Physiological carotid body denervation during aging

Advances in Experimental Medicine and Biology

Volumn 648, Issue , 2009, Pages 257-263

  Di Giulio, C ^a   Antosiewicz, J ^a   Walski, M ^a   Petruccelli, G ^a   Verratti, V ^a   Bianchi, G ^a   Pokorski, M ^a  

^a UNIVERSITY OF CHIETI   (Italy)

Author keywords

Aging; Carotid body; Denervation; Dense core vesicles; HIF 1 ; Mitochondria; NOS 1; Synaptic junctions; VEGF

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1ALPHA; LIPOFUSCIN; NEURONAL NITRIC OXIDE SYNTHASE; REACTIVE OXYGEN METABOLITE; VASCULOTROPIN; OXYGEN; PROTEIN;

AGING; ANIMAL CELL; ANIMAL TISSUE; CAROTID BODY; CELL VOLUME; CELLULAR PARAMETERS; CHEMORECEPTOR; CHEMOSENSITIVITY; CONFERENCE PAPER; CONTROLLED STUDY; DENSE BODY; EXTRACELLULAR MATRIX; IMMUNOHISTOCHEMISTRY; MALE; MITOCHONDRIAL NUMBER; MITOCHONDRIAL VOLUME; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SENESCENCE; SYNAPSE; ANIMAL; ARTICLE; ELECTRON MICROSCOPY; GENE EXPRESSION REGULATION; HOMEOSTASIS; METABOLISM; PHYSIOLOGICAL STRESS; PHYSIOLOGY; ULTRASTRUCTURE; WISTAR RAT;

RATTUS NORVEGICUS;

AGING; ANIMALS; CAROTID BODY; GENE EXPRESSION REGULATION; HOMEOSTASIS; MALE; MICROSCOPY, ELECTRON; OXYGEN; PROTEINS; RATS; RATS, WISTAR; STRESS, PHYSIOLOGICAL; SYNAPSES;

EID: 67651202578     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-90-481-2259-2_29     Document Type: Conference Paper

References (13)

1. Amicarelli, F., Ragnelli, A. M., Aimola, P., Bonfigli, A., Colafarina, S., Di Ilio, C., Miranda, M. 1999, Age-dependent ultrastructural alterations and biochemical response of rat skeletal muscle after hypoxic or hyperoxic treatments, Biochim Biophys Acta, 1453:105-14. (Pubitemid 29065462)
2. Bunn, A. F., Poyton, R. O., 1996. Oxygen sensing and molecular adaptation to hypoxia, Physiol Rev, 76:839-85. (Pubitemid 26286080)
3. Cerveri, I., Zoia, M. C., Fanfulla, F., Spagnolatti, L., Berrayah, L., Grassi, M., Tinelli, C. 1995, Reference values of arterial oxygen tension in the middle-aged and elderly, Am J Respir Crit Care Med, 152(3):934-41.
4. Conde, S., Obeso, A., Rigual, R., Monteiro, E. C., Gonzales, C. 2006, Function of the rat carotid body chemoreceptors in ageing, J Neurochemistry, 99:711-23. (Pubitemid 44583431)
5. Dejours, P., Dejours, S. 1992, The effects of barometric pressure according to Paul Bert: The question today, Int J Sports Med, 13:1-5.
6. Di Giulio, C., Bianchi, G., Cacchio, M., Macrì, M. A., Ferrero, G., Rapino, C., Verratti, V., Piccirilli, M., Artese, L. 2003, Carotid body HIF-1alpha, VEGF and NOS expression during aging and hypoxia, Adv Exp Med Biol, 536:603-10.
7. Dymecka, A., Walski, M., Pokorski, M. 2006, Ultrastructural degradation of the carotid body in the aged rat: Is there a role for atherosclerosis in the main carotid arteries?, J Physiol Pharmacol, 57 Supp 4:85-90. (Pubitemid 44638188)
8. Guenard, H. 1998, Respiration and aging, Rev Mal Respir, 15:713-21. Review.
9. Gunnarsson, L., Tokics, L., Brismar, B., Hedenstierna, G. 1996, Influence of age on circulation and arterial blood gases in man, Acta Anaesthesiol Scand, 40(2):237-43. (Pubitemid 26061963)
10. Lahiri, S., Mulligan, E., Andronikou, S., Shirahata, M., Mokashi, A. 1987, Carotid body chemosensory function in prolonged normobaric hyperoxia in the cat, J Appl Physiol, 62(5):1924-31. (Pubitemid 17108140)
11. Martinelli, M., Winterhalder, R., Cerretelli, P., Howald, H., Hoppeler, H. 1990, Muscle lipofuscin content and satellite cell volume is increased after high altitude exposure in humans, Experientia, 46:672-76. (Pubitemid 20216628)
12. Pokorski, M., Walski, M., Dymecka, A., Marczak, M. 2004, The aging carotid body, J Physiol Pharmacol, 55:107-13.
13. Ratcliffe, P. F., Eckardt, K.-U., Bauer, C., 1996. Hypoxia erythropoietin gene expression, and erythropoiesis. In: Handbook of Physiology, ed. M. J. Fregly and C. M. Blatteis, C. M., Section 4: Environmental Physiology, vol. II. American Physiological Society, Oxford University Press, New York, pp. 1125-53.