Microstimulation of visual cortex to restore vision

Progress in Brain Research

Volumn 175, Issue , 2009, Pages 347-375

  Tehovnik, Edward J ^a   Slocum, Warren M ^a   Smirnakis, Stelios M ^b   Tolias, Andreas S ^b  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

cortical visual prosthesis; electrical microstimulation; forelimb movements; phosphenes; rhesus monkeys; saccadic eye movements; striate cortex

Indexed keywords

BLINDNESS; COCHLEA PROSTHESIS; ELECTRIC FIELD; ELECTROSTIMULATION; EYE MOVEMENT CONTROL; NONHUMAN; PRIORITY JOURNAL; RETINA INJURY; REVIEW; RHESUS MONKEY; SACCADIC EYE MOVEMENT; STRIATE CORTEX; VISION; VISUAL CORTEX; VISUAL PROSTHESIS; VISUAL STIMULATION;

ANIMALS; BLINDNESS, CORTICAL; DISEASE MODELS, ANIMAL; ELECTRIC STIMULATION; ELECTRIC STIMULATION THERAPY; ELECTRODES, IMPLANTED; HUMANS; MACACA; PHOSPHENES; PROSTHESES AND IMPLANTS; SACCADES; VISUAL CORTEX; VISUAL PERCEPTION;

EID: 67849083475     PISSN: 00796123     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0079-6123(09)17524-6     Document Type: Review

References (184)

1. Airy H. On a distinct form of transient hemiopsia. Philosophical Transactions of the Royal Society of London 160 (1870) 247-264
2. Albrecht D.G., and Hamilton D.B. Striate cortex of monkey and cat: contrast response function. Journal of Neurophysiology 48 (1982) 217-237
3. Asanuma H., Arnold A., and Zarzecki P. Further study on the execution of pyramidal tract cells by intracortical microstimulation. Experimental Brain Research 26 (1976) 443-461
4. Bagshaw E.V., and Evans M.H. Measuring of current spread from microelectrodes when stimulating within the nervous system. Experimental Brain Research 25 (1976) 391-400
5. Bak M., Girvin J.P., Hambrecht F.T., Kufta C.V., Loeb G.E., and Schmidt E.M. Visual sensations produced by intracortical microstimulation of the human occipital cortex. Medical & Biological Engineering & Computing 28 (1990) 257-259
6. Barlow H.B. Critical limiting factors in the design of the eye and visual cortex. Proceedings of the Royal Society of London B 212 (1981) 1-34
7. Bartlett J.R., DeYoe E.A., Doty R.W., Lee B.B., Lewine J.D., Negrão N., et al. Psychophysics of electrical stimulation of striate cortex in macaques. Journal of Neurophysiology 94 (2005) 3430-3442
8. Bartlett J.R., and Doty R.W. Response of units in striate cortex of squirrel monkeys to visual and electrical stimuli. Journal of Neurophysiology 37 (1974) 621-641
9. Bartlett J.R., and Doty R.W. An exploration of the ability of macaques to detect microstimulation of striate cortex. Acta Neurobiologiae Experimentalis (Warszawa) 40 (1980) 713-728
10. Bierer J.A., and Middlebrook J.C. Auditory cortical imaging of cochlear-implant stimuli: dependence on electrical configuration. Journal of Neurophysiology 87 (2002) 478-492
11. Bierer J.A., and Middlebrook J.C. Cortical responses to cochlear implant stimulation: channel interactions. Journal of the Association for Research in Otolaryngology 5 (2004) 32-48
12. Black R.C., Clark G.M., and Patrick J.F. Current distribution measurement within the human cochlea. IEEE Transactions on Biomedical Engineering 28 (1981) 721-724
13. Boch R. Behavioral modulation of neuronal activity in monkey striate cortex: excitation in the absence of active fixation. Experimental Brain Research 64 (1986) 610-614
14. Boroojerdi B., Bushara K.O., Corwell B., Immisch I., Battaglia F., Muellbacher W., et al. Enhanced excitability of human visual cortex induced by short-term light deprivation. Cerebral Cortex 10 (2000) 529-534
15. Bradley D.C., Troyk P.R., Berg J.A., Cogan M., Erickson R., Kufta C., et al. Visuotopic mapping through multichannel stimulating implant in primate V1. Journal of Neurophysiology 93 (2005) 1659-1670
16. Brindley G.S. Sensory effects of electrical stimulation of the visual and paravisual cortex in man. In: Autrum H., Jung R., Loewenstein W.R., MacKay D.M., and Teuber H.L. (Eds). Handbook of sensory physiology, central processing of visual information (1972), Springer-Verlag Berlin, Heidelberg, Germany 585-594
17. Brindley G.S., and Lewin W.S. The sensations produced by electrical stimulation of visual cortex. Journal of Physiology (London) 196 (1968) 479-493
18. Brindley G.S., and Lewin W.S. The visual sensation produced by electrical stimulation of the medial occipital cortex. Journal of Physiology (London) 194 (1968) 54-55
19. Bruce C.J., and Goldberg M.E. Primate frontal eye field. I. Single neurons discharge before saccades. Journal of Neurophysiology 53 (1985) 603-635
20. Cha K., Horch K., and Normann R.A. Simulation of a phosphene-based visual field: visual acuity in a pixelized visual system. Annals of Biomedical Engineering 20 (1992) 439-449
21. Cha K., Horch K., and Normann R.A. Mobility performance with a pixelized visual system. Vision Research 32 (1992) 1367-1372
22. Cha K., Horch K.W., Normann R.A., and Boman D.K. Reading speed with a pixelized visual system. Journal of the Optical Society of America 9 (1992) 673-677
23. Chen L.L., and Tehovnik E.J. Cortical control of eye and head movements: integration of movements and percepts. The European Journal of Neuroscience 25 (2007) 1253-1264
24. Chen S.C., Hallum L.E., Lovell N.H., and Suaning G.J. Visual acuity measurement of prosthetic vision: a virtual-reality simulation study. Journal of Neural Engineering 2 (2005) S135-S145
25. Chen S.C., Hallum L.E., Lovell N.H., and Suaning G.J. Learning prosthetic vision: a virtual-reality study. IEEE Transactions on Neural Systems and Rehabilitation Engineering 13 (2005) 249-255
26. Chen S.C., Hallum L.E., Lovell N.H., and Suaning G.J. A quantitative analysis of head movement behaviour during visual acuity assessment under prosthetic vision simulation. Journal of Neural Engineering 4 (2007) S108-S123
27. Chen, S. C., Hallum, L. E., Suaning, G. J., & Lovell, N. H. (2006). Psychophysics of prosthetic vision: I. Visual scanning and visual acuity. In: Conference Proceedings IEEE Engineering Medicine Biological Society (vol. 1, pp. 4400-4403).
28. Chen, S. C., Lovell, N. H., & Suaning, G. J. (2004). Effects on prosthetic vision visual acuity by filtering schemes, filter-off frequency and phosphene matrix: a virtual reality simulation. In: Conference Proceedings IEEE Engineering Medicine Biological Society (vol. 6, pp. 4201-4204).
29. Chino Y.M., Kaas J.H., Smith III E.L., Langston A.L., and Cheng H. Rapid reorganization of cortical maps in adult cats following restricted deafferentation in retina. Vision Research 32 (1992) 789-796
30. Chowdhury V., Morley J.W., and Cornoneo M.T. Surface stimulation of the brain with a prototype array for a visual cortex prosthesis. Journal of Clinical Neuroscience 11 (2004) 750-755
31. Clark G.M. Cochlear implants: fundamentals and applications (2003), Springer-Verlag, New York pp. 1-830.
32. Clark G.M. The multi-channel cochlear implant: the interface between sound and the central nervous system for hearing, speech, and language in deaf people - a personal perspective. Philosophical Transactions of the Royal Society of London. Series B Biological Sciences 361 (2006) 791-810
33. Clark G.M., Nathar J.M., Kranz H.G., and Maritz J.S. A behavioral study on electrical stimulation of the cochlea and central auditory pathways of the cat. Experimental Neurology 36 (1972) 350-361
34. Cohen E.D. Prosthetic interfaces with the visual system: biological issues. Journal of Neural Engineering 4 (2007) R14-R31
35. Cowey A. Cortical maps and visual perception. The Grindley Memorial Lecture. The Quarterly Journal of Experimental Psychology 31 (1979) 1-17
36. Cowey A., and Walsh V. Magnetically induced phosphenes in sighted, blind and blindsighted observers. Neuroreport 11 (2000) 3269-3273
37. Daniel P.M., and Whitterridge D. The representation of the visual field on the cerebral cortex in monkeys. Journal of Physiology (London) 159 (1961) 203-221
38. Dagnelie G., Barnett D., Humayun M.S., and Thompson Jr. R.W. Paragraph text reading using a pixelized vision simulator: parameter dependence and task learning in free-viewing condition. Investigative Ophthalmology & Visual Science 47 (2006) 1241-1250
39. Dagnelie G., Keane P., Narla V., Yang L., Weiland J., and Humayun M. Real and virtual mobility performance in simulated prosthetic vision. Journal of Neural Engineering 4 (2007) S92-S101
40. Dahlem M.A., Engelmann R., Löwel S., and Müller S.C. Does the migraine aura reflect cortical organization?. The European Journal of Neuroscience 12 (2000) 767-770
41. Darian-Smith D., and Gilbert C.D. Topographic reorganization in the striate cortex of the adult cat and monkey is cortically mediated. Journal of Neuroscience 15 (1995) 1631-1647
42. Dassonville P., Schlag J., and Schlag-Rey M. The frontal eye field provides the goal for saccadic eye movement. Experimental Brain Research 89 (1992) 300-310
43. DeYoe E.A., Lewine J., and Doty R.W. Laminar variation in threshold for detection of electrical excitation of striate cortex in macaques. Journal of Neurophysiology 94 (2005) 3443-3450
44. Dobelle W.H. Artificial vision for the blind by connecting a television camera to the visual cortex. ASAIO Journal 46 (2000) 3-9
45. Dobelle W.H., and Mladejovsky M.G. Phosphenes produced by electrical stimulation of human occipital cortex, and their application to the development of a prosthesis for the blind. Journal of Physiology (London) 243 (1974) 553-576
46. Dobelle W.H., Mladejovsky M.G., Evens J.R., Roberts T.S., and Girvin J.P. 'Braille' reading by a blind volunteer by visual cortex stimulation. Nature 259 (1976) 111-112
47. Dobelle W.H., Mladejovsky M.G., and Girvin J.P. Artificial vision for the blind: electrical stimulation of visual cortex offers hope for a functional prosthesis. Science 183 (1974) 440-444
48. Doty R.W. Conditioned reflexes elicited by electrical stimulation of the brain in macaques. Journal of Neurophysiology 28 (1965) 623-640
49. Doty R.W. Electrical stimulation of the brain in behavioral context. Annual Review of Psychology 20 (1969) 289-320
50. Dow B.M., Snyder A.Z., Vautin R.G., and Bauer R. Magnification factor and receptive field size in foveal striate cortex of the monkey. Experimental Brain Research 44 (1981) 213-228
51. Evans J.R., Gordon J., Abramov I., Mladejovsky M.G., and Dobelle W.H. Brightness of phosphenes elicited by electrical stimulation of human visual cortex. Sensory Processes 3 (1979) 82-94
52. Felleman D.J., and Van Essen D.C. Distribution hierarchical processing in the primate cerebral cortex. Cerebral Cortex 1 (1991) 1-47
53. Fentress J.C., and Doty R.W. Effect of tetanization and enucleation upon excitability of visual pathways in squirrel monkeys and cats. Experimental Neurology 30 (1971) 535-554
54. Fritsch G., and Hitzig E. Über die electrische Erregbarkeit des Grosshirns. Archives of Anatomy and Physiology 37 (1879) 300-332
55. Fu L., Cai S., Zhang H., Hu G., and Zhang X. Psychophysics of reading with a limited number of pixels: towards the rehabilitation of reading ability with visual prosthesis. Vision Research 46 (2006) 1292-1301
56. Gallistel C.R., Shizgal P., and Yeomans J.S. A portrait of the substrate for self-stimulation. Psychological Review 88 (1981) 228-273
57. Gilbert C.D., Hirsch J.A., and Wiesel T.N. Lateral interactions in visual cortex. Cold Spring Harbor Symposia on Quantitative Biology 55 (1990) 663-677
58. Gilbert C.D., and Wiesel T.N. Morphological and intracortical projections of functionally characterized neurons in the cat visual cortex. Nature 280 (1979) 120-125
59. Gilbert C.D., and Wiesel T.N. Receptive field dynamics in adult primary visual cortex. Nature 356 (1992) 150-152
60. Girvin J.P., Evans J.R., Dobelle W.H., Mladejovsky M.G., Henderson D.C., Abramov I., et al. Electrical stimulation of human visual cortex: the effect of stimulation parameters on phosphene threshold. Sensory Processes 3 (1979) 66-81
61. Golomb B., Andersen R.A., Nakayama K., MacLeod D.I.A., and Wong A. Visual thresholds for shearing motion in monkey and man. Vision Research 25 (1985) 813-820
62. Grünbaum A.S.F., and Sherrington C.S. Observations on physiology of the cerebral cortex of some of the higher apes. Proceedings of the Royal Society of London. Series B Biological Sciences 69 (1901) 206
63. Grünbaum A.S.F., and Sherrington C.S. Observations on physiology of the cerebral cortex of anthropoid apes. Proceedings of the Royal Society of London. Series B Biological Sciences 72 (1903) 152
64. Grüsser O.-J. Light not illuminating the world: phosphenes and related phenomena. In: Grüsser O.-J., and Landis T. (Eds). Visual agnosias and other disturbances of visual perception and cognition, vision and visual dysfunction (1991), CRC, Boston, MA 158-178
65. Grüsser O.-J. Migraine phosphenes and the retino-cortical magnification factor. Vision Research 35 (1995) 1125-1134
66. Hadjikhani N., Sanchez del Rio M., Wu O., Schwartz D., Bakker D., Fischl B., et al. Mechanisms of migraine aura revealed by functional MRI in human visual cortex. Proceedings of the National Academy of Sciences of the United States of America 98 (2001) 4687-4692
67. Hall E.C., and Ciuffreda K.J. Fixational ocular motor control is plastic despite visual deprivation. Visual Neuroscience 19 (2002) 475-481
68. Han X., and Boyden E.S. Multiple-color optical activation, silencing, and desynchronization of neural activity with single spike temporal resolution. PLoS ONE 2 3 (2007) e299 10.1371/journal.pone.0000299
69. Hayes J.S., Yin V.T., Piyathaisere D., Weiland J.D., Humayun M.S., and Dagnelie G. Visually guided performance of simple tasks using prosthetic vision. Artificial Organs 27 (2003) 1016-1028
70. Heinen S.J., and Skavenski A.A. Recovery of visual responses in foveal V1 neurons following bilateral foveal lesions in adult monkey. Experimental Brain Research 83 (1991) 670-774
71. Hendry S.H., Fuchs J., DeBlas A.L., and Jones E.G. Distribution and plasticity of immunocytochemically localized GAGA A receptors in adult monkey visual cortex. Cerebral Cortex 3 (1990) 361-372
72. Horton J.C., and Hocking D.R. Monocular core zones and binocular border strips in primate striate cortex revealed by the contrasting effects of enucleation, eyelid suture, and retinal laser lesions on cytochrome oxidase activity. Journal of Neuroscience 18 (1998) 5433-5455
73. Hubel D.H., and Livingston M.S. Color and contrast sensitivity in the lateral geniculate nucleus and primary visual cortex of the macaque monkey. Journal of Neuroscience 10 (1990) 2223-2237
74. Hubel D.H., and Wiesel T.N. Receptive fields and functional architecture of monkey striate cortex. Journal of Physiology (London) 195 (1968) 215-243
75. Hubel D.H., and Wiesel T.N. Sequence regularity and geometry of orientation columns in the monkey striate cortex. The Journal of Comparative Neurology 158 (1974) 267-294
76. Hubel D.H., and Wiesel T.N. Uniformity of monkey striate cortex: a parallel relationship between field size, scatter, and magnification factor. The Journal of Comparative Neurology 158 (1974) 295-306
77. Hubel D.H., and Wiesel T.N. Functional architecture of macaque monkey visual cortex. Proceedings of the Royal Society of London B 198 (1977) 1-59
78. Huber D., Petreanu L., Ghitani N., Ranade S., Hromádka T., Mainen Z., et al. Sparse optical microstimulation in barrel cortex drives learned behaviour in freely moving mice. Nature 451 (2008) 61-64
79. Humayun M.S., de Juan Jr. E., Weiland J.D., Dagnelie G., Katona S., Greenberg R., et al. Vision Research 39 (1999) 2569-2576
80. Humayun M.S., Weiland J.D., Fujii G.Y., Greenberg R., Williamson R., Little J., et al. Visual perception in a blind subject with a chronic microelectrode retinal prosthesis. Vision Research 43 (2003) 2573-2581
81. Jacobs G.H. Comparative color vision (1981), Academic Press, New York
82. Jones E.G. GABAergic neurons and their role in cortical plasticity in primates. Cerebral Cortex 3 (1993) 361-372
83. Jones E.G., Hendry S.H.C., DeFelipe J., and Benson D.L. GABA neurons and their role in activity-dependent plasticity of adult primate visual cortex. In: Peters A., and Rockland K.S. (Eds). Cerebral cortex Vol. 10 (1994), Plenum Press, New York 61-140
84. Kaas J.H., Krubitzer L.A., Chino Y.M., Lanston A.L., Polley E.H., and Blair N. Reorganization of retinotopic cortical maps in adult mammals after lesions of the retina. Science 248 (1990) 229-231
85. Kayama Y., Riso R.R., Bartlett J.R., and Doty R.W. Luxotonic responses of units in macaque striate cortex. Journal of Neurophysiology 42 (1979) 1495-1517
86. Keating E.G., and Gooley S.G. Disconnection of parietal and occipital access to the saccadic oculomotor system. Experimental Brain Research 70 (1988) 385-398
87. Keating E.G., Gooley S.G., Pratt S.E., and Kelsey J. Removing the superior colliculus silences eye movements normally evoked from stimulation of the parietal and occipital eye fields. Brain Research 269 (1983) 145-148
88. Kofman O., and Yeomans J.S. Cholinergic antagonists in ventral tegmentum elevates thresholds for lateral hypothalamic and brainstem self-stimulation. Pharmacology, Biochemistry, and Behavior 31 (1988) 547-559
89. Kömpf D., and Piper H.-F. Eye movements and vestibulo-ocular reflex in the blind. Journal of Neurology 234 (1987) 337-341
90. Kral A., Hartmann R., Mortazavi D., and Klinke R. Spatial resolution of cochlear implants: the electrical field and excitation of auditory afferents. Hearing Research 121 (1998) 11-28
91. Lashley K.S. Patterns of cerebral integration indicated by the scotomas of migraine. Archives of Neurological Psychiatry 46 (1941) 331-339
92. Lee H.W., Hong S.B., Seo D.W., Tae W.S., and Hong S.C. Mapping of functional organization in human visual cortex. Neurology 54 (2000) 849-854
93. Leigh R.J., and Zee D.S. Eye movements of the blind. Investigative Ophthalmology & Visual Science 19 (1980) 328-331
94. Leonard R. Statistics on vision impairment: a resource manual (2002), Arlene R. Gordon Research Institute of Lighthouse International, New York pp. 1-49.
95. Levi D.M., Kein S.A., and Aitsebaomo A.P. Verneir acuity, crowding and cortical magnification. Vision Research 25 (1985) 963-977
96. Lovell, N. H., Dokos, S., Cheng, E., & Suaning, G. J. (2005). Stimulation of parallel current injection for use in visual prosthesis. In: Neural Engineering Conference Proceedings. 2nd International IEEE Engineering Medicine Biological Society (pp. 458-461). March 16-19.
97. O'Kusky J., and Colonnier M. A laminar analysis of the number of neurons, glia, and synapses in the visual cortex (area 17) of adult macaque monkeys. The Journal of Comparative Neurology 210 (1982) 278-290
98. Marg E., and Dierssen G. Reported visual percepts from stimulation of the human brain with microelectrodes during therapeutic surgery. Confined Neurology 26 (1965) 57-75
99. Maynard E.M. Visual prostheses. Annual Review of Biomedical Engineering 3 (2001) 145-168
100. Michael R.C. Columnar organization of color cells in monkey's striate cortex. Journal of Neurophysiology 46 (1981) 587-604
101. Miezin F.M., Myerson J., Julesz B., and Allman J.M. Evoked potential to dynamic random-dot correlograms in monkey and man: a test for cyclopean perception. Vision Research 21 (1981) 177-179
102. Morell F., and Naitoh P. Effect of cortical polarization on a conditioned avoidance response. Experimental Neurology 6 (1962) 507-523
103. Murphey D.K., and Maunsell J.H.R. Behavioral detection of electrical microstimulation in different cortical visual areas. Current Biology 17 (2007) 862-867
104. Nielson H.C., Knight J.M., and Porter P.B. Subcortical conditioning, generalization, and transfer. Journal of Comparative Physiological Psychology 55 (1962) 168-173
105. Penfield W., and Perot P. The brain's record of auditory and visual experience. Brain 86 (1963) 595-696
106. Penfield W., and Rasmussen T. The cerebral cortex of man (1957), Macmillan Co., New York pp. 1-248.
107. Peters A. The organization of the primary visual cortex in the macaque. In: Peters A., and Rockland K.S. (Eds). Cerebral cortex Vol. 10 (1994), Plenum Press, New York 1-35
108. Peters A., and Sethares C. Organization of pyramidal neurons in area 17 of monkey visual cortex. The Journal of Comparative Neurology 306 (1991) 1-23
109. Pezaris J.S., and Reid R.C. Demonstration of artificial visual percepts generated through thalamic microstimulation. Proceedings of the National Academy of Sciences of the United States of America 104 (2007) 7670-7675
110. Poggio G.F., and Fischer B. Binocular interaction and depth sensitivity in striate and prestriate cortex of behaving rhesus monkey. Journal of Neurophysiology 40 (1977) 1392-1405
111. Polyak S. In: Klüver H. (Ed). The vertebrate visual system (1957), University of Chicago Press, Chicago, IL
112. Porter R. Focal stimulation of the hypoglossal neurons in the cat. Journal of Physiology (London) 169 (1963) 630-640
113. Ranck Jr. J.B. Which elements are excited in electrical stimulation of mammalian central nervous system: a review. Brain Research 98 (1975) 417-440
114. Richards W. The fortification illusions of migraines. Scientific American 224 (1971) 88-95
115. Rizzo III J.F., Wyatt J., Loewenstein J., and Wyatt J. Perceptual efficacy of electrical stimulation of human retina with a microelectrode array during short-term surgical trials. Investigative Ophthalmology & Visual Science 44 (2003) 5362-5369
116. Rockel A.J., Hiorns R.W., and Powell T.P.S. The basic uniformity in structure of the neocortex. Brain 103 (1980) 221-244
117. Rosier A.M., Arckens L., Demeulemeester H., Orban G.A., Eysel U.T., Wu Y.-J., et al. Effect of sensory deafferentation on immunoreactivity of GABAergic cells and on GABA receptors in the adult cat visual cortex. The Journal of Comparative Neurology 359 (1995) 476-489
118. Rushton D.N., and Brindley G.S. Short- and long-term stability of cortical electrical phosphenes. In: Rose F.C. (Ed). Physiological aspects of clinical neurology (1977), Blackwell Scientific Publishing, London 123-153
119. Rushton D.N., and Brindley G.S. Properties of cortical electrical phosphenes. In: Cool S.J., and Smith E.L. (Eds). Frontiers in visual science (1978), Springer-Verlag, New York 574-593
120. Rutledge L.T., and Doty R.W. Surgical interference with pathways mediating responses conditioned to cortical stimulation. Experimental Neurology 6 (1962) 478-492
121. Sakakura H., and Doty R.W. EEG of striate cortex in blind monkeys: effects of eye movements and sleep. Archives Italiennes de Biologie 114 (1976) 23-48
122. Santos A., Humayun M.S., de Juan E., Greenburg R.J., Marsh M.J., Klock I.B., et al. Preservation of the inner retina in retinitis pigmentosa. Archives of Ophthalmology 115 (1997) 511-515
123. Schäfer E.A. Experiments on the electrical excitation of the cerebral cortex in the monkey. Brain 11 (1888) 1-6
124. Schiller P.H. The role of the monkey superior colliculus in eye movements and vision. Investigative Ophthalmology & Visual Science 11 (1972) 451-459
125. Schiller P.H. The effect of superior colliculus ablation on saccades elicited by cortical stimulation. Brain Research 122 (1977) 154-156
126. Schiller P.H., Finlay B.L., and Volman S.F. Quantitative studies of single-cell properties in monkey striate cortex. I. Spatiotemporal organization of receptive fields. Journal of Neurophysiology 39 (1976) 1288-1319
127. Schiller P.H., Finlay B.L., and Volman S.F. Quantitative studies of single-cell properties in monkey striate cortex. II. Orientation specificity and ocular dominance. Journal of Neurophysiology 39 (1976) 1320-1333
128. Schiller P.H., and Koerner F. Discharge characteristics of single units in superior colliculus of the alert rhesus monkey. Journal of Neurophysiology 34 (1971) 920-935
129. Schiller P.H., and Tehovnik E.J. Look and see: how the brain moves your eyes about. Progress in Brain Research 134 (2001) 127-142
130. Schiller P.H., and Tehovnik E.J. Visual prosthesis. Perception 37 (2008) 1529-1559
131. Schiller, P. H., Weiner, V. S., & Tehovnik E. J. (2005). Preliminary studies examining the feasibility of a visual prosthetic device. 1. What does a monkey see when area V1 is stimulated electrically. Society for Neuroscience Abstracts, 16.1.
132. Schlag J., Schlag-Rey M., and Dassonville P. Interactions between natural and electrically evoked saccades. II. At what time is eye position samples as a reference for the location of the target?. Experimental Brain Research 76 (1989) 548-558
133. Schlag-Rey M., Schlag J., and Shook B. Interactions between natural and electrically evoked saccades. I. Differences between sites carrying retinal error and more error signals in monkey superior colliculus. Experimental Brain Research 76 (1989) 537-547
134. Schmidt E.M., Bak M.J., Hambrecht F.T., Kufta C.V., O'Rourke D.K., and Vallabhanath P. Feasibility of a visual prosthesis for the blind based on intracortical microstimulation of the visual cortex. Brain 119 (1996) 507-522
135. Schuckman H., and Battersby W.S. Frequency specific mechanisms in learning. II. Discriminatory conditioning induced by intracortical stimulation. Journal of Neurophysiology 29 (1966) 31-43
136. Schuckman H., Kluger A., and Frumkes T.E. Stimulus generalization within the geniculostriate system of the monkey. Journal of Comparative and Physiological Psychology 73 (1970) 494-500
137. Schwartz E.L. Computational studies of the spatial architecture of primate visual cortex: columns, maps, and protomaps. In: Peters A., and Rockland K.S. (Eds). Cerebral cortex Vol. 10 (1994), Plenum Press, New York 359-411
138. Sereno M.I., Dale A.M., Reppas J.B., Kwong K.K., Belliveau J.W., Brady T.J., et al. Borders of multiple visual areas in humans revealed by functional magnetic resonance imaging. Science 268 (1995) 889-893
139. Slocum W.M., and Tehovnik E.J. Microstimulation of V1 input layers disrupts the selection and detection of visual targets by monkeys. The European Journal of Neuroscience 20 (2004) 1674-1680
140. Smirnakis S.M., Brewer A.A., Schmid M.C., Tolias A.S., Schüz A., Augath M., et al. Lack of long-term cortical reorganization after macaque retinal lesions. Nature 435 (2005) 300-307
141. Sparks D.L., Holland L.R., and Guthrie B.L. Size and distribution of movement fields in the monkey superior colliculus. Brain Research 113 (1976) 21-34
142. Sparks D.L., and Mays L.E. Movement fields of saccade-related burst neurons in the monkey superior colliculus. Brain Research 190 (1980) 39-50
143. Sparks D.L., and Mays L.E. Spatial localization of saccade targets. I. Compensation for stimulation-induced perturbations in eye position. Journal of Neurophysiology 49 (1983) 45-63
144. Stone J.L., Barlow W.E., Humayun M.S., de Juan Jr. E., and Milam A.H. Morphometric analysis of macular photoreceptor and ganglion cells in retinas with retinitis pigmentosa. Archives of Ophthalmology 110 (1992) 1634-1639
145. Stoney Jr. S.D., Thompson W.D., and Asanuma H. Excitation of pyramidal tract cells by intracortical microstimulation: effective extent of stimulating current. Journal of Neurophysiology 31 (1968) 659-669
146. Talalla A., Bullara L., and Pudenz R. Electrical stimulation of the human visual cortex. Canadian Journal of Neurological Sciences 1 (1974) 236-238
147. Talbot S.A., and Marshall W.H. Physiological studies on neural mechanisms of visual localization and discrimination. American Journal of Ophthalmology 24 (1941) 1255-1264
148. Tehovnik E.J., and Slocum W.M. Microstimulation of macaque V1 disrupts target selection: effects of stimulation polarity. Experimental Brain Research 148 (2003) 233-237
149. Tehovnik E.J., and Slocum W.M. Behavioural state affects saccades elicited electrically from neocortex. Neuroscience & Biobehavioral Reviews 28 (2004) 13-25
150. Tehovnik E.J., and Slocum W.M. Microstimulation of V1 affects the detection of visual targets: manipulation of target contrast. Experimental Brain Research 165 (2005) 205-314
151. Tehovnik E.J., and Slocum W.M. Microstimulation of V1 delays visually-guided saccades: a parametric evaluation of delay fields. Experimental Brain Research 176 (2007) 413-424
152. Tehovnik E.J., and Slocum W.M. Delaying forelimb responses by microstimulation of macaque V1. Experimental Brain Research 178 (2007) 422-426
153. Tehovnik E.J., and Slocum W.M. Phosphene induction by microstimulation of macaque V1. Brain Research Reviews 53 (2007) 337-343
154. Tehovnik E.J., and Slocum W.M. What delay fields tell us about striate cortex. Journal of Neurophysiology 98 (2007) 559-576
155. Tehovnik E.J., and Slocum W.M. Depth-dependent detection of microampere currents delivered to monkey V1. The European Journal of Neuroscience 29 (2009) 1477-1489
156. Tehovnik E.J., Slocum W.M., and Carvey C.E. Behavioural state affects saccadic eye movements evoked by microstimulation of striate cortex. The European Journal of Neuroscience 18 (2003) 969-979
157. Tehovnik E.J., Slocum W.M., Carvey C.E., and Schiller P.H. Phosphene induction and the generation of saccadic eye movements by striate cortex. Journal of Neurophysiology 93 (2005) 1-19
158. Tehovnik E.J., Slocum W.M., and Schiller P.H. Behavioural conditions affecting saccadic eye movements elicited electrically from the frontal lobes of primates. The European Journal of Neuroscience 11 (1999) 2431-2443
159. Tehovnik E.J., Slocum W.M., and Schiller P.H. Differential effects of laminar stimulation of V1 cortex on target selection by macaque monkeys. The European Journal of Neuroscience 16 (2002) 751-760
160. Tehovnik E.J., Slocum W.M., and Schiller P.H. Saccadic eye movements evoked by microstimulation of striate cortex. The European Journal of Neuroscience 17 (2003) 870-878
161. Tehovnik E.J., Slocum W.M., and Schiller P.H. Microstimulation of V1 delays the execution of visually guided saccades. The European Journal of Neuroscience 20 (2004) 264-272
162. Tehovnik E.J., Slocum W.M., and Schiller P.H. Delaying visually guided saccades by microstimulation of macaque V1: spatial properties of delay fields. The European Journal of Neuroscience 22 (2005) 2635-2643
163. Tehovnik E.J., Tolias A.S., Sultan F., Slocum W.M., and Logothetis N.K. Direct and indirect activation of cortical neurons by electrical microstimulation. Journal of Neurophysiology 96 (2006) 512-521
164. Thompson Jr. R.W., Barnett G.D., Humayun M.S., and Dagnelie G. Facial recognition using simulated prosthetic pixelized vision. Investigative Ophthalmology & Visual Science 44 (2003) 5035-5047
165. Tootell R.B.H., Switkes E., Silverman M.S., and Hamilton S.L. Functional anatomy of macaque striate cortex. II. Retinotopic organization. Journal of Neuroscience 8 (1988) 1531-1568
166. Tootell R.B.H., Tsao D., and Vanduffel W. Neuroimaging weights in: humans meet macaques in "primate" visual cortex. Journal of Neuroscience 23 (2003) 3981-3989
167. Trotter Y., Celebrini S., and Durand J.B. Evidence for implication of primate area V1 in neural 3-D spatial localization processing. Journal of Physiology (Paris) 98 (2004) 125-134
168. Troyk P., Bak M., Berg J., Bradley D., Cogan S., Erickson R., et al. A model for intracortical visual prosthesis research. Artificial Organs 27 (2003) 1005-1015
169. Van Essen D.C., Anderson C.H., and Felleman D.J. Information processing in the primate visual system: an integrated systems perspective. Science 255 (1992) 419-423
170. Veraart C., Raftopoulos C., Mortimer T., Delbeke J., Pins D., Michaux G., et al. Visual sensations produced by optic nerve stimulation using an implanted self-sizing spiral cuff electrode. Brain Research 813 (1998) 181-186
171. Veraart C., Wanet-Defalque M.-C., Gérard B., Vanlierde A., and Delbeke J. Pattern recognition with the optic nerve visual prosthesis. Artificial Organs 27 (2003) 996-1004
172. Wagman I.H. Eye movements induced by electrical stimulation of cerebrum in monkeys and their relationship to bodily movements. In: Bender M.B. (Ed). The oculomotor system (1964), Harper and Row, New York 18-39
173. Wagman I.H., Krieger H.P., and Bender M.B. Eye movements elicited by surface and depth stimulation of the occipital lobe of Macacca mulatta. The Journal of Comparative Neurology 109 (1958) 169-212
174. Walker E.A., and Weaver T.A. Ocular movements from the occipital lobe in the monkey. Journal of Neurophysiology 3 (1940) 353-357
175. Ward R., and Weiskrantz L. Impaired discrimination following polarization of striate cortex. Experimental Brain Research 9 (1969) 346-356
176. Warren D.J., Fernandez E., and Normann R.A. High-resolution spatial mapping of cat striate cortex using a 100-microelectrode array. Neuroscience 105 (2001) 19-31
177. Weiland J.D., and Humayan M.S. Past, present, and future of artificial vision. Artificial Organs 27 (2003) 961-962
178. Wilson B.S., Finley C.C., Lawson D.T., Wolford R.D., Eddingston D.K., and Rabinowitz W.M. Better speech recognition with cochlear implants. Nature 352 (1991) 236-238
179. Wurtz R.H., and Goldberg M.E. Superior colliculus cell responses related to eye movements in awake monkeys. Science 171 (1971) 82-84
180. Wurtz R.H., and Mohler C.W. Enhancement of visual responses in monkey striate cortex and frontal eye fields. Journal of Neurophysiology 39 (1976) 766-772
181. Yang Y., Cao P., Yang Y., and Wang S.-R. Corollary discharge circuits for saccadic modulation of the pigeon visual system. Nature Neuroscience 11 (2008) 595-602
182. Yeomans J.S. Electrically evoked behaviors: axons and synapses mapped with collision tests. Behavioural Brain Research 67 (1995) 121-132
183. Yeomans J.S., and Tehovnik E.J. Turning responses evoked by stimulation of visuomotor pathways. Brain Research Reviews 13 (1988) 235-259
184. Zrenner E. Will retinal implants restore vision?. Science 295 (2002) 1022-1025