Is hypercholesterolemia a friend or a foe of tuberculosis?

Infection and Immunity

Volumn 77, Issue 8, 2009, Pages 3514-

  Han, Runlin ^a  

^a INNER MONGOLIA AGRICULTURAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN E; LOW DENSITY LIPOPROTEIN RECEPTOR;

DIABETES MELLITUS; DISEASE SEVERITY; HYPERCHOLESTEROLEMIA; KLEBSIELLA PNEUMONIAE INFECTION; LETTER; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; OBESITY; PRIORITY JOURNAL; RISK FACTOR; SALMONELLA ENTERICA; T LYMPHOCYTE ACTIVATION; TUBERCULOSIS;

ANIMALS; APOLIPOPROTEINS E; HYPERCHOLESTEROLEMIA; MICE; TUBERCULOSIS;

EID: 67651225305     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.00469-09     Document Type: Letter

References (11)

1. de Bont, N., M. G. Netea, P. N. Demacker, I. Verschueren, B. J. Kullberg, K. W. van Dijk, J. W. van der Meer, and A. F. Stalenhoef. 1999. Apolipoprotein E knock-out mice are highly susceptible to endotoxemia and Klebsiella pneumoniae infection. J. Lipid Res. 40:680-685.
2. Deniz, O., S. Gumus, H. Yaman, F. Ciftci, F. Ors, E. Cakir, E. Tozkoparan, H. Bilgic, and K. Ekiz. 2007. Serum total cholesterol, HDL-C and LDL-C concentrations significantly correlate with the radiological extent of disease and the degree of smear positivity in patients with pulmonary tuberculosis. Clin. Biochem. 40:162-166.
3. Grunfeld, C., and K. R. Feingold. 2008. HDL and innate immunity: a tale of two apolipoproteins. J. Lipid Res. 49:1605-1606.
4. Martens, G. W., M. C. Arikan, J. Lee, F. Ren, D. Greiner, and H. Kornfeld. 2007. Tuberculosis susceptibility of diabetic mice. Am. J. Respir. Cell Mol. Biol. 37:518-524.
5. Martens, G. W., M. C. Arikan, J. Lee, F. Ren, T. Vallerskog, and H. Kornfeld. 2008. Hypercholesterolemia impairs immunity to tuberculosis. Infect. Immun. 76:3464-3472.
6. Netea, M. G., P. N. Demacker, B. J. Kullberg, O. C. Boerman, I. Verschueren, A. F. Stalenhoef, and J. W. van der Meer. 1996. Low-density lipoprotein receptor-deficient mice are protected against lethal endotoxemia and severe gram-negative infections. J. Clin. Investig. 97:1366-1372.
7. Netea, M. G., L. A. Joosten, M. Keuter, F. Wagener, A. F. Stalenhoef, J. W. van der Meer, and B. J. Kullberg. 2009. Circulating lipoproteins are a crucial component of host defense against invasive Salmonella typhimurium infection. PLoS ONE 4:e4237.
8. Perez-Guzman, C., M. H. Vargas, F. Quinonez, N. Bazavilvazo, A. Aguilar, and the Instituto Nacional de Enfermedades Respiratorias Tuberculosis Outpatient Service Team. 2005. A cholesterol-rich diet accelerates bacteriologic sterilization in pulmonary tuberculosis. Chest 127:643-651.
9. Ravnskov, U. 2003. High cholesterol may protect against infections and atherosclerosis. QJM 96:927-934.
10. Schreyer, S. A., C. Vick, T. C. Lystig, P. Mystkowski, and R. C. LeBoeuf. 2002. LDL receptor but not apolipoprotein E deficiency increases dietinduced obesity and diabetes in mice. Am. J. Physiol. Endocrinol. Metab. 282:E207-E214.
11. Wilson, R. F., J. F. Barletta, and J. G. Tyburski. 2003. Hypocholesterolemia in sepsis and critically ill or injured patients. Crit. Care 7:413-414.