The role of ZIP8 down-regulation in cadmium-resistant metallothionein-null cells

Journal of Applied Toxicology

Volumn 29, Issue 5, 2009, Pages 367-373

  Fujishiro, Hitomi ^a   Okugaki, Satomi ^a   Kubota, Keisuke ^a   Fujiyama, Tastuo ^a   Miyataka, Hideki ^a   Himeno, Seiichiro ^a  

^a TOKUSHIMA BUNRI UNIVERSITY   (Japan)

Author keywords

Cadmium; DMT1; Iron; Metallothionein; Resistance; Transport; Zinc; ZIP8

Indexed keywords

CADMIUM; MESSENGER RNA; METALLOTHIONEIN; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG; ZINC TRANSPORTER; ZIP8;

ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; DNA MICROARRAY; DOWN REGULATION; GENE EXPRESSION; IMMUNOBLOTTING; MOUSE; NONHUMAN; NULL CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN TRANSPORT; REAL TIME POLYMERASE CHAIN REACTION;

ANIMALS; ANTIBODIES, MONOCLONAL; CADMIUM; CATION TRANSPORT PROTEINS; CELL LINE; DOWN-REGULATION; DRUG RESISTANCE; MALE; METALLOTHIONEIN; MICE; MICE, INBRED ICR; ORGAN SPECIFICITY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

MAMMALIA;

EID: 67651177635     PISSN: 0260437X     EISSN: 10991263     Source Type: Journal    
DOI: 10.1002/jat.1419     Document Type: Article

References (29)

1. Bannon DI, Abounader R, Lees PS, Bressler JP. 2003. Effect of DMT1 knockdown on iron, cadmium, and lead uptake in Caco-2 cells. Am. J. Physiol. Cell Physiol. 284: C44-50.
2. Chomczynski P, Sacchi N. 1987. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction, Anal. Biochem. 162: 156-159. (Pubitemid 17064313)
3. Cousins RJ, Liuzzi JP, Lichten LA. 2006. Mammalian zinc transport, trafficking, and signals. J. Biol. Chem. 281: 24085-24089.
4. Dalton TP, He L, Wang B, Miller ML, Jin L, Stringer KF, Chang X, Baxter CS, Nebert DW. 2005. Identification of mouse SLC39A8 as the transporter responsible for cadmium-induced toxicity in the testis. Proc. Natl Acad. Sci. USA 102: 3401-3406. (Pubitemid 40328057)
5. Eide DJ. 2004. The SLC39 family of metal ion transporters. Pflugers Arch. 447: 796-800.
6. Flanagan PR, McLellan JS, Haist J, Cherian G, Chamberlian MJ, Valberg LS. 1978. Increased dietary cadmium absorption in mice and human subjects with iron deficiency. Gastroenterology 74: 841-846. (Pubitemid 8332337)
7. Fujishiro H, Okugaki S, Nagao S, Satoh M, Himeno S. 2006. Characterization of gene expression profiles of metallothionein-null cadmium-resistant cells. J. Health Sci. 52: 292-299. Available from: http://www.jstage.jst.go.jp/article/jhs/52/3/52292/-article. DOI: 10.1248/jhs.52.292. (Pubitemid 43824822)
8. Galeotti T, Palombini G, Rossum GD. 1995. Manganese content and high affinity transport in liver and hepatoma. Arch. Biochem. Biophys. 322: 453-459.
9. Girijashanker K, He L, Soleimani M, Reed JM, Li H, Liu Z, Wang B, Dalton TP, Nebert DW. 2008. Slc39a14 gene encodes Zrt- and Irt-related Protein (ZIP) 14, a metal/bicarbonate symporter: similarities to the ZIP8 transporter. Mol. Pharmacol. 73: 1-11. (Pubitemid 351574831)
10. Grady DL, Moyzis RK, Hildebrand CE. 1987. Molecular and cellular mechanisms of cadmium resistance in cultured cells. Experientia (Suppl.) 52: 447-456.
11. Gunshin H, Mackenzie B, Berger UV, Gunshin Y, Romero MF, Boron WF, Nussberger S, Gollan JL, Hediger MA. 1997. Cloning and characterization of a mammalian proton-coupled metal-ion transporter. Nature 388: 482-488. (Pubitemid 27328927)
12. He L, Girijashanker K, Dalton TP, Reed J, Li H, Soleimani M, Nebert DW. 2006. ZIP8, member of the solute-carrier-39 (SLC39) metal-transporter family: characterization of transporter properties. Mol. Pharmacol. 70: 171-180. (Pubitemid 43920807)
13. Himeno S. 2002. Application of metallothionein null cells to investigation of cadmium transport. J. Inorg. Biochem. 88: 207-212. (Pubitemid 34136082)
14. Himeno S, Yanagiya T, Enomoto S, Kondo Y, Imura N. 2002. Cellular cadmium uptake by the transport system for manganese. Tohoku J. Exp. Med. 196: 43-50. (Pubitemid 34464408)
15. Kim DW, Kim KY, Choi BS, Youn P, Ryu DY, Klaassen CD, Park JD. 2007. Regulation of metal transporters by dietary iron, and the relationship between body iron levels and cadmium uptake. Arch. Toxicol. 81: 327-334. (Pubitemid 46701591)
16. Klugbauer N, Marais E, Lacinova L, Hofmann F. 1999. A T-type calcium channel from mouse brain. Pflügers Arch. 437: 710-715. (Pubitemid 29161927)
17. Kondo Y, Yanagiya T, Himeno S, Yamabe Y, Schwartz D, Akimoto M, Lazo JS, Imura N. 1999. Simian virus 40-transformed metallothionein null cells showed increased sensitivity to cadmium but not to zinc, copper, mercury or nickel. Life Sci. 64: 145-150. (Pubitemid 29130578)
18. 1G in cadmium uptake. Mol. Pharmacol. 69: 629-639.
19. Li W, Kagan HM, Chou IN. 1994. Alterations in cytoskeletal organization and homeostasis of cellular thiols in cadmium-resistant cells. Toxicol. Appl. Pharmacol. 126: 114-123. (Pubitemid 24168875)
20. 3--dependent symporter: Kinetics, electrogenicity and trafficking. Biochem. Biophys. Res. Commun. 365: 814-820.
21. Martine L, Martineau C, Jumarie C, Moreau R. 2008. Characterization of cadmium uptake and cytotoxicity in human osteoblast-like MG-63 cells. Toxicol. Appl. Pharmacol. 231: 308-317.
22. Min K-S, Ueda H, Tanaka K. 2008. Involvement of intestinal calcium transporter 1 and metallothionein in cadmium accumulation in the liver and kidney of mice fed a low-calcium diet. Toxicol. Lett. 176: 85-92. (Pubitemid 350251069)
23. Perez-Reyes E, Cribbs LL, Daud A, Lacerda AE, Barclay J, Williamson MP, Fox M, Rees M, Lee JH. 1998. Molecular characterization of a neuronal low voltage-activated T-type calcium channel. Nature 391: 896-900. (Pubitemid 28157667)
24. Ryu DY, Lee SJ, Park SW, Choi BS, Klaassen CD, Park JD. 2004. Dietary iron regulates intestinal cadmium absorption through iron transporters in rats. Toxicol. Lett. 152: 19-25.
25. Suzuki KT, Imura N, Kimura M. 1993. Metallothionein III. Biological Roles and Medical Implications. Birhauser: Basel.
26. Suzuki T, Momoi K, Hosoyamada M, Kimura M, Shibasaki T. 2008. Normal cadmium uptake in microcytic anemia mk/mk mice suggests that DMT1 is not the only cadmium transport in vivo. Toxicol. Appl. Pharmacol. 227: 462-467.
27. Wang B, Schneider SN, Dragin N, Girijashanker K, Dalton TP, He L, Miller ML, Stringer KF, Soleimani M, Richardson DD, Nebert DW. 2007. Enhanced cadmium-induced testicular necrosis and renal proximal tubule damage caused by gene-dose increase in a SLC39a8-transgenic mouse line. Am. J. Physiol. Cell Physiol. 292: C1523-1535. (Pubitemid 46631719)
28. Yanagiya T, Imura N, Kondo Y, Himeno S. 1999. Reduced uptake and enhanced release of cadmium in cadmium-resistant metallothionein null fibroblasts. Life Sci. 65: 177-182. (Pubitemid 29421937)
29. Yanagiya T, Imura N, Kondo Y, Himeno S. 2000. Suppression of a high-affinity transport system for manganese in cadmium-resistant metallothionein null cells. J. Pharmacol. Exp. Ther. 292: 1080-1086. (Pubitemid 30136604)