Genistein and vitamin D synergistically inhibit human prostatic epithelial cell growth

Journal of Nutrition

Volumn 132, Issue 10, 2002, Pages 3191-3194

  Rao, Anuradha ^a   Woodruff, Ralph D ^b   Wade, Wendy N ^a   Kute, Timothy E ^b   Cramer, Scott D ^a,c  

^a Departments of General Surgery and Cancer Biology   (United States)

^b Department of Pathology ^*  (United States)

^c WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

Chemoprevention; Genistein; Prostatic epithelial cells; Synergism; Vitamin D

Indexed keywords

CALCIFEDIOL; CALCITRIOL; COLECALCIFEROL; GENISTEIN; VITAMIN D;

ARTICLE; CANCER INHIBITION; CELL CYCLE; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CONTROLLED STUDY; DRUG POTENTIATION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; MITOSIS INHIBITION; PROSTATE CANCER; PROSTATE EPITHELIUM; PROSTATE TUMOR;

EID: 0036792216     PISSN: 00223166     EISSN: None     Source Type: Journal    
DOI: 10.1093/jn/131.10.3191     Document Type: Article

References (27)

1. Breslow, N., Chan, C., Dhom, G., Drury, R., Franks, L., Gellei, B., Lee, Y., Lundberg, S., Sparke, B., Sternby, N. & Tulinius, H. (1977) Latent carcinoma of the prostate at autopsy in seven areas. Int. J. Cancer 20: 680-688.
2. Flanders, W. (1984) Review: prostate cancer epidemiology. Prostate 5: 621-629.
3. Haenszel, W. & Kurihara, M. (1968) Studies of Japanese migrants. I. Mortality from cancer and other diseases among Japanese in the United States. J. Natl. Cancer Inst. 40: 43-68.
4. Severson, R., Nomura, A., Grove, J. & Stemmermann, G. (1989) A prospective study of demographics, diet, and prostate cancer among men of Japanese ancestry in Hawaii. Cancer Res. 49: 1857-1860.
5. Adlercreutz, H. (1990) Western diet and Western diseases: some hormonal and biochemical mechanisms and associations. Scand. J. Clin. Lab. Invest. 50 (Suppl.): 3-23.
6. Schwartz, G. G. & Hulka, B. S. (1990) Is vitamin D deficiency a risk factor for prostate cancer? (Hypothesis). Anticancer Res. 10: 1307-1311.
7. Hanchette, C. L. & Schwartz, G. G. (1992) Geographic patterns of prostate cancer mortality: evidence for a protective effect of ultraviolet radiation. Cancer 70: 2861-2869.
8. Kelloff, G. (2000) Perspectives on cancer chemoprevention research and drug development. Adv. Cancer Res. 78: 199-334.
9. Polek, T. C. & Weigel, N. L. (2002) Vitamin D and prostate cancer. J. Androl. 23: 9-17.
10. Watanabe, S., Yamaguchi, M., Sobue, T., Takahashi, T., Miura, T., Arai, Y., Mazur, W., Wahala, K. & Adlercreutz, H. (1998) Pharmacokinetics of soybean isoflavones in plasma, urine and feces of men after ingestion of 60 g baked soybean powder (kinako). J. Nutr. 128: 1710-1715.
11. King, R. & Bursill, D. (1998) Plasma and urinary kinetics of the isoflavones daidzein and genistein after a single soy meal in humans. Am. J. Clin. Nutr. 67:867-872.
12. Chang, H., Churchwell, M., Delclos, K., Newbold, R. & Doerge, D. (2000) Mass spectrometric determination of genistein tissue distribution in diet-exposed Sprague-Dawley Rats. J. Nutr. 130: 1963-1970.
13. Steele, V., Pereira, M., Sigman, C. & Kelloff, G. (1995) Cancer chemoprevention agent development strategies for genistein. J. Nutr. 125: 713S-716S.
14. Peehl, D. M., Skowronski, R. J., Leung, G. K., Wong, S. T., Stamey, T. A. & Feldman, D. (1994) Antiproliferative effects of 1,25-dihydroxyvitamin D3 on primary cultures of human prostatic cells. Cancer Res. 54: 805-810.
15. Miller, G. J., Stapleton, G. E., Ferrara, J. A., Lucia, M. S., Pfister, S., Hedlund, T. E. & Upadhya, P. (1992) The human prostate carcinoma line LNCaP expresses biologically active, specific receptors for 1 a,25-dihydroxyvitamin D3. Cancer Res. 52: 515-520.
16. Skowronski, R. J., Peehl, D. M. & Feldman, D. (1993) Vitamin D and prostate cancer: 1,25 dihydroxyvitamin D3 receptors and actions in human prostate cancer cell lines. Endocrinology 132: 1952-1960.
17. Hughes, M. R., Baylink, D. J., Jones, P. G. & Haussler, M. R. (1976) Radioligand receptor assay for 25-hydroxyvitamin D2/D3 and 1α,25-dihydroxyvitamin D2/D3. J. Clin. Invest. 58: 61-70.
18. Monkawa, T., Yoshida, T., Wakino, S., Shinki, T., Anazawa, H., Deluca, H. F., Suda,T., Hayashi, M. & Saruta, T. (1997) Molecular cloning of cDNA and genomic DNA for human 25-hydroxyvitamin D3 1α-hydroxylase. Biochem. Biophys. Res. Commun. 239: 527-533.
19. Schwartz, G., Whitlatch, L., Chen, T., Lokeshwar, B. & Holick, M. (1998) Human prostate cells synthesize 1,25-dihydroxyvitamin D3 from 25-hydroxyvitamin D3. Cancer Epidemiol. Biomarkers Prev. 7: 391-395.
20. Barreto, A., Schwartz, G., Woodruff, R. & Cramer, S. (2000) 25-hydroxyvitamin D3, the prohormone of 1,25-dihydroxyvitamin D3, inhibits the proliferation of primary prostatic epithelial cells. Cancer Epidemiol. Biomarkers Prev. 9: 265-270.
21. Corder, E., Guess, H., Hulka, B., Friedman, G., Sadler, M., Vollmer, R., Lobaugh, B., Drezner, M., Vogelman, J. H. & Orentreich, N. (1993) Vitamin D and prostate cancer: a prediagnostic study with stored sera. Cancer Epidemiol. Biomarkers Prev. 2: 467-472.
22. Ahonen, M., Tenkanen, L., Teppo, M., Hakama, M. & Tuohimaa, P. (2000) Prostate cancer risk and prediagnostic serum 25-hydroxyvitamin D levels (Finland). Cancer Causes Control 11: 847-852.
23. Osborn, J., Schwartz, G., Smith, D., Bahnson, R., Day, R. & Trump, D. (1995) Phase II trial of oral 1,25-dihydroxyvitamin D3 (calcitriol) in hormone refractory prostate cancer. Urol. Oncol. 1: 195-198.
24. Gross, C., Stamey, T., Hancock, S. & Feldman, D. (1998) Treatment of early recurrent prostate cancer with 1,25-dihydroxyvitamin D3 (calcitriol). [Published erratum appears in 1998 J. Urol. 160: 840.] J. Urol. 159: 2035-2040.
25. Chou, T.-C. & Talalay, P. (1984) Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors. Adv. Enzyme Regul. 22: 27-55.
26. Preston-Martin, S., Pike, M., Ross, R. & Henderson, B. (1993) Epidemiologic evidence for the increased cell proliferation model of carcinogenesis. Environ. Health Perspect. 101 (Suppl.): 137-138.
27. Ross, R. K., Pike, M. C., Coetzee, G. A., Reichardt, J. K., Yu, M. C., Feigelson, H., Stanczyk, F. Z., Kolonel, L. N. & Henderson, B. E. (1998) Androgen metabolism and prostate cancer: establishing a model of genetic susceptibility. Cancer Res. 58: 4497-4504.