Effect of Artemisia annua L. leaves essential oil and ethanol extract on behavioral assays

Revista Brasileira de Farmacognosia

Volumn 18, Issue SUPPL., 2008, Pages 686-689

  Perazzo, Fabio F ^a,c   Lima, Leonardo M ^c   Maistro, Edson Luis ^b   Carvalho, João E ^a   Rehder, Vera L G ^a   Carvalho, José C T ^c  

^a UNIVERSITY OF CAMPINAS   (Brazil)

^b SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

^c FEDERAL UNIVERSITY OF AMAPÁ   (Brazil)

Author keywords

Artemisia annua; Asteraceae; CNS; In vivo

Indexed keywords

ALCOHOL; ARTEMISIA ANNUA EXTRACT; CENTRAL DEPRESSANT AGENT; ESSENTIAL OIL; PENTOBARBITAL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTEMISIA ANNUA; ARTICLE; BEHAVIOR CHANGE; CONTROLLED STUDY; DEPRESSION; DISEASE MODEL; DISTILLATION; DRUG ACTIVITY; DRUG DETERMINATION; DRUG EFFECT; DRUG ISOLATION; DRUG MECHANISM; DRUG SCREENING; DRUG SYNTHESIS; EXPLORATORY BEHAVIOR; FORCED SWIMMING TEST; GROOMING; IMMOBILIZATION; MALE; MOBILIZATION; NONHUMAN; OPEN FIELD TEST; PLANT LEAF; RAT; REARING;

EID: 67749088334     PISSN: 0102695X     EISSN: None     Source Type: Journal    
DOI: 10.1590/S0102-695X2008000500008     Document Type: Article

References (19)

1. Ali BH, Bashir AK, Banna NR, Tanira MOM 1995. Central nervous system activity of Rhazya stricta Decne in mice. J Exp Pharmacol Physiol 22: 248-253.
2. Ali BH, Bashir AK, Tanira MOM 1998. The effect of Rhazya stricta Decna, a traditional medicinal plant, on the forced swimming test in rats. A new model sensitive to antidepressant treatments. Pharm Biochem Behav 59: 547-550.
3. Bartholini G, Lloyd KG, Scatton B, Zivkovic B, Morselli PL 1985. The GABA hypothesis of depression and antidepressant drug action. Psychopharmacol Bull 21: 385-387.
4. Borsini F, Evangelista S, Meli A 1986. Effect of GABAergic drugs in the behavioral despair test in rats. Eur J Pharmacol 121: 265-268.
5. Carnat AP, Gueugnot J, Lamaison JL, Guillot J, Pourrat H 1985. Ann Pharm Françaises 43: 397-405.
6. Dulawa SC, Grandy DK, Low MJ, Paulus MP, Geyer AG 1999. Dopamine D4 knock-out mice exhibited reduced exploration of novel stimuli. J Neurosci 19: 9550-9556.
7. Duncan GE, Paul IA, Harden TK, Mueller RA, Stumpf WE, Bresse GE 1985. Rapid down regulation of beta adrenergic receptors by combining antidepressants drugs with forced swim: a model of antidepressant-induced neural adaptation. J Pharmacol Exp Ther 234: 402-408.
8. Foglio MA 1996. Estudo químico da Artemisia annua L. aclimatada no Brasil. Campinas, 475p. Tese de Doutorado - Instituto de Química, Universidade Estadual de Campinas.
9. Herman ZS, Plech A, Bien E, Wieloch-Depta L, Jez W 1981. Effect of cholinomimetics, cholynolitics and atypical antidepressants in the behavioral despair test in the rat. Pol J Pharmacol Pharm 33: 485-489.
10. Kirby LG, Lucki I 1997. Interaction between the forced swimming test and fl uoxetine treatment on extracelular 5 - hydroxytryptamine and 5-hydroxyindolacetic acid in the rat. J Pharmacol Exp Ther 282: 967-976.
11. Kitada Y, Miyauchi T, Cosaza T, Satoh S 1986. The signifi cance of â- adrenoceptor down regulation in the desipramine action in the forced swimming test. NS Arch Pharmacol 333: 31-35.
12. Klayman DL 1985. Qinghaosu (artemisinin): an antimalarial drug from China. Science 228: 1049-1055.
13. Lima TCM, Morato GS, Takahashi RN 1993. Evaluation of the central properties of Artemisia verloturum. Planta Med 59: 326-329.
14. Marques DA, Foglio MA, Morgante PG, Sluys MAV, Shepherd SLK 2006. Biotechnology approaches for production of antiulcerogenic dihydro- epideoxyarteannuin B isolated from Artemisia annua L. Rev Bras Farmacogn 16: 291-299.
15. Perazzo FF, Carvalho JCT, Carvalho JE, Rehder VLG 2003. Central properties of the essential oil and the crude ethanol extract from aerial parts of Artemisia annua L. Pharmacol Res 48: 497-502.
16. Porsolt RD, LePichon M, Jalfre M 1977. Depression: a new animal model sensitive to antidepressant treatment. Nature 266: 730-732.
17. Robbers JE, Speedie MK, Tyler VE 1996. Pharmacognosy and Pharmacobiotechnology. New York: Williams & Wilkins.
18. Simon JE, Denys C, Cebert E, Grant L, Janick J, Whipkey A 1990. Artemisia annua L. A promising aromatic and medicinal. Advances in new crops: Proceedings of the First National Symposium New Crops: research, develop and economics, 522-526.
19. Sokal RR, Rohlf FJ 1995. Biometry, San Francisco: W.H. Freeman.