메뉴 건너뛰기




Volumn 23, Issue 4, 2009, Pages 223-230

Quantitative detection of PML-RARα fusion transcript by real-time PCR with a single primer pair

Author keywords

Alternative splicing; Lightcycler; PML RAR isoform; Real time quantitative PCR; Single primer pair

Indexed keywords

PROMYELOCYTIC LEUKEMIA PROTEIN; RETINOIC ACID RECEPTOR ALPHA;

EID: 68049085428     PISSN: 08878013     EISSN: 10982825     Source Type: Journal    
DOI: 10.1002/jcla.20306     Document Type: Article
Times cited : (4)

References (30)
  • 1
    • 0025089467 scopus 로고
    • Molecular analysis of acute promyelocytic leukemia breakpoint cluster region on chromosome 17
    • Borrow J, Goddard AD, Sheer D, Solomon E. Molecular analysis of acute promyelocytic leukemia breakpoint cluster region on chromosome 17. Science 1990;249:1577-1580. (Pubitemid 120031742)
    • (1990) Science , vol.249 , Issue.4976 , pp. 1577-1580
    • Borrow, J.1    Goddard, A.D.2    Sheer, D.3    Solomon, E.4
  • 2
    • 0025875679 scopus 로고
    • The PML-RAR alpha fusion mRNA generated by the t(15;17) translocation in acute promyelocytic leukemia encodes a functionally altered RAR
    • de The H, Lavau C, Marchio A, Chomienne C, Degos L, Dejean A. The PML-RAR alpha fusion mRNA generated by the t(15;17) translocation in acute promyelocytic leukemia encodes a functionally altered RAR. Cell 1991;66:675-684. (Pubitemid 121001703)
    • (1991) Cell , vol.66 , Issue.4 , pp. 675-684
    • De The, H.1    Lavau, C.2    Marchio, A.3    Chomienne, C.4    Degos, L.5    Dejean, A.6
  • 3
    • 0026513504 scopus 로고
    • Genomic variability and alternative splicing generate multiple PML/RAR alpha transcripts that encode aberrant PML proteins and PML/RAR alpha isoforms in acute promyelocytic leukaemia
    • Pandolfi PP, Alcalay M, Fagioli M, et al. Genomic variability and alternative splicing generate multiple PML/RAR alpha transcripts that encode aberrant PML proteins and PML/RAR alpha isoforms in acute promyelocytic leukaemia. EMBO J 1992;11: 1397-1407.
    • (1992) EMBO J , vol.11 , pp. 1397-1407
    • Pandolfi, P.P.1    Alcalay, M.2    Fagioli, M.3
  • 5
    • 0026608058 scopus 로고
    • Molecular rearrangements of the MYL gene in acute promyelocytic leukemia (APL, M3) define a breakpoint cluster region as well as some molecular variants
    • Tong JH, Dong S, Geng JP, et al. Molecular rearrangements of the MYL gene in acute promyelocytic leukemia (APL, M3) define a breakpoint cluster region as well as some molecular variants. Oncogene 1992;7:311-316.
    • (1992) Oncogene , vol.7 , pp. 311-316
    • Tong, J.H.1    Dong, S.2    Geng, J.P.3
  • 6
    • 0026507163 scopus 로고
    • Occurrence of distinct PML-RAR-alpha fusion gene isoforms in patients with acute promyelocytic leukemia detected by reverse transcriptase/polymerase chain reaction
    • Chen SJ, Chen Z, Chen A, et al. Occurrence of distinct PML-RAR-alpha fusion gene isoforms in patients with acute promyelocytic leukemia detected by reverse transcriptase/polymerase chain reaction. Oncogene 1992;7:1223-1232.
    • (1992) Oncogene , vol.7 , pp. 1223-1232
    • Chen, S.J.1    Chen, Z.2    Chen, A.3
  • 7
    • 0030812198 scopus 로고    scopus 로고
    • Association of PML-RAR alpha fusion mRNA type with pretreatment hematologic characteristics but not treatment outcome in acute promyelocytic leukemia: An intergroup molecular study
    • Gallagher RE, Willman CL, Slack JL, et al. Association of PML-RAR alpha fusion mRNA type with pretreatment hematologic characteristics but not treatment outcome in acute promyelocytic leukemia: An intergroup molecular study. Blood 1997;90: 1656-1663.
    • (1997) Blood , vol.90 , pp. 1656-1663
    • Gallagher, R.E.1    Willman, C.L.2    Slack, J.L.3
  • 8
    • 0032724514 scopus 로고    scopus 로고
    • A novel, non-nested reverse-transcriptase polymerase chain reaction (RT- PCR) test for the detection of the t(15;17) translocation: A comparative study of RT-PCR cytogenetics, and fluorescence in situ hybridization
    • DOI 10.1016/S1084-8592(99)80023-X
    • Rennert H, Golde T, Wilson RB, Spitalnik SL, Van Deerlin VM, Leonard DG. A novel, non-nested reverse-transcriptase polymerase chain reaction (RT-PCR) test for the detection of the t(15;17) translocation: A comparative study of RT-PCR cytogenetics, and fluorescence In situ hybridization. Mol Diagn 1999;4:195-209. (Pubitemid 29517549)
    • (1999) Molecular Diagnosis , vol.4 , Issue.3 , pp. 195-209
    • Rennert, H.1
  • 9
    • 0026637493 scopus 로고
    • Expression pattern of the RAR alpha-PML fusion gene in acute promyelocytic leukemia
    • Alcalay M, Zangrilli D, Fagioli M, et al. Expression pattern of the RAR alpha-PML fusion gene in acute promyelocytic leukemia. Proc Natl Acad Sci U S A 1992;89:4840-4844.
    • (1992) Proc Natl Acad Sci U S A , vol.89 , pp. 4840-4844
    • Alcalay, M.1    Zangrilli, D.2    Fagioli, M.3
  • 10
    • 0033564337 scopus 로고    scopus 로고
    • Presenting white blood cell count and kinetics of molecular remission predict prognosis in acute promyelocytic leukemia treated with all-trans retinoic acid: Result of the randomized MRC trial
    • Burnett AK, Grimwade D, Solomon E, Wheatley K, Goldstone AH. Presenting white blood cell count and kinetics of molecular remission predict prognosis in acute promyelocytic leukemia treated with all-trans retinoic acid: Result of the Randomized MRC Trial. Blood 1999;93:4131-4143. (Pubitemid 29279255)
    • (1999) Blood , vol.93 , Issue.12 , pp. 4131-4143
    • Burnett, A.K.1    Grimwade, D.2    Solomon, E.3    Wheatley, K.4    Goldstone, A.H.5
  • 11
    • 0038446666 scopus 로고    scopus 로고
    • Quantitative real-time RT-PCR analysis of PML-RAR alpha mRNA in acute promyelocytic leukemia: Assessment of prognostic significance in adult patients from intergroup protocol 0129
    • DOI 10.1182/blood-2002-05-1357
    • Gallagher RE, Yeap BY, Bi W, et al. Quantitative real-time RT-PCR analysis of PML-RAR alpha mRNA in acute promyelocytic leukemia: Assessment of prognostic significance in adult patients from intergroup protocol 0129. Blood 2003;101: 2521-2528. (Pubitemid 36857607)
    • (2003) Blood , vol.101 , Issue.7 , pp. 2521-2528
    • Gallagher, R.E.1    Yeap, B.Y.2    Bi, W.3    Livak, K.J.4    Beaubier, N.5    Rao, S.6    Bloomfield, C.D.7    Appelbaum, F.R.8    Tallman, M.S.9    Slack, J.L.10    Willman, C.L.11
  • 12
    • 0027194394 scopus 로고
    • Acute promyelocytic leukemia: Clinical relevance of two major PML-RARalpha isoforms and detection of minimal residual disease by retrotranscriptase/polymerase chain reaction to predict relapse
    • Huang W, Sun GL, Li XS, et al. Acute promyelocytic leukemia: clinical relevance of two major PML-RAR alpha isoforms and detection of minimal residual disease by retrotranscriptase/polymerase chain reaction to predict relapse. Blood 1993;82: 1264-1269. (Pubitemid 23254002)
    • (1993) Blood , vol.82 , Issue.4 , pp. 1264-1269
    • Huang, W.1    Sun, G.-L.2    Li, X.-S.3    Cao, Q.4    Lu, Y.5    Jang, G.-S.6    Zhang, F.-Q.7    Chai -, J.R.8    Wang, Z.-Y.9    Waxman, S.10    Chen, Z.11    Chen, S.-J.12
  • 13
    • 0027937940 scopus 로고
    • Early mortality and the retinoic acid syndrome in acute promyelocytic leukemia: Impact of leukocytosis, low-dose chemotherapy, PMN/RAR-alpha isoform, and CD13 expression in patients treated with all-trans retinoic acid
    • Vahdat L, Maslak P, Miller Jr WH, et al. Early mortality and the retinoic acid syndrome in acute promyelocytic leukemia: Impact of leukocytosis, low-dose chemotherapy, PMN/RAR-alpha isoform, and CD13 expression in patients treated with all-trans retinoic acid. Blood 1994;84:3843-3849. (Pubitemid 24979772)
    • (1994) Blood , vol.84 , Issue.11 , pp. 3843-3849
    • Vahdat, L.1    Maslak, P.2    Miller Jr., W.H.3    Eardley, A.4    Heller, G.5    Scheinberg, D.A.6    Warrell Jr., R.P.7
  • 14
    • 0035525767 scopus 로고    scopus 로고
    • Prognostic significance of minimal residual disease detection and PML/RAR-alpha isoform type: Long-term follow-up in acute promyelocytic leukemia
    • Jurcic JG, Nimer SD, Scheinberg DA, DeBlasio T, Warrell Jr RP, Miller Jr WH. Prognostic significance of minimal residual disease detection and PML/RAR-alpha isoform type: Long-term follow-up in acute promyelocytic leukemia. Blood 2001;98:2651-2656.
    • (2001) Blood , vol.98 , pp. 2651-2656
    • Jurcic, J.G.1    Nimer, S.D.2    Scheinberg, D.A.3    Deblasio, T.4    Warrell Jr., R.P.5    Miller Jr., W.H.6
  • 15
    • 0029162610 scopus 로고
    • Characterization of acute promyelocytic leukemia cases with PML-RAR alpha break/fusion sites in PML exon 6: Identification of a subgroup with decreased in vitro responsiveness to all-trans retinoic acid
    • Gallagher RE, Li YP, Rao S, et al. Characterization of acute promyelocytic leukemia cases with PML-RAR alpha break/fusion sites in PML exon 6: Identification of a subgroup with decreased in vitro responsiveness to all-trans retinoic acid. Blood 1995;86: 1540-1547.
    • (1995) Blood , vol.86 , pp. 1540-1547
    • Gallagher, R.E.1    Li, Y.P.2    Rao, S.3
  • 17
    • 0032878343 scopus 로고    scopus 로고
    • Detection of minimal residual disease in acute myeloid leukaemia: Methodologies, clinical and biological significance
    • DOI 10.1046/j.1365-2141.1999.01522.x
    • Yin JA, Tobal K. Detection of minimal residual disease in acute myeloid leukaemia: Methodologies, clinical and biological significance. Br J Haematol 1999;106:578-590. (Pubitemid 29434196)
    • (1999) British Journal of Haematology , vol.106 , Issue.3 , pp. 578-590
    • Liu Yin, J.A.1    Tobal, K.2
  • 18
    • 0035158509 scopus 로고    scopus 로고
    • Pulsed ATRA as single therapy restores long-term remission in PML-RARalpha-positive acute promyelocytic leukemia patients: Real time quantification of minimal residual disease. a pilot study
    • Visani G, Buonamici S, Malagola M, et al. Pulsed ATRA as single therapy restores long-term remission in PML-RARalpha-positive acute promyelocytic leukemia patients: Real time quantification of minimal residual disease. A pilot study. Leukemia 2001;15:1696-1700. (Pubitemid 33061835)
    • (2001) Leukemia , vol.15 , Issue.11 , pp. 1696-1700
    • Visani, G.1    Buonamici, S.2    Malagola, M.3    Isidori, A.4    Piccaluga, P.P.5    Martinelli, G.6    Ottaviani, E.7    Grafone, T.8    Baccarani, M.9    Tura, S.10
  • 19
    • 0026496751 scopus 로고
    • Diagnosis of acute promyelocytic leukaemia by RT-PCR: Detection of PML-RARA and RARA-PML fusion transcripts
    • Borrow J, Goddard AD, Gibbons B, et al. Diagnosis of acute promyelocytic leukaemia by RT-PCR: Detection of PML-RARA and RARA-PML fusion transcripts. Br J Haematol 1992;82: 529-540.
    • (1992) Br J Haematol , vol.82 , pp. 529-540
    • Borrow, J.1    Goddard, A.D.2    Gibbons, B.3
  • 20
    • 0032147033 scopus 로고    scopus 로고
    • Early detection of relapse by prospective reverse transcriptase- polymerase chain reaction analysis of the PML/RARalpha fusion gene in patients with acute promyelocytic leukemia enrolled in the GIMEMA-AIEOP multi-center "AIDA" trial GIMEMA-AIEOP Multicenter "AIDA" Trial
    • Diverio D, Rossi V, Avvisati G, et al. Early detection of relapse by prospective reverse transcriptase-polymerase chain reaction analysis of the PML/RARalpha fusion gene in patients with acute promyelocytic leukemia enrolled in the GIMEMA-AIEOP multi-center "AIDA" trial GIMEMA-AIEOP Multicenter "AIDA" Trial. Blood 1998;92:784-789.
    • (1998) Blood , vol.92 , pp. 784-789
    • Diverio, D.1    Rossi, V.2    Avvisati, G.3
  • 22
    • 9144222001 scopus 로고    scopus 로고
    • Standardization and quality control studies of "real-time" quantitative reverse transcriptase polymerase chain reaction of fusion gene transcripts for residual disease detection in leukemia - A Europe Against Cancer program
    • Gabert J, Beillard E, van der Velden VH, et al. Standardization and quality control studies of "real-time" quantitative reverse transcriptase polymerase chain reaction of fusion gene transcripts for residual disease detection in leukemia - a Europe Against Cancer program. Leukemia 2003;17:2318-2357.
    • (2003) Leukemia , vol.17 , pp. 2318-2357
    • Gabert, J.1    Beillard, E.2    Van Der Velden, V.H.3
  • 23
    • 0141923916 scopus 로고    scopus 로고
    • + acute myeloid leukemia based on quantification of fusion transcripts
    • DOI 10.1182/blood-2003-03-0880
    • Schnittger S, Weisser M, Schoch C, Hiddemann W, Haferlach T, Kern W. New score predicting for prognosis in PML-RARA+, AML1-ETO+, or CBFBMYH11+ acute myeloid leukemia based on quantification of fusion transcripts. Blood 2003;102:2746-2755. (Pubitemid 37248843)
    • (2003) Blood , vol.102 , Issue.8 , pp. 2746-2755
    • Schnittger, S.1    Weisser, M.2    Schoch, C.3    Hiddemann, W.4    Haferlach, T.5    Kern, W.6
  • 24
    • 0027237223 scopus 로고
    • Detection of minimal residual disease in acute promyelocytic leukemia by a reverse transcription polymerase chain reaction assay for the PML/RAR-alpha fusion mRNA
    • Miller Jr WH, Levine K, DeBlasio A, Frankel SR, Dmitrovsky E, Warrell Jr RP. Detection of minimal residual disease in acute promyelocytic leukemia by a reverse transcription polymerase chain reaction assay for the PML/RAR-alpha fusion mRNA. Blood 1993;82:1689-1694. (Pubitemid 23278757)
    • (1993) Blood , vol.82 , Issue.6 , pp. 1689-1694
    • Miller Jr., W.H.1    Levine, K.2    Deblasio, A.3    Frankel, S.R.4    Dmitrovsky, E.5    Warrell Jr., R.P.6
  • 26
    • 36148948610 scopus 로고    scopus 로고
    • Detecting PML-RARalpha transcript in acute promyelocytic leukemia using real-time quantitative RT-PCR
    • Zhu HH, Liu YR, Qin YZ, et al. Detecting PML-RARalpha transcript in acute promyelocytic leukemia using real-time quantitative RT-PCR. Chin Med J (Engl) 2007;120:1803-1808.
    • (2007) Chin Med J (Engl) , vol.120 , pp. 1803-1808
    • Zhu, H.H.1    Liu, Y.R.2    Qin, Y.Z.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.