Proteomic analysis of the differential protein expression reveals nuclear GAPDH in activated T lymphocytes

PLoS ONE

Volumn 4, Issue 7, 2009, Pages

  Sheng, Wei Yun ^a,b   Wang, Tzu Chien V ^a  

^a CHANG GUNG UNIVERSITY   (Taiwan)

^b University of North Carolina   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA ACTININ 1; BETA5 TUBULIN; CARBONATE DEHYDRATASE II; CATHEPSIN B PRECURSOR; CATHEPSIN D; COFILIN; CYTOSKELETON PROTEIN; FIBRINOGEN GAMMA CHAIN; FRUCTOSE BISPHOSPHATE ALDOLASE A; FUMARATE HYDRATASE; FUMARATE HYDRATASE PRECURSOR; GAMMA ACTIN; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; HEAT SHOCK COGNATE PROTEIN 54; MACROPHAGE CAPPING PROTEIN; MANGANESE SUPEROXIDE DISMUTASE; PHOSPHOGLYCERATE KINASE 1; PYRUVATE KINASE 3; SORCIN; TALIN; TRANSGELIN 2; TRIOSEPHOSPHATE ISOMERASE; UBIQUITOUS TROPOMODULIN; UNCLASSIFIED DRUG; VINCULIN; PRIMER DNA;

ARTICLE; CELL ACTIVATION; CELL DIFFERENTIATION; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DOWN REGULATION; GEL ELECTROPHORESIS; HUMAN; HUMAN CELL; MOLECULAR WEIGHT; PROMOTER REGION; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEOMICS; T LYMPHOCYTE; TRANSCRIPTION REGULATION; UPREGULATION; WESTERN BLOTTING; CELL NUCLEUS; CONFOCAL MICROSCOPY; ENZYMOLOGY; GENETIC TRANSCRIPTION; LYMPHOCYTE ACTIVATION; METABOLISM; NUCLEOTIDE SEQUENCE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TWO DIMENSIONAL GEL ELECTROPHORESIS;

BASE SEQUENCE; BLOTTING, WESTERN; CELL NUCLEUS; CHROMATIN IMMUNOPRECIPITATION; DNA PRIMERS; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASES; LYMPHOCYTE ACTIVATION; MICROSCOPY, CONFOCAL; PROTEOMICS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; T-LYMPHOCYTES; TRANSCRIPTION, GENETIC;

EID: 67651249577     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0006322     Document Type: Article

References (26)

1. Germain RN (2003) Ligand-dependent regulation of T cell development and activation. Immunol Res 27: 277-286.
2. Rincon M (2001) MAP-kinase signaling pathways in T cells. Curr Opin Immunol 13: 339-345.
3. Arendt CW, Albrecht B, Soos TJ, Littman DR (2002) Protein kinase C-theta: signaling from the center of the T-cell synapse. Curr Opin Immunol 14: 323-330.
4. Caron M, Imam-Sghiouar N, Poirier F, Le Caer JP, Labas V, et al. (2002) Proteomic map and database of lymphoblastoid proteins. J Chromatogr B Analyt Technol Biomed Life Sci 771: 197-209.
5. Rautajoki K, Nyman TA, Lahesmaa R (2004) Proteome characterization of human T helper 1 and 2 cells. Proteomics 4: 84-92.
6. Nyman TA, Rosengren A, Syyrakki S, Pellinen TP, Rautajoki K, et al. (2001) A proteome database of human primary T helper cells. Electrophoresis 22: 4375-4382.
7. Sheng WY, Chien YL, Wang TC (2003) The dual role of protein kinase C in the regulation of telomerase activity in human lymphocytes. FEBS Lett 540: 91-95.
8. Blum H, Beier H, Gross HJ (1987) Improved silver staining of plant proteins, RNA and DNA in polyacrylamide. Electrophoresis 8: 93-99.
9. Sheng WY, Chen YR, Wang TC (2006) A major role of PKC theta and NFkappaB in the regulation of hTERT in human T lymphocytes. FEBS Lett 580: 6819-6824.
10. Sirover MA (1999) New insights into an old protein: the functional diversity of mammalian glyceraldehyde-3-phosphate dehydrogenase. Biochim Biophys Acta 1432: 159-184.
11. Sirover MA (2005) New nuclear functions of the glycolytic protein, glyceraldehyde-3-phosphate dehydrogenase, in mammalian cells. J Cell Biochem 95: 45-52.
12. Kim JW, Kim TE, Kim YK, Kim YW, Kim SJ, et al. (1999) Antisense oligodeoxynucleotide of glyceraldehyde-3-phosphate dehydrogenase gene inhibits cell proliferation and induces apoptosis in human cervical carcinoma cell lines. Antisense Nucleic Acid Drug Dev 9: 507-513.
13. Epner DE, Sawa A, Isaacs JT (1999) Glyceraldehyde-3-phosphate dehydrogenase expression during apoptosis and proliferation of rat ventral prostate. Biol Reprod 61: 687-691.
14. Sundararaj KP, Wood RE, Ponnusamy S, Salas AM, Szulc Z, et al. (2004) Rapid shortening of telomere length in response to ceramide involves the inhibition of telomere binding activity of nuclear glyceraldehyde-3-phosphate dehydrogenase. J Biol Chem 279: 6152-6162.
15. Zheng L, Roeder RG, Luo Y (2003) S phase activation of the histone H2B promoter by OCA-S, a coactivator complex that contains GAPDH as a key component. Cell 114: 255-266.
16. Ellisen LW, Palmer RE, Maki RG, Truong VB, Tamayo P, et al. (2001) Cascades of transcriptional induction during human lymphocyte activation. Eur J Cell Biol 80: 321-328.
17. Baier G (2003) The PKC gene module: molecular biosystematics to resolve its T cell functions. Immunol Rev 192: 64-79.
18. Calderwood DA, Shattil SJ, Ginsberg MH (2000) Integrins and actin filaments: reciprocal regulation of cell adhesion and signaling. J Biol Chem 275: 22607-22610.
19. Liu S, Calderwood DA, Ginsberg MH (2000) Integrin cytoplasmic domain-binding proteins. J Cell Sci 113: 3563-3571.
20. Anderson L, Seilhamer J (1997) A comparison of selected mRNA and protein abundances in human liver. Electrophoresis 18: 533-537.
21. Gygi SP, Rochon Y, Franza BR, Aebersold R (1999) Correlation between protein and mRNA abundance in yeast. Mol Cell Biol 19: 1720-1730.
22. Cha H, Hancock C, Dangi S, Maiguel D, Carrier F, et al. (2004) Phosphorylation regulates nucleophosmin targeting to the centrosome during mitosis as detected by cross-reactive phosphorylation-specific MKK1/MKK2 antibodies. Biochem J 378: 857-865.
23. Bosser R, Faura M, Serratosa J, Renau-Piqueras J, Pruschy M, et al. (1995) Phosphorylation of rat liver heterogeneous nuclear ribonucleoproteins A2 and C can be modulated by calmodulin. Mol Cell Biol 15: 661-670.
24. Ryzlak MT, Pietruszko R (1988) Heterogeneity of glyceraldehyde-3-phosphate dehydrogenase from human brain. Biochim Biophys Acta 954: 309-324.
25. Tisdale EJ, Kelly C, Artalejo CR (2004) Glyceraldehyde-3-phosphate dehydrogenase interacts with Rab2 and plays an essential role in endoplasmic reticulum to Golgi transport exclusive of its glycolytic activity. J Biol Chem 279: 54046-54052.
26. Sirover MA (1997) Role of the glycolytic protein, glyceraldehyde-3-phosphate dehydrogenase, in normal cell function and in cell pathology. J Cell Biochem 66: 133-140.