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Volumn 60, Issue 3, 2009, Pages 308-317

Vascular effects of estrogen and progestins and risk of coronary artery disease: Importance of timing of estrogen treatment

Author keywords

Coronary artery disease; Estrogen; Hormone replacement therapy; Menopause; Progesterone

Indexed keywords

CYPROTERONE ACETATE PLUS ESTRADIOL VALERATE; ESTROGEN; GESTAGEN; MEDROXYPROGESTERONE ACETATE; NITRIC OXIDE; PROSTACYCLIN;

EID: 67849090615     PISSN: 00033197     EISSN: None     Source Type: Journal    
DOI: 10.1177/0003319708318377     Document Type: Review
Times cited : (11)

References (87)
  • 1
    • 34748888432 scopus 로고    scopus 로고
    • Deaths: Final data for 2004
    • Centers for Disease Control and Prevention National Center for Health Statistics National Vital Statistics System
    • Minirio AM, Heron MP, Murphy SL, Kochanek KD ; Centers for Disease Control and Prevention National Center for Health Statistics National Vital Statistics System. Deaths: final data for 2004. Natl Vital Stat Rep. 2007 ; 55: 1-119.
    • (2007) Natl Vital Stat Rep , vol.55 , pp. 1-119
    • Minirio, A.M.1    Heron, M.P.2    Murphy, S.L.3    Kochanek, K.D.4
  • 2
    • 16344390950 scopus 로고    scopus 로고
    • Vascular consequences of menopause and hormone therapy: Importance of timing of treatment and type of estrogen
    • Dubey RK, Imthurn B., Barton M., Jackson EK Vascular consequences of menopause and hormone therapy: importance of timing of treatment and type of estrogen. Cardiovasc Res. 2005 ; 66: 295-306.
    • (2005) Cardiovasc Res , vol.66 , pp. 295-306
    • Dubey, R.K.1    Imthurn, B.2    Barton, M.3    Jackson, E.K.4
  • 4
    • 0034687825 scopus 로고    scopus 로고
    • A prospective, observational study of postmenopausal hormone therapy and primary prevention of cardiovascular disease
    • Grodstein F., Manson JE, Colditz GA, Willett WC, Speizer FE, Stampfer MJ A prospective, observational study of postmenopausal hormone therapy and primary prevention of cardiovascular disease. Ann Intern Med. 2000 ; 133: 933-941.
    • (2000) Ann Intern Med , vol.133 , pp. 933-941
    • Grodstein, F.1    Manson, J.E.2    Colditz, G.A.3    Willett, W.C.4    Speizer, F.E.5    Stampfer, M.J.6
  • 5
    • 0026458371 scopus 로고
    • Hormone therapy to prevent disease and prolong life in postmenopausal women
    • Grady D., Rubin SM, Petitti DB, et al. Hormone therapy to prevent disease and prolong life in postmenopausal women. Ann Intern Med. 1992 ; 117: 1016-1037.
    • (1992) Ann Intern Med , vol.117 , pp. 1016-1037
    • Grady, D.1    Rubin, S.M.2    Petitti, D.B.3
  • 7
    • 0037125379 scopus 로고    scopus 로고
    • Risks and benefits of estrogen plus progestin in healthy postmenopausal women
    • Writing Group for the Women's Health Initiative Investigators
    • Rossouw JE, Anderson GL, Prentice RL, et al. Writing Group for the Women's Health Initiative Investigators. Risks and benefits of estrogen plus progestin in healthy postmenopausal women. JAMA. 2002 ; 288: 321-333.
    • (2002) JAMA , vol.288 , pp. 321-333
    • Rossouw, J.E.1    Anderson, G.L.2    Prentice, R.L.3
  • 8
    • 34548174755 scopus 로고    scopus 로고
    • What's new in hormone replacement therapy
    • Gebbie A. What's new in hormone replacement therapy. Medicine. 2007 ; 35: 529-532.
    • (2007) Medicine , vol.35 , pp. 529-532
    • Gebbie, A.1
  • 9
    • 0037142082 scopus 로고    scopus 로고
    • Protective effects of estrogen on the cardiovascular system
    • Mendelsohn ME Protective effects of estrogen on the cardiovascular system. Am J Cardiol. 2002 ; 89 (suppl): 12E - 18E.
    • (2002) Am J Cardiol. , vol.89
    • Mendelsohn, M.E.1
  • 10
    • 0042018741 scopus 로고    scopus 로고
    • Breast cancer and hormone-replacement therapy in the million women study
    • Million Women Study Collaborators
    • Million Women Study Collaborators. Breast cancer and hormone-replacement therapy in the million women study. Lancet. 2003 ; 362: 419-427.
    • (2003) Lancet , vol.362 , pp. 419-427
  • 11
    • 0028358749 scopus 로고
    • Effects of physiological levels of estrogen on coronary vasomotor function in postmenopausal women
    • Gilligan DM, Quyyumi AA, Cannon RO III. Effects of physiological levels of estrogen on coronary vasomotor function in postmenopausal women. Circulation. 1994 ; 89: 2545-2551.
    • (1994) Circulation , vol.89 , pp. 2545-2551
    • Gilligan, D.M.1    Quyyumi, A.A.2    Cannon III, R.O.3
  • 12
    • 0031024335 scopus 로고    scopus 로고
    • Differential effects of hormone-replacement therapy on endogenous nitric oxide (nitrite/nitrate) levels in postmenopausal women substituted with 17β-estradiol valerate and cyproterone acetate or medroxyprogesterone acetate
    • Imthurn B., Rosselli M., Jaeger AW, Keller PJ, Dubey RK Differential effects of hormone-replacement therapy on endogenous nitric oxide (nitrite/nitrate) levels in postmenopausal women substituted with 17β-estradiol valerate and cyproterone acetate or medroxyprogesterone acetate. J Clin Endocrinol Metab. 1997 ; 82: 388-394.
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 388-394
    • Imthurn, B.1    Rosselli, M.2    Jaeger, A.W.3    Keller, P.J.4    Dubey, R.K.5
  • 13
    • 0027962595 scopus 로고
    • Nitric oxide accounts for dose-dependent estrogen-mediated coronary relaxation after acute estrogen withdrawal
    • Collins P., Shay J., Jiang C., Moss J. Nitric oxide accounts for dose-dependent estrogen-mediated coronary relaxation after acute estrogen withdrawal. Circulation. 1994 ; 90: 1964-1968.
    • (1994) Circulation , vol.90 , pp. 1964-1968
    • Collins, P.1    Shay, J.2    Jiang, C.3    Moss, J.4
  • 14
    • 0032079436 scopus 로고    scopus 로고
    • The long-term effects of oral and transdermal postmenopausal hormone replacement therapy on nitric oxide, endothelin-1, prostacyclin, and thromboxane
    • Ylikorkala O., Cacciatore B., Paakkari I., Tikkanen MJ, Viinikka L., Toivonen J. The long-term effects of oral and transdermal postmenopausal hormone replacement therapy on nitric oxide, endothelin-1, prostacyclin, and thromboxane. Fertil Steril. 1998 ; 69: 883-888.
    • (1998) Fertil Steril , vol.69 , pp. 883-888
    • Ylikorkala, O.1    Cacciatore, B.2    Paakkari, I.3    Tikkanen, M.J.4    Viinikka, L.5    Toivonen, J.6
  • 15
    • 0030927817 scopus 로고    scopus 로고
    • Potential cellular signaling mechanism mediating upregulation of endothelial nitric oxide production by estrogen
    • Kavser K., Rubanyi GM Potential cellular signaling mechanism mediating upregulation of endothelial nitric oxide production by estrogen. J Vasc Res. 1997 ; 34: 229-236.
    • (1997) J Vasc Res , vol.34 , pp. 229-236
    • Kavser, K.1    Rubanyi, G.M.2
  • 16
    • 0029918970 scopus 로고    scopus 로고
    • Ethinylestradiol does not enhance the expression of nitric oxide synthase in bovine endothelial cells but increases the release of bioactive nitric oxide by inhibiting superoxide anion production
    • Arnal JF, Clamens S., Pechet C., et al. Ethinylestradiol does not enhance the expression of nitric oxide synthase in bovine endothelial cells but increases the release of bioactive nitric oxide by inhibiting superoxide anion production. Proc Natl Acad Sci U S A. 1996 ; 93: 4108-4113.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 4108-4113
    • Arnal, J.F.1    Clamens, S.2    Pechet, C.3
  • 17
    • 0034705168 scopus 로고    scopus 로고
    • Human vascular endothelial cells contain membrane binding sites for estradiol, which mediate rapid intracellular signaling
    • Russell KS, Haynes MP, Sinha D., Clerisme E., Bender JR Human vascular endothelial cells contain membrane binding sites for estradiol, which mediate rapid intracellular signaling. Proc Natl Acad Sci U S A. 2000 ; 97: 5930-5935.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 5930-5935
    • Russell, K.S.1    Haynes, M.P.2    Sinha, D.3    Clerisme, E.4    Bender, J.R.5
  • 18
    • 18144392728 scopus 로고    scopus 로고
    • Vascular cell signaling by membrane estrogen receptors
    • Hisamoto K., Bender JR Vascular cell signaling by membrane estrogen receptors. Steroids. 2005 ; 70: 382-387.
    • (2005) Steroids , vol.70 , pp. 382-387
    • Hisamoto, K.1    Bender, J.R.2
  • 19
    • 0037324382 scopus 로고    scopus 로고
    • Molecular basis of cell membrane estrogen receptor interaction with phosphatidylinositol 3-kinase in endothelial cells
    • Simoncini T., Rabkin E., Liao JK Molecular basis of cell membrane estrogen receptor interaction with phosphatidylinositol 3-kinase in endothelial cells. Arterioscler Thromb Vasc Biol. 2003 ; 23: 198-203.
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 198-203
    • Simoncini, T.1    Rabkin, E.2    Liao, J.K.3
  • 20
    • 21544469973 scopus 로고    scopus 로고
    • Estradiol mediated endothelial nitric oxide synthase association with heat shock protein 90 requires adenosine monophosphate-dependent protein kinase
    • Schulz E., Anter E., Zou MH, Keaney JF Jr. Estradiol mediated endothelial nitric oxide synthase association with heat shock protein 90 requires adenosine monophosphate-dependent protein kinase. Circulation. 2005 ; 111: 3473-3480.
    • (2005) Circulation , vol.111 , pp. 3473-3480
    • Schulz, E.1    Anter, E.2    Zou, M.H.3    Jr K.Jf4
  • 21
    • 0029043402 scopus 로고
    • Oestrogen relaxes human epicardial coronary arteries through non-endothelial dependent mechanisms
    • Chester AH, Jiang C., Borland JA, Yacoub M., Collins P. Oestrogen relaxes human epicardial coronary arteries through non-endothelial dependent mechanisms. Coron Artery Dis. 1995 ; 6: 417-422.
    • (1995) Coron Artery Dis , vol.6 , pp. 417-422
    • Chester, A.H.1    Jiang, C.2    Borland, J.A.3    Yacoub, M.4    Collins, P.5
  • 23
  • 24
    • 33644853185 scopus 로고    scopus 로고
    • Cyclooxygenases regulation by estradiol on endothelium
    • Hermenegildo C., Oviedo PJ, Cano A. Cyclooxygenases regulation by estradiol on endothelium. Curr Pharm Des. 2006 ; 12: 205-215.
    • (2006) Curr Pharm des , vol.12 , pp. 205-215
    • Hermenegildo, C.1    Oviedo, P.J.2    Cano, A.3
  • 25
    • 0036464193 scopus 로고    scopus 로고
    • Intima-media thickness: A new tool for diagnosis and treatment of cardiovascular risk
    • Simon A., Gariepy J., Chironi G., Megnien JL, Levenson J. Intima-media thickness: a new tool for diagnosis and treatment of cardiovascular risk. J Hypertens. 2002 ; 20: 159-169.
    • (2002) J Hypertens , vol.20 , pp. 159-169
    • Simon, A.1    Gariepy, J.2    Chironi, G.3    Megnien, J.L.4    Levenson, J.5
  • 26
    • 2442710388 scopus 로고    scopus 로고
    • Estrogen receptors in atherosclerotic human aorta: Inhibition of human vascular smooth muscle cell proliferation by estrogens
    • Nakamura Y., Suzuki Y., Miki C., et al. Estrogen receptors in atherosclerotic human aorta: inhibition of human vascular smooth muscle cell proliferation by estrogens. Mol Cell Endocrinol. 2004 ; 219: 17-26.
    • (2004) Mol Cell Endocrinol , vol.219 , pp. 17-26
    • Nakamura, Y.1    Suzuki, Y.2    Miki, C.3
  • 28
    • 0030297174 scopus 로고    scopus 로고
    • Endothelial cell injury in cardiovascular surgery: The procoagulant response
    • Boyle EM, Verrier ED, Spiess BD Endothelial cell injury in cardiovascular surgery: the procoagulant response. Ann Thorac Surg. 1996 ; 62: 1549-1557.
    • (1996) Ann Thorac Surg , vol.62 , pp. 1549-1557
    • Boyle, E.M.1    Verrier, E.D.2    Spiess, B.D.3
  • 29
    • 0031039272 scopus 로고    scopus 로고
    • Angiogenesis and the expression of vascular endothelial growth factor in endometrium and placenta
    • Torry DS, Torry RJ Angiogenesis and the expression of vascular endothelial growth factor in endometrium and placenta. Am J Reprod Immunol. 1997 ; 37: 21-29.
    • (1997) Am J Reprod Immunol , vol.37 , pp. 21-29
    • Torry, D.S.1    Torry, R.J.2
  • 30
    • 0032406244 scopus 로고    scopus 로고
    • Angiogenesis, vascular endothelial growth factor and the endometrium
    • Smith SK Angiogenesis, vascular endothelial growth factor and the endometrium. Hum Reprod Update. 1998 ; 4: 509-519.
    • (1998) Hum Reprod Update , vol.4 , pp. 509-519
    • Smith, S.K.1
  • 31
    • 0036488359 scopus 로고    scopus 로고
    • Effects of estrogen on endothelial function and angiogenesis
    • Rubanyi GM, Johns A., Kauser K. Effects of estrogen on endothelial function and angiogenesis. Vascul Pharmacol. 2002 ; 38: 89-98.
    • (2002) Vascul Pharmacol , vol.38 , pp. 89-98
    • Rubanyi, G.M.1    Johns, A.2    Kauser, K.3
  • 32
    • 28444481339 scopus 로고    scopus 로고
    • Effect of estrogen on differentiation and senescence in endothelial progenitor cells derived from bone marrow in spontaneously hypertensive rats
    • Imanishi T., Kobayashi K., Hano T., Nishio I. Effect of estrogen on differentiation and senescence in endothelial progenitor cells derived from bone marrow in spontaneously hypertensive rats. Hypertens Res. 2005 ; 28: 763-772.
    • (2005) Hypertens Res , vol.28 , pp. 763-772
    • Imanishi, T.1    Kobayashi, K.2    Hano, T.3    Nishio, I.4
  • 33
    • 24144438187 scopus 로고    scopus 로고
    • Estrogen reduces endothelial progentior cell senescence through augmentation of telomerase activity
    • Imanishi T., Kobayashi K., Hano T., Nishio I. Estrogen reduces endothelial progentior cell senescence through augmentation of telomerase activity. J Hypertens. 2005 ; 23: 1699-1706.
    • (2005) J Hypertens , vol.23 , pp. 1699-1706
    • Imanishi, T.1    Kobayashi, K.2    Hano, T.3    Nishio, I.4
  • 34
    • 37249012528 scopus 로고    scopus 로고
    • Estrogen induces endothelial progenitor cells proliferation and migration by estrogen receptors and PI3Kdependent pathways
    • Zhao X., Huang L., Yin Y., Fang Y., Zhao J., Chen J. Estrogen induces endothelial progenitor cells proliferation and migration by estrogen receptors and PI3Kdependent pathways. Microvasc Res. 2008 ; 75: 45-52.
    • (2008) Microvasc Res , vol.75 , pp. 45-52
    • Zhao, X.1    Huang, L.2    Yin, Y.3    Fang, Y.4    Zhao, J.5    Chen, J.6
  • 35
    • 0037695801 scopus 로고    scopus 로고
    • Differential effects of oral and transdermal postmenopausal estrogen replacement therapies on C-reactive protein
    • Lacut K., Oger E., Le Gal G., et al. SARAH investigators. Differential effects of oral and transdermal postmenopausal estrogen replacement therapies on C-reactive protein. Thromb Haemost. 2003 ; 90: 124-131.
    • (2003) Thromb Haemost , vol.90 , pp. 124-131
    • Lacut, K.1    Oger, E.2    Le Gal, G.3    Investigators, S.4
  • 36
    • 0030065688 scopus 로고    scopus 로고
    • Neovascular expression of E-selectin, intercellular adhesion molecule-1 and vascular cell adhesion molecule-1 in human atherosclerosis and their relation to intimal leukocyte content
    • O'Brien KD, McDonald TO, Chait A., Allen MD, Alpers CE Neovascular expression of E-selectin, intercellular adhesion molecule-1 and vascular cell adhesion molecule-1 in human atherosclerosis and their relation to intimal leukocyte content. Circulation. 1996 ; 93: 672-682.
    • (1996) Circulation , vol.93 , pp. 672-682
    • O'Brien, K.D.1    McDonald, T.O.2    Chait, A.3    Allen, M.D.4    Alpers, C.E.5
  • 37
    • 43249103370 scopus 로고    scopus 로고
    • A comparison of the short-term effects of oral conjugated equine estrogens vs transdermal estradiol on C-reactive protein, other serum markers of inflammation and other hepatic proteins in naturally menopausal women [published online ahead of print February 26, 2008]
    • Shifren JL, Rifai N., Desindes S., McIlwain M., Doros G., Mazer N. A comparison of the short-term effects of oral conjugated equine estrogens vs transdermal estradiol on C-reactive protein, other serum markers of inflammation and other hepatic proteins in naturally menopausal women [published online ahead of print February 26, 2008]. J Clin Endocrin Metab. doi:10.1210/jc.2007- 2193.
    • J Clin Endocrin Metab.
    • Shifren, J.L.1    Rifai, N.2    Desindes, S.3    McIlwain, M.4    Doros, G.5    Mazer, N.6
  • 38
    • 0034669457 scopus 로고    scopus 로고
    • Divergent effects of hormone therapy on serum markers of inflammation in postmenopausal women with coronary artery disease on appropriate medical management
    • Zanger D., Yang BK, Ardans J., et al. Divergent effects of hormone therapy on serum markers of inflammation in postmenopausal women with coronary artery disease on appropriate medical management. J Am Coll Cardiol. 2000 ; 36: 1797-1802.
    • (2000) J Am Coll Cardiol , vol.36 , pp. 1797-1802
    • Zanger, D.1    Yang, B.K.2    Ardans, J.3
  • 39
    • 0036890084 scopus 로고    scopus 로고
    • The effect of 17β-estradiol on endothelial and inflammatory markers in postmenopausal women: A randomized controlled trial
    • Störk S., von Schacky C., Angerer P. The effect of 17β-estradiol on endothelial and inflammatory markers in postmenopausal women: a randomized controlled trial. Atherosclerosis. 2002 ; 165: 301-307.
    • (2002) Atherosclerosis , vol.165 , pp. 301-307
    • Störk, S.1    Von Schacky, C.2    Angerer, P.3
  • 40
    • 0033578463 scopus 로고    scopus 로고
    • Effect of postmenopausal hormones on inflammation-sensitive proteins : ttthe Postmenopausal Estrogen/Progestins Interventions (PEPI) study
    • Cushman M., Legault C., Barrett-Connor E., et al. Effect of postmenopausal hormones on inflammation-sensitive proteins: the Postmenopausal Estrogen/Progestins Interventions (PEPI) study. Circulation. 1999 ; 100: 717-722.
    • (1999) Circulation , vol.100 , pp. 717-722
    • Cushman, M.1    Legault, C.2    Barrett-Connor, E.3
  • 41
    • 0037083957 scopus 로고    scopus 로고
    • The effect of 17β-estradiol on MCP-1 serum levels in postmenopausal women
    • Störk S., Baumann K., von Schacky C., Angerer P. The effect of 17β-estradiol on MCP-1 serum levels in postmenopausal women. Cardiovasc Res. 2002 ; 53: 642-649.
    • (2002) Cardiovasc Res , vol.53 , pp. 642-649
    • Störk, S.1    Baumann, K.2    Von Schacky, C.3    Angerer, P.4
  • 42
    • 34447282249 scopus 로고    scopus 로고
    • Estrogen effects on arteries vary with stage of reproductive life and extent of subclinical atherosclerosis progression
    • Clarkson TB Estrogen effects on arteries vary with stage of reproductive life and extent of subclinical atherosclerosis progression. Menopause. 2007 ; 14: 373-384.
    • (2007) Menopause , vol.14 , pp. 373-384
    • Clarkson, T.B.1
  • 43
    • 33746062392 scopus 로고    scopus 로고
    • The effects of various menopausal hormone therapies on markers of inflammation, coagulation, fibrinolysis, lipids, and lipoproteins in healthy postmenopausal women
    • Zegura B., Guzic-Salobir B., Sebestjen M., Keber I. The effects of various menopausal hormone therapies on markers of inflammation, coagulation, fibrinolysis, lipids, and lipoproteins in healthy postmenopausal women. Menopause. 2006 ; 13: 643-650.
    • (2006) Menopause , vol.13 , pp. 643-650
    • Zegura, B.1    Guzic-Salobir, B.2    Sebestjen, M.3    Keber, I.4
  • 44
    • 0026744467 scopus 로고
    • The inhibition of low-density lipoprotein oxidation by 17-beta estradiol
    • Rifici VA, Khachadurian AK The inhibition of low-density lipoprotein oxidation by 17-beta estradiol. Metabolism. 1992 ; 41: 1110-1114.
    • (1992) Metabolism , vol.41 , pp. 1110-1114
    • Rifici, V.A.1    Khachadurian, A.K.2
  • 45
    • 0037323371 scopus 로고    scopus 로고
    • Differential effects of oral and transdermal estradiol treatment on circulating estradiol fatty acid ester concentrations in postmenopausal women
    • Vihma V., Vehkavaara S., Yki-Järvinen H., Hohtari H., Tikkanen MJ Differential effects of oral and transdermal estradiol treatment on circulating estradiol fatty acid ester concentrations in postmenopausal women. J Clin Endocrinol Metab. 2003 ; 88: 588-593.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 588-593
    • Vihma, V.1    Vehkavaara, S.2    Yki-Järvinen, H.3    Hohtari, H.4    Tikkanen, M.J.5
  • 46
    • 33646763564 scopus 로고    scopus 로고
    • Estrogen therapy replenishes vascular tetrahydrobiopterin and reduces oxidative stress in ovariectomized rats
    • Lam KK, Lee YM, Hsiao G., Chen SY, Yen MH Estrogen therapy replenishes vascular tetrahydrobiopterin and reduces oxidative stress in ovariectomized rats. Menopause. 2006 ; 13: 294-302.
    • (2006) Menopause , vol.13 , pp. 294-302
    • Lam, K.K.1    Lee, Y.M.2    Hsiao, G.3    Chen, S.Y.4    Yen, M.H.5
  • 47
    • 23244440781 scopus 로고    scopus 로고
    • Determinants of the effect of estrogen on the progression of subclinical atherosclerosis: Estrogen in the Prevention of Atherosclerosis Trial
    • DOI 10.1097/01.GME.0000153934.76086.A4
    • Karim R., Mack WJ, Lobo R., et al. Determinants of the effect of estrogen on the progression of subclinical atherosclerosis: estrogen in the prevention of atherosclerosis trial. Menopause. 2005 ; 12: 366-373. (Pubitemid 41098649)
    • (2005) Menopause , vol.12 , Issue.4 , pp. 366-373
    • Karim, R.1    Mack, W.J.2    Lobo, R.A.3    Hwang, J.4    Liu, C.-R.5    Liu, C.-H.6    Sevanian, A.7    Hodis, H.N.8
  • 48
    • 33746862148 scopus 로고    scopus 로고
    • Meta-analysis: Effect of hormone-replacement therapy on components of the metabolic syndrome in postmenopausal women
    • Salpeter SR, Walsh JM, Ormiston TM, Greyber E., Buckley NS, Salpeter EE Meta-analysis: effect of hormone-replacement therapy on components of the metabolic syndrome in postmenopausal women. Diabetes Obes Metab. 2006 ; 8: 538-554.
    • (2006) Diabetes Obes Metab , vol.8 , pp. 538-554
    • Salpeter, S.R.1    Walsh, J.M.2    Ormiston, T.M.3    Greyber, E.4    Buckley, N.S.5    Salpeter, E.E.6
  • 49
    • 33845660469 scopus 로고    scopus 로고
    • Effects of low-dose continuous combined hormone replacement therapy on glucose homeostasis and markers of cardiovascular risk in women with type 2 diabetes
    • Kernohan AFB, Sattar N., Hilditch T., et al. Effects of low-dose continuous combined hormone replacement therapy on glucose homeostasis and markers of cardiovascular risk in women with type 2 diabetes. Clin Endocrinol. 2007 ; 66: 27-34.
    • (2007) Clin Endocrinol , vol.66 , pp. 27-34
    • Kernohan, A.F.B.1    Sattar, N.2    Hilditch, T.3
  • 50
    • 0031848636 scopus 로고    scopus 로고
    • Functional role of estrogen metabolism in target cells: Review and perspectives
    • Zhu BT, Conney AH Functional role of estrogen metabolism in target cells: review and perspectives. Carcinogenesis. 1998 ; 19: 1-37.
    • (1998) Carcinogenesis , vol.19 , pp. 1-37
    • Zhu, B.T.1    Conney, A.H.2
  • 52
    • 4644238003 scopus 로고    scopus 로고
    • Etrogen plus progestin and risk of venous thrombosis
    • Women's Health Initiative Investigators
    • Cushman M., Kuller LH, Prentice R., et al. Women's Health Initiative Investigators. Etrogen plus progestin and risk of venous thrombosis. JAMA. 2004 ; 292: 1573-1580.
    • (2004) JAMA , vol.292 , pp. 1573-1580
    • Cushman, M.1    Kuller, L.H.2    Prentice, R.3
  • 53
    • 33847116637 scopus 로고    scopus 로고
    • Hormone therapy and venous thromboembolism among postmenopausal women: Impact of the route of estrogen administration and progestogens: The ESTHER study
    • Estrogen and Thromboembolism Risk Study Group
    • Cananico M., Oger E., Plu-Bureau G., et al. Estrogen and Thromboembolism Risk Study Group. Hormone therapy and venous thromboembolism among postmenopausal women: impact of the route of estrogen administration and progestogens: the ESTHER study. Circulation. 2007 ; 115: 840-845.
    • (2007) Circulation , vol.115 , pp. 840-845
    • Cananico, M.1    Oger, E.2    Plu-Bureau, G.3
  • 54
    • 0025223339 scopus 로고
    • Inhibition of coronary artery atherosclerosis by 17-β- estradiol in ovariectomized monkeys. Lack of an effect of added progesterone
    • Adams MR, Kaplan JR, Manuck SB, et al. Inhibition of coronary artery atherosclerosis by 17-β- estradiol in ovariectomized monkeys. Lack of an effect of added progesterone. Arteriosclerosis. 1990 ; 10: 1051-1057.
    • (1990) Arteriosclerosis , vol.10 , pp. 1051-1057
    • Adams, M.R.1    Kaplan, J.R.2    Manuck, S.B.3
  • 55
    • 0031016850 scopus 로고    scopus 로고
    • Medroxyprogesterone acetate antagonizes inhibitory effects of conjugated equine estrogens on coronary artery atherosclerosis
    • Adams MR, Register TC, Golden DL, Wagner JD, Williams JK Medroxyprogesterone acetate antagonizes inhibitory effects of conjugated equine estrogens on coronary artery atherosclerosis. Arterioscler Thromb Vasc Biol. 1997 ; 17: 217-221.
    • (1997) Arterioscler Thromb Vasc Biol , vol.17 , pp. 217-221
    • Adams, M.R.1    Register, T.C.2    Golden, D.L.3    Wagner, J.D.4    Williams, J.K.5
  • 56
    • 0035181597 scopus 로고    scopus 로고
    • A comparison of tibolone and conjugated equine estrogens effects on coronary artery atherosclerosis and bone density of postmenopausal monkeys
    • Clarkson TB, Anthony MS, Wagner JD A comparison of tibolone and conjugated equine estrogens effects on coronary artery atherosclerosis and bone density of postmenopausal monkeys. J Clin Endocrinol Metab. 2001 ; 86: 5396-5404.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 5396-5404
    • Clarkson, T.B.1    Anthony, M.S.2    Wagner, J.D.3
  • 57
    • 0042093742 scopus 로고    scopus 로고
    • Estrogen plus progestin and the risk of coronary heart disease
    • Manson JE, Hsia J., Johnson KC, et al. Estrogen plus progestin and the risk of coronary heart disease. N Engl J Med. 2003 ; 349: 523-534.
    • (2003) N Engl J Med , vol.349 , pp. 523-534
    • Manson, J.E.1    Hsia, J.2    Johnson, K.C.3
  • 59
    • 32044435429 scopus 로고    scopus 로고
    • Hormone therapy and coronary heart disease: The role of time since menopause and age at hormone initiation
    • DOI 10.1089/jwh.2006.15.35
    • Grodstein F., Manson JE, Stampfer MJ Hormone therapy and coronary heart disease: the role of time since menopause and age at hormone initiation. J Women's Health. 2006 ; 15: 35-44. (Pubitemid 43192860)
    • (2006) Journal of Women's Health , vol.15 , Issue.1 , pp. 35-44
    • Grodstein, F.1    Manson, J.E.2    Stampfer, M.J.3
  • 60
    • 33746257210 scopus 로고    scopus 로고
    • Updating the EMAS 2004/2005 clinical recommendations on postmenopausal therapy following the recent publications: WHI and nurses' health study
    • Gompel A., Barlow D., Rozenberg S., Skouby SO Updating the EMAS 2004/2005 clinical recommendations on postmenopausal therapy following the recent publications: WHI and nurses' health study. Maturitas. 2006 ; 55: 1-4.
    • (2006) Maturitas , vol.55 , pp. 1-4
    • Gompel, A.1    Barlow, D.2    Rozenberg, S.3    Skouby, S.O.4
  • 61
    • 33646271366 scopus 로고    scopus 로고
    • Brief report: Coronary heart disease events associated with hormone therapy in younger and older women. A meta-analysis
    • Salpeter SR, Walsh JM, Greyber E., Salpeter EE Brief report: coronary heart disease events associated with hormone therapy in younger and older women. A meta-analysis. J Gen Intern Med. 2006 ; 21: 363-366.
    • (2006) J Gen Intern Med. , vol.21 , pp. 363-366
    • Salpeter, S.R.1    Walsh, J.M.2    Greyber, E.3    Salpeter, E.E.4
  • 62
    • 0035808009 scopus 로고    scopus 로고
    • Estrogen in the prevention of atherosclerosis: A randomized, double-blind, placebo-controlled trial
    • Hodis HN, Mack WJ, Lobo RA, et al. Estrogen in the prevention of atherosclerosis: a randomized, double-blind, placebo-controlled trial. Ann Intern Med. 2001 ; 135: 939-953.
    • (2001) Ann Intern Med , vol.135 , pp. 939-953
    • Hodis, H.N.1    MacK, W.J.2    Lobo, R.A.3
  • 63
    • 0028204074 scopus 로고
    • Variable expression of the estrogen receptor in normal and atherosclerotic coronary arteries of pre-menopausal women
    • Losordo DW, Kearney M., Kim EA, Jekanowski J., Isner JM Variable expression of the estrogen receptor in normal and atherosclerotic coronary arteries of pre-menopausal women. Circulation. 1994 ; 89: 1501-1510.
    • (1994) Circulation , vol.89 , pp. 1501-1510
    • Losordo, D.W.1    Kearney, M.2    Kim, E.A.3    Jekanowski, J.4    Isner, J.M.5
  • 64
    • 0032831285 scopus 로고    scopus 로고
    • Methylation of the estrogen receptor gene is associated with aging and atherosclerosis in the cardiovascular system
    • Post WS, Goldschmidt-Clermont PJ, Wilhide CC, et al. Methylation of the estrogen receptor gene is associated with aging and atherosclerosis in the cardiovascular system. Cardiovasc Res. 1999 ; 43: 985-991.
    • (1999) Cardiovasc Res , vol.43 , pp. 985-991
    • Post, W.S.1    Goldschmidt-Clermont, P.J.2    Wilhide, C.C.3
  • 65
    • 0242410301 scopus 로고    scopus 로고
    • Association between estrogen receptor-α gene variation and cardiovascular disease
    • Shearman AM, Cupples LA, Demissie S., et al. Association between estrogen receptor-α gene variation and cardiovascular disease. JAMA. 2003 ; 290: 2263-2270.
    • (2003) JAMA , vol.290 , pp. 2263-2270
    • Shearman, A.M.1    Cupples, L.A.2    Demissie, S.3
  • 66
    • 0033672019 scopus 로고    scopus 로고
    • Association of estrogen receptor-beta (ESR2) gene polymorphism with blood pressure
    • Ogawa S., Emi M., Shiraki M., Hosoi T., Ouchi Y., Inoue S. Association of estrogen receptor-beta (ESR2) gene polymorphism with blood pressure. J Hum Genet. 2000 ; 45: 327-330.
    • (2000) J Hum Genet , vol.45 , pp. 327-330
    • Ogawa, S.1    Emi, M.2    Shiraki, M.3    Hosoi, T.4    Ouchi, Y.5    Inoue, S.6
  • 67
    • 0031470524 scopus 로고    scopus 로고
    • Genotype distribution of estrogen receptor polymorphisms in men and postmenopausal women from healthy and coronary populations and its relation to serum lipid levels
    • Matsubara Y., Murata M., Kawano K., et al. Genotype distribution of estrogen receptor polymorphisms in men and postmenopausal women from healthy and coronary populations and its relation to serum lipid levels. Arterioscler Thromb Vasc Biol. 1997 ; 17: 3006-3012.
    • (1997) Arterioscler Thromb Vasc Biol , vol.17 , pp. 3006-3012
    • Matsubara, Y.1    Murata, M.2    Kawano, K.3
  • 68
    • 3042852097 scopus 로고    scopus 로고
    • Current controversies regarding the cardiovascular effects of hormone therapy
    • Karas RH Current controversies regarding the cardiovascular effects of hormone therapy. Clin Obstet Gynecol. 2004 ; 47: 489-499.
    • (2004) Clin Obstet Gynecol , vol.47 , pp. 489-499
    • Karas, R.H.1
  • 69
    • 0035895319 scopus 로고    scopus 로고
    • An HMG-CoA reductase inhibitor, cerivastatin, suppresses growth of macrophages expressing matrix metalloproteinases and tissue factor in vivo and in vitro
    • Aikawa M., Rabkin E., Sugiyama S., et al. An HMG-CoA reductase inhibitor, cerivastatin, suppresses growth of macrophages expressing matrix metalloproteinases and tissue factor in vivo and in vitro. Circulation. 2001 ; 103: 276-283.
    • (2001) Circulation , vol.103 , pp. 276-283
    • Aikawa, M.1    Rabkin, E.2    Sugiyama, S.3
  • 70
    • 0035916305 scopus 로고    scopus 로고
    • Statins alter smooth muscle cell accumulation and collagen content in established atheroma of watanabe heritable hyperlipidemic rabbits
    • Fukumoto Y., Libby P., Rabkin E., et al. Statins alter smooth muscle cell accumulation and collagen content in established atheroma of watanabe heritable hyperlipidemic rabbits. Circulation. 2001 ; 103: 993-999.
    • (2001) Circulation , vol.103 , pp. 993-999
    • Fukumoto, Y.1    Libby, P.2    Rabkin, E.3
  • 71
    • 0035916233 scopus 로고    scopus 로고
    • Provastatin treatment increases collagen content and decreases lipid content, inflammation, metalloproteinases, and cell death in human carotid plaques: Implications for plaque stabilization
    • Cribby M., Nordin-Fredriksson G., Shah PK, Yano J., Zhu J., Nilsson J. Provastatin treatment increases collagen content and decreases lipid content, inflammation, metalloproteinases, and cell death in human carotid plaques: implications for plaque stabilization. Circulation. 2001 ; 103: 926-933.
    • (2001) Circulation , vol.103 , pp. 926-933
    • Cribby, M.1    Nordin-Fredriksson, G.2    Shah, P.K.3    Yano, J.4    Zhu, J.5    Nilsson, J.6
  • 72
    • 0024217610 scopus 로고
    • Immunocytochemical localization of estradiol and progesterone receptors in the monkey ovary throughout the menstrual cycle
    • Hild-Petito S., Stouffer RL, Brenner RM Immunocytochemical localization of estradiol and progesterone receptors in the monkey ovary throughout the menstrual cycle. Endocrinology. 1988 ; 123: 2896-2905.
    • (1988) Endocrinology , vol.123 , pp. 2896-2905
    • Hild-Petito, S.1    Stouffer, R.L.2    Brenner, R.M.3
  • 73
    • 0036192022 scopus 로고    scopus 로고
    • Nongenomic action of progesterone in rat aorta: Role of nitric oxide and prostaglandins
    • Selles J., Polini N., Alvarez C., Massheimer V. Nongenomic action of progesterone in rat aorta: role of nitric oxide and prostaglandins. Cell Signal. 2002 ; 14: 431-436.
    • (2002) Cell Signal , vol.14 , pp. 431-436
    • Selles, J.1    Polini, N.2    Alvarez, C.3    Massheimer, V.4
  • 76
    • 8644286383 scopus 로고    scopus 로고
    • Progestins used in hormonal replacement therapy display different effects in coronary arteries from New Zealand white rabbits
    • Pedersen NG, Pedersen SH, Dalsgaard T., Lund CO, Nilas L., Ottesen B. Progestins used in hormonal replacement therapy display different effects in coronary arteries from New Zealand white rabbits. Maturitas. 2004 ; 49: 304-314.
    • (2004) Maturitas , vol.49 , pp. 304-314
    • Pedersen, N.G.1    Pedersen, S.H.2    Dalsgaard, T.3    Lund, C.O.4    Nilas, L.5    Ottesen, B.6
  • 77
    • 0346366918 scopus 로고    scopus 로고
    • MPA and postmenopausal coronary artery atherosclerosis revisited
    • Clarkson TB, Appt SE MPA and postmenopausal coronary artery atherosclerosis revisited. Steroids. 2003 ; 68: 941-951.
    • (2003) Steroids , vol.68 , pp. 941-951
    • Clarkson, T.B.1    Appt, S.E.2
  • 78
    • 9444234576 scopus 로고    scopus 로고
    • Differential signal transduction of progesterone and medroxyprogesterone acetate in human endothelial cells
    • Simoncini T., Mannella P., Fornari L., et al. Differential signal transduction of progesterone and medroxyprogesterone acetate in human endothelial cells. Endocrinology. 2004 ; 145: 5745-5756.
    • (2004) Endocrinology , vol.145 , pp. 5745-5756
    • Simoncini, T.1    Mannella, P.2    Fornari, L.3
  • 79
    • 0029851203 scopus 로고    scopus 로고
    • Medroxyprogesterone attenuates estrogen-mediated inhibition of neointima formation after balloon injury of the rat carotid artery
    • Levine RL, Chen SJ, Durand J., Chen YF, Oparil S. Medroxyprogesterone attenuates estrogen-mediated inhibition of neointima formation after balloon injury of the rat carotid artery. Circulation. 1996 ; 94: 2221-2227. (Pubitemid 26360517)
    • (1996) Circulation , vol.94 , Issue.9 , pp. 2221-2227
    • Levine, R.L.1    Chen, S.-J.2    Durand, J.3    Chen, Y.-F.4    Oparil, S.5
  • 80
    • 0035808001 scopus 로고    scopus 로고
    • Sex steroids used hormonal treatment increase vascular procoagulant activity by inducing thrombin receptor (PAR-1) expression. Role of the glucocorticoid receptor
    • Herkert O., Kuhl H., Sandow J., Busse R., Schini-Kerth VB Sex steroids used hormonal treatment increase vascular procoagulant activity by inducing thrombin receptor (PAR-1) expression. Role of the glucocorticoid receptor. Circulation. 2001 ; 104: 826-831.
    • (2001) Circulation , vol.104 , pp. 826-831
    • Herkert, O.1    Kuhl, H.2    Sandow, J.3    Busse, R.4    Schini-Kerth, V.B.5
  • 81
    • 1942439064 scopus 로고    scopus 로고
    • Pharmacological profile of progestins
    • Sitruk-Ware R. Pharmacological profile of progestins. Maturitas. 2004 ; 47: 277-283.
    • (2004) Maturitas , vol.47 , pp. 277-283
    • Sitruk-Ware, R.1
  • 82
    • 0033663674 scopus 로고    scopus 로고
    • Progestins and cardiovascular risk markers
    • Sitruk-Ware R. Progestins and cardiovascular risk markers. Steroids. 2000 ; 65: 651-658.
    • (2000) Steroids , vol.65 , pp. 651-658
    • Sitruk-Ware, R.1
  • 83
    • 77957126077 scopus 로고
    • Effects of androgen or estrogen/progestin regimens on heart disease risk factors in postmenopausal women: The postmenopausal estrogen/progestin (PEPI) trial
    • The Writing Group for the PEPI Trial
    • The Writing Group for the PEPI Trial. Effects of androgen or estrogen/progestin regimens on heart disease risk factors in postmenopausal women: the postmenopausal estrogen/progestin (PEPI) trial. JAMA. 1995 ; 273: 199-208.
    • (1995) JAMA , vol.273 , pp. 199-208
  • 84
    • 0026510929 scopus 로고
    • Comparison of transdermal and oral estrogen-progestin replacement therapy: Effects on serum lipids and lipoproteins
    • Crook D., Cust MP, Gangar KF, et al. Comparison of transdermal and oral estrogen-progestin replacement therapy: effects on serum lipids and lipoproteins. Am J Obstet Gynecol. 1992 ; 166: 950-955.
    • (1992) Am J Obstet Gynecol , vol.166 , pp. 950-955
    • Crook, D.1    Cust, M.P.2    Gangar, K.F.3
  • 86
    • 0033011026 scopus 로고    scopus 로고
    • Effects of progestins on cardiovascular diseases: The haemostatic system
    • Winkler UH Effects of progestins on cardiovascular diseases: the haemostatic system. Hum Reprod Update. 1999 ; 5: 200-204.
    • (1999) Hum Reprod Update , vol.5 , pp. 200-204
    • Winkler, U.H.1
  • 87
    • 0030786416 scopus 로고    scopus 로고
    • The postmenopausal estrogen/progestin interventions study; Primary outcomes in adherent women
    • Barrett-Connor E., Slone S., Greendale G., et al. The postmenopausal estrogen/progestin interventions study; primary outcomes in adherent women. Maturitas. 1997 ; 27: 261-274.
    • (1997) Maturitas , vol.27 , pp. 261-274
    • Barrett-Connor, E.1    Slone, S.2    Greendale, G.3


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