Tissue distribution and excretion of bromotetrandrine in rats

Yaoxue Xuebao

Volumn 40, Issue 5, 2005, Pages 453-456

  Xiao, Shu Hua ^a   Wei, Guang Li ^a   Lu, Rong ^a   Liu, Chang Xiao ^a   Wang, Feng Peng ^b  

^a TIANJIN INSTITUTE OF PHARMACEUTICAL RESEARCH   (China)

^b SICHUAN UNIVERSITY   (China)

Author keywords

Bromotetrandrine; Excretion; HPLC; Tissue distribution

Indexed keywords

ANTINEOPLASTIC AGENT; BENZYLISOQUINOLINE DERIVATIVE; BROMOTETRANDRINE;

ANIMAL; ARTICLE; BILE; CHEMICAL STRUCTURE; CHEMISTRY; FECES; FEMALE; HEART MUSCLE; KIDNEY; LIVER; LUNG; MALE; METABOLISM; RAT; TISSUE DISTRIBUTION; URINE; WISTAR RAT;

ANIMALS; ANTINEOPLASTIC AGENTS; BENZYLISOQUINOLINES; BILE; FECES; FEMALE; KIDNEY; LIVER; LUNG; MALE; MOLECULAR STRUCTURE; MYOCARDIUM; RATS; RATS, WISTAR; TISSUE DISTRIBUTION;

EID: 22244475402     PISSN: 05134870     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (6)

1. Jiang JW, Xiao QX. Handbook of Active Principles of Medicinal Plants [M]. Beinjing; People's Health Press, 1986. 631.
2. Xiao SH, Wei GL, Lu R, et al. Pharmacokinetics of bromotetrandrine (W198) in rats and Beagle dogs. Acta Pharm Sin, 2004,39(4):301-304.
3. Xiao SH, Wei GL, Lu R, et al. Studies on pharmacokinetics of bromotetrandrine in animals (II) Effect of coadministration of bromotetrandrine with adriamycin on the pharmacokinetics. Asian J Drug Metab Pharmacokinet, 2004,4(1):63-66.
4. Sun H, Han GZ, Su CY, et al. Pharmacokinetics and distribution of isotetrandrine in rats. Acta Pharm Sin, 1990,25(4):241-246.
5. Lin MB, Zhang W, Zhao XW, et al. Biotransformation of tetrandrine in rats and in men. Acta Pharm Sin, 1982,17(10):728-734.
6. Liu CX, Wei GL, Li QS. Methodology study of validation for bioanalysis on studies on pharmacokinetics, bioavailability. Asian J Drug Metab Pharmacokinet, 2001,1(4):279-286.