The devil is in the details...or not? A primer on individual patient data meta-analysis

Annals of Internal Medicine

Volumn 151, Issue 2, 2009, Pages

  Sud, Sachin ^a   Douketis, James ^b  

^a UNIVERSITY OF TORONTO   (Canada)

^b MCMASTER UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CARBAMAZEPINE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; LYMPHOCYTE ANTIBODY; VALPROIC ACID;

CLINICAL TRIAL; DATA ANALYSIS; DATA BASE; DATA EXTRACTION; EDITORIAL; EFFECT SIZE; EPILEPSY; HEART INFARCTION; HUMAN; HYPOTHESIS; MEDICAL INFORMATION; META ANALYSIS; MORTALITY; OUTCOME ASSESSMENT; PATIENT CODING; PRIORITY JOURNAL; QUALITY OF LIFE; QUANTITATIVE ANALYSIS; RENAL GRAFT DYSFUNCTION; SAMPLE SIZE; STATISTICAL ANALYSIS; SURVIVAL; EPIDEMIOLOGY;

BIAS (EPIDEMIOLOGY); DATA INTERPRETATION, STATISTICAL; HUMANS; META-ANALYSIS AS TOPIC;

EID: 67949115666     PISSN: 00034819     EISSN: 15393704     Source Type: Journal    
DOI: 10.7326/0003-4819-151-2-200907210-02002     Document Type: Editorial

References (14)

1. DerSimonian R, Laird N. Meta-analysis in clinical trials. Control Clin Trials. 1986;7:177-88.
2. Sutton AJ, Abrams KR, Jones DR, Sheldon TA, Song F. Methods for Meta-analysis in Medical Research. Chichester: John Wiley and Sons Ltd; 2004.
3. Begg CB, Berlin JA. Publication bias: a problem in interpreting medical data. J R Stat Soc Ser A Stat Soc. 1988;151:419-63.
4. Higgins JPT, Green S, eds. Identifying and measuring heterogeneity. Cochrane Handbook for Systematic Reviews of Interventions 4.2.5 [updated May 2005]. In: Cochrane Library, Issue 3, 2005. Chichester, UK: John Wiley and Sons, Ltd. www.rees-france.com/IMG/pdf/2005-handbook-cochrane- systematic-review-.pdf (accessed 5 Jun 09).
5. Tierney JF, Stewart LA. Investigating patient exclusion bias in metaanalysis. Int J Epidemiology. 2005;34:79-87.
6. Schulz KF, Chalmers I, Hayes RJ, Altman DG. Empirical evidence of bias. Dimensions of methodological quality associated with estimates of treatment effects in controlled trials. JAMA. 1995;273:408-12.
7. Chalmers I. The Cochrane collaboration: preparing, maintaining, and disseminating systematic reviews of the effects of health care. Ann N Y Acad Sci. 1993;703:156-63.
8. Stewart LA, Tierney JF. To IPD or not to IPD? Advantages and disadvantages of systematic reviews using individual patient data. Eval Health Prof. 2002;25:76-97.
9. ACE Inhibitor Myocardial Infarction Collaborative Group. Indications for ACE inhibitors in the early treatment of acute myocardial infarction: systematic overview of individual data from 100, 000 patients in randomized trials. Circulation. 1998;97:2202-12.
10. Berlin JA, Santanna J, Schmid CH, Szczech LA, Feldman HI, for the Anti-lymphocyte Antibody Induction Therapy Study Group. Individual patient- versus group-level data meta-regressions for the investigation of treatment effect modifiers: ecological bias rears its ugly head. Stat Med. 2002;21:371-87.
11. Lambert PC, Sutton AJ, Abrams KR, Jones DR. A comparison of summary patient-level covariates in meta-regression with individual patient data meta-analysis. J Clin Epidemiol. 2002;55:86-94.
12. Williamson PR, Marson AG, Tudur C, Hutton JL, Chadwick D. Individual patient data meta-analysis of randomized anti-epileptic drug monotherapy trials. J Eval Clin Pract. 2000;6:205-14.
13. Simmonds MC, Higgins JP, Stewart LA, et al. Meta-analysis of individual patient data from randomized trials: a review of methods used in practice. Clin Trials. 2005;2:209-17.
14. Stewart LA, Tierney JF, Clarke M. Chapter 19: Reviews of individual patient data. In: Higgins JP, Green S, eds. Cochrane Handbook for Systematic Reviews of Interventions. Version 5.0.1 (updated Sep 2008). The Cochrane Collaboration; 2008.