Diabetes risk: Antioxidants or lifestyle?

American Journal of Clinical Nutrition

Volumn 90, Issue 2, 2009, Pages 253-254

  Meydani, Mohsen ^a   Azzi, Angelo ^a  

^a TUFTS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TOCOPHEROL; ANTIOXIDANT; ASCORBIC ACID; BETA CAROTENE; INSULIN; REACTIVE OXYGEN METABOLITE;

CARDIOVASCULAR DISEASE; CLINICAL TRIAL; DIET SUPPLEMENTATION; EDITORIAL; EXERCISE; GLUCOSE INTOLERANCE; HUMAN; IMMOBILIZATION; INSULIN RESISTANCE; LIFESTYLE MODIFICATION; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OBESITY; OXIDATIVE STRESS; PANCREAS ISLET BETA CELL; PRIMARY PREVENTION; RISK ASSESSMENT; VITAMIN INTAKE; DRUG EFFECT; LIFESTYLE; METABOLISM; NOTE; OXIDATION REDUCTION REACTION; PHYSIOLOGY; RISK FACTOR;

ANTIOXIDANTS; CARDIOVASCULAR DISEASES; DIABETES MELLITUS, TYPE 2; EXERCISE; HUMANS; LIFE STYLE; OBESITY; OXIDATION-REDUCTION; OXIDATIVE STRESS; RISK FACTORS;

EID: 67949103614     PISSN: 00029165     EISSN: None     Source Type: Journal    
DOI: 10.3945/ajcn.2009.28177     Document Type: Editorial

References (12)

1. Harris MI, Flegal KM, Cowie CC, et al. Prevalence of diabetes, impaired fasting glucose, and impaired glucose tolerance in U.S. adults: the Third National Health and Nutrition Examination Survey, 1988-1994. Diabetes Care 1998;21:518-524
2. Hajer GR, van Haeften TW, Visseren FL. Adipose tissue dysfunction in obesity, diabetes, and vascular diseases. Eur Heart J 2008;29:2959-2971
3. Song Y, Cook NR, Albert CM, Van Denburgh M, Manson JE. Effects of vitamins C and E and β-carotene on the risk of type 2 diabetes in women at high risk of cardiovascular disease: a randomized controlled trial. Am J Clin Nutr 2009;90:429-437
4. Liu S, Ajani U, Chae C, et al. Long-term beta-carotene supplementation and risk of type 2 diabetes mellitus: a randomized controlled trial. JAMA 1999;282:1073-1075 (Pubitemid 29436456)
5. Heart Protection Collaborative Group. MRC/BHF Heart Protection Study of antioxidant vitamin supplementation in 20 536 high-risk individuals: a randomised placebo-controlled trial. Lancet 2002;360:23-33.
6. Czernichow S, Couthouis A, Bertrais S, et al. Antioxidant supplementation does not affect fasting plasma glucose in the Supplementation with Antioxidant Vitamins and Minerals (SU.VI.MAX) study in France: association with dietary intake and plasma concentrations. Am J Clin Nutr 2006;84:395-399 (Pubitemid 44699151)
7. Liu S, Lee IM, Song Y, et al. Vitamin E and risk of type 2 diabetes in the Women's Health Study randomized controlled trial. Diabetes 2006;55:2856-2862 (Pubitemid 44923687)
8. Kataja-Tuomola M, Sundell JR, Mannisto S, et al. Effect of alpha-tocopherol and beta-carotene supplementation on the incidence of type 2 diabetes. Diabetologia 2008;51:47-53.
9. Milman U, Blum S, Shapira C, et al. Vitamin E supplementation reduces cardiovascular events in a subgroup of middle-aged individuals with both type 2 diabetes mellitus and the haptoglobin 2-2 genotype: a prospective double-blinded clinical trial. Arterioscler Thromb Vasc Biol 2008;28:341-347 (Pubitemid 351161209)
10. Sies H. Total antioxidant capacity: appraisal of a concept. J Nutr 2007;137:1493-1495 (Pubitemid 46855492)
11. Freemantle N, Holmes J, Hockey A, Kumar S. How strong is the association between abdominal obesity and the incidence of type 2 diabetes? Int J Clin Pract 2008;62:1391-1396
12. Carey VJ, Walters EE, Colditz GA, et al. Body fat distribution and risk of non-insulin-dependent diabetes mellitus in women. The Nurses' Health Study. Am J Epidemiol 1997;145:614-619