CCN2 protein is an announcing marker for cardiac remodeling following STZ-induced moderate hyperglycemia in mice

Pharmacological Reports

Volumn 61, Issue 3, 2009, Pages 496-503

  Kaminski, Karol A ^a   Szepietowska, Barbara ^a   Bonda, Tomasz ^a   Kozuch, Marcin ^a   Mencel, Joanna ^a   Małkowski, Andrzej ^a   Sobolewski, Krzysztof ^a   Kovalchuk, Oksana ^a   Chyczewski, Lech ^a   Szelachowska, Małgorzata ^a   Górska, Maria ^a   Musiał, Wodzimierz J ^a   Winnicka, Maria M ^a  

^a MEDICAL UNIVERSITY OF BIALYSTOK   (Poland)

Author keywords

CCN proteins; Diabetic cardiomyopathy; Heart; Hyperglycemia

Indexed keywords

ATRIAL NATRIURETIC FACTOR; CONNECTIVE TISSUE GROWTH FACTOR; GELATINASE A; RNA; STREPTOZOCIN; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; C57BL 6 MOUSE; CONTROLLED STUDY; DISEASE MARKER; ENZYME ACTIVITY; HEART HYPERTROPHY; HEART LEFT VENTRICLE SIZE; HEART MUSCLE FIBROSIS; HEART VENTRICLE REMODELING; HISTOPATHOLOGY; HYPERGLYCEMIA; INSULIN DEPENDENT DIABETES MELLITUS; MALE; MORPHOMETRICS; MOUSE; NONHUMAN; PROTEIN ANALYSIS; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING; ZYMOGRAPHY;

ANIMALS; ATRIAL NATRIURETIC FACTOR; BIOLOGICAL MARKERS; CARDIOMYOPATHIES; CCN INTERCELLULAR SIGNALING PROTEINS; CONNECTIVE TISSUE GROWTH FACTOR; DIABETES MELLITUS, EXPERIMENTAL; DISEASE MODELS, ANIMAL; HYPERGLYCEMIA; MALE; MATRIX METALLOPROTEINASE 2; MICE; MICE, INBRED C57BL; MYOCARDIUM; TRANSFORMING GROWTH FACTOR BETA1; VENTRICULAR REMODELING;

EID: 67651166739     PISSN: 22995684     EISSN: 22995684     Source Type: Journal    
DOI: 10.1016/S1734-1140(09)70092-1     Document Type: Article

References (24)

1. Aasum E, Belke DD, Severson DL, Riemersma RA, Cooper M, Andreassen M, Larsen TS: Cardiac function and metabolism in type 2 diabetic mice after treatment with BM 17.0744, a novel PPAR-alpha activator. Am J Physiol, 2002, 283, H949-957.
2. Aragno M, Mastrocola R, Alloatti G, Vercellinatto I, Bardini P, Geuna S, Catalano MG et al.: Oxidative stress triggers cardiac fibrosis in the heart of diabetic rats. Endocrinology, 2008, 149, 380-388.
3. Boudina S, Abel ED: Diabetic cardiomyopathy revisited. Circulation, 2007, 115, 3213-3223.
4. Brigstock DR: The CCN family: a new stimulus package. J Endocrinol, 2003, 178, 169-175.
5. Candido R, Forbes JM, Thomas MC, Thallas V, Dean RG, Burns WC, Tikellis C et al.: A breaker of advanced glycation end products attenuates diabetes-induced myocardial structural changes. Circ Res, 2003, 92, 785-792.
6. Csanyi G, Lepran I, Flesch T, Telegdy G, Szabo G, Mezei Z: Lack of endothelium-derived hyperpolarizing factor (EDHF) up-regulation in endothelial dysfunction in aorta in diabetic rats. Pharmacol Rep, 2007, 59, 447-455.
7. Fan WH, Pech M, Karnovsky MJ: Connective tissue growth factor (CTGF) stimulates vascular smooth muscle cell growth and migration in vitro. Eur J Cell Biol, 2000, 79, 915-923.
8. Fuchs M, Hilfiker A, Kaminski K, Hilfiker-Kleiner D, Guener Z, Klein G, Podewski E et al.: Role of interleukin-6 for LV remodeling and survival after experimental myocardial infarction. FASEB J, 2003, 17, 2118-2120.
9. Hayden MR, Chowdhury N, Govindarajan G, Karuparthi PR, Habibi J, Sowers JR: Myocardial myocyte remodeling and fibrosis in the cardiometabolic syndrome. J Cardiometab Syndr, 2006, 1, 326-333.
10. Hilfiker-Kleiner D, Kaminski K, Kaminska A, Fuchs M, Klein G, Podewski E, Grote K et al.: Regulation of proangiogenic factor CCN1 in cardiac muscle: impact of ischemia, pressure overload, and neurohumoral activation. Circulation, 2004, 109, 2227-2233.
11. Kamiński K, Szepietowska B, Szelachowska M, Karwowski W, Kozuch M, Leszczyńska A, Usowicz-Szaryńska Met al.: Chronic moderate hyperglycaemia does not affect early infarct size or mortality after myocardial infarction in mice: preliminary results. Exp Clin Diabetol, 2006, 6, 309-313.
12. Kamiński K, Usowicz-Szaryńska M, Kozuch M, Bonda T, Karwowski W, Chyczewski L, Sawicki B et al.: Preconditioning with the low dose of lipopolysaccharide attenuates apoptosis in heart during septic shock in mice. Pharmacol Rep 2007, 59, Suppl 1, 161-166.
13. Kralik PM, Ye G, Metreveli NS, Shem X, Epstein PN: Cardiomyocyte dysfunction in models of type 1 and type 2 diabetes. Cardiovasc Toxicol, 2005, 5, 285-292.
14. Li B, Li Q, Wang X, Jana KP, Redaelli G, Kajstura J, Anversa P: Coronary constriction impairs cardiac function and induces myocardial damage and ventricular remodeling in mice. Am J Physiol, 1997, 273, H2508-2519.
15. 2 agonist) on Cyr61 and connective tissue growth factor gene expression. J Biol Chem, 2003, 278, 27267-27277.
16. T method. Methods, 2001, 25, 402-408.
17. McLennan SV, Wang XY, Moreno V, Yue DK, Twigg SM: Connective tissue growth factor mediates high glucose effects on matrix degradation through tissue inhibitor of matrix metalloproteinase type 1: implications for diabetic nephropathy. Endocrinology, 2004, 145, 5646-5655.
18. Moussad EE, Brigstock DR: Connective tissue growth factor: what's in a name? Mol Genet Metab, 2000, 71, 276-292.
19. Pacher P, Liaudet L, Soriano FG, Mabley JG, Szabo E, Szabo C: The role of poly(ADP-ribose) polymerase activation in the development of myocardial and endothelial dysfunction in diabetes. Diabetes, 2002, 51, 514-521.
20. Poornima IG, Parikh P, Shannon RP: Diabetic cardiomyopathy: the search for a unifying hypothesis. Circ Res, 2006, 98, 596-605.
21. Shiomi T, Tsutsui H, Ikeuchi M, Matsusaka H, Hayashidani S, Suematsu N, Wen J et al.: Streptozotocin-induced hyperglycemia exacerbates left ventricular remodeling and failure after experimental myocardial infarction. J Am Coll Cardiol, 2003, 42, 165-172.
22. Sobolewski K, Malkowski A, Bankowski E, Jaworski S: Wharton's jelly as a reservoir of peptide growth factors. Placenta, 2005, 26, 747-752.
23. Way KJ, Isshiki K, Suzuma K, Yokota T, Zvagelsky D, Schoen FJ, Sandusky GE et al.: Expression of connective tissue growth factor is increased in injured myocardium associated with protein kinase 2 activation and diabetes. Diabetes, 2002, 51, 2709-2718.
24. Westermann D, Rutschow S, Jager S, Linderer A, Anker S, Riad A, Unger T et al.: Contributions of inflammation and cardiac matrix metalloproteinase activity to cardiac failure in diabetic cardiomyopathy: the role of angiotensin type 1 receptor antagonism. Diabetes, 2007, 56, 641-646.