: two parallel randomized, placebo-controlled, double blind clinical trials. J Trauma 2005; 59:8-15.
    • (2005) J Trauma , vol.59 , pp. 8-15
    • Boffard, K.D.1    Riou, B.2    Warren, B.3
  • 47
    • 13844315293 scopus 로고    scopus 로고
    • Recombinant activated factor VII intracerebral hemorrhage trial investigators: Recombinant activated factor VII for acute intracerebral hemorrhage
    • Mayer SA, Brun NC, Begtrup K, et al. Recombinant activated factor VII intracerebral hemorrhage trial investigators: recombinant activated factor VII for acute intracerebral hemorrhage. N Engl J Med 2005; 352:777-785.
    • (2005) N Engl J Med , vol.352 , pp. 777-785
    • Mayer, S.A.1    Brun, N.C.2    Begtrup, K.3
  • 48
    • 0036345150 scopus 로고    scopus 로고
    • Management of severe head injury: Institutional variations in care and effect on outcome
    • Bugler E, Nathens A, Rivara F. Management of severe head injury: institutional variations in care and effect on outcome. Crit Care Med 2002; 30:1870-1876.
    • (2002) Crit Care Med , vol.30 , pp. 1870-1876
    • Bugler, E.1    Nathens, A.2    Rivara, F.3
  • 49
    • 85052610397 scopus 로고    scopus 로고
    • Mortality from traumatic brain injury
    • Lu J,Marmarou A, Choi S. Mortality from traumatic brain injury. Acta Neurochir 2005; 95:s281-s285.
    • (2005) Acta Neurochir , vol.95
    • Lu, J.1    Marmarou, A.2    Choi, S.3
  • 50
    • 24644480580 scopus 로고    scopus 로고
    • Coagulopathy in traumatic brain injury
    • Stein SC, Smith DH. Coagulopathy in traumatic brain injury. Neurocrit Care 2004; 1:479-488.
    • (2004) Neurocrit Care , vol.1 , pp. 479-488
    • Stein, S.C.1    Smith, D.H.2
  • 51
    • 14944366530 scopus 로고    scopus 로고
    • Nonneurologic organ dysfunction in severe traumatic brain injury
    • Zygun DA, Kortbeek JB, Fick GH, et al. Nonneurologic organ dysfunction in severe traumatic brain injury. Crit Care Med 2005; 33:654-660.
    • (2005) Crit Care Med , vol.33 , pp. 654-660
    • Zygun, D.A.1    Kortbeek, J.B.2    Fick, G.H.3
  • 52
    • 11144246729 scopus 로고    scopus 로고
    • Safety and feasibility of recombinant factor VIIa for acute intracerebral hemorrhage
    • Mayer SA, Burn NC, Broderick J, et al. Safety and feasibility of recombinant factor VIIa for acute intracerebral hemorrhage. Stroke 2005; 36:74-79.
    • (2005) Stroke , vol.36 , pp. 74-79
    • Mayer, S.A.1    Burn, N.C.2    Broderick, J.3
  • 53
    • 0037229469 scopus 로고    scopus 로고
    • Ultra-early hemostatic therapy for intracerebral hemorrhage
    • Mayer SA. Ultra-early hemostatic therapy for intracerebral hemorrhage. Stroke 2003; 34:224-229.
    • (2003) Stroke , vol.34 , pp. 224-229
    • Mayer, S.A.1
  • 54
    • 43549087410 scopus 로고    scopus 로고
    • Efficacy and safety of recombinant activated factor VII for acute intracerebral hemorrhage
    • The phase III study showing contrast and less encouraging results than previous studies showed
    • Mayer SA, Brun NC, Bergtrup K, et al. Efficacy and safety of recombinant activated factor VII for acute intracerebral hemorrhage. N Engl J Med 2008; 358:2127-2137. The phase III study showing contrast and less encouraging results than previous studies showed.
    • (2008) N Engl J Med , vol.358 , pp. 2127-2137
    • Mayer, S.A.1    Brun, N.C.2    Bergtrup, K.3
  • 55
    • 0038386893 scopus 로고    scopus 로고
    • Recombinant activated factor VII for the rapid correction of coagulopathy in nonhemophilic neurosurgical patients
    • Park P, Fewel ME, Garton HJ. Recombinant activated factor VII for the rapid correction of coagulopathy in nonhemophilic neurosurgical patients. Neurosurgery 2003; 53:34-39.
    • (2003) Neurosurgery , vol.53 , pp. 34-39
    • Park, P.1    Fewel, M.E.2    Garton, H.J.3
  • 56
    • 33751188949 scopus 로고    scopus 로고
    • The use of recombinant factor VIIa (Novoseven) for treatment of active or impending bleeding in brain injury: Broadening the indications
    • Yusin Y, Perel A, Berkenstadt H, et al. The use of recombinant factor VIIa (Novoseven) for treatment of active or impending bleeding in brain injury: broadening the indications. J Clin Anesth 2006; 18:545-551.
    • (2006) J Clin Anesth , vol.18 , pp. 545-551
    • Yusin, Y.1    Perel, A.2    Berkenstadt, H.3
  • 57
    • 48949119534 scopus 로고    scopus 로고
    • rVIIa Traumatic ICH Study Group. Recombinant factor VIIa in traumatic intracerebral hemorrhage: Results of a dose escalation clinical trial
    • The first prospective randomized control-dose escalation study of rFVIIa in traumatic ICH patients
    • Narayan RK, Mass AIR, Marshall LF, et al., rVIIa Traumatic ICH Study Group. Recombinant factor VIIa in traumatic intracerebral hemorrhage: results of a dose escalation clinical trial. Neurosurgery 2008; 62:776-788. The first prospective randomized control-dose escalation study of rFVIIa in traumatic ICH patients.
    • (2008) Neurosurgery , vol.62 , pp. 776-788
    • Narayan, R.K.1    Mass, A.I.R.2    Marshall, L.F.3
  • 58
    • 0036962116 scopus 로고    scopus 로고
    • Recombinant coagulation factor VIIa for rapid preoperative correction of warfarin related coagulopathy in patients with acute subdural hematoma
    • Veshchev I, Elran H, Salame K. Recombinant coagulation factor VIIa for rapid preoperative correction of warfarin related coagulopathy in patients with acute subdural hematoma. Med Sci Monit 2002; 8:98-100.
    • (2002) Med Sci Monit , vol.8 , pp. 98-100
    • Veshchev, I.1    Elran, H.2    Salame, K.3
  • 59
    • 40549135630 scopus 로고    scopus 로고
    • Recombinant factor VIIa: Decreasing time to intervention in coagulopathic patients with severe traumatic brain injury
    • A well designed retrospective study using endpoint-directed therapy to support the controversial indication of rFVIIa in TBI
    • Stein DM, Dutton RP, Kramer ME, et al. Recombinant factor VIIa: decreasing time to intervention in coagulopathic patients with severe traumatic brain injury. J Trauma 2008; 64:620-628. A well designed retrospective study using endpoint-directed therapy to support the controversial indication of rFVIIa in TBI.
    • (2008) J Trauma , vol.64 , pp. 620-628
    • Stein, D.M.1    Dutton, R.P.2    Kramer, M.E.3
  • 60
    • 0028902385 scopus 로고
    • Intracranial traumatic and nontraumatic hemorrhagic complications of warfarin treatment
    • Matheisen T, Benedikrsdonir K, Linquist M, Von Holst H. Intracranial traumatic and nontraumatic hemorrhagic complications of warfarin treatment. Acta Neurol Scand 1995; 91:208-214.
    • (1995) Acta Neurol Scand , vol.91 , pp. 208-214
    • Matheisen, T.1    Benedikrsdonir, K.2    Linquist, M.3    Von Holst, H.4
  • 61
    • 34547759327 scopus 로고    scopus 로고
    • Guidelines for the management of severe traumatic brain injury
    • Brain Traumatic Foundation and AANS/CNS Joint section on neurotrauma and critical care
    • Brain Traumatic Foundation and AANS/CNS Joint section on neurotrauma and critical care. Guidelines for the management of severe traumatic brain injury. J Neurotrauma 2007; 24(Suppl):s1-s106.
    • (2007) J Neurotrauma , vol.24 , Issue.SUPPL.
  • 62
    • 33749674311 scopus 로고    scopus 로고
    • Uncontrollable bleeding in a patient with head trauma treated with blood component therapy guided by thromboelastography
    • Hansen MK, Jensen MK, Andersen C. Uncontrollable bleeding in a patient with head trauma treated with blood component therapy guided by thromboelastography. Ugeskr Laegr 2006; 168:3535-3536.
    • (2006) Ugeskr Laegr , vol.168 , pp. 3535-3536
    • Hansen, M.K.1    Jensen, M.K.2    Andersen, C.3
  • 64
    • 49949112567 scopus 로고    scopus 로고
    • Thromboelastographyguided rVIIa administration in a patient with refractory autoimmune idiopathic thrombocytopenia
    • James KMH, Melikian CN, Chowdary P, Mallett SV. Thromboelastographyguided rVIIa administration in a patient with refractory autoimmune idiopathic thrombocytopenia. Anesth Analg 2008; 107:402-405.
    • (2008) Anesth Analg , vol.107 , pp. 402-405
    • James, K.M.H.1    Melikian, C.N.2    Chowdary, P.3    Mallett, S.V.4
  • 65
    • 34548361909 scopus 로고    scopus 로고
    • rVIIa effectively reverses the anticoagulant effects of heparin, enoxaparin, fondaparinux, argatroban, and bivalirudin ex vivo as measured using thromboelastography
    • Young G, Yonekawa KE, Nekagawa PA, et al. rVIIa effectively reverses the anticoagulant effects of heparin, enoxaparin, fondaparinux, argatroban, and bivalirudin ex vivo as measured using thromboelastography. Blood Coagul Fibrinolysis 2007; 18:547-553.
    • (2007) Blood Coagul Fibrinolysis , vol.18 , pp. 547-553
    • Young, G.1    Yonekawa, K.E.2    Nekagawa, P.A.3
  • 66
    • 0037268928 scopus 로고    scopus 로고
    • New insights into the coagulation system and implication for new therapeutic options with recombinant factor VIIa
    • Veldman A, Hoffman M, Ehrenforth S. New insights into the coagulation system and implication for new therapeutic options with recombinant factor VIIa. Curr Med Chem 2003; 10:797-811.
    • (2003) Curr Med Chem , vol.10 , pp. 797-811
    • Veldman, A.1    Hoffman, M.2    Ehrenforth, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.