MAP4K3 modulates cell death via the post-transcriptional regulation of BH3-only proteins

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 29, 2009, Pages 11978-11983

  Lam, David ^a   Dickens, David ^a   Reid, Elizabeth B ^a   Loh, Samantha H Y ^a   Moisoi, Nicoleta ^a   Martins, L Miguel ^a  

^a MRC TOXICOLOGY UNIT   (United Kingdom)

Author keywords

Apoptosis; GLK; Mitochondria; RNAi screen; Signal transduction

Indexed keywords

BIM PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE KINASE; PROTEIN BAD; PROTEIN BAX; PROTEIN KINASE; PUMA PROTEIN; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; HUMAN; HUMAN CELL; PANCREAS CANCER; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; APOPTOSIS REGULATORY PROTEINS; BCL-ASSOCIATED DEATH PROTEIN; CELL DEATH; CELL LINE; DNA DAMAGE; GENE EXPRESSION REGULATION; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MEMBRANE PROTEINS; MITOCHONDRIA; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; PANCREATIC NEOPLASMS; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

EID: 67749133996     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0900608106     Document Type: Article

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