Possibilities and limits of X-ray microtomography for in vivo and ex vivo detection of vascular calcifications

International Journal of Cardiovascular Imaging

Volumn 25, Issue 6, 2009, Pages 615-624

  Postnov, Andrei A ^a   D'Haese, P C ^a   Neven, E ^a   De Clerck, N M ^a   Persy, V P ^a  

^a UNIVERSITY OF ANTWERP   (Belgium)

Author keywords

Chronic renal failure; Image analysis; Vascular calcifications; X ray microtomography

Indexed keywords

CALCIUM;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATOMIC ABSORPTION SPECTROMETRY; BLOOD VESSEL CALCIFICATION; CHRONIC KIDNEY FAILURE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DIAGNOSTIC ACCURACY; EX VIVO STUDY; IMAGE ANALYSIS; IN VIVO STUDY; INTERMETHOD COMPARISON; MALE; MICRO-COMPUTED TOMOGRAPHY; MORPHOMETRICS; NON INVASIVE PROCEDURE; NONHUMAN; QUANTITATIVE ANALYSIS; RAT; RELIABILITY; SENSITIVITY AND SPECIFICITY; TISSUE LEVEL;

ADENINE; ANIMALS; AORTA; AORTIC DISEASES; AORTOGRAPHY; CALCINOSIS; CALCIUM; DISEASE MODELS, ANIMAL; KIDNEY FAILURE, CHRONIC; MALE; PREDICTIVE VALUE OF TESTS; RATS; RATS, WISTAR; REPRODUCIBILITY OF RESULTS; SPECTROPHOTOMETRY, ATOMIC; STAINING AND LABELING; TIME FACTORS; X-RAY MICROTOMOGRAPHY;

EID: 67849109984     PISSN: 15695794     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10554-009-9459-9     Document Type: Article

References (20)

1. Davis GR, Wong FSL (1996) X-ray microtomography of bones and teeth. Physiol Meas 17:121-146. doi: 10.1088/0967-3334/17/3/001
2. Paulus MJ, Gleason SS, Kennel SJ, Hunsicker PR, Johnson DK (2000) High resolution X-ray computed tomography: An emerging tool for small animal cancer research. Neoplasia 2:62-70. doi: 10.1038/sj.neo.7900069
3. Ritman EL (2002) Molecular imaging in small animals: Roles for μ-CT. J Cell Biochem 39(Supp):116-124. doi: 10.1002/jcb.10415
4. Namati E, Chon D, Thiesse J, Hoffman EA, de Ryk J, Ross A, McLennan G (2006) In vivo μ-CT lung imaging via a computer-controlled intermittent iso-pressure hold (IIBBH) technique. Phys Med Biol 51(23):6061-6075. doi: 10.1088/0031-9155/51/23/008
5. Maréchal M, Luyten F, Nijs J, Postnov A, Schepers E, van Steenberghe D (2006) Histomorphometry and micro-computed tomography of bone augmentation under a titanium membrane. Clin Oral Implants Res 16(6):708-714. doi: 10.1111/j.1600-0501.2005.01205.x
6. De Clerck NM, Meurrens K, Weiler H, Van Dyck D, Vanhoutte G, Terpstra P, Postnov AA (2004) High resolution X-ray microtomography for the detection of lung tumors in living mice. Neoplasia 6:374-379. doi: 10.1593/neo.03481
7. Postnov A, Meurrens K, Weiler H, Van Dyck D, Xu H, Terpstra P, De Clerck NM (2005) In vivo assessment of emphysema in mice by high resolution X-ray microtomography. J Microsc 220:70-75. doi: 10.1111/ j.1365-2818.2005.01510.x
8. Waarsing JH, Day JS, van der Linden JC, Ederveen AG, Spanjers C, De Clerck N, Sasov A, Weinans H (2004) Detecting and tracking local changes in the tibiae of individual rats: A novel method to analyse longitudinal in vivo μ-CT data. Bone 34(1):163-169. doi: 10.1016/j.bone.2003.08.012
9. Postnov A, Zarowski A, De Clerck NM, Vanpoucke F, Offeciers W, Van Dyck D, Peeters S (2006) High Resolution M-CT scanning as innovatory tool for evaluation of the surgical positioning of cochlear implant electrodes. Acta Otolaryngol 126(5):467-474. doi: 10.1080/00016480500437377
10. Nair MK, Nair UP (2007) Digital and advanced imaging in endodontics: A review. J Endod 33(1):1-6. doi: 10.1016/j.joen.2006.08.013
11. Persy V, Postnov A, Neven E, Dams G, De Broe M, DHaese P, De Clerck NM (2006) Detection of vascular calcifications by high resolution X-ray microtomography in living rats with chronic renal failure. Arterioscler Thromb Vasc Biol 26:2110-2116
12. De Clerck N, Postnov A (2007) High resolution X-ray microtomography: applications in biomedical research. In: Tavitian B, Leroy-Willig A, Ntziachristos V (eds) International textbook of in vivo imaging in vertebrate. Wiley & Sons, London, pp 57-77
13. Katsumata K, Kusano K, Hirata M, Tsunemi K, Nagano N, Burke SK, Fukushima N (2003) Sevelamer hydrochloride prevents ectopic calcification and renal osteodystrophy in chronic renal failure rats. Kidney Int 64(2):441-450
14. Neven E, Dauwe S, De Broe ME, D'Haese PC, Persy V (2007) Endochondral bone formation is involved in media calcification in rats and in men. Kidney Int 72(5):574-581
15. Price PA, Roublick AM, Williamson MK (2006) Artery calcification in uremic rats is increased by a low protein diet and prevented by treatment with ibandronate. Kidney Int 70:1577-1583
16. Feldkamp LA, Davis LC, Kress JW (1984) Practical cone-beam algorithm. J Opt Soc Am A 1:612-619. doi: 10.1364/JOSAA.1.000612
17. Postnov A, Vinogradov A, Van Dyck D, Saveliev SV, De Clerck NM (2003) Quantitative analysis of bone mineral content by X-ray microtomography. Physiol Meas 24:165-178. doi: 10.1088/0967-3334/24/1/312
18. Langheinrich A, Bohle R, Greschus S, Hackstein G, von Gerlach S, Rau W, Hoelschermann H (2004) Ahterosclerotic lesions at micro-CT: Feasibility for analysis of coronary artery wall in autopsy specimens. Radiology 231:675-681. doi: 10.1148/radiol.2313021718
19. Barreto M, Schoenhagen P, Nair A, Amatangelo S, Milite M, Obuchowski N, Lieber M, Halliburton S (2008) Potential of dual-energy computed tomography to characterize atherosclerotic plaque: Ex vivo assessment of human coronary arteries in comparison to histology. J cardiovasc comput Tomogr 2:234-242
20. Schwarz F, Ruzzics B, Schoepf J, Bastarrika G, Chiarmida S, Abro J, Brothers Rm, Vogt S, Schmidt B, Costello P, Zwerner P (2008) Dual-energy CT of the heart - principles and protocols. Eur J Radiol 68:423-433. doi: 10.1016/j.ejrad.2008.09.010