Multiple drug interactions - Induced serotonin syndrome: A case report

Journal of Clinical Pharmacy and Therapeutics

Volumn 34, Issue 4, 2009, Pages 485-487

  Montane E ^a,b   Barriocanal, A ^a,b   Isern, I ^a   Parajon, T ^a   Costa, J ^a,b  

^a HOSPITAL UNIVERSITARI GERMANS TRIAS I PUJOL   (Spain)

^b UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

Author keywords

Ciprofloxacin; Citalopram; Drug interaction; Fluoxetine; Reboxetine; Serotonin syndrome

Indexed keywords

ACETYLSALICYLIC ACID; CIPROFLOXACIN; CITALOPRAM; CLONAZEPAM; CYPROHEPTADINE; DIAZEPAM; ENALAPRIL; FLUOXETINE; OXYBUTYNIN; REBOXETINE; SULPIRIDE;

AGED; ANAMNESIS; ARTICLE; CASE REPORT; CLINICAL FEATURE; DEPRESSION; DRUG SAFETY; DRUG SUBSTITUTION; DRUG WITHDRAWAL; HUMAN; LABORATORY TEST; MALE; NEUROLOGIC EXAMINATION; SEROTONIN SYNDROME; SEROTONINERGIC SYSTEM; TREATMENT OUTCOME;

AGED; ANTI-INFECTIVE AGENTS; ANTIDEPRESSIVE AGENTS; CIPROFLOXACIN; DRUG INTERACTIONS; HUMANS; MALE; SEROTONIN SYNDROME; SEROTONIN UPTAKE INHIBITORS;

EID: 67651251391     PISSN: 02694727     EISSN: 13652710     Source Type: Journal    
DOI: 10.1111/j.1365-2710.2009.01023.x     Document Type: Article

References (12)

1. Isbister GK, Buckley NA, Whyte IM (2007) Serotonin toxicity: a practical approach to diagnosis and treatment. The Medical Journal of Australia, 187, 361 365.
2. Boyer EW, Shannon M (2005) The serotonin syndrome. The New England Journal of Medicine, 352, 1112 1120.
3. Brown TM, Skop BP, Mareth TR (1996) Pathophysyology and management of the serotonin syndrome. Annals of Pharmacotherapy, 30, 527 533.
4. Sternbach H (1991) The serotonin syndrome. The American Journal of Psychiatry, 148, 705 713.
5. Greenblatt DJ, Shader RI (1973) Drug Therapy. Anticholinergics. The New England Journal of Medicine, 288, 1215 1219.
6. Guzé BH, Baxter LR (1985) Current concepts. Neuroleptic malignant syndrome. The New England Journal of Medicine, 313, 165 166.
7. Hemeryck A, Belpaire FM (2002) Selective serotonin reuptake inhibitors and cytochrome P-450 mediated drug-drug interactions: an update. Current Drug Metabolism, 3, 13 37.
8. Bezchlibnyk-Butler K, Aleksic I, Kennedy SH (2000) Citalopram - a review of pharmacological and clinical effects. Journal of Psychiatry and Neuroscience, 25, 241 254.
9. Lane R, Baldwin D (1997) Selective serotonin reuptake inhibitor-induced serotonin syndrome: review. Journal of Clinical Psychopharmacology, 17, 208 221.
10. Bartolín-Guillén JM, Climent-Díaz B, Navarré-Gimeno A (2004) Serotonin syndrome due to association of venlafaxine, maprotiline and reboxetine. European Psychiatry, 19, 456 457.
11. Kuhn UD, Kirsch M, Merkel U et al. (2007) Reboxetine and cytochrome P450 - comparison with paroxetine treatment in humans. International Journal of Clinical Pharmacology and Therapeutics, 45, 36 46.
12. McLellan RA, Drobitch RK, Monshouwer M, Renton KW (1996) Fluoroquinolone antibiotics inhibit cytochrome P450-mediated microsomal drug metabolism in rat and human. Drug Metabolism and Disposition, 24, 1134 1138.