Extracorporeal shock-wave therapy enhanced wound healing via increasing topical blood perfusion and tissue regeneration in a rat model of STZ-induced diabetes

Wound Repair and Regeneration

Volumn 17, Issue 4, 2009, Pages 522-530

  Kuo, Yur Ren ^a,b   Wang, Chun Ting ^a,b   Wang, Feng Sheng ^b   Chiang, Yuan Cheng ^a   Wang, Ching Jen ^b  

^a CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

^b CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLINE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; INSULIN; VASCULOTROPIN;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHRONIC DISEASE; CONTROLLED STUDY; EXTRACORPOREAL LITHOTRIPSY; FLUORESCENCE MICROSCOPY; GLUCOSE BLOOD LEVEL; IMAGING SYSTEM; IMMUNOHISTOCHEMISTRY; LASER DOPPLER FLOWMETRY; MALE; MICROVASCULATURE; NONHUMAN; PRIORITY JOURNAL; RAT; SKIN BIOPSY; SKIN DEFECT; STREPTOZOCIN DIABETES; TISSUE PERFUSION; TISSUE REGENERATION; TREATMENT OUTCOME; WOUND HEALING; WOUND HEALING IMPAIRMENT;

ANIMALS; DIABETES MELLITUS, EXPERIMENTAL; DNA-BINDING PROTEINS; MALE; MICROCIRCULATION; PHOSPHOPYRUVATE HYDRATASE; PROLIFERATING CELL NUCLEAR ANTIGEN; RATS; RATS, WISTAR; SKIN; SKIN ULCER; TUMOR MARKERS, BIOLOGICAL; TUMOR SUPPRESSOR PROTEINS; ULTRASONIC THERAPY; VASCULAR ENDOTHELIAL GROWTH FACTOR A; WOUND HEALING;

EID: 67651173135     PISSN: 10671927     EISSN: 1524475X     Source Type: Journal    
DOI: 10.1111/j.1524-475X.2009.00504.x     Document Type: Article

References (25)

1. Most RS, Sinnock P. The epidemiology of lower extremity amputations in diabetic individuals. Diabetes Care 1983 6 : 87 91.
2. Cavanagh PR, Lipsky BA, Bradbury AW, Botek G. Treatment for diabetic foot ulcers. Lancet 2005 366 : 1725 35.
3. Holstein P, Ellitsgaard N, Olsen BB, Ellitsgaard V. Decreasing incidence of major amputations in people with diabetes. Diabetologia 2000 43 : 844 7.
4. Muhs BE, Gagne P, Sheehan P. Peripheral arterial disease: clinical assessment and indications for revascularization in the patient with diabetes. Curr Diab Rep 2005 5 : 24 9.
5. Fife CE, Buyukcakir C, Otto G, Sheffield P, Love T, Warriner R III. Factors influencing the outcome of lower-extremity diabetic ulcers treated with hyperbaric oxygen therapy. Wound Repair Regen 2007 15 : 322 31.
6. Prompers L, Huijberts M, Apelqvist J, Jude E, Piaggesi A, Bakker K, Edmonds M, Holstein P, Jirkovska A, Mauricio D, Ragnarson Tennvall G, Reike H, Spraul M, Uccioli L, Urbancic V, Van Acker K, van Baal J, van Merode F, Schaper N. High prevalence of ischaemia, infection and serious comorbidity in patients with diabetic foot disease in Europe. Baseline results from the Eurodiale study. Diabetologia 2007 50 : 18 25.
7. Brem H, Sheehan P, Rosenberg HJ, Schneider JS, Boulton AJ. Evidence-based protocol for diabetic foot ulcers. Plast Reconstr Surg 2006 117 : S193 209.
8. Harding KG, Jones V, Price P. Topical treatment: which dressing to choose. Diabetes Metab Res Rev 2000 16 : S47 50.
9. Roeckl-Wiedmann I, Bennett M, Kranke P. Systematic review of hyperbaric oxygen in the management of chronic wounds. Br J Surg 2005 92 : 24 32.
10. Brem H, Jacobs T, Vileikyte L, Weinberger S, Gibber M, Gill K, Tarnovskaya A, Entero H, Boulton AJ. Wound-healing protocols for diabetic foot and pressure ulcers. Surg Technol Int 2003 11 : 85 92.
11. Wang CJ. An overview of shock wave therapy in musculoskeletal disorders. Chang Gung Med J 2003 26 : 220 32.
12. Schaden W, Fischer A, Sailler A. Extracorporeal shock wave therapy of nonunion or delayed osseous union. Clin Orthop Relat Res 2001 387 : 90 4.
13. Bara T, Synder M. Nine-years experience with the use of shock waves for treatment of bone union disturbances. Ortop Traumatol Rehabil 2007 9 : 254 8.
14. Chen YJ, Wurtz T, Wang CJ, Kuo YR, Yang KD, Huang HC, Wang FS. Recruitment of mesenchymal stem cells and expression of TGF-beta 1 and VEGF in the early stage of shock wave-promoted bone regeneration of segmental defect in rats. J Orthop Res 2004 22 : 526 34.
15. Wang FS, Yang KD, Kuo YR, Wang CJ, Sheen-Chen SM, Huang HC, Chen YJ. Temporal and spatial expression of bone morphogenetic proteins in extracorporeal shock wave-promoted healing of segmental defect. Bone 2003 32 : 387 96.
16. Wang FS, Yang KD, Chen RF, Wang CJ, Sheen-Chen SM. Extracorporeal shock wave promotes growth and differentiation of bone-marrow stromal cells towards osteoprogenitors associated with induction of TGF-beta1. J Bone Joint Surg Br 2002 84 : 457 61.
17. Meirer R, Kamelger FS, Huemer GM, Wanner S, Piza-Katzer H. Extracorporal shock wave may enhance skin flap survival in an animal model. Br J Plast Surg 2005 58 : 53 7.
18. Meirer R, Kamelger FS, Piza-Katzer H. Shock wave therapy: an innovative treatment method for partial thickness burns. Burns 2005 31 : 921 2.
19. Schaden W, Thiele R, Kolpl C, Pusch M, Nissan A, Attinger CE, Maniscalco-Theberge ME, Peoples GE, Elster EA, Stojadinovic A. Shock wave therapy for acute and chronic soft tissue wounds: a feasibility study. J Surg Res 2007 143 : 1 12.
20. Kuo YR, Wu WS, Hsieh YL, Wang FS, Wang CT, Chiang YC, Wang CJ. Extracorporeal shock wave enhanced extended skin flap tissue survival via increase of topical blood perfusion and associated with suppression of tissue pro-inflammation. J Surg Res 2007 143 : 385 92.
21. Wang CJ, Kuo YR, Wu RW, Liu RT, Hsu CS, Wang FS, Yang KD. Extracorporeal shockwave treatment for chronic diabetic foot ulcers. J Surg Res 2008, in press.
22. Kuo YR, Wang FS, Jeng SF, Lutz BS, Huang HC, Yang KD. Nitrosoglutathione improves blood perfusion and flap survival by suppressing iNOS but protecting eNOS expression in the flap vessels after ischemia/reperfusion injury. Surgery 2004 135 : 437 46.
23. Kuo YR, Wu WS, Jeng SF, Huang HC, Yang KD, Sacks JM, Wang FS. Activation of ERK and p38 kinase mediated keloid fibroblast apoptosis after flashlamp pulsed-dye laser treatment. Lasers Surg Med 2005 36 : 31 7.
24. Beckman JA, Creager MA, Libby P. Diabetes and atherosclerosis: epidemiology, pathophysiology, and management. JAMA 2002 287 : 2570 81.
25. Meirer R, Brunner A, Deibl M, Oehlbauer M, Piza-Katzer H, Kamelger FS. Shock wave therapy reduces necrotic flap zones and induces VEGF expression in animal epigastric skin flap model. J Reconstr Microsurg 2007 23 : 231 6.