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Volumn 107, Issue 5, 2009, Pages 1031-1036

Activation of rapid signaling pathways does not contribute to 1α,25-dihydroxyvitamin D3-induced growth inhibition of mouse prostate epithelial progenitor cells

Author keywords

1,25 dihydroxyvitamin D; Growth inhibition; MAPK; Prostate; Protein kinase C; Vitamin D

Indexed keywords

CALCITRIOL; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN KINASE C ALPHA;

EID: 67749114325     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.22206     Document Type: Article
Times cited : (6)

References (41)
  • 1
    • 0033790293 scopus 로고    scopus 로고
    • 1,25(OH)(2)-vitamin D(3) affects the subcellular distribution of protein kinase C isoenzymes in rat duodenum: Influence of aging
    • Balogh G, Boland R, de Boland AR. 2000. 1,25(OH)(2)-vitamin D(3) affects the subcellular distribution of protein kinase C isoenzymes in rat duodenum: Influence of aging. J Cell Biochem 79:686-694.
    • (2000) J Cell Biochem , vol.79 , pp. 686-694
    • Balogh, G.1    Boland, R.2    de Boland, A.R.3
  • 2
    • 17644411110 scopus 로고    scopus 로고
    • Culture of mouse prostatic epithelial cells from genetically engineered mice
    • Barclay WW, Cramer SD. 2005. Culture of mouse prostatic epithelial cells from genetically engineered mice. Prostate 63:291-298.
    • (2005) Prostate , vol.63 , pp. 291-298
    • Barclay, W.W.1    Cramer, S.D.2
  • 3
    • 43049125543 scopus 로고    scopus 로고
    • Characterization of adult prostatic progenitor/stem cells exhibiting self-renewal and multilineage differentiation
    • Barclay WW, Axanova LS, Chen W, Romero L, Maund SL, Soker S, Lees CJ, Cramer SD. 2008. Characterization of adult prostatic progenitor/stem cells exhibiting self-renewal and multilineage differentiation. Stem Cells 26(3): 600-610.
    • (2008) Stem Cells , vol.26 , Issue.3 , pp. 600-610
    • Barclay, W.W.1    Axanova, L.S.2    Chen, W.3    Romero, L.4    Maund, S.L.5    Soker, S.6    Lees, C.J.7    Cramer, S.D.8
  • 4
    • 0028931846 scopus 로고
    • Protein kinase C and mitogen-activated protein kinase are required for 1,25-dihydroxyvitamin D3-stimulated Egr induction
    • Beno DW, Brady LM, Bissonnette M, Davis BH. 1995. Protein kinase C and mitogen-activated protein kinase are required for 1,25-dihydroxyvitamin D3-stimulated Egr induction. J Biol Chem 270:3642-3647.
    • (1995) J Biol Chem , vol.270 , pp. 3642-3647
    • Beno, D.W.1    Brady, L.M.2    Bissonnette, M.3    Davis, B.H.4
  • 5
    • 0030910440 scopus 로고    scopus 로고
    • 1,25-Dihydroxyvitamin D3 and 9-cis-retinoic acid act synergistically to inhibit the growth of LNCaP prostate cells and cause accumulation of cells in G1
    • Blutt SE, Allegretto EA, Pike JW, Weigel NL. 1997. 1,25-Dihydroxyvitamin D3 and 9-cis-retinoic acid act synergistically to inhibit the growth of LNCaP prostate cells and cause accumulation of cells in G1. Endocrinology 138: 1491-1497.
    • (1997) Endocrinology , vol.138 , pp. 1491-1497
    • Blutt, S.E.1    Allegretto, E.A.2    Pike, J.W.3    Weigel, N.L.4
  • 6
    • 0029819186 scopus 로고    scopus 로고
    • Role of the basal cells in premalignant changes of the human prostate is from a small prostate stem cell population
    • Bonkhoff H. 1996. Role of the basal cells in premalignant changes of the human prostate is from a small prostate stem cell population. Eur Urol 30(2): 201-205.
    • (1996) Eur Urol , vol.30 , Issue.2 , pp. 201-205
    • Bonkhoff, H.1
  • 7
    • 0344011652 scopus 로고    scopus 로고
    • Membrane actions of vitamin D metabolites 1alpha,25(OH)2D3 and 24R,25(OH)2D3 are retained in growth plate cartilage cells from vitamin D receptor knockout mice
    • Boyan BD, Sylvia VL, McKinney N, Schwartz Z. 2003. Membrane actions of vitamin D metabolites 1alpha,25(OH)2D3 and 24R,25(OH)2D3 are retained in growth plate cartilage cells from vitamin D receptor knockout mice. J Cell Biochem 90:1207-1223.
    • (2003) J Cell Biochem , vol.90 , pp. 1207-1223
    • Boyan, B.D.1    Sylvia, V.L.2    McKinney, N.3    Schwartz, Z.4
  • 9
    • 0035915482 scopus 로고    scopus 로고
    • The tyrosine kinase c-Src is required for 1,25(OH)2-vitamin D3 signalling to the nucleus in muscle cells
    • Buitrago C, Boland R, de Boland AR. 2001a. The tyrosine kinase c-Src is required for 1,25(OH)2-vitamin D3 signalling to the nucleus in muscle cells. Biochim Biophys Acta 1541:179-187.
    • (2001) Biochim Biophys Acta , vol.1541 , pp. 179-187
    • Buitrago, C.1    Boland, R.2    de Boland, A.R.3
  • 10
    • 0035930974 scopus 로고    scopus 로고
    • The vitamin D receptor mediates rapid changes in muscle protein tyrosine phosphorylation induced by 1,25(OH)(2)D(3)
    • Buitrago C, Vazquez G, De Boland AR, Boland R. 2001b. The vitamin D receptor mediates rapid changes in muscle protein tyrosine phosphorylation induced by 1,25(OH)(2)D(3). Biochem Biophys Res Commun 289:1150-1156.
    • (2001) Biochem Biophys Res Commun , vol.289 , pp. 1150-1156
    • Buitrago, C.1    Vazquez, G.2    De Boland, A.R.3    Boland, R.4
  • 11
    • 0034110058 scopus 로고    scopus 로고
    • Role of protein kinase C in 1,25(OH)(2)-vitamin D(3) modulation of intracellular calcium during development of skeletal muscle cells in culture
    • Capiati DA, Vazquez G, Tellez Inon MT, Boland RL. 2000. Role of protein kinase C in 1,25(OH)(2)-vitamin D(3) modulation of intracellular calcium during development of skeletal muscle cells in culture. J Cell Biochem 77: 200-212.
    • (2000) J Cell Biochem , vol.77 , pp. 200-212
    • Capiati, D.A.1    Vazquez, G.2    Tellez Inon, M.T.3    Boland, R.L.4
  • 12
    • 16544373001 scopus 로고    scopus 로고
    • Inhibition of serum-stimulated mitogen activated protein kinase by 1alpha,25(OH)2-vitamin D3 in MCF-7 breast cancer cells
    • Capiati DA, Rossi AM, Picotto G, Benassati S, Boland RL. 2004. Inhibition of serum-stimulated mitogen activated protein kinase by 1alpha,25(OH)2-vitamin D3 in MCF-7 breast cancer cells. J Cell Biochem 93:384-397.
    • (2004) J Cell Biochem , vol.93 , pp. 384-397
    • Capiati, D.A.1    Rossi, A.M.2    Picotto, G.3    Benassati, S.4    Boland, R.L.5
  • 13
    • 0033544896 scopus 로고    scopus 로고
    • 1,25-Dihydroxyvitamin D(3) stimulates activator protein-1-dependent Caco-2 cell differentiation
    • Chen A, Davis BH, Bissonnette M, Scaglione-Sewell B, Brasitus TA. 1999. 1,25-Dihydroxyvitamin D(3) stimulates activator protein-1-dependent Caco-2 cell differentiation. J Biol Chem 274:35505-35513.
    • (1999) J Biol Chem , vol.274 , pp. 35505-35513
    • Chen, A.1    Davis, B.H.2    Bissonnette, M.3    Scaglione-Sewell, B.4    Brasitus, T.A.5
  • 14
    • 33746602793 scopus 로고    scopus 로고
    • Modulation of MAPK ERK1 and ERK2 in VDR-positive and -negative breast cancer cell lines
    • Cordes T, Diesing D, Becker S, Diedrich K, Reichrath J, Friedrich M. 2006. Modulation of MAPK ERK1 and ERK2 in VDR-positive and -negative breast cancer cell lines. Anticancer Res 26(4A): 2749-2753.
    • (2006) Anticancer Res , vol.26 , Issue.4 A , pp. 2749-2753
    • Cordes, T.1    Diesing, D.2    Becker, S.3    Diedrich, K.4    Reichrath, J.5    Friedrich, M.6
  • 15
    • 0345599864 scopus 로고    scopus 로고
    • Steroid hormone interactions with target cells: Cross talk between membrane and nuclear pathways
    • Farach-Carson MC, Davis PJ. 2003. Steroid hormone interactions with target cells: Cross talk between membrane and nuclear pathways. J Pharmacol Exp Ther 307:839-845.
    • (2003) J Pharmacol Exp Ther , vol.307 , pp. 839-845
    • Farach-Carson, M.C.1    Davis, P.J.2
  • 17
    • 8344254362 scopus 로고    scopus 로고
    • The vitamin D receptor is present in caveolae-enriched plasma membranes and binds 1 alpha,25(OH)2-vitamin D3 in vivo and in vitro
    • Huhtakangas JA, Olivera CJ, Bishop JE, Zanello LP, Norman AW. 2004. The vitamin D receptor is present in caveolae-enriched plasma membranes and binds 1 alpha,25(OH)2-vitamin D3 in vivo and in vitro. Mol Endocrinol 18: 2660-2671.
    • (2004) Mol Endocrinol , vol.18 , pp. 2660-2671
    • Huhtakangas, J.A.1    Olivera, C.J.2    Bishop, J.E.3    Zanello, L.P.4    Norman, A.W.5
  • 18
    • 0037378429 scopus 로고    scopus 로고
    • 1alpha,25-dihydroxyvitamin D3 stimulates activator protein 1 DNA-binding activity by a phosphatidylinositol 3-kinase/Ras/MEK/ extracellular signal regulated kinase 1/2 and c-Jun N-terminal kinase 1-dependent increase in c-Fos, Fra1, and c-Jun expression in human keratinocytes
    • Johansen C, Kragballe K, Henningsen J, Westergaard M, Kristiansen K, Iversen L. 2003. 1alpha,25-dihydroxyvitamin D3 stimulates activator protein 1 DNA-binding activity by a phosphatidylinositol 3-kinase/Ras/MEK/ extracellular signal regulated kinase 1/2 and c-Jun N-terminal kinase 1-dependent increase in c-Fos, Fra1, and c-Jun expression in human keratinocytes. J Invest Dermatol 120:561-570.
    • (2003) J Invest Dermatol , vol.120 , pp. 561-570
    • Johansen, C.1    Kragballe, K.2    Henningsen, J.3    Westergaard, M.4    Kristiansen, K.5    Iversen, L.6
  • 19
    • 34247555889 scopus 로고    scopus 로고
    • The ERp57/GRp58/1,25D3-MARRS receptor: Multiple functional roles in diverse cell systems
    • Khanal RC, Nemere I. 2007. The ERp57/GRp58/1,25D3-MARRS receptor: Multiple functional roles in diverse cell systems. Curr Med Chem 14(10): 1087-1093.
    • (2007) Curr Med Chem , vol.14 , Issue.10 , pp. 1087-1093
    • Khanal, R.C.1    Nemere, I.2
  • 20
    • 0030065422 scopus 로고    scopus 로고
    • Transcriptional activation of the Cdk inhibitor p21 by vitamin D3 leads to the induced differentiation of the myelomonocytic cell line U937
    • Liu M, Lee MH, Cohen M, Bommakanti M, Freedman LP. 1996. Transcriptional activation of the Cdk inhibitor p21 by vitamin D3 leads to the induced differentiation of the myelomonocytic cell line U937. Genes Dev 10:142-153.
    • (1996) Genes Dev , vol.10 , pp. 142-153
    • Liu, M.1    Lee, M.H.2    Cohen, M.3    Bommakanti, M.4    Freedman, L.P.5
  • 22
    • 0344301937 scopus 로고    scopus 로고
    • 1,25-Dihydroxyvitamin D3 induced activation and subsequent nuclear translocation of MAPK is upstream regulated by PKC in HL-60 cells
    • Marcinkowska E, Wiedlocha A, Radzikowski C. 1997. 1,25-Dihydroxyvitamin D3 induced activation and subsequent nuclear translocation of MAPK is upstream regulated by PKC in HL-60 cells. Biochem Biophys Res Commun 241:419-426.
    • (1997) Biochem Biophys Res Commun , vol.241 , pp. 419-426
    • Marcinkowska, E.1    Wiedlocha, A.2    Radzikowski, C.3
  • 23
    • 0026601581 scopus 로고
    • The human prostatic carcinoma cell line LNCaP expresses biologically active, specific receptors for 1 alpha,25-dihydroxyvitamin D3
    • Miller GJ, Stapleton GE, Ferrara JA, Lucia MS, Pfister S, Hedlund TE, Upadhya P. 1992. The human prostatic carcinoma cell line LNCaP expresses biologically active, specific receptors for 1 alpha,25-dihydroxyvitamin D3. Cancer Res 52:515-520.
    • (1992) Cancer Res , vol.52 , pp. 515-520
    • Miller, G.J.1    Stapleton, G.E.2    Ferrara, J.A.3    Lucia, M.S.4    Pfister, S.5    Hedlund, T.E.6    Upadhya, P.7
  • 24
    • 0035931993 scopus 로고    scopus 로고
    • The stimulation of MAP kinase by 1,25(OH)(2)-vitamin D(3) in skeletal muscle cells is mediated by protein kinase C and calcium
    • Morelli S, Buitrago C, Boland R, de Boland AR. 2001. The stimulation of MAP kinase by 1,25(OH)(2)-vitamin D(3) in skeletal muscle cells is mediated by protein kinase C and calcium. Mol Cell Endocrinol 173: 41-52.
    • (2001) Mol Cell Endocrinol , vol.173 , pp. 41-52
    • Morelli, S.1    Buitrago, C.2    Boland, R.3    de Boland, A.R.4
  • 25
    • 0347480214 scopus 로고    scopus 로고
    • Tyrosine phosphorylation signalling dependent on 1alpha,25(OH)2-vitamin D3 in rat intestinal cells: Effect of ageing
    • Pardo VG, de Boland AR. 2004. Tyrosine phosphorylation signalling dependent on 1alpha,25(OH)2-vitamin D3 in rat intestinal cells: Effect of ageing. Int J Biochem Cell Biol 36:489-504.
    • (2004) Int J Biochem Cell Biol , vol.36 , pp. 489-504
    • Pardo, V.G.1    de Boland, A.R.2
  • 26
    • 0028047731 scopus 로고
    • Antiproliferative effects of 1,25-dihydroxyvitamin D3 on primary cultures of human prostatic cells
    • Peehl DM, Skowronski RJ, Leung GK, Wong ST, Stamey TA, Feldman D. 1994. Antiproliferative effects of 1,25-dihydroxyvitamin D3 on primary cultures of human prostatic cells. Cancer Res 54:805-810.
    • (1994) Cancer Res , vol.54 , pp. 805-810
    • Peehl, D.M.1    Skowronski, R.J.2    Leung, G.K.3    Wong, S.T.4    Stamey, T.A.5    Feldman, D.6
  • 27
    • 0036792216 scopus 로고    scopus 로고
    • Genistein and vitamin D synergistically inhibit human prostatic epithelial cell growth
    • Rao A, Woodruff RD, Wade WN, Kute TE, Cramer SD. 2002. Genistein and vitamin D synergistically inhibit human prostatic epithelial cell growth. J Nutr 132:3191-3194.
    • (2002) J Nutr , vol.132 , pp. 3191-3194
    • Rao, A.1    Woodruff, R.D.2    Wade, W.N.3    Kute, T.E.4    Cramer, S.D.5
  • 28
    • 1542720378 scopus 로고    scopus 로고
    • Vitamin D receptor and p21/WAF1 are targets of genistein and 1,25-dihydroxyvitamin D3 in human prostate cancer cells
    • Rao A, Coan A, Welsh JE, Barclay WW, Koumenis C, Cramer SD. 2004. Vitamin D receptor and p21/WAF1 are targets of genistein and 1,25-dihydroxyvitamin D3 in human prostate cancer cells. Cancer Res 64: 2143-2147.
    • (2004) Cancer Res , vol.64 , pp. 2143-2147
    • Rao, A.1    Coan, A.2    Welsh, J.E.3    Barclay, W.W.4    Koumenis, C.5    Cramer, S.D.6
  • 30
    • 32644451972 scopus 로고    scopus 로고
    • Regulation of the human p21(waf1/cip1) gene promoter via multiple binding sites for p53 and the vitamin D3 receptor
    • Saramaki A, Banwell CM, Campbell MJ, Carlberg C. 2006. Regulation of the human p21(waf1/cip1) gene promoter via multiple binding sites for p53 and the vitamin D3 receptor. Nucleic Acids Res 34:543-554.
    • (2006) Nucleic Acids Res , vol.34 , pp. 543-554
    • Saramaki, A.1    Banwell, C.M.2    Campbell, M.J.3    Carlberg, C.4
  • 31
    • 0025187312 scopus 로고
    • Is vitamin D deficiency a risk factor for prostate cancer? (Hypothesis)
    • Schwartz GG, Hulka BS. 1990. Is vitamin D deficiency a risk factor for prostate cancer? (Hypothesis). Anticancer Res 10:1307-1311.
    • (1990) Anticancer Res , vol.10 , pp. 1307-1311
    • Schwartz, G.G.1    Hulka, B.S.2
  • 32
    • 85047681343 scopus 로고    scopus 로고
    • 1alpha,25-dihydroxyvitamin D(3) and 24R,25-dihydroxyvitamin D(3) modulate growth plate chondrocyte physiology via protein kinase C-dependent phosphorylation of extracellular signalregulated kinase 1/2 mitogen-activated protein kinase
    • Schwartz Z, Ehland H, Sylvia VL, Larsson D, Hardin RR, Bingham V, Lopez D, Dean DD, Boyan BD. 2002. 1alpha,25-dihydroxyvitamin D(3) and 24R,25-dihydroxyvitamin D(3) modulate growth plate chondrocyte physiology via protein kinase C-dependent phosphorylation of extracellular signalregulated kinase 1/2 mitogen-activated protein kinase. Endocrinology 143:2775-2786.
    • (2002) Endocrinology , vol.143 , pp. 2775-2786
    • Schwartz, Z.1    Ehland, H.2    Sylvia, V.L.3    Larsson, D.4    Hardin, R.R.5    Bingham, V.6    Lopez, D.7    Dean, D.D.8    Boyan, B.D.9
  • 33
    • 0038205736 scopus 로고    scopus 로고
    • 1alpha,25(OH)2D3 causes a rapid increase in phosphatidylinositol-specific PLC-beta activity via phospholipase A2-dependent production of lysophospholipid
    • Schwartz Z, Shaked D, Hardin RR, Gruwell S, Dean DD, Sylvia VL, Boyan BD. 2003. 1alpha,25(OH)2D3 causes a rapid increase in phosphatidylinositol-specific PLC-beta activity via phospholipase A2-dependent production of lysophospholipid. Steroids 68:423-437.
    • (2003) Steroids , vol.68 , pp. 423-437
    • Schwartz, Z.1    Shaked, D.2    Hardin, R.R.3    Gruwell, S.4    Dean, D.D.5    Sylvia, V.L.6    Boyan, B.D.7
  • 34
    • 0027243888 scopus 로고
    • Vitamin D and prostate cancer: 1,25 dihydroxyvitamin D3 receptors and actions in human prostate cancer cell lines
    • Skowronski RJ, Peehl DM, Feldman D. 1993. Vitamin D and prostate cancer: 1,25 dihydroxyvitamin D3 receptors and actions in human prostate cancer cell lines. Endocrinology 132:1952-1960.
    • (1993) Endocrinology , vol.132 , pp. 1952-1960
    • Skowronski, R.J.1    Peehl, D.M.2    Feldman, D.3
  • 35
    • 0028982734 scopus 로고
    • Actions of vitamin D3, analogs on human prostate cancer cell lines: Comparison with 1,25-dihydroxyvitamin D3
    • Skowronski RJ, Peehl DM, Feldman D. 1995. Actions of vitamin D3, analogs on human prostate cancer cell lines: Comparison with 1,25-dihydroxyvitamin D3. Endocrinology 136:20-26.
    • (1995) Endocrinology , vol.136 , pp. 20-26
    • Skowronski, R.J.1    Peehl, D.M.2    Feldman, D.3
  • 36
    • 0031733517 scopus 로고    scopus 로고
    • Stimulation of phosphorylation of mitogen-activated protein kinase by 1alpha,25- dihydroxyvitamin D3 in promyelocytic NB4 leukemia cells: A structurefunction study
    • Song X, Bishop JE, Okamura WH, Norman AW. 1998. Stimulation of phosphorylation of mitogen-activated protein kinase by 1alpha,25- dihydroxyvitamin D3 in promyelocytic NB4 leukemia cells: A structurefunction study. Endocrinology 139:457-465.
    • (1998) Endocrinology , vol.139 , pp. 457-465
    • Song, X.1    Bishop, J.E.2    Okamura, W.H.3    Norman, A.W.4
  • 37
    • 0034837036 scopus 로고    scopus 로고
    • Regulation of proliferation of prostate epithelial cells by 1,25-dihydroxyvitamin D3 is accompanied by an increase in insulin-like growth factor binding protein-3
    • Sprenger CC, Peterson A, Lance R, Ware JL, Drivdahl RH, Plymate SR. 2001. Regulation of proliferation of prostate epithelial cells by 1,25-dihydroxyvitamin D3 is accompanied by an increase in insulin-like growth factor binding protein-3. J Endocrinol 170:609-618.
    • (2001) J Endocrinol , vol.170 , pp. 609-618
    • Sprenger, C.C.1    Peterson, A.2    Lance, R.3    Ware, J.L.4    Drivdahl, R.H.5    Plymate, S.R.6
  • 38
    • 19544391427 scopus 로고    scopus 로고
    • Role of insulin-like growth factor binding proteins in 1alpha,25-dihydroxyvitamin D(3)-induced growth inhibition of human prostate cancer cells
    • Stewart LV, Weigel NL. 2005. Role of insulin-like growth factor binding proteins in 1alpha,25-dihydroxyvitamin D(3)-induced growth inhibition of human prostate cancer cells. Prostate 64(1): 9-19.
    • (2005) Prostate , vol.64 , Issue.1 , pp. 9-19
    • Stewart, L.V.1    Weigel, N.L.2
  • 39
    • 0037369733 scopus 로고    scopus 로고
    • Vitamin D receptor is not required for the rapid actions of 1,25-dihydroxyvitamin D3 to increase intracellular calcium and activate protein kinase C in mouse osteoblasts
    • Wali RK, Kong J, Sitrin MD, Bissonnette M, Li YC. 2003. Vitamin D receptor is not required for the rapid actions of 1,25-dihydroxyvitamin D3 to increase intracellular calcium and activate protein kinase C in mouse osteoblasts. J Cell Biochem 88:794-801.
    • (2003) J Cell Biochem , vol.88 , pp. 794-801
    • Wali, R.K.1    Kong, J.2    Sitrin, M.D.3    Bissonnette, M.4    Li, Y.C.5
  • 40
    • 34447329008 scopus 로고    scopus 로고
    • 1alpha,25-Dihydroxyvitamin D(3) anti-proliferative actions involve vitamin D receptor-mediated activation of MAPK pathways and AP-1/p21(waf1) upregulation in human osteosarcoma
    • Wu W, Zhang X, Zanello LP. 2007. 1alpha,25-Dihydroxyvitamin D(3) anti-proliferative actions involve vitamin D receptor-mediated activation of MAPK pathways and AP-1/p21(waf1) upregulation in human osteosarcoma. Cancer Lett 254(1):75-86.
    • (2007) Cancer Lett , vol.254 , Issue.1 , pp. 75-86
    • Wu, W.1    Zhang, X.2    Zanello, L.P.3
  • 41
    • 85047680777 scopus 로고    scopus 로고
    • Antiproliferative effect of 1alpha,25-dihydroxyvitamin D3 in human prostate cancer cell line LNCaP involves reduction of cyclin-dependent kinase 2 activity and persistent G1 accumulation
    • Zhuang SH, Burnstein KL. 1998. Antiproliferative effect of 1alpha,25-dihydroxyvitamin D3 in human prostate cancer cell line LNCaP involves reduction of cyclin-dependent kinase 2 activity and persistent G1 accumulation. Endocrinology 139:1197-1207.
    • (1998) Endocrinology , vol.139 , pp. 1197-1207
    • Zhuang, S.H.1    Burnstein, K.L.2


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