Application of organic mono-phase and organic - Aqueous two-liquid-phase systems in microalgal conversion of androst-4-en-3,17-dione by Nostoc muscorum

Biocatalysis and Biotransformation

Volumn 27, Issue 3, 2009, Pages 219-225

  Arabi, Homeira ^a   Yazdi, Mojtaba Tabatabaei ^a   Faramarzi, Mohammad Ali ^a  

^a TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Androst 4 en 3,17 dione; Bioconversion; Microalgae; Nostoc muscorum; Organic aqueous solvent system

Indexed keywords

ALGAL CELLS; ANDROST-4-EN-3,17-DIONE; AQUEOUS TWO PHASE SYSTEM; BIPHASIC SYSTEMS; CARBONYL REDUCTION; HEXADECANE; MICROALGA; MICROALGAE; NOSTOC MUSCORUM; ORGANIC-AQUEOUS SOLVENT SYSTEM; PARTITION COEFFICIENT; PHASE RATIOS; REACTION TEMPERATURE; SUBSTRATE CONCENTRATIONS; TETRADECANE; TWO-LIQUID-PHASE SYSTEMS; WHOLE CELL;

ALCOHOLS; ALGAE; ALGEBRA; BIOCOMPATIBILITY; MICROORGANISMS; ORGANIC SOLVENTS; PARAFFINS;

BIOCONVERSION;

ANDROSTENEDIONE; HEXADECANE; OCTANOL; ORGANIC SOLVENT; TESTOSTERONE; TETRADECANE; WATER;

AQUEOUS SOLUTION; ARTICLE; BIOCATALYST; BIOCOMPATIBILITY; BIOTRANSFORMATION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG STRUCTURE; DRUG SYNTHESIS; HYDROPHOBICITY; NONHUMAN; NOSTOC MUSCORUM; PROCESS OPTIMIZATION; TEMPERATURE;

ALGAE; NOSTOC MUSCORUM; NOSTOCACEAE;

EID: 68049089730     PISSN: 10242422     EISSN: 10292446     Source Type: Journal    
DOI: 10.1080/10242420902890018     Document Type: Article

References (32)

1. Ahmad S, Johri BN. 1993. Microbial transformation of sterol in organic media. Indian J Chem 32:67-69.
2. Angelova B, Schmauder HP. 1999. Lipophilic compounds in biotechnology - interactions with cells and technological problems. J Biotechnol 67:13-32.
3. Angelova B, Fernandes P, Cruz A, Pinheiro HM, Mutafov S, Cabral JMS. 2005. Hydroxylation of androstenedione by resting Rhodococcus sp. cells in organic media. Enzyme Microb Technol 37:718-722.
4. Boggess FS, Naylor A. 1975. Partial purification and properties of ornithine transcarbamoylase from Nostoc muscorum Kutzing. Plant Physiol 56:640-644.
5. Borowitzka MA. 1988. Algal growth media and sources of algal cultures. In: Borowitzka MA, Borowitzka LJ, editors. Microalgal biotechnology. Cambridge: Cambridge University Press. p 456-465.
6. Cabral JMS, Aires-Barros MR, Pinheiro H, Prazeres DMF. 1997. Biotransformation in organic media by enzymes and whole cells. J Biotechnol 59:133-143.
7. Carmichael WW. 1997. The cyanotoxins. In: Callow JA, editor. Advances in botanical research. London: Academic Press. p. 211-256.
8. Choi KO, Song SH, Yoo YJ. 2004. Permeabilization of Ochrobactrum anthropi SY509 cells with organic solvents for whole cell biocatalyst. Biotechnol Bioprocess Eng 9:147-150.
9. Cruz A, Fernandes P, Cabral JMS, Pinheiro HM. 2001. Whole-cell bioconversion of b-sitosterol in aqueous-organic two-phase systems. J Mol Catal B Enzym 11:579-585.
10. Cruz A, Fernandes P, Cabral JMS, Pinheiro HM. 2004. Solvent partitioning and whole-cell sitosterol bioconversion activity in aqueous-organic two-phase systems. Enzyme Microb Technol 34:342-353.
11. De Bont J. 1998. Solvent tolerant bacteria in biocatalysis. TIBTECH 16:493-499.
12. Dembitsky VM, Rezanka T. 2005. Metabolites produced by nitrogen-fixing Nostoc species. Folia Microbiol 50:363-391.
13. Dias ACP, Cabral JMS, Pinheiro HM. 1994. Sterol side-chain cleavage with immobilized mycobacterium cells in waterimmiscible organic solvents. Enzyme Microb Technol 16:708-714.
14. El-Sheekh M, Osman MEH, Dyab MA, Amer MS. 2006. Production and characterization of antimicrobial active substance from the cyanobacterium Nostoc muscorum. Environ Toxicol Pharmacol 21:42-50.
15. Faramarzi MA, Tabatabaei Yazdi M, Ghostinroudi H, Amini M, Ghasemi Y, Jahandar H, Arabi H. 2006. Nostoc muscorum: A regioselective biocatalyst for 17-carbonyl reduction of androst-4-en-3,17-dione and androst-1,4-dien-3,17-dione. Ann Microbiol 56:255-258.
16. Faramarzi MA, Adrangi S, Tabatabaei Yazdi M. 2008. Microalgal biotransformation of steroids. J Phycol 44:27-37.
17. Fernandes P, Cabral JMS, Pinheiro HM. 1995. Bioconversion of a hydrocortisone derivative in an organic-aqueous twoliquid- phase system. Enzyme Microb Technol 17:163-167.
18. Fleming H, Haselkorn R. 1973. Differentiation in Nostoc muscorum: nitrogenase is synthesized in heterocysts. Proc Natl Acad Sci U S A 70:2727-2731.
19. Flores MV, Voget CE, Ertola RJJ. 1994. Permeabilization of yeast cells (Kluyveromyces lactis) with organic solvents. Enzyme Microb Technol 16:340-346.
20. Gendel SM, Nohr RS. 1989. Growth and nitrogen fixation by immobilized cyanobacteria. Appl Microbiol Biotechnol 31:138-145.
21. Han J, McCarrth ED, Calvin M. 1968. Hydrocarbon constituents of the blue-green algae Nostoc muscorum, Anacystis nidulans, Phormidium luridum and Clorogloea fritschii. J Chem Soc C 2785-2791.
22. Katircioglu H, Akin BS, Atici T. 2004. Microalgal toxin(s): characteristics and importance. Afr J Biotechnol 3:667-674.
23. Laane C, Boeren S, Vos K. 1985. On optimizing organic solvent in multi-liquid-phase biocatalysis. Trends Biotechnol 3:251-252.
24. Leon R, Garbayo N, Hernandez A, Vigara J, Vilchez C. 2001. Organic solvent toxicity in photoautotrophic unicellular microorganisms. Enzyme Microb Technol 29:173-180.
25. Liu WH, Horng WC, Tsai MS. 1996. Bioconversion of cholesterol to cholest-4-en-one in aqueous/organic solvent two-phase reactors. Enzyme Microb Technol 18:184-189.
26. Potts N, Olie JJ, Nickels JS, Parasons J, White DC. 1987. Variation in phospholipids ester-linked fatty acids and carotenoids of desiccated Nostoc commune (cyanobacteria) from different geographic location. Appl Environ Microbiol 53:4-9.
27. Songtao B, Lianxiang D, Liming Z, Fuping L. 2005. Bioconversion of methyl testosterone in a biphasic system. Process Biochem 40:3309-3313.
28. Stark D, Van Stockar U. 2003. In situ production removal (ISPR) in whole cell biotechnology during the last twenty years. Adv Biochem Eng Biotechnol 80:149-157.
29. Tabatabaei Yazdi M, Arabi H, Faramarzi MA, Ghasemi Y, Amini M, Shokravi S, Azizmohseni F. 2004. Biotransformation of hydrocortisone by a natural isolate of Nostoc muscorum. Phytochemistry 65:2205-2209.
30. Tamagnini P, Troshina O, Oxelfelt F, Salema R, Lindblad P. 1997. Hydrogenases in Nostoc sp. strain PCC 73102, a strain lacking a bidirectional enzyme. Appl Environ Microbiol 63:1801-1807.
31. Tolle J, Michel KP, Kruip J, Kahmann U, Preisfeld A, Pistorius EK. 2002. Localization and function of the ldiA homologue slr1295 in the cyanobacterium Synechocystis sp. strain PCC 6803. Microbiology 148:3293-3305.
32. Vermue M, Sikkema J, Verheul A, Bakker R, Tamper J. 1993. Toxicity of homologous series of organic solvents for the grampositive bacteria Arthrobacter and Nocardia sp. and gram negative bacteria Acinetobacter and Pseudomonas sp. Biotechnol Bioeng 42:747-758.