The use of repetitive transcranial magnetic stimulation (rTMS) for the treatment of spasticity

Progress in Brain Research

Volumn 175, Issue , 2009, Pages 429-439

  Mori, Francesco ^a,c   Koch, Giacomo ^a,c   Foti, Calogero ^b   Bernardi, Giorgio ^a,c   Centonze, Diego ^a,c  

^a UNIVERSITY OF ROME TOR VERGATA   (Italy)

^b IRCCS FONDAZIONE SANTA LUCIA   (Italy)

^c UNIVERSITY OF ROME TOR VERGATA   (Italy)

Author keywords

H reflex; multiple sclerosis; rTMS; spasticty; transcranial magnetic stimulation

Indexed keywords

BACLOFEN; DIAZEPAM; SPASMOLYTIC AGENT; TIZANIDINE;

BRAIN INJURY; CEREBRAL PALSY; DAILY LIFE ACTIVITY; DISABILITY; HOFFMANN REFLEX; HUMAN; MOTOR CORTEX; MULTIPLE SCLEROSIS; MYOTATIC REFLEX; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PYRAMIDAL TRACT; QUALITY OF LIFE; REVIEW; SPASTICITY; SPINAL CORD INJURY; STROKE PATIENT; TRANSCRANIAL MAGNETIC STIMULATION;

H-REFLEX; HUMANS; MULTIPLE SCLEROSIS; MUSCLE SPASTICITY; TRANSCRANIAL MAGNETIC STIMULATION;

EID: 67949087916     PISSN: 00796123     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0079-6123(09)17528-3     Document Type: Review

References (61)

1. Baldissera F., Hultborn H., and Illert M. Integration in spinal neuronal systems. In: Brooks V.B. (Ed). Handbook of physiology, motor control (1981), Williams and Wilkins Publishing Company, Baltimore 509-595
2. Bareyre F.M., Kerschensteiner M., Raineteau O., Mettenleiter T.C., Weinmann O., and Schwab M.E. The injured spinal cord spontaneously forms a new intraspinal circuit in adult rats. Nature Neuroscience 7 (2004) 269-277
3. Berardelli A., Inghilleri M., Rothwell J.C., Romeo S., Currà A., Gilio F., et al. Facilitation of muscle evoked responses after repetitive cortical stimulation in man. Experimental Brain Research 122 1 (1998) 79-84
4. Boroojerdi B., Prager A., Muellbacher W., and Cohen L.G. Reduction of human visual cortex excitability using 1-Hz transcranial magnetic stimulation. Neurology 54 7 (2000) 1529-1531
5. Centonze D., Koch G., Versace V., Mori F., Rossi S., Brusa L., et al. Repetitive transcranial magnetic stimulation of the motor cortex ameliorates spasticity in multiple sclerosis. Neurology 68 13 (2007) 1045-1050
6. Chen R., Classen J., Gerloff C., Celnik P., Wassermann E.M., Hallett M., et al. Depression of motor cortex excitability by low-frequency transcranial magnetic stimulation. Neurology 48 5 (1997) 1398-1403
7. Civardi C., Cantello R., Asselman P., and Rothwell J.C. Transcranial magnetic stimulation can be used to test connections to primary motor areas from frontal and medial cortex in humans. Neuroimage 14 (2001) 1444-1453
8. Crone C., Johnsen L.L., Biering-Sorensen F., and Nielsen J.B. Appearance of reciprocal facilitation of ankle extensors from ankle flexors in patients with stroke or spinal cord injury. Brain 126 (2006) 495-507
9. Crone C., and Nielsen J. Central control of disynaptic reciprocal inhibition in humans. Acta Physiologica Scandinavica 152 (1994) 351-363
10. Crone C., Nielsen J., Petersen N., Ballegaard M., and Hultborn H. Disynaptic reciprocal inhibition of ankle extensors in spastic patients. Brain 117 (1994) 1161-1168
11. Crone C., Petersen N.T., Nielsen J.E., Hansen N.L., and Nielsen J.B. Reciprocal inhibition and corticospinal transmission in the arm and leg in patients with autosomal dominant pure spastic paraparesis (ADPSP). Brain 127 (2004) 2693-2702
12. Delwaide P.J., and Olivier E. Short-latency autogenic inhibition (Ib inhibition) in human spasticity. Journal of Neurology Neurosurgery and Psychiatry 51 (1988) 1546-1550
13. Dietz V. Gait disorder in spasticity and Parkinson's disease. Advances in Neurology 87 (2001) 143-154
14. Dietz V. Spinal cord pattern generators for locomotion. Clinical Neurophysiology 114 8 (2003) 1379-1389
15. el-Abd M.A., Ibrahim I.K., and Dietz V. Impaired activation pattern in antagonistic elbow muscles of patients with spastic hemiparesis: Contribution to movement disorder. Electromyography and Clinical Neurophysiology 33 (1993) 247-255
16. Faist M., Mazevet D., Dietz V., and Pierrot-Deseilligny E. A quantitative assessment of presynaptic inhibition of Ia afferents in spastics. Differences in hemiplegics and paraplegics. Brain 117 (1994) 1449-1455
17. Fregni F., and Pascual-Leone A. Technology insight: noninvasive brain stimulation in neurology-perspectives on the therapeutic potential of rTMS and tDCS. Natural Clinical Practices in Neurology 3 (2007) 383-393
18. Gorassini M.A., Knash M.E., Harvey P.J., Bennett D.J., and Yang J.F. Role of motoneurons in the generation of muscle spasms after spinal cord injury. Brain 127 (2004) 2247-2258
19. Heckmann C.J., Gorassini M.A., and Bennett D.J. Persistent inward currents in motoneuron dendrites: Implications for motor output. Muscle Nerve 31 (2005) 135-156
20. Heckman C.J., Lee R.H., and Brownstone R.M. Hyperexcitable dendrites in motoneurons and their neuromodulatory control during motor behavior. Trends Neuroscience 26 (2003) 688-695
21. Huang Y.Z., Edwards M.J., Rounis E., Bhatia K.P., and Rothwell J.C. Theta burst stimulation of the human motor cortex. Neuron 45 2 (2005) 201-206
22. Hultborn H., Brownstone R.B., Toth T.I., and Gossard J.P. Key mechanisms for setting the input-output gain across the motoneuron pool. Progress in Brain Research 143 (2004) 77-95
23. Hultborn H., Meunier S., Morin C., and Pierrot-Deseilligny E. Assessing changes in presynaptic inhibition of Ia fibres: a study in man and the cat. Journal of Physiology 389 (1987) 729-756
24. Izumi S., Kondo T., and Shindo K. Transcranial magnetic stimulation synchronized with maximal movement effort of the hemiplegic hand after stroke: a double-blinded controlled pilot study. Journal of Rehabilitation Medicine 40 1 (2008) 49-54
25. Katz R., and Pierrot-Deseilligny E. Recurrent inhibition of alpha-motoneurons in patients with upper motor neuron lesions. Brain 105 (1982) 103-124
26. Katz R., and Pierrot-Deseilligny E. Recurrent inhibition in humans. Progress in Neurobiology 57 (1999) 325-355
27. Koch G., Fernandez Del Olmo M., Cheeran B., Ruge D., Schippling S., Caltagirone C., et al. Focal stimulation of the posterior parietal cortex increases the excitability of the ipsilateral motor cortex. Journal of Neuroscience 27 (2007) 6815-6822
28. Koch G., Franca M., Del Olmo M.F., Cheeran B., Milton R., Alvarez Sauco M., et al. Time course of functional connectivity between dorsal premotor and contralateral motor cortex during movement selection. Journal of Neuroscience 26 28 (2006) 7452-7459
29. Mailis A., and Ashby P. Alterations in group Ia projections to motoneurons following spinal lesions in humans. Journal of Neurophysiology 64 (1990) 637-647
30. Málly J., and Dinya E. Recovery of motor disability and spasticity in post-stroke after repetitive transcranial magnetic stimulation (rTMS). Brain Research Bulletin 76 (2008) 388-395
31. Maynard F.M., Karunas R.S., and Waring W.P. Epidemiology of spasticity following traumatic spinal cord injury. Archives of Physical Medicine and Rehabilitation 71 (1990) 566-569
32. Meunier S., and Pierrot-Deseilligny E. Cortical control of presynaptic inhibition of Ia afferents in humans. Experimental Brain Research 119 (1998) 415-426
33. Mizuno Y., Tanaka R., and Yanagisawa N. Reciprocal group I inhibition of triceps surae motoneurons in man. Journal of Neurophysiology 34 (1971) 1010-1017
34. Murase N., Duque J., Mazzocchio R., and Cohen L.G. Influence of interhemispheric interactions on motor function in chronic stroke. Annals of Neurology 55 (2004) 400-409
35. Nickolls P., Collins D.F., Gorman R.B., Burke D., and Gandevia S.C. Forces consistent with plateau-like behaviour of spinal neurons evoked in patients with spinal cord injuries. Brain 127 (2004) 660-670
36. Nielsen J., Crone C., Sinkjaer T., Toft E., and Hultborn H. Central control of reciprocal inhibition during fictive dorsiflexion in man. Experimental Brain Research 104 (1995) 99-106
37. Nielsen J., and Petersen N. Evidence favouring different descending pathways to soleus motoneurones activated by magnetic brain stimulation in man. Journal of Physiology 486 (1995) 779-788
38. Nielsen J., Petersen N., and Crone C. Changes in transmission across synapses of Ia afferents in spastic patients. Brain 118 (1995) 995-1004
39. Nielsen J.B., Crone C., and Hultborn H. The spinal pathophysiology of spasticity - from a basic science point of view. Acta Physiology 189 (2007) 171-180
40. Nielsen J.F., and Sinkjaer T. Long-lasting depression of soleus motoneurons excitability following repetitive magnetic stimuli of the spinal cord in multiple sclerosis patients. Multiple Sclerosis 3 (1997) 18-30
41. Nielsen J.F., Sinkjaer T., and Jakobsen J. Treatment of spasticity with repetitive magnetic stimulation; a double-blind placebo-controlled study. Multiple Sclerosis 2 5 (1996) 227-232
42. Nitsche M.A., and Paulus W. Excitability changes induced in the human motor cortex by weak transcranial direct current stimulation. Journal of Physiology 527 (2000) 633-639
43. Peinemann A., Reimer B., Löer C., Quartarone A., Münchau A., Conrad B., et al. Long-lasting increase in corticospinal excitability after 1800 pulses of subthreshold 5 Hz repetitive TMS to the primary motor cortex. Clinical Neurophysiology 115 (2004) 1519-1526
44. Perez M.A., Lungholt B.K., and Nielsen J.B. Short-term adaptations in spinal cord circuits evoked by repetitive transcranial magnetic stimulation: Possible underlying mechanisms. Experimental Brain Research 162 2 (2005) 202-212
45. Pierrot-Deseilligny E., and Bussel B. Evidence for recurrent inhibition by motoneurons in human subjects. Brain Research 88 (1975) 105-108
46. Pierrot-Deseilligny E., Katz R., and Morin C. Evidence of Ib inhibition in human subjects. Brain Research 166 (1979) 176-179
47. Powers R.K., and Binder M.D. Input-output functions of mammalian motoneurons. Review of Physiology Biochemistry and Pharmacology 143 (2001) 137-263
48. Priori A., Berardelli A., Rona S., Accornero N., and Manfredi M. Polarization of the human motor cortex through the scalp. Neuroreport 9 (1998) 2257-2260
49. Raineteau O., and Schwab M.E. Plasticity of motor systems after incomplete spinal cord injury. Nature Reviews Neuroscience 2 (2001) 263-273
50. Raisman G. Neuronal plasticity in the septal nuclei of the adult rat. Brain Research 14 (1969) 25-48
51. Rekling J.C., Funk G.D., Bayliss D.A., Dong X.W., and Feldman J.L. Synaptic control of motoneuronal excitability. Physiology Reviews 80 (2000) 767-852
52. Rizzo M.A., Hadjimichael O.C., Preiningerova J., and Vollmer T.L. Prevalence and treatment of spasticity reported by multiple sclerosis patients. Multiple Sclerosis 10 (2004) 589-595
53. Rudomin P., and Schmidt R.F. Presynaptic inhibition in the vertebrate spinal cord revisited. Experimental Brain Research 129 (1999) 1-37
54. Siebner H.R., Filipovic S.R., Rowem J.B., Cordivari C., Gerschlager W., Rothwell J.C., et al. Patients with focal arm dystonia have increased sensitivity to slow-frequency repetitive TMS of the dorsal premotor cortex. Brain 126 (2003) 2710-2725
55. Sommerfeld D.K., Eek E.U., Svensson A.K., Holmqvist L.W., and von Arbin M.H. Spasticity after stroke: Its occurrence and association with motor impairments and activity limitations. Stroke 35 (2004) 134-139
56. Touge T., Gerschlager W., Brown P., and Rothwell J.C. Are the after-effects of low-frequency rTMS on motor cortex excitability due to changes in the efficacy of cortical synapses?. Clinical Neurophysiology 112 11 (2001) 2138-2145
57. Valero-Cabre A., Oliveri M., Gangitano M., and Pascual-Leone A. Modulation of spinal cord excitability by subthreshold repetitive transcranial magnetic stimulation of the primary motor cortex in humans. Neuroreport 4, 12 17 (2001) 3845-3848
58. Valle A.C., Dionisio K., Pitskel N.B., Pascual-Leone A., Orsati F., Ferreira M.J., et al. Low and high frequency repetitive transcranial magnetic stimulation for the treatment of spasticity. Developmental Medicine and Child Neurology 49 7 (2007) 534-538
59. Woolacott A.J., and Burne J.A. The tonic stretch reflex and spastic hypertonia after spinal cord injury. Experimental Brain Research 174 (2006) 386-396
60. Yanagisawa N., Tanaka R., and Ito Z. Reciprocal Ia inhibition in spastic hemiplegia of man. Brain 99 (1976) 555-574
61. Young R.R. Spasticity: a review. Neurology 44 (1994) S12-S20