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Volumn 30, Issue 5, 1996, Pages 527-533

Pathophysiology and management of the serotonin syndrome

Author keywords

[No Author keywords available]

Indexed keywords

SEROTONIN;

EID: 0030010111     PISSN: 10600280     EISSN: None     Source Type: Journal    
DOI: 10.1177/106002809603000517     Document Type: Review
Times cited : (117)

References (61)
  • 1
    • 0000641544 scopus 로고
    • The biochemical, behavioral, and neurologic effects of high L-tryptophan intake in the rhesus monkey
    • Cruzon G, Ettlinger G, Cole M, Walsh J. The biochemical, behavioral, and neurologic effects of high L-tryptophan intake in the rhesus monkey. Neurology 1963;12:431-8.
    • (1963) Neurology , vol.12 , pp. 431-438
    • Cruzon, G.1    Ettlinger, G.2    Cole, M.3    Walsh, J.4
  • 2
    • 0025869797 scopus 로고
    • The serotonin syndrome
    • Sternbach H. The serotonin syndrome. Am J Psychiatry 1991;148:705-13.
    • (1991) Am J Psychiatry , vol.148 , pp. 705-713
    • Sternbach, H.1
  • 3
    • 0027437188 scopus 로고
    • Possible monoamine oxidase inhibitor-serotonin uptake inhibitor interaction: Fluoxetine clinical data and preclinical findings
    • Beasley CM, Masica DN, Heiligenstein JH, Wheadon DE, Zerbee RL. Possible monoamine oxidase inhibitor-serotonin uptake inhibitor interaction: fluoxetine clinical data and preclinical findings. J Clin Psychopharmacol 1993;13:312-20.
    • (1993) J Clin Psychopharmacol , vol.13 , pp. 312-320
    • Beasley, C.M.1    Masica, D.N.2    Heiligenstein, J.H.3    Wheadon, D.E.4    Zerbee, R.L.5
  • 4
    • 0024538938 scopus 로고
    • Species differences in the pharmacology of terminal autoreceptors in mammalian brain
    • Hoyer D, Middlemiss AD. Species differences in the pharmacology of terminal autoreceptors in mammalian brain. Trends Pharmacol Sci 1989;10:130-2.
    • (1989) Trends Pharmacol Sci , vol.10 , pp. 130-132
    • Hoyer, D.1    Middlemiss, A.D.2
  • 5
    • 0027339127 scopus 로고
    • 1A auto receptor blockade potentiates the ability of the 5-HT reuptake inhibitor citalopram to increase nerve terminal output of 5-HT in vivo: A microdialysis study
    • 1A auto receptor blockade potentiates the ability of the 5-HT reuptake inhibitor citalopram to increase nerve terminal output of 5-HT in vivo: a microdialysis study. J Neurochem 1993;60:776-9.
    • (1993) J Neurochem , vol.60 , pp. 776-779
    • Hjorth, S.1
  • 9
    • 0024335110 scopus 로고
    • Acetylcholine release from rat hippocampal slices is modulated by 5-hydroxytryptamine
    • Maura G, Fedele E, Raiteri M. Acetylcholine release from rat hippocampal slices is modulated by 5-hydroxytryptamine. Eur J Pharmacol 1989;165:173-9.
    • (1989) Eur J Pharmacol , vol.165 , pp. 173-179
    • Maura, G.1    Fedele, E.2    Raiteri, M.3
  • 11
    • 0026357347 scopus 로고
    • Effects of antipsychotic drugs on serotonin receptors
    • Meltzer HY, Nash JF. Effects of antipsychotic drugs on serotonin receptors. Pharmacol Rev 1991;43:587-604.
    • (1991) Pharmacol Rev , vol.43 , pp. 587-604
    • Meltzer, H.Y.1    Nash, J.F.2
  • 12
    • 0030050198 scopus 로고    scopus 로고
    • Potential bleeding and vascular complications of treatment with selective serotonin reuptake inhibitors
    • Skop BP, Brown TM, Potential bleeding and vascular complications of treatment with selective serotonin reuptake inhibitors. Psychosomatics 1996;37:12-6.
    • (1996) Psychosomatics , vol.37 , pp. 12-16
    • Skop, B.P.1    Brown, T.M.2
  • 13
    • 0026731463 scopus 로고
    • Hyperventilation-induced cerebral ischemia in panic disorder and effect of nimodipine
    • Gibbs DM. Hyperventilation-induced cerebral ischemia in panic disorder and effect of nimodipine. Am J Psychiatry 1991;149:1589-91.
    • (1991) Am J Psychiatry , vol.149 , pp. 1589-1591
    • Gibbs, D.M.1
  • 15
    • 0028046561 scopus 로고
    • The serotonin syndrome associated with paroxetine, an over-the-counter cold remedy, and vascular disease: A case report and review
    • Skop BP, Finkelstein J, Mareth TR, Magoon M, Brown TM. The serotonin syndrome associated with paroxetine, an over-the-counter cold remedy, and vascular disease: a case report and review. Am J Emerg Med 1994;12:642-4.
    • (1994) Am J Emerg Med , vol.12 , pp. 642-644
    • Skop, B.P.1    Finkelstein, J.2    Mareth, T.R.3    Magoon, M.4    Brown, T.M.5
  • 16
    • 0030065217 scopus 로고    scopus 로고
    • Nitroglycerin in the treatment of the serotonin syndrome
    • Brown TM, Skop BP. Nitroglycerin in the treatment of the serotonin syndrome (letter). Ann Pharmacother 1996;30:191.
    • (1996) Ann Pharmacother , vol.30 , pp. 191
    • Brown, T.M.1    Skop, B.P.2
  • 17
    • 0028837981 scopus 로고
    • Fluoxetine and extrapyramidal side effects
    • Coulter DM, Pillans PI. Fluoxetine and extrapyramidal side effects. Am J Psychiatry 1995;152:122-5.
    • (1995) Am J Psychiatry , vol.152 , pp. 122-125
    • Coulter, D.M.1    Pillans, P.I.2
  • 18
  • 19
    • 0016244910 scopus 로고
    • The role of berotonin in the pathophysiology of myoclonus seizures associated with acute imipramine toxicity
    • Westheimer R, Klawans HL. The role of berotonin in the pathophysiology of myoclonus seizures associated with acute imipramine toxicity. Neurology 1974;24:1175-7.
    • (1974) Neurology , vol.24 , pp. 1175-1177
    • Westheimer, R.1    Klawans, H.L.2
  • 20
    • 0023934802 scopus 로고
    • Clinical, biochemical, and pharmacological observation in a patient with postasphyxic myoclonus: Association to serotonin hyperactivity
    • Gimenez-Roldan S, Mateo D, Muradas V, De Yebens JG. Clinical, biochemical, and pharmacological observation in a patient with postasphyxic myoclonus: association to serotonin hyperactivity. Clin Neuropharmacol 1988;11:151-60
    • (1988) Clin Neuropharmacol , vol.11 , pp. 151-160
    • Gimenez-Roldan, S.1    Mateo, D.2    Muradas, V.3    De Yebens, J.G.4
  • 21
    • 0026347915 scopus 로고
    • Serotonin and behavior: Emphasis on motor control
    • Jacobs BL. Serotonin and behavior: emphasis on motor control. J Clin Psychiatry 1991;52(suppl 12): 17-23
    • (1991) J Clin Psychiatry , vol.52 , Issue.12 SUPPL. , pp. 17-23
    • Jacobs, B.L.1
  • 22
    • 0026357341 scopus 로고
    • Serotonin-selective arylpiperazines with neuroendocrine, behavioral, temperature, and cardiovascular effects in humans
    • Murphy DL, Lesch KP, Aulakh CS, Pigott TA. III. Serotonin-selective arylpiperazines with neuroendocrine, behavioral, temperature, and cardiovascular effects in humans. Pharmacol Rev 1991;43:527-52.
    • (1991) Pharmacol Rev , vol.43 , pp. 527-552
    • Murphy, D.L.1    Lesch, K.P.2    Aulakh, C.S.3    Pigott III, T.A.4
  • 23
    • 0027340595 scopus 로고
    • 2 receptor mediates serotonin-induced electrolyte transport in rat left colon
    • 2 receptor mediates serotonin-induced electrolyte transport in rat left colon. J Surg Res 1993;55:323-9.
    • (1993) J Surg Res , vol.55 , pp. 323-329
    • Siriwardena, A.1    Kellum, J.M.2
  • 24
    • 0024424733 scopus 로고
    • A microelectrode study for responses to secretogogues by epithelial cells on villus and crypt of rats' small intestine
    • Stewart CP, Turnberg LA. A microelectrode study for responses to secretogogues by epithelial cells on villus and crypt of rats' small intestine. Am J Physiol 1989;257:G334-9.
    • (1989) Am J Physiol , vol.257
    • Stewart, C.P.1    Turnberg, L.A.2
  • 25
    • 0026643829 scopus 로고
    • Changes in serotonin metabolism in cancer patients: Its relationship to nausea and vomiting induced by chemotherapeutic drugs
    • Cubeddu LX, Hoffmann IS, Fuenmayor NT, Malave JJ. Changes in serotonin metabolism in cancer patients: its relationship to nausea and vomiting induced by chemotherapeutic drugs. Br J Cancer 1992;66:198-203.
    • (1992) Br J Cancer , vol.66 , pp. 198-203
    • Cubeddu, L.X.1    Hoffmann, I.S.2    Fuenmayor, N.T.3    Malave, J.J.4
  • 26
    • 0023274497 scopus 로고
    • Serotonin receptors in the human brain. IV. Autoradiographic mapping of serotonin receptors
    • Pazos A, Probst A, Palacios JM. Serotonin receptors in the human brain. IV. Autoradiographic mapping of serotonin receptors. Neuroscience 1987;21:123-9.
    • (1987) Neuroscience , vol.21 , pp. 123-129
    • Pazos, A.1    Probst, A.2    Palacios, J.M.3
  • 28
    • 0024539757 scopus 로고
    • Effect of activation of central nervous system serotonin 1A receptors on cardiorespiratory function
    • Gillis RA, Hill KJ, Kirby JS, Quest JA, Hamosh P, Norman WP, et al. Effect of activation of central nervous system serotonin 1A receptors on cardiorespiratory function. J Pharmacol Exp Ther 1989;248:851-7.
    • (1989) J Pharmacol Exp Ther , vol.248 , pp. 851-857
    • Gillis, R.A.1    Hill, K.J.2    Kirby, J.S.3    Quest, J.A.4    Hamosh, P.5    Norman, W.P.6
  • 29
    • 0023525983 scopus 로고
    • Effects of serotonin, and serotonin 2 receptor agonists and antagonists on blood pressure, heart rate, and sympathetic nerve activity
    • McCall RE, Patel BN, Harris LT. Effects of serotonin, and serotonin 2 receptor agonists and antagonists on blood pressure, heart rate, and sympathetic nerve activity. J Pharmacol Exp Ther 1987;242:1152-9
    • (1987) J Pharmacol Exp Ther , vol.242 , pp. 1152-1159
    • McCall, R.E.1    Patel, B.N.2    Harris, L.T.3
  • 30
    • 0027192313 scopus 로고
    • Endothelium-dependent vasoregulation of coronary diameter and blood flow
    • Vogel RA. Endothelium-dependent vasoregulation of coronary diameter and blood flow. Circulation 1993;88:325-7.
    • (1993) Circulation , vol.88 , pp. 325-327
    • Vogel, R.A.1
  • 31
    • 0026589527 scopus 로고
    • Effects of monoamine uptake inhibitors on extracellular and platelet 5-hydroxytryptamine in rat blood: Different effects of clomipramine and fluoxetine
    • Ortiza J, Artigas F. Effects of monoamine uptake inhibitors on extracellular and platelet 5-hydroxytryptamine in rat blood: different effects of clomipramine and fluoxetine. Br J Pharmacol 1992;105:941-6.
    • (1992) Br J Pharmacol , vol.105 , pp. 941-946
    • Ortiza, J.1    Artigas, F.2
  • 32
    • 0028986770 scopus 로고
    • Pseudo-phaeochromocytoma after multiple drug interactions involving the selective monoamine oxidase inhibitor selegiline
    • Lefebrve H, Noblet C, Moore N, Wolf LM. Pseudo-phaeochromocytoma after multiple drug interactions involving the selective monoamine oxidase inhibitor selegiline. Clin Endocrinol 1995;42:95-8.
    • (1995) Clin Endocrinol , vol.42 , pp. 95-98
    • Lefebrve, H.1    Noblet, C.2    Moore, N.3    Wolf, L.M.4
  • 33
    • 0025613450 scopus 로고
    • Origin and metabolism of serotonin
    • Tyce GM Origin and metabolism of serotonin J Cardiovasc Pharmacol 1990;16(suppl 3):51-7.
    • (1990) J Cardiovasc Pharmacol , vol.16 , Issue.3 SUPPL. , pp. 51-57
    • Tyce, G.M.1
  • 34
    • 0027504033 scopus 로고
    • Plasma 5-hydroxyindoleacetic acid as an indicator of monoamine oxidase-A inhibition in rat brain and peripheral tissues
    • Celda P, Artigas F. Plasma 5-hydroxyindoleacetic acid as an indicator of monoamine oxidase-A inhibition in rat brain and peripheral tissues. J Neurochem 1993;59:2191-8.
    • (1993) J Neurochem , vol.59 , pp. 2191-2198
    • Celda, P.1    Artigas, F.2
  • 35
    • 0028117344 scopus 로고
    • Suicidality and 5-hydroxyindoleacetic acid concentration associated with a tryptophan hydroxylase polymorphism
    • Nielsen DA, Goldman D, Virkkunen M, Tokola R, Rawlings R, Linnoila M. Suicidality and 5-hydroxyindoleacetic acid concentration associated with a tryptophan hydroxylase polymorphism. Arch Gen Psychiatry 1994;51:34-8.
    • (1994) Arch Gen Psychiatry , vol.51 , pp. 34-38
    • Nielsen, D.A.1    Goldman, D.2    Virkkunen, M.3    Tokola, R.4    Rawlings, R.5    Linnoila, M.6
  • 36
    • 0026546195 scopus 로고
    • Repeated measures of platelet MAO activity and 5-HT in a group of suicidal women
    • Van Kempen GMJ, Notten P, Hengeveld MW. Repeated measures of platelet MAO activity and 5-HT in a group of suicidal women. Biol Psychiatry 1992;31:529-30.
    • (1992) Biol Psychiatry , vol.31 , pp. 529-530
    • Van Kempen, G.M.J.1    Notten, P.2    Hengeveld, M.W.3
  • 37
    • 0026091836 scopus 로고
    • Stress- And endotoxin-induced increases in brain tryptophan and serotonin metabolism depend upon sympathetic nervous system activity
    • Dunn AJ, Welch J. Stress- and endotoxin-induced increases in brain tryptophan and serotonin metabolism depend upon sympathetic nervous system activity. J Neurochem 1991;57:1615-22.
    • (1991) J Neurochem , vol.57 , pp. 1615-1622
    • Dunn, A.J.1    Welch, J.2
  • 38
    • 0025952271 scopus 로고
    • Pharmacological receptors on blood platelets
    • Hourani SMO, Cusack NJ. Pharmacological receptors on blood platelets. Pharmacol Rev 1991;43:243-98.
    • (1991) Pharmacol Rev , vol.43 , pp. 243-298
    • Hourani, S.M.O.1    Cusack, N.J.2
  • 39
    • 0023608310 scopus 로고
    • 5-Hydroxytryptamine involvement in the locomotor activity suppressant effects of amphetamine in the mouse
    • Bradbury AJ, Costall B, Naylor RJ, Onaivi ES. 5-Hydroxytryptamine involvement in the locomotor activity suppressant effects of amphetamine in the mouse Psychopharmacology 1987;93:457-65.
    • (1987) Psychopharmacology , vol.93 , pp. 457-465
    • Bradbury, A.J.1    Costall, B.2    Naylor, R.J.3    Onaivi, E.S.4
  • 40
    • 0027731280 scopus 로고
    • Am phetamine derivatives interact with both plasma membrane and secretory vesicle biogenic amine transporters
    • Schuldiner S, Steiner-Mordoch S, Yelin R, Wall SC, Rudnick G. Am phetamine derivatives interact with both plasma membrane and secretory vesicle biogenic amine transporters Mol Pharmacol 1993;44:1227-31.
    • (1993) Mol Pharmacol , vol.44 , pp. 1227-1231
    • Schuldiner, S.1    Steiner-Mordoch, S.2    Yelin, R.3    Wall, S.C.4    Rudnick, G.5
  • 41
    • 9244245844 scopus 로고
    • Fluvoxamine preferentially increases extracellular 5-hydroxytryptamine in the rat raphe nuclei: An in vivo microdialysis study
    • Bel N, Artigas F. Fluvoxamine preferentially increases extracellular 5-hydroxytryptamine in the rat raphe nuclei: an in vivo microdialysis study. Eur J Pharmacol 1992;25:243-50.
    • (1992) Eur J Pharmacol , vol.25 , pp. 243-250
    • Bel, N.1    Artigas, F.2
  • 42
    • 0027403975 scopus 로고
    • The presence of a serotonin uptake inhibitor alters pharmacological manipulations of serotonin release
    • Kreiss DS, Wieland S, Lucki I. The presence of a serotonin uptake inhibitor alters pharmacological manipulations of serotonin release. Neuroscience 1993;52:295-301.
    • (1993) Neuroscience , vol.52 , pp. 295-301
    • Kreiss, D.S.1    Wieland, S.2    Lucki, I.3
  • 43
    • 0025922761 scopus 로고
    • 14C] 5-hydroxytryptamine from human platelets by red wine
    • 14C] 5-hydroxytryptamine from human platelets by red wine. Life Sci 1991;48:2297-300.
    • (1991) Life Sci , vol.48 , pp. 2297-2300
    • Jarman, J.1    Glover, V.2    Sandler, M.3
  • 44
    • 84920248128 scopus 로고
    • Phenolic substances in red wine and release of platelet 5-hydroxytryptamine
    • Pattichis K, Louca LL, Jarman J, Sandler M, Glover V. Phenolic substances in red wine and release of platelet 5-hydroxytryptamine (letter). Lancet 1993;341:1104.
    • (1993) Lancet , vol.341 , pp. 1104
    • Pattichis, K.1    Louca, L.L.2    Jarman, J.3    Sandler, M.4    Glover, V.5
  • 45
    • 85035165893 scopus 로고    scopus 로고
    • Ruoxetine and phentermine interaction may produce the serotonin syndrome
    • in press
    • Bostwick JM, Brown TM. Ruoxetine and phentermine interaction may produce the serotonin syndrome. J Clin Psychopharmacol (in press).
    • J Clin Psychopharmacol
    • Bostwick, J.M.1    Brown, T.M.2
  • 46
    • 0028113632 scopus 로고
    • The pharmacology of antidepressants at the synapse: Focus on newer compounds
    • Richelson E. The pharmacology of antidepressants at the synapse: focus on newer compounds. J Clin Psychiatry 1994;55(suppl A):34-9.
    • (1994) J Clin Psychiatry , vol.55 , Issue.SUPPL. A , pp. 34-39
    • Richelson, E.1
  • 47
    • 70449145120 scopus 로고
    • Two types, of tryplamine receptor
    • Gaddum JH, Picarelli ZP. Two types, of tryplamine receptor (letter). Br J Pharmacol 1957;12:323.
    • (1957) Br J Pharmacol , vol.12 , pp. 323
    • Gaddum, J.H.1    Picarelli, Z.P.2
  • 51
    • 0026639447 scopus 로고
    • Biochemical, physiologic al, and pathological aspects of the peripheral benzodiazepine receptor
    • Gavish M, Katz Y, Bar-Ami S, Weizman R. Biochemical, physiologic al, and pathological aspects of the peripheral benzodiazepine receptor. J Neurochem 1992;58:1589-1601.
    • (1992) J Neurochem , vol.58 , pp. 1589-1601
    • Gavish, M.1    Katz, Y.2    Bar-Ami, S.3    Weizman, R.4
  • 52
    • 0025836925 scopus 로고
    • Serotonin reuptake inhibitors, paranoia, and the ventral basal ganglia
    • Lauterbach EC. Serotonin reuptake inhibitors, paranoia, and the ventral basal ganglia. Clin Neuropharmacol 1991;14:547-55.
    • (1991) Clin Neuropharmacol , vol.14 , pp. 547-555
    • Lauterbach, E.C.1
  • 53
  • 54
    • 0027495863 scopus 로고
    • Molecular, cellular and behavioral aspects of peripheral-type benzodiazepine receptors
    • Weizman R, Gavish M. Molecular, cellular and behavioral aspects of peripheral-type benzodiazepine receptors. Clin Neuropharmacol 1993;16:401-17.
    • (1993) Clin Neuropharmacol , vol.16 , pp. 401-417
    • Weizman, R.1    Gavish, M.2
  • 56
    • 0028603653 scopus 로고
    • Pharmacogenetics and drug metabolism of newer antidepressant agents
    • DeVanme CL. Pharmacogenetics and drug metabolism of newer antidepressant agents. J Clin Psychiatry 1994;55(suppl 12):38-45.
    • (1994) J Clin Psychiatry , vol.55 , Issue.12 SUPPL. , pp. 38-45
    • DeVanme, C.L.1
  • 59
    • 0027167470 scopus 로고
    • Inhibition by paroxetine of desipramine metabolism in extensive but not poor metabolizers of sparteine
    • Brosen K, Hansen JG, Nielsen KK, Sindrup SH, Gram LF. Inhibition by paroxetine of desipramine metabolism in extensive but not poor metabolizers of sparteine. Eur J Clin Pharmacol 1993;44:349-55.
    • (1993) Eur J Clin Pharmacol , vol.44 , pp. 349-355
    • Brosen, K.1    Hansen, J.G.2    Nielsen, K.K.3    Sindrup, S.H.4    Gram, L.F.5
  • 60
    • 0026787192 scopus 로고
    • The effect of selective serotonin reuptake inhibitors on cytochrome P4502D6 (CYP2D6) activity in human liver microsomes
    • Crewe HK, Lennard MS, Tucker GT, Woods FR, Haddock RE. The effect of selective serotonin reuptake inhibitors on cytochrome P4502D6 (CYP2D6) activity in human liver microsomes. Br J Clin Pharmacol 1992;34:262-5.
    • (1992) Br J Clin Pharmacol , vol.34 , pp. 262-265
    • Crewe, H.K.1    Lennard, M.S.2    Tucker, G.T.3    Woods, F.R.4    Haddock, R.E.5
  • 61
    • 0022569244 scopus 로고
    • The serotonin syndrome: Case responsive to propranolol
    • Guze BH, Baxter LR. The serotonin syndrome: case responsive to propranolol. J Clin Psychopharmacol 1986;6:119-20.
    • (1986) J Clin Psychopharmacol , vol.6 , pp. 119-120
    • Guze, B.H.1    Baxter, L.R.2


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