메뉴 건너뛰기




Volumn 17, Issue 2, 2009, Pages 116-121

Ultrasound usage in the head and neck surgeon's office

Author keywords

Diagnostic accuracy; Lymph node metastases; Office based ultrasonography; Thyroid and parathyroid masses

Indexed keywords

ASPIRATION BIOPSY; CANCER SCREENING; CYTOLOGY; DIAGNOSTIC ACCURACY; DIFFERENTIAL DIAGNOSIS; HEAD AND NECK CANCER; HEAD AND NECK SURGERY; HUMAN; MEDICAL PRACTICE; PARATHYROID ADENOMA; PARATHYROID DISEASE; PRIORITY JOURNAL; REVIEW; SQUAMOUS CELL CARCINOMA; SURGEON; THYROID DISEASE; TUMOR LOCALIZATION; TUMOR VOLUME; ULTRASOUND;

EID: 67849110379     PISSN: 10689508     EISSN: None     Source Type: Journal    
DOI: 10.1097/MOO.0b013e3283297042     Document Type: Review
Times cited : (25)

References (41)
  • 1
    • 67849102805 scopus 로고    scopus 로고
    • Ultrasound surveillance for head and neck cancer
    • Orloff LA, editor. Plural Publishers
    • Van den Brekel MWM, Castelijns JA. Ultrasound surveillance for head and neck cancer. In: Orloff LA, editor. Head and neck ultrasonography. Plural Publishers; 2008. pp. 309-327.
    • (2008) Head and Neck Ultrasonography , pp. 309-327
    • Van Den Brekel, M.W.M.1    Castelijns, J.A.2
  • 3
    • 30944455934 scopus 로고    scopus 로고
    • Assessment of cervical lymph node metastasis with different imaging methods in patients with head and neck squamous cell carcinoma
    • Akoglu E, Dutipek M, Bekis R, et al. Assessment of cervical lymph node metastasis with different imaging methods in patients with head and neck squamous cell carcinoma. J Otolaryngol 2005; 34:384-394. (Pubitemid 43111256)
    • (2005) Journal of Otolaryngology , vol.34 , Issue.6 , pp. 384-394
    • Akoglu, E.1    Dutipek, M.2    Bekis, R.3    Degirmenci, B.4    Ada, E.5    Guneri, A.6
  • 4
    • 59949104418 scopus 로고    scopus 로고
    • CT, MR, US, (18)-F-FDG PET/CT, and their combined use for the assessment of cervical lymph node metastases in squamous cell carcinoma of the head and neck
    • In this study, the sensitivity, specificity, and overall accuracy of different imaging techniques including 18-FDG-PET in the detection of lymph node metastases were compared. The overall accuracy for ultrasound was 94.8% for MRI and 95.3% for CT scans. There were no statistically significant differences between these methods. A combination of 18-FDG-PET and ultrasonography improved the overall accuracy to 97.0%
    • Yoon DY, Hwang HS, Chang SK, et al. CT, MR, US, (18)-F-FDG PET/CT, and their combined use for the assessment of cervical lymph node metastases in squamous cell carcinoma of the head and neck. Eur Radiol 2008; 19:634-642. In this study, the sensitivity, specificity, and overall accuracy of different imaging techniques including 18-FDG-PET in the detection of lymph node metastases were compared. The overall accuracy for ultrasound was 94.8% for MRI and 95.3% for CT scans. There were no statistically significant differences between these methods. A combination of 18-FDG-PET and ultrasonography improved the overall accuracy to 97.0%.
    • (2008) Eur Radiol , vol.19 , pp. 634-642
    • Yoon, D.Y.1    Hwang, H.S.2    Chang, S.K.3
  • 5
    • 1342266168 scopus 로고    scopus 로고
    • Necrosis in metastatic neck nodes: Diagnostic accuracy of CT, MR imaging, and US
    • King AD, Tse GM, Ahuja AT, et al. Necrosis in metastatic neck nodes: diagnostic accuracy of CT, MR imaging, and US. Radiology 2004; 230:720-726.
    • (2004) Radiology , vol.230 , pp. 720-726
    • King, A.D.1    Tse, G.M.2    Ahuja, A.T.3
  • 6
    • 39749111954 scopus 로고    scopus 로고
    • Ultrasound-guided core-needle biopsy in the diagnosis of head and neck masses: Indications, technique, and results
    • This study investigates whether USgFNAB improves the diagnostic accuracy of ultrasound in the identification of lymph node metastases
    • Pfeiffer J, Kayser G, Technau-Ihling K, et al. Ultrasound-guided core-needle biopsy in the diagnosis of head and neck masses: indications, technique, and results. Head Neck 2007; 29:1033-2040. This study investigates whether USgFNAB improves the diagnostic accuracy of ultrasound in the identification of lymph node metastases.
    • (2007) Head Neck , vol.29 , pp. 1033-2040
    • Pfeiffer, J.1    Kayser, G.2    Technau-Ihling, K.3
  • 7
    • 35348887678 scopus 로고    scopus 로고
    • Detection of lymph node metastases in head and neck cancer: A meta-analysis comparing US, USgFNAC, CT and MR imaging
    • This article reports of a meta-analysis based on MEDLINE, EMBASE, and Cochrane database search for studies on the diagnostic performances of different imaging techniques for identification of lymph node metastases in the neck. Ultrasonography, in combination with USgFNAB, has been demonstrated to be the most accurate imaging technique for this issue
    • de Bondt RB, Nelemans PJ, Hofman PA, et al. Detection of lymph node metastases in head and neck cancer: a meta-analysis comparing US, USgFNAC, CT and MR imaging. Eur J Radiol 2007; 64:266-272. This article reports of a meta-analysis based on MEDLINE, EMBASE, and Cochrane database search for studies on the diagnostic performances of different imaging techniques for identification of lymph node metastases in the neck. Ultrasonography, in combination with USgFNAB, has been demonstrated to be the most accurate imaging technique for this issue.
    • (2007) Eur J Radiol , vol.64 , pp. 266-272
    • De Bondt, R.B.1    Nelemans, P.J.2    Hofman, P.A.3
  • 8
    • 34247117419 scopus 로고    scopus 로고
    • What is important for ultrasound evaluation of occult metastatic lymph nodes in laryngeal cancer: Size, shape, vascularity or cytological findings?
    • This study reports an overall accuracy of ultrasound in combination with USgFNAB of 97% in the detection of occult lymph node metastases in patients with laryngeal cancer
    • Cvorovic L, Milutinovic Z, Strbac M, Markovski S. What is important for ultrasound evaluation of occult metastatic lymph nodes in laryngeal cancer: size, shape, vascularity or cytological findings? ORL J Otorhinolaryngol Relat Spec 2007; 69:172-175. This study reports an overall accuracy of ultrasound in combination with USgFNAB of 97% in the detection of occult lymph node metastases in patients with laryngeal cancer.
    • (2007) ORL J Otorhinolaryngol Relat Spec , vol.69 , pp. 172-175
    • Cvorovic, L.1    Milutinovic, Z.2    Strbac, M.3    Markovski, S.4
  • 10
    • 24644496324 scopus 로고    scopus 로고
    • Usefulness and limitations in ultrasonography for diagnosing neck lymph node metastases in patients with hypopharyngeal squamous cell carcinoma: Comparison with pathological findings following neck dissection
    • Beppu T, Sasaki T, Kawabata K, et al. Usefulness and limitations in ultrasonography for diagnosing neck lymph node metastases in patients with hypopharyngeal squamous cell carcinoma: comparison with pathological findings following neck dissection. Nippon Jibiinkoka Gakkai Kaiho 2005; 108:794-800.
    • (2005) Nippon Jibiinkoka Gakkai Kaiho , vol.108 , pp. 794-800
    • Beppu, T.1    Sasaki, T.2    Kawabata, K.3
  • 11
    • 27744509195 scopus 로고    scopus 로고
    • Imaging of cervical lymph nodes in head and neck cancer: The basics
    • Gor DM, Langer JE, Loevner LA. Imaging of cervical lymph nodes in head and neck cancer: the basics. Radiol Clin North Am 2006; 44:101-110.
    • (2006) Radiol Clin North Am , vol.44 , pp. 101-110
    • Gor, D.M.1    Langer, J.E.2    Loevner, L.A.3
  • 12
    • 84858372039 scopus 로고    scopus 로고
    • Tissue characterization of locoregionally advanced head-and-neck squamous cell carcinoma (HNSCC) using quantified ultrasonography: A prospective phase II study on prognostic relevance
    • DOI 10.1016/j.radonc.2007.04.003, PII S0167814007001508
    • Röper B, Nüse N, Busch R, et al. Tissue characterization of locoregionally advanced head-and-neck squamous cell carcinoma (HNSCC) using quantified ultrasonography: a prospective phase II study on prognostic relevance. Radiother Oncol 2007; 85:48-57. This study describes sonomorphologic and duplex sonographic characteristics of lymph nodes, which could be recognized as signs for malignancy (Table 2). (Pubitemid 47570060)
    • (2007) Radiotherapy and Oncology , vol.85 , Issue.1 , pp. 48-57
    • Roper, B.1    Nuse, N.2    Busch, R.3    Zimmermann, F.B.4    Nahrig, J.5    Molls, M.6
  • 13
    • 27844462921 scopus 로고    scopus 로고
    • Comparison of the sonographic detection of experimentally induced squamous cell carcinoma compared with the histological image
    • Jecker P, Brieger J, Döring S. Comparison of the sonographic detection of experimentally induced squamous cell carcinoma compared with the histological image. Ultraschall Med 2005; 26:399-405.
    • (2005) Ultraschall Med , vol.26 , pp. 399-405
    • Jecker, P.1    Brieger, J.2    Döring, S.3
  • 14
    • 33846938153 scopus 로고    scopus 로고
    • Neck lymph nodes: Prediction by computer-assisted contrast medium analysis?
    • DOI 10.1016/j.ultrasmedbio.2006.08.005, PII S0301562906017893
    • Zenk J, Bozzato A, Hornung J, et al. Neck lymph nodes: prediction by computer-assisted contrast medium analysis? Ultrasound Med Biol 2007; 33:246-253. In this study, the authors investigated subjective sonomorphologic parameters and compared the results with quantitative criteria obtained from computer analysis following intravenous injection of contrast agents. Peripheral perfusion pattern of a lymph node and the contrast wash-in time estimated by computer analysis were most significant related to malignancy. (Pubitemid 46240601)
    • (2007) Ultrasound in Medicine and Biology , vol.33 , Issue.2 , pp. 246-253
    • Zenk, J.1    Bozzato, A.2    Hornung, J.3    Gottwald, F.4    Rabe, C.5    Gill, S.6    Iro, H.7
  • 15
    • 58149360492 scopus 로고    scopus 로고
    • Papillary thyroid cancer: Controversies in the management of neck metastasis
    • Davidson HC, Park BJ, Johnson JT. Papillary thyroid cancer: controversies in the management of neck metastasis. Laryngoscope 2008; 118:2161-2165.
    • (2008) Laryngoscope , vol.118 , pp. 2161-2165
    • Davidson, H.C.1    Park, B.J.2    Johnson, J.T.3
  • 16
    • 35348935626 scopus 로고    scopus 로고
    • Sonographic findings in the surgical bed after thyroidectomy: Comparison of recurrent tumors and nonrecurrent lesions
    • Shin JH, Han BK, Ko EY, Kang SS. Sonographic findings in the surgical bed after thyroidectomy: comparison of recurrent tumors and nonrecurrent lesions. J Ultrasound Med 2007; 26:1359-1366.
    • (2007) J Ultrasound Med , vol.26 , pp. 1359-1366
    • Shin, J.H.1    Han, B.K.2    Ko, E.Y.3    Kang, S.S.4
  • 20
    • 38449110909 scopus 로고    scopus 로고
    • The role of ultrasound in the detection of cervical lymph node metastases in clinically N0 squamous cell carcinoma
    • Richards PS, Peacock TE. The role of ultrasound in the detection of cervical lymph node metastases in clinically N0 squamous cell carcinoma. Cancer Imaging 2007; 19:167-178.
    • (2007) Cancer Imaging , vol.19 , pp. 167-178
    • Richards, P.S.1    Peacock, T.E.2
  • 21
    • 40949152056 scopus 로고    scopus 로고
    • Otolaryngologist-head and neck surgeon-performed ultrasonography for parathyroid adenoma localization
    • Surgeon performed ultrasonography identified parathyroid adenomas to the correct side in 90% of cases and to the correct quadrant in 83% of cases. These results were significantly better than with conventional sestamibi scans
    • Gurney TA, Orloff LA. Otolaryngologist-head and neck surgeon-performed ultrasonography for parathyroid adenoma localization. Laryngoscope 2008; 118:243-246. Surgeon performed ultrasonography identified parathyroid adenomas to the correct side in 90% of cases and to the correct quadrant in 83% of cases. These results were significantly better than with conventional sestamibi scans.
    • (2008) Laryngoscope , vol.118 , pp. 243-246
    • Gurney, T.A.1    Orloff, L.A.2
  • 22
    • 37349060101 scopus 로고    scopus 로고
    • The role of ultrasonography in parathyroid surgery
    • This study also describes the high diagnostic accuracy of ultrasound in the preoperative evaluation of patients with parathyroidmasses compared to sestamibi scan
    • Boudreaux BA, Magnuson JS, Asher SA, et al. The role of ultrasonography in parathyroid surgery. Arch Otolaryngol Head Neck Surg 2007; 133:1240-1244. This study also describes the high diagnostic accuracy of ultrasound in the preoperative evaluation of patients with parathyroidmasses compared to sestamibi scan.
    • (2007) Arch Otolaryngol Head Neck Surg , vol.133 , pp. 1240-1244
    • Boudreaux, B.A.1    Magnuson, J.S.2    Asher, S.A.3
  • 23
    • 52449133801 scopus 로고    scopus 로고
    • Predicting the success of limited exploration for primary hyperparathyroidism using ultrasound, sestamibi, and intraoperative parathyroid hormone: Analysis of 1158 cases
    • In this study, the diagnostic accuracy of ultrasonography in patients with parathyroid disorder is compared to results of histologic examinations following limited neck exploration. Using ultrasound, it is possible to identify single abnormal glands in more than 80% of cases. Nevertheless, the technique showed some limitation in identifying unsuspected multiglandular disease
    • Siperstein A, Berber E, Barbosa GF, et al. Predicting the success of limited exploration for primary hyperparathyroidism using ultrasound, sestamibi, and intraoperative parathyroid hormone: analysis of 1158 cases. Ann Surg 2008; 248:420-428. In this study, the diagnostic accuracy of ultrasonography in patients with parathyroid disorder is compared to results of histologic examinations following limited neck exploration. Using ultrasound, it is possible to identify single abnormal glands in more than 80% of cases. Nevertheless, the technique showed some limitation in identifying unsuspected multiglandular disease.
    • (2008) Ann Surg , vol.248 , pp. 420-428
    • Siperstein, A.1    Berber, E.2    Barbosa, G.F.3
  • 24
    • 51649127813 scopus 로고    scopus 로고
    • Ultrasonography: Highly accuracy technique for preoperative localization of parathyroid adenoma
    • This article also describes the high diagnostic accuracy of ultrasonography in the preoperative localization of parathyroid adenoma, which is about 96% in patients with one abnormal parathyroid gland
    • Abboud B, Sleilaty G, Rabaa I, et al. Ultrasonography: highly accuracy technique for preoperative localization of parathyroid adenoma. Laryngoscope 2008; 118:1574-1578. This article also describes the high diagnostic accuracy of ultrasonography in the preoperative localization of parathyroid adenoma, which is about 96% in patients with one abnormal parathyroid gland.
    • (2008) Laryngoscope , vol.118 , pp. 1574-1578
    • Abboud, B.1    Sleilaty, G.2    Rabaa, I.3
  • 25
    • 34548455776 scopus 로고    scopus 로고
    • Utility of ultrasound-guided fine-needle aspiration of parathyroid adenomas for localization before minimally invasive parathyroidectomy
    • Abraham D, Sharma PK, Bentz J, et al. Utility of ultrasound-guided fine-needle aspiration of parathyroid adenomas for localization before minimally invasive parathyroidectomy. Endocr Pract 2007; 13:333-337.
    • (2007) Endocr Pract , vol.13 , pp. 333-337
    • Abraham, D.1    Sharma, P.K.2    Bentz, J.3
  • 26
    • 42449155854 scopus 로고    scopus 로고
    • Surgeon performed ultrasound facilitates minimally invasive parathyroidectomy by the focused lateral miniincision approach
    • In this study, the results of surgeon-performed ultrasound were compared to the results of radiologist-performed ultrasound in patients who were scheduled for minimally invasive parathyroid surgery. The rate of sonographically correctly localization of parathyroid gland adenoma was 83% in the surgeon-performed sonography group and 82% in the radiologist-performed group. In conclusion, surgeon-performed ultrasonography proved to be a useful tool prior to minimally invasive surgery when performed by an experienced surgeon
    • Soon PS, Delbridge LW, Sywak MS, et al. Surgeon performed ultrasound facilitates minimally invasive parathyroidectomy by the focused lateral miniincision approach. World J Surg 2008; 32:766-771. In this study, the results of surgeon-performed ultrasound were compared to the results of radiologist-performed ultrasound in patients who were scheduled for minimally invasive parathyroid surgery. The rate of sonographically correctly localization of parathyroid gland adenoma was 83% in the surgeon-performed sonography group and 82% in the radiologist-performed group. In conclusion, surgeon-performed ultrasonography proved to be a useful tool prior to minimally invasive surgery when performed by an experienced surgeon.
    • (2008) World J Surg , vol.32 , pp. 766-771
    • Soon, P.S.1    Delbridge, L.W.2    Sywak, M.S.3
  • 27
    • 40949151625 scopus 로고    scopus 로고
    • Ultrasound-guided fine needle aspiration biopsy of thyroid nodules performed in the office
    • DOI 10.1097/MLG.0b013e318157465d
    • Seiberling KA, Dutra JC, Gunn J. Ultrasound-guided fine needle aspiration biopsy of thyroid nodules performed in the office. Laryngoscope 2008; 118:228-231. In this study, the diagnostic accuracy of office-based USgFNAB compared with the radiology literature is described. The authors found satisfactory specimens in 81.2% of cases, which was comparable or even better than that reported in the radiology literature. Interestingly, the unsatisfactory rate was higher in patients with large nodules. (Pubitemid 351640191)
    • (2008) Laryngoscope , vol.118 , Issue.2 , pp. 228-231
    • Seiberling, K.A.1    Dutra, J.C.2    Gunn, J.3
  • 28
    • 50249170314 scopus 로고    scopus 로고
    • Fine-needle aspiration biopsy versus ultrasound-guided fine-needle aspiration biopsy: Cost-effectiveness as a frontline diagnostic modality for solitary thyroid nodules
    • Khalid AN, Ouraishi SA, Hollenbeak CS, Stack BC Jr. Fine-needle aspiration biopsy versus ultrasound-guided fine-needle aspiration biopsy: cost-effectiveness as a frontline diagnostic modality for solitary thyroid nodules. Head Neck 2008; 30:1035-1039.
    • (2008) Head Neck , vol.30 , pp. 1035-1039
    • Khalid, A.N.1    Ouraishi, S.A.2    Hollenbeak, C.S.3    Stack Jr., B.C.4
  • 30
    • 45849141907 scopus 로고    scopus 로고
    • Evidence-based assessment of the role of ultrasonography in the management of benign thyroid nodules
    • Morris LF, Ragavendra N, Yeh MW. Evidence-based assessment of the role of ultrasonography in the management of benign thyroid nodules. World J Surg 2008; 32:1253-1263.
    • (2008) World J Surg , vol.32 , pp. 1253-1263
    • Morris, L.F.1    Ragavendra, N.2    Yeh, M.W.3
  • 31
    • 34249845909 scopus 로고    scopus 로고
    • US features of thyroid malignancy: Pearls and pitfalls
    • Hoang JK, Lee WK, Lee M, et al. US features of thyroid malignancy: pearls and pitfalls. Radiographics 2007; 27:847-860.
    • (2007) Radiographics , vol.27 , pp. 847-860
    • Hoang, J.K.1    Lee, W.K.2    Lee, M.3
  • 32
    • 37449003195 scopus 로고    scopus 로고
    • Evaluation and imaging of a thyroid nodule
    • Coltrera MD. Evaluation and imaging of a thyroid nodule. Surg Oncol Clin N Am 2008; 17:37-56.
    • (2008) Surg Oncol Clin N Am , vol.17 , pp. 37-56
    • Coltrera, M.D.1
  • 33
    • 43449092874 scopus 로고    scopus 로고
    • US-elastography in the differential diagnosis of benign and malignant thyroid nodules
    • DOI 10.1089/thy.2007.0323
    • Asteria C, Giovanardi A, Pizzocaro A, et al. US elastography in the differential diagnosis of benign and malignant thyroid nodules. Thyroid 2008; 18:523-531. This paper describes the principles of elastography and some characteristics of malignant and benign thyroid masses. (Pubitemid 351667834)
    • (2008) Thyroid , vol.18 , Issue.5 , pp. 523-531
    • Asteria, C.1    Giovanardi, A.2    Pizzocaro, A.3    Cozzaglio, L.4    Morabito, A.5    Somalvico, F.6    Zoppo, A.7
  • 34
    • 34249874877 scopus 로고    scopus 로고
    • Ultrasound thyroid elastography using carotid artery pulsation: Preliminary study
    • Bae U, Dighe M, Dubinsky T, et al. Ultrasound thyroid elastography using carotid artery pulsation: preliminary study. J Ultraosund Med 2007; 26:797-805. In this preliminary study, the authors could demonstrate a significant higher stiffness of papillary carcinomas compared with benign nodular goiter. The carotid artery pulsation was used as the compression source. (Pubitemid 46870347)
    • (2007) Journal of Ultrasound in Medicine , vol.26 , Issue.6 , pp. 797-805
    • Bae, U.1    Dighe, M.2    Dubinsky, T.3    Minoshima, S.4    Shamdasani, V.5    Kim, Y.6
  • 35
    • 37349115353 scopus 로고    scopus 로고
    • Impact of preoperative ultrasonographic staging of the neck in papillary thyroid carcinoma
    • Gonzalez HE, Cruz F, O'Brien A, et al. Impact of preoperative ultrasonographic staging of the neck in papillary thyroid carcinoma. Arch Otolaryngol Head Neck Surg 2007; 133:1258-1262.
    • (2007) Arch Otolaryngol Head Neck Surg , vol.133 , pp. 1258-1262
    • Gonzalez, H.E.1    Cruz, F.2    O'Brien, A.3
  • 36
    • 51449117016 scopus 로고    scopus 로고
    • The estimation of the thyroid volume before surgery: An important prerequisite for minimally invasive thyroidectomy
    • Ruggieri M, Fumarola A, Straniero A, et al. The estimation of the thyroid volume before surgery: an important prerequisite for minimally invasive thyroidectomy. Langenbecks Arch Surg 2008; 393:721-724.
    • (2008) Langenbecks Arch Surg , vol.393 , pp. 721-724
    • Ruggieri, M.1    Fumarola, A.2    Straniero, A.3
  • 38
    • 46349085761 scopus 로고    scopus 로고
    • Extrathyroid extension of well differentiated papillary thyroid microcarcinoma on US
    • Kwak JY, Kim EK, Youk JH, et al. Extrathyroid extension of well differentiated papillary thyroid microcarcinoma on US. Thyroid 2008; 18:609-614.
    • (2008) Thyroid , vol.18 , pp. 609-614
    • Kwak, J.Y.1    Kim, E.K.2    Youk, J.H.3
  • 40
    • 41649084826 scopus 로고    scopus 로고
    • Quantification of thyroid volume using 3-D ultrasound imaging
    • Kollorz EK, Hahn DA, Linke R, et al. Quantification of thyroid volume using 3-D ultrasound imaging. IEEE Trans Med Imaging 2008; 27:457-466.
    • (2008) IEEE Trans Med Imaging , vol.27 , pp. 457-466
    • Kollorz, E.K.1    Hahn, D.A.2    Linke, R.3
  • 41
    • 37049012667 scopus 로고    scopus 로고
    • Two-Dimensional Ultrasound Measurement of Thyroid Gland Volume: A New Equation with Higher Correlation with 3-D Ultrasound Measurement
    • DOI 10.1016/j.ultrasmedbio.2007.06.016, PII S0301562907003171
    • Ying M, Yung DM, Ho KK. Two-dimensional ultrasound measurement of thyroid gland volume: a new equation with higher correlation with 3-D ultrasound measurement. Ultrasound Med Biol 2008; 34:56-63. (Pubitemid 350250978)
    • (2008) Ultrasound in Medicine and Biology , vol.34 , Issue.1 , pp. 56-63
    • Ying, M.1    Yung, D.M.C.2    Ho, K.K.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.