Involvement of basal ganglia network in motor disabilities induced by typical antipsychotics

PLoS ONE

Volumn 4, Issue 7, 2009, Pages

  Chetrit, Jonathan ^a,b   Ballion, Bérangère ^a,b   Laquitaine, Steeve ^a,b   Belujon, Pauline ^a,b   Morin, Stéphanie ^a,b   Taupignon, Anne ^a,b   Bioulac, Bernard ^a,b,c   Gross, Christian E ^a,b,c   Benazzouz, Abdelhamid ^a,b,c  

^a UNIVERSITÉ DE BORDEAUX   (France)

^b CNRS   (France)

^c BORDEAUX UNIVERSITY HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

FLUPENTIXOL; NEUROLEPTIC AGENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIDROMIC STIMULATION; ARTICLE; BASAL GANGLION; BRAIN DAMAGE; BRAIN REGION; CATALEPSY; CELL POPULATION; CONTROLLED STUDY; CORPUS STRIATUM; EXTRAPYRAMIDAL SYMPTOM; GLOBUS PALLIDUS; HYPOKINESIA; MALE; MOTOR ACTIVITY; NERVE CELL; NEUROLOGIC EXAMINATION; NIGRONEOSTRIATAL SYSTEM; NONHUMAN; OPEN FIELD TEST; PATHOPHYSIOLOGY; RAT; SINGLE UNIT ACTIVITY; SUBSTANTIA NIGRA; SUBTHALAMIC NUCLEUS; ANIMAL; CHEMICALLY INDUCED DISORDER; DRUG EFFECT; EXTRAPYRAMIDAL SYNDROME; WISTAR RAT;

RATTUS;

ANIMALS; ANTIPSYCHOTIC AGENTS; BASAL GANGLIA; BASAL GANGLIA DISEASES; CORPUS STRIATUM; FLUPENTHIXOL; MALE; RATS; RATS, WISTAR;

EID: 67749116544     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0006208     Document Type: Article

References (51)

1. Ban TA, Lehmann HE (1974) Thiothixene and the thioxanthenes. Adv Biochem Psychopharmacol 9: 481-486.
2. Richelson E (1984) Neuroleptic affinities for human brain receptors and their use in predicting adverse effects. J Clin Psychiatry 45: 331-336.
3. Ruskin DN, Marshall JF (1997) Differing influences of dopamine agonists and antagonists on Fos expression in identified populations of globus pallidus neurons. Neuroscience 81: 79-92.
4. Marshall JF, Henry BL, Billings LM, Hoover BR (2001) The role of the globus pallidus D2 subfamily of dopamine receptors in pallidal immediate early gene expression. Neuroscience 105: 365-378.
5. Albin RL, Young AB, Penney JB (1989) The functional anatomy of basal ganglia disorders. Trends Neurosci 12: 366-375.
6. Alexander GE, DeLong MR, Strick PL (1986) Parallel organization of functionally segregated circuits linking basal ganglia and cortex. Annu Rev Neurosci 9: 357-381.
7. Graybiel AM (1990) Neurotransmitters and neuromodulators in the basal ganglia. Trends Neurosci 13: 244-254.
8. Gerfen CR (2000) Molecular effects of dopamine on striatal-projection pathways. Trends Neurosci 23: S64-70.
9. Ni Z, Bouali-Benazzouz R, Gao D, Benabid AL, Benazzouz A (2000) Changes in the firing pattern of globus pallidus neurons after the degeneration of nigrostriatal pathway are mediated by the subthalamic nucleus in the rat. Eur J Neurosci 12: 4338-4344.
10. Hassani OK, Mouroux M, Feger J (1996) Increased subthalamic neuronal activity after nigral dopaminergic lesion independent of disinhibition via the globus pallidus. Neuroscience 72: 105-115.
11. Paxinos G, Watson C (1996) The Rat Brain in Stereotaxic Coordinates. New York: Academic Press.
12. Hess EJ, Norman AB, Creese I (1988) Chronic treatment with dopamine receptor antagonists: behavioral and pharmacologic effects on D1 and D2 dopamine receptors. J Neurosci 8: 2361-2370.
13. Pitts SM, Horvitz JC (2000) Similar effects of D(1)/D(2) receptor blockade on feeding and locomotor behavior. Pharmacol Biochem Behav 65: 433-438.
14. Dulawa SC, Grandy DK, Low MJ, Paulus MP, Geyer MA (1999) Dopamine D4 receptor-knock-out mice exhibit reduced exploration of novel stimuli. J Neurosci 19: 9550-9556.
15. Belujon P, Bezard E, Taupignon A, Bioulac B, Benazzouz A (2007) Noradrenergic modulation of subthalamic nucleus activity: behavioral and electrophysiological evidence in intact and 6-hydroxydopamine-lesioned rats. J Neurosci 27: 9595-9606.
16. Sanberg PR, Pevsner J, Coyle JT (1984) Parametric influences on catalepsy. Psychopharmacology (Berl) 82: 406-408.
17. Wu YN, Hyland BI, Chen JJ (2007) Biomechanical and electromyogram characterization of neuroleptic-induced rigidity in the rat. Neuroscience 147: 183-196.
18. Tai CH, Boraud T, Bezard E, Bioulac B, Gross C, et al. (2003) Electrophysiological and metabolic evidence that high-frequency stimulation of the subthalamic nucleus bridles neuronal activity in the subthalamic nucleus and the substantia nigra reticulata. Faseb J 17: 1820-1830.
19. Mallet N, Ballion B, Le Moine C, Gonon F (2006) Cortical inputs and GABA interneurons imbalance projection neurons in the striatum of parkinsonian rats. J Neurosci 26: 3875-3884.
20. Mallet N, Le Moine C, Charpier S, Gonon F (2005) Feedforward inhibition of projection neurons by fast-spiking GABA interneurons in the rat striatum in vivo. J Neurosci 25: 3857-3869.
21. Kaneoke Y, Vitek JL (1996) Burst and oscillation as disparate neuronal properties. J Neurosci Methods 68: 211-223.
22. Boraud T, Bezard E, Guehl D, Bioulac B, Gross C (1998) Effects of L-DOPA on neuronal activity of the globus pallidus externalis (GPe) and globus pallidus internalis (GPi) in the MPTP-treated monkey. Brain Res 787: 157-160.
23. Fowler SC, Liao RM, Skjoldager P (1990) A new rodent model for neuroleptic-induced pseudo-parkinsonism: low doses of haloperidol increase forelimb tremor in the rat. Behav Neurosci 104: 449-456.
24. Eltayb A, Wadenberg ML, Svensson TH (2005) Enhanced cortical dopamine output and antipsychotic-like effect of raclopride with adjunctive low-dose L-dopa. Biol Psychiatry 58: 337-343.
25. Hauber W, Neuscheler P, Nagel J, Muller CE (2001) Catalepsy induced by a blockade of dopamine D1 or D2 receptors was reversed by a concomitant blockade of adenosine A(2A) receptors in the caudate-putamen of rats. Eur J Neurosci 14: 1287-1293.
26. Hauber W, Lutz S (1999) Dopamine D1 or D2 receptor blockade in the globus pallidus produces akinesia in the rat. Behav Brain Res 106: 143-150.
27. Farde L, Nordstrom AL (1992) PET analysis indicates atypical central dopamine receptor occupancy in clozapine-treated patients. Br J Psychiatry Suppl. pp 30-33.
28. Farde L, Nordstrom AL, Wiesel FA, Pauli S, Halldin C, et al. (1992) Positron emission tomographic analysis of central D1 and D2 dopamine receptor occupancy in patients treated with classical neuroleptics and clozapine. Relation to extrapyramidal side effects. Arch Gen Psychiatry 49: 538-544.
29. Farde L, Wiesel FA, Halldin C, Sedvall G (1988) Central D2-dopamine receptor occupancy in schizophrenic patients treated with antipsychotic drugs. Arch Gen Psychiatry 45: 71-76.
30. Kapur S, Zipursky R, Jones C, Remington G, Houle S (2000) Relationship between dopamine D(2) occupancy, clinical response, and side effects: a double-blind PET study of first-episode schizophrenia. Am J Psychiatry 157: 514-520.
31. Mukherjee J, Christian BT, Narayanan TK, Shi B, Mantil J (2001) Evaluation of dopamine D-2 receptor occupancy by clozapine, risperidone, and haloperidol in vivo in the rodent and nonhuman primate brain using 18F-fallypride. Neuropsychopharmacology 25: 476-488.
32. Boulay D, Depoortere R, Oblin A, Sanger DJ, Schoemaker H, et al. (2000) Haloperidol-induced catalepsy is absent in dopamine D(2), but maintained in dopamine D(3) receptor knock-out mice. Eur J Pharmacol 391: 63-73.
33. Reimold M, Solbach C, Noda S, Schaefer JE, Bartels M, et al. (2007) Occupancy of dopamine D(1), D (2) and serotonin (2A) receptors in schizophrenic patients treated with flupentixol in comparison with risperidone and haloperidol. Psychopharmacology (Berl) 190: 241-249.
34. Burbaud P, Gross C, Benazzouz A, Coussemacq M, Bioulac B (1995) Reduction of apomorphine-induced rotational behaviour by subthalamic lesion in 6-OHDA lesioned rats is associated with a normalization of firing rate and discharge pattern of pars reticulata neurons. Exp Brain Res 105: 48-58.
35. Murer MG, Riquelme LA, Tseng KY, Pazo JH (1997) Substantia nigra pars reticulata single unit activity in normal and 60HDA-lesioned rats: effects of intrastriatal apomorphine and subthalamic lesions. Synapse 27: 278-293.
36. Tseng KY, Kargieman L, Gacio S, Riquelme LA, Murer MG (2005) Consequences of partial and severe dopaminergic lesion on basal ganglia oscillatory activity and akinesia. Eur J Neurosci 22: 2579-2586.
37. DeLong MR (1990) Primate models of movement disorders of basal ganglia origin. Trends Neurosci 13: 281-285.
38. Deniau JM, Mailly P, Maurice N, Charpier S (2007) The pars reticulata of the substantia nigra: a window to basal ganglia output. Prog Brain Res 160: 151-172.
39. Feger J, Robledo P (1991) The Effects of Activation or Inhibition of the Subthalamic Nucleus on the Metabolic and Electrophysiological Activities Within the Pallidal Complex and Substantia Nigra in the Rat. Eur J Neurosci 3: 947-952.
40. Parent A, Hazrati LN (1995) Functional anatomy of the basal ganglia. II. The place of subthalamic nucleus and external pallidum in basal ganglia circuitry. Brain Res Brain Res Rev 20: 128-154.
41. Smith Y, Bolam JP (1990) The output neurones and the dopaminergic neurones of the substantia nigra receive a GABA-containing input from the globus pallidus in the rat. J Comp Neurol 296: 47-64.
42. Delfs JM, Anegawa NJ, Chesselet MF (1995) Glutamate decarboxylase messenger RNA in rat pallidum: comparison of the effects of haloperidol, clozapine and combined haloperidol-scopolamine treatments. Neuroscience 66: 67-80.
43. Smith Y, Bolam JP (1989) Neurons of the substantia nigra reticulata receive a dense GABA-containing input from the globus pallidus in the rat. Brain Res 493: 160-167.
44. Fujimoto K, Kita H (1992) Responses of rat substantia nigra pars reticulata units to cortical stimulation. Neurosci Lett 142: 105-109.
45. Tepper JM, Koos T, Wilson CJ (2004) GABAergic microcircuits in the neostriatum. Trends Neurosci 27: 662-669.
46. Billings LM, Marshall JF (2003) D2 antagonist-induced c-fos in an identified subpopulation of globus pallidus neurons by a direct intrapallidal action. Brain Res 964: 237-243.
47. Costall B, Naylor RJ, Olley JE (1972) Catalepsy and circling behaviour after intracerebral injections of neuroleptic, cholinergic and anticholinergic agents into the caudate-putamen, globus pallidus and substantia nigra of rat brain. Neuropharmacology 11: 645-663.
48. Galvan A, Floran B, Erlij D, Aceves J (2001) Intrapallidal dopamine restores motor deficits induced by 6-hydroxydopamine in the rat. J Neural Transm 108: 153-166.
49. Costall B, Olley JE (1971) Cholinergic and neuroleptic induced catalepsy: modification by lesions in the globus pallidus and substantia nigra. Neuropharmacology 10: 581-594.
50. Hauber W, Lutz S, Munkle M (1998) The effects of globus pallidus lesions on dopamine-dependent motor behaviour in rats. Neuroscience 86: 147-157.
51. Ossowska K, Smialowska M, Wolfarth S (1983) A biphasic influence of globus pallidus lesions: spontaneous catalepsy followed by anticataleptic effect. Pharmacol Biochem Behav 19: 169-176.