Cell-specific effects of nitric oxide deficiency on parathyroid hormone-related peptide (PTHrP) responsiveness and PTH1 receptor expression in cardiovascular cells

Endocrinology

Volumn 150, Issue 8, 2009, Pages 3735-3741

  Schreckenberg, Rolf ^a   Wenzel, Sibylle ^a   Rebelo, Rui Manuel Da Costa ^a   Röthig, Anja ^a   Meyer, Rainer ^b   Schlüter, Klaus Dieter ^a  

^a JUSTUS LIEBIG UNIVERSITY   (Germany)

^b UNIVERSITY HOSPITAL BONN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; PARATHYROID HORMONE RECEPTOR 1; PARATHYROID HORMONE RELATED PROTEIN; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL SPECIFICITY; CHRONOTROPISM; CONTROLLED STUDY; CORONARY BLOOD VESSEL; DOWN REGULATION; ENDOTHELIUM CELL; FEMALE; HEART RATE; ISOLATED HEART; MUSCLE FIBER CONTRACTION; NONHUMAN; OVARIECTOMY; PERFUSION PRESSURE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; VITAL SIGN;

ANIMALS; BLOOD PRESSURE; BLOTTING, WESTERN; CELLS, CULTURED; ENZYME INHIBITORS; FEMALE; GENE EXPRESSION REGULATION; HEART RATE; HEART VENTRICLES; MYOCYTES, CARDIAC; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; OVARIECTOMY; PARATHYROID HORMONE-RELATED PROTEIN; PROTEIN-SERINE-THREONINE KINASES; RATS; RATS, WISTAR; RECEPTOR, PARATHYROID HORMONE, TYPE 1; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 67651176097     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2008-1585     Document Type: Article

References (33)

1. Burtis WJ, Wu T, Bunch C, Wysolmerski JJ, Insogna KL, Weir EC, Broadus AE, Stewart AF 1987 Identification of a novel 17,000-dalton parathyroid hormone-like adenylate cyclase stimulating protein from a tumor associated with humoral hypercalcemia of malignancy. J Biol Chem 262:7151-7156
2. Schlüter K, Katzer C, Frischkopf K, Wenzel S, Taimor G, Piper HM 2000 Expression, release, and biological activity of parathyroid hormone-related peptide from coronary endothelial cells. Circ Res 86:946-951
3. Bui TD, Shallal A, Malik AN, al-Mahdawi S, Moscoso G, Bailey ME, Burton PB, Moniz C 1993 Parathyroid hormone related peptide gene expression in human fetal and adult heart. Cardiovasc Res 27:1204-1208
4. Deftos LJ, Burton DW, Brandt DW 1993 Parathyroid hormone-like protein (PLP) is a secretory product of arterial myocytes. J Clin Invest 92:727-735
5. Kalinowski L, Dobrucki LW, Malinski T 2001 Nitric oxide as a second messenger in parathyroid hormone-related protein signaling. J Endocrinol 170:433-440
6. Sutliff RL, Weber CS, Qian J, Miller ML, Clemens TL, Paul RJ 1999 Vasorelaxant properties of parathyroid hormone-related protein in the mouse: evidence for endothelium involvement independent of nitric oxide formation. Endocrinology 140:2077-2083
7. Jansen J, Gres P, Umschlag C, Heinzel FR, Degenhardt H, Schluter K-D, Heusch G, Schulz R 2003 Parathyroid hormone-related peptide improves contractile function of stunned myocardium in rats and pigs. Am J Physiol 284:H49-H55
8. Grohé C, van Eickels M, Wenzel S, Meyer R, Degenhardt H, Doevendans PA, Heinemann MP, Ross G, Schlüter KD 2004 Sex-specific differences in ventricular expression and function of parathyroid hormone-related peptide. Cardiovasc Res 61:307-316
9. Schlüter KD, Weber M, Piper HM 1997 Effects of PTHrP(107-111) and PTHrP(7-34) on adult cardiomyocytes. J Mol Cell Cardiol 29:3057-3065
10. Gordon T, Kannel WB, Hjortland MC, McNamara PM 1978 Menopause and coronary heart disease: the Framingham study. Ann Intern Med 89:157-161
11. Lerner DJ, Kannel WB 1986 Patterns of coronary heart disease morbidity and mortality in the sexes: a 26-year followup of the Framingham population. Am Heart J 111:383-390
12. Holt EH, Lu C, Dreyer BE, Dannies PS, Broadus AE 1994 Regulation of parathyroid hormone-related peptide gene expression by estrogen in GH4C1 rat pituitary cells has the pattern of a primary response gene. J Neurochem 62:1239-1246
13. Cros M, Silve C, Graulet AM, Morieux C, Ureña P, de Vernejoul MC, Bouizar Z 1998 Estrogen stimulates PTHrP but not PTH/PTHrP receptor gene expression in the kidney of ovariectomized rat. J Cell Biochem 70:84-93
14. Chambliss KL, Shaul PW 2002 Estrogen modulation of endothelial nitric oxide synthase. Endocr Rev 23:665-686
15. Rosselli M, Imthurn B, Keller PJ, Jackson EK, Dubey RK 1995 Circulating nitric oxide (nitrite/nitrate) levels in postmenopausal women substituted with 17β-estradiol and norethisterone acetate. A two year follow-up study. Hypertension 25:848-853
16. Lagumdzija A, Ou G, Petersson M, Bucht E, Gonon A, Pernow Y 2004 Inhibited anabolic effect of insulin-like growth factor-I on stromal bone marrow cells in endothelial nitric oxide synthase-knockout mice. Acta Physiol Scand 182:29-35
17. Nuedling S, van Eickels M, Alléra A, Doevendans P, Meyer R, Vetter H, Grohé C 2003 17β Estradiol regulates the expression of endothelin receptor type B in the heart. BJP 140:195-201
18. Schlüter K-D, Piper HM 2005 Isolation and culture of adult ventricular cardiomyocytes. In: Dhein S, Mohr FM, Delmar M, eds. Practical methods in cardiovascular research. Berlin-Heidelberg: Springer Verlag; 557-567
19. Langer M, Lüttecke D, Schlüter K-D 2003 Mechanism of the positive contractile effect of nitric oxide on rat ventricular cardiomyocytes with positive force/frequency relationship. Eur J Physiol 447:289-297
20. Livak KJ, Schmittgen TD 2001 Analysis of relative gene expression data using real-time quantitative PCR and the 2[-δδ C(T)]. Methods 25:402-408
21. Nabulsi AA, Folsom AR, White A, Patsch W, Heiss G, Wu KK, Szko M 1993 Association of hormone-replacement therapy with various cardiovascular risk factors in postmenopausal women. N Engl J Med 328:1069-1075
22. Farhat MY, Lavigne MC, Ramwell PW 1996 The vascular protective effects of estrogen FASEB J 10:615-624
23. Walton C, Godsland IF, Proudler AJ, Wynn V, Stevenson JC 1993 The effects of the menopauseoninsulin sensitivity, secretion and elimination in non-obese, healthy women. Eur J Clin Invest 23:466-473
24. Smith PJ, Ornatsky O, Stewart DJ, Picard P, Dawood F, Wen WH, Liu PP, Webb DJ, Monge JC 2000 Effects of estrogen-replacement on infarct size, cardiac remodeling, and the endothelin system following myocardial infarction. Circulation 102:2983-2989
25. Patten RD, Karas RH 2006 Estrogen replacement and cardiomyocyte Protection. Trends Cardiovasc Med 16:69-75
26. McNeill AM, Zhang C, Stanczyk FZ, Duckles SP, Krause DN 2002 Estrogen increases endothelial nitric oxide synthase via estrogen receptors in rat cerebral blood vessels: effect preserved after concurrent treatment with medroxyprogesterone acetate or progesterone. Stroke 33:1685-1691
27. Loyer X, Damy T, Chvojkova Z, Robidel E, Marotte F, Oliviero P, Heymes C, Samuel JL 2007 17β-Estradiol regulates constitutive nitric oxide synthase expression differentially in the myocardium in response to pressure overload. Endocrinology 148:4579-4584
28. Schmidt A, Geigenmueller S, Voelker W, Seiler P, Buddecke E 2003 Exogenous nitric oxide causes overexpression of TGF-β1 and overproduction of extracellular matrix in human coronary smooth muscle cells. Cardiovasc Res 58:671-678
29. Abdelazis N, Colombo F, Mercier I, Calderone A 2001 Nitric oxide attenuates the expression of transforming growth factor-β3 mRNA in rat cardiac fibroblasts via destabilization. Hypertension 38:261-266
30. Wolf G, Ziyadeh FN, Stahl RA 1995 Atrial natriuretic peptide stimulates the expression of transforming growth factor-β in cultured murine mesangial cells: relationship to suppression of proliferation. J Am Soc Nephrol 6:224-233
31. Jongen JW, Willemstein-Van Hove EC, Van der Meer JM, Bos M, Jüppner H, Segre GV, Abou-Samra AB, Feyen J, Herrmann-Erlee MP 1995 Down regulation of the receptor for parathyroid hormone (PTH) and PTH-related peptide by transforming growth factor-β in primary fetal rat osteoblasts. Endocrinology 136:3260-3266
32. McCauley LK, Beecher CA, Melton ME, Werkmeister JR, Jüppner H, Abou Samara AB, Segre GV, Rosol TJ 1994 Transforming growth factor-β1 regulates steady-state PTH/PTHrP receptor mRNA levels and PTHrP binding in ROS 17/2.8 osteosarcoma cells. Mol Cell Endocrinol 101:331-336
33. Abdallah Y, Ross G, Dolf A, Heinemann MP, Schlüter KD 2006 N-terminal parathyroid hormone-related peptide hyperpolarizes endothelial cells and causes a reduction of the coronary resistance of the rat heart via endothelial hyperpolarization. Peptides 27:2927-2934