Possible mechanism for zonisamide- Induced hyperammonemia in a child with citrullinemia type 1

Indian Journal of Medical Sciences

Volumn 63, Issue 5, 2009, Pages 203-206

  Shaikh, Amir ^a,b   Muranjan, Mamta ^a   Gogtay, Nithya ^a   Lahiri, Keya ^a  

^a KEM HOSPITAL   (India)

^b NONE   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; AMMONIA; ARGININE; ASPARTATE AMINOTRANSFERASE; BENZOIC ACID; CITRULLINE; ETHOSUXIMIDE; GLUCOSE; INFUSION FLUID; LANSOPRAZOLE; ONDANSETRON; OROTIC ACID; VALPROIC ACID; ZONISAMIDE;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; AMMONIA BLOOD LEVEL; ANAMNESIS; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CASE REPORT; CHILD; CITRULLINEMIA; CLINICAL FEATURE; DRUG WITHDRAWAL; GLUCOSE BLOOD LEVEL; HUMAN; HYPERAMMONEMIA; LETTER; MALE; MASS FRAGMENTOGRAPHY; PROTEIN INTAKE; PROTEIN RESTRICTION; SCHOOL CHILD; TANDEM MASS SPECTROMETRY;

ANTICONVULSANTS; CHILD; CITRULLINEMIA; HUMANS; HYPERAMMONEMIA; ISOXAZOLES; MALE; SEIZURES;

EID: 67749095924     PISSN: 00195359     EISSN: 19983654     Source Type: Journal    
DOI: 10.4103/0019-5359.53168     Document Type: Letter

References (9)

1. Summar M. Current strategies for the management of neonatal urea cycle disorders. J Pediatr 2001;138:S30-9.
2. Dealberto MJ. Valproate-induced hyperammonaemic encephalopathy: Review of 14 cases in the psychiatric setting. Int Clin Psychopharmacol 2007;22:330-7.
3. Ambrosetto G, Riva R, Baruzzi A. Hyperammonemia in asterixis induced by carbamazepine: Two case reports. Acta Neurol Scand 1984;69:186-9.
4. Longin E, Teich M, Koelfen W, König S. Topiramate enhances the risk of valproate-associated side effects in three children. Epilepsia 2002;43:451-4.
5. Naranjo CA, Busto U, Sellers EM, Sandor P, Ruiz I, Roberts EA, et al. A method for estimating the probability of adverse drug reactions. Clin Pharmacol Ther 1981;30:239-45.
6. Chung AM, Eiland LS. Use of second-generation antiepileptic drugs in the pediatric population. Paediatr Drugs 2008;10:217-54.
7. Zonegran package insert, 2008. Available from: http://www.fda.gov/cder/ foi/ label/2006/020789s019lbl.pdf. [accessed on 2008 Sep 24].
8. Zonisamide details from World Intellectual Property Organization, 2005. Available from: http://www. wipo.int/pctdb/en/wo.jsp?WO2005070424. [accessed on 2008 Sep 25].
9. Häussinger D, Kaiser S, Stehle T, Gerok W. Liver carbonic anhydrase and urea synthesis: The effect of diuretics. Biochem Pharmacol 1986;35:3317-22.