Platelet-rich plasma improves healing of tympanic membrane perforations: Experimental study

Journal of Laryngology and Otology

Volumn 123, Issue 5, 2009, Pages 482-487

  Erkilet, E ^a   Koyuncu, M ^a   Atmaca, S ^a   Yarim, M ^a  

^a ONDOKUZ MAYIS UNIVERSITY   (Turkey)

Author keywords

Otologic surgical procedures; Platelet rich plasma; Rat; Tympanic membrane perforations

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EARDRUM PERFORATION; HISTOPATHOLOGY; MICROSCOPY; NONHUMAN; RAT; THROMBOCYTE RICH PLASMA; TREATMENT OUTCOME; WOUND HEALING;

ANIMALS; DISEASE MODELS, ANIMAL; PLATELET-RICH PLASMA; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; REGENERATION; STATISTICS AS TOPIC; TYMPANIC MEMBRANE; TYMPANIC MEMBRANE PERFORATION; WOUND HEALING;

EID: 68049092051     PISSN: 00222151     EISSN: 17485460     Source Type: Journal    
DOI: 10.1017/S0022215108003848     Document Type: Article

References (27)

1. Guneri EA, Tekin S, Yilmaz O, Ozkara E, Erdag TE, Ikiz AO et al. The effects of hyaluronic acid, epidermal growth factor, and mitomycin in an experimental model of acute traumatic tympanic membrane perforation. Otol Neurotol 2003;24:371-6
2. Kaftan H, Herzog M, Miehe B, Hosemann W. Topical application of transforming growth factor-beta 1 in acute traumatic tympanic membrane perforations: an experimental study in rats. Wound Repair Regen 2006;14:453-6
3. Ozturk K, Yaman H, Cihat AM, Arbag H, Keles B, Uyar Y. Effectiveness of MeroGel hyaluronic acid on tympanic membrane perforations. Acta Otolaryngol 2006;126: 1158-63
4. Yeo SW, Kim SW, Suh BD, Cho SH. Effects of platelet-derived growth factor-AA on the healing process of tympanic membrane perforation. Am J Otolaryngol 2000; 21:153-60
5. Ramalho JR, Bento RF. Healing of subacute tympanic membrane perforations in chinchillas treated with epidermal growth factor and pentoxifylline. Otol Neurotol 2006; 27:720-7
6. Somers T, Goovaerts G, Schelfhout L, Peeters S, Govaerts PJ, Offeciers E. Growth factors in tympanic membrane perforations. Am J Otol 1998;19:428-34
7. Boyapati L, Wang HL. The role of platelet-rich plasma in sinus augmentation: a critical review. Implant Dent 2006; 15:160-70
8. Eppley BL, Pietrzak WS, Blanton M. Platelet-rich plasma: a review of biology and applications in plastic surgery. Plast Reconstr Surg 2006;118:147-59
9. Everts PA, Mahoney CB, Hoffmann JJ, Schönberger JP, Box HA, Zundert AV et al. Platelet-rich plasma preparation using three devices: implications for platelet activation and platelet growth factor release. Growth Factors 2006;24:165-71
10. Floryan KM, Berghoff WJ. Intraoperative use of autologous platelet-rich and platelet-poor plasma for orthopedic surgery patients. AORN J 2004;80:668-74
11. Grageda E. Platelet-rich plasma and bone graftmaterials: a review and a standardized research protocol. Implant Dent 2004;13:301-9
12. Pietrzak WS, Eppley BL. Platelet rich plasma: biology and new technology. J Craniofac Surg 2005;16:1043-54
13. Lambert PR, McElveen JT. Tympanoplastic surgery for chronic ear disease. In: Cummings CW, Fredrickson JM, Harker LA, Krause CJ, Richardson MA, Schuller DE, eds. Otolaryngology Head and Neck Surgery, 3rd ed. St Louis: Mosby-Year Book, 1998;3108-17
14. Govaerts PJ, Jacob WA, Marquet J. Histological study of the thin replacement membrane of human tympanic membrane perforations. Acta Otolaryngol 1988;105:297-302
15. Hellstrom S, Laurent C. Hyaluronan and healing of tympanic membrane perforations. An experimental study. Acta Otolaryngol 1987;442:54-61
16. Johnson A, Hawke M. An ultrastructural study of the skin of the tympanic membrane and external ear canal of the guinea pig. J Otolaryngol 1985;14:357-64
17. Ma Y, Zhao H, Zhou X. Topical treatment with growth factors for tympanic membrane perforations: progress towards clinical application. Acta Otolaryngol 2002;122: 586-99
18. Gladstone HB, Jackler RK, Varav K. Tympanic membrane wound healing. Otolaryngol Clin North Am 1995;28:913-32
19. Hom DB. Growth factors and wound healing in otolaryngology. Otolaryngol Head Neck Surg 1994;110:560-4
20. Mondain M, Ryan A. Epidermal growth factor and basic fibroblast growth factor are induced in guinea-pig tympanic membrane following traumatic perforation. Acta Otolaryngol 1995;115:50-4
21. O'Daniel TG, Petitjean M, Jones SC. Epidermal growth factor binding and action on tympanic membranes. Ann Otol Rhinol Laryngol 1990;99:80-4
22. Marx RE, Carlson ER, Eichstaedt RM, Schimmele SR, Strauss JE, Georgeff KR. Platelet-rich plasma: growth factor enhancement for bone grafts. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1998;85:638-46
23. Anitua E. Plasma rich in growth factors: preliminary results of use in the preparation of future sites for implants. Int J Oral Maxillofac Implants 1999;14:529-35
24. Kim SG, Chung CH, Kim YK, Park JC, Lim SC. Use of particulate dentin-plaster of Paris combination with/ without platelet-rich plasma in the treatment of bone defects around implants. Int J Oral Maxillofac Implants 2002;17:86-94
25. Dere H, Unal A, Ozcan I, Yrdimci S, Ergul G, Titiz A et al. Histological evaluation of basic fibroblast growth factor effect on the healing of traumatic tympanic membrane perforation [in Turkish]. Turk Otolarengoloji Arsivi 1997;35: 33-7
26. Mondain M, Saffiedine S, Uziel A. Fibroblast growth factor improves the healing of experimental tympanic membrane perforations. Acta Otolaryngol 1991;111:337-41
27. Fina M, Baird A, Ryan A. Direct application of basic fibroblast growth factor improves tympanic membrane perforation healing. Laryngoscope 1993;103:804-9