Parent's attitudes towards full-scale prenatal testing for genetic disorders

Journal of Psychosomatic Obstetrics and Gynecology

Volumn 30, Issue 1, 2009, Pages 42-47

  Pieters, Jacqueline J P M ^a   Kooper, Angelique J A ^b   Smits, Arie P T ^b   De Vries, Jolanda ^c  

^a IVF Centre Medisch Centrum Kinderwens   (Netherlands)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^c TILBURG UNIVERSITY   (Netherlands)

Author keywords

full scale testing; Parent's attitudes; prenatal diagnosis; targeted testing

Indexed keywords

ADULT; ARTICLE; CHILD; DEMOGRAPHY; DIAGNOSTIC TEST; DOWN SYNDROME; FEMALE; GENETIC ANALYSIS; GENETIC DISORDER; HIGH RISK PREGNANCY; HUMAN; MAJOR CLINICAL STUDY; MARITAL THERAPY; PARENTAL ATTITUDE; PREGNANT WOMAN; PRENATAL DIAGNOSIS; PROSPECTIVE STUDY; STRUCTURED QUESTIONNAIRE;

ADULT; ATTITUDE TO HEALTH; DOWN SYNDROME; FEMALE; GENETIC COUNSELING; GENETIC DISEASES, INBORN; GENETIC SCREENING; HUMANS; MALE; PARENTS; PROSPECTIVE STUDIES; QUESTIONNAIRES;

EID: 67651174355     PISSN: 0167482X     EISSN: 17438942     Source Type: Journal    
DOI: 10.1080/01674820802545842     Document Type: Article

References (23)

1. Minister of Health, letter to the Cabinet: CZ/IZ-2612095; 15 September 2005.
2. Wapner R, Thom E, Simpson JL, Pergament E, Silver R, Filkins K, et al. First trimester maternal serum biochemistry and fetal nuchal translucency screening (BUN) study group. First-trimester screening for trisomies 21 and 18. New Engl J Med 2003;349:1405-1413.
3. Nicolaides KH, Spencer K, Avgidou K, Faiola S, Falcon O, et al. Multicenter study of first-trimester screening for trisomy 21 in 75 821 pregnancies: results and estimation of the potential impact of individual risk-orientated two-stage first-trimester screening. Ultrasound Obstet Gynecol 2005;25:221-226.
4. Ellestad SC, Wells SR, Kuller JA. First trimester screening. Gynecol Obstet Invest 2005;60:58-62.
5. Wilson JA, Barton D. Targeted versus whole-genome array comparative genome hybridization: the Atlantic divide. J Mol Diagn 2007;9:278.
6. Veltman JA, Schoenmakers EF, Eussen BH, Janssen I, Merkx G, van Cleef B, et al. High-throughput analysis of subtelomeric chromosome rearrangements by use of array-based comparatative genomic hybridization. Am J Hum Genet 2002;70:1269-1276.
7. Veltman JA, de Vries BB. Whole-genome array comparative genome hybridisation: the preferred diagnostic choice in postnatal cytogenetics. J Mol Diagn 2007;9:277.
8. Schouten JP, McElgunn CJ, Waaijer R, Zwijnenburg D, Diepvens F, Pals G. Relative quantification of 40 nucleic acid sequences by multiplex ligation-dependent probe amplification. Nucleic Acids Res 2002;30:12 e57.
9. Slater HR, Bruno DL, Ren H, Pertile M, Schouten JP, Choo KH. Rapid, high throughput prenatal detection of aneuploidy using a novel quantitative method (MLPA). J Med Genet 2003;40:907-912.
10. Gerdes T, Kirchhoff M, Lind AM, Larsen GV, Schwartz M, Lundsteen C. Computer-assisted prenatal aneuploidy screening for chromosome 13, 18, 21, X and Y based on multiplex ligation-dependent probe amplification (MLPA). Eur J Hum Genet 2005;13:171-175.
11. Hochstenbach R, Meijer J, van de Brug J, Vossebeld-Hoff I, Jansen R, van der Luijt RB, et al. Rapid detection of chromosomal aneuploidies in uncultured amniocytes by multiplex ligation-dependent probe amplification (MLPA). Prenat Diagn 2005;25:1032-1039.
12. ZonMw feasibility study nr 5483. "M.A.K.E.: MLPA and karyotyping, an evaluation"; multicenter study in eight University Centres of Prenatal Diagnostics in the Netherlands; 2007;
13. Grody WW. Ethical issues raised by genetic testing with oligonucleotide microarrays. Mol Biotechnol 2003;23:127-138.
14. Lau TK, Leung TN. Genetic screening and diagnosis. Curr Opin Obstet Gynecol 2005;17:161-162.
15. The Ethox Centre; Department of Public Health & Primary Healthcare. Medical Sciences, University of Oxford, Oxford, UK; 2005. Specific ethical considerations relevant to genetic issues in healthcare. In: Medical Ethics Today - the BMA's handbook of ethics and law. BMJ Publishing Group; 2004. p. 308.
16. Michie S, French D, Allanson A, Bobrow M, Marteau TM. Information recall in genetic counselling: a pilot study of its assessment. Patient Educ Couns 1997;32:93-100.
17. Völler H, Dovifat C, Glatz J, Körtke H, Taborski U, Wegscheider K. Self management of oral anticoagulation with the IN ratio system: impact of a structured teaching program on patient's knowledge of medical background and procedures. Eur J Cardiovasc Prev Rehabil 2004;11:442-447.
18. Hoedjes M. Knowledge about prenatal screening and diagnostic tests. Masters' thesis, Department of Medical Psychology, Tilburg University; 2006.
19. Dormandy E, Michie S, Hooper R, Marteau TM. Low uptake of prenatal screening for Down syndrome in minority ethnic groups and socially deprived groups: a reflection of women's attitudes or a failure to facilitate informed choices? Int J Epidemiol 2005;34:346-352.
20. Baker H, Uus K, Bamford J, Marteau TM. Increasing knowledge about a screening test: preliminary evaluation of a structured, chart-based, screener presentation. Patient Educ Couns 2004;52:55-59.
21. Van den Berg M, Timmermans DR, Ten Kate LP, van Vugt JM, van der Wal G. Are pregnant women making informed choices about prenatal screening. Genet Med 2005;7:332-338.
22. Maat-Kievit A, Vegter-van der Vlis M, Zoeteweij M, Losekoot M, van Haeringen A, Kanhai H, et al. Experience in prenatal testing for Huntington's disease in the Netherlands: procedures, results and guidelines (1987-1997). Prenat Diagn 1999;19:450-457.
23. Redon R, Ishikawa S, Fitch KR, Feuk L, Perry GH, Andrews TD, et al. Global variation in copy number in the human genome. Nature 2006;444:444-454.