Prediction of vertebral strength under loading conditions occurring in activities of daily living using a computed tomography-based nonlinear finite element method

Spine

Volumn 34, Issue 14, 2009, Pages 1464-1469

  Matsumoto, Takuya ^a   Ohnishi, Isao ^a   Bessho, Masahiko ^a   Imai, Kazuhiro ^a,b   Ohashi, Satoru ^a   Nakamura, Kozo ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b Tokyo Metropolitan Institute of Gerontology   (Japan)

Author keywords

Fracture site; Fracture strength prediction; Nonlinear finite element analysis; Osteoporosis; Vertebral fracture

Indexed keywords

ADULT; AGED; ARTICLE; AXIS; BONE BOWING; BONE STRENGTH; CLINICAL ARTICLE; COMPRESSION; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; DAILY LIFE ACTIVITY; EVALUATION; FEMALE; FINITE ELEMENT ANALYSIS; HUMAN; LOADING TEST; LUMBAR VERTEBRA; MATHEMATICAL MODEL; POSTMENOPAUSE OSTEOPOROSIS; PREDICTION; PRIORITY JOURNAL; REGRESSION ANALYSIS; STANDING; VERTEBRA BODY; VERTEBRA FRACTURE;

ACTIVITIES OF DAILY LIVING; AGED; AGED, 80 AND OVER; BIOMECHANICS; COMPRESSIVE STRENGTH; FEMALE; FINITE ELEMENT ANALYSIS; FRACTURES, BONE; HUMANS; MIDDLE AGED; MODELS, BIOLOGICAL; OSTEOPOROSIS, POSTMENOPAUSAL; PROGNOSIS; SPINE; STRESS, MECHANICAL; TOMOGRAPHY, X-RAY COMPUTED; WEIGHT-BEARING;

EID: 67651162054     PISSN: 03622436     EISSN: 15281159     Source Type: Journal    
DOI: 10.1097/BRS.0b013e3181a55636     Document Type: Article

References (30)

1. NIH Consensus Development Panel on Osteoporosis prevention, diagnosis, and therapy. JAMA 2001;285:785-795
2. Melton LJ III, Chrischilles EA, Cooper C, et al. Perspective. How many women have osteoporosis? J Bone Miner Res 1992;7:1005-1010
3. Eastell R, Cedel SL, Wahner HW, et al. Classification of vertebral fractures. J Bone Miner Res 1991;6:207-215
4. Melton LJ III, Lane AW, Cooper C, et al. Prevalence and incidence of vertebral deformities. Osteoporos Int 1993;3:113-119
5. Granhed H, Jonson R, Hansson T. Mineral content and strength of lumbar vertebrae. A cadaver study. Acta Orthop Scand 1989;60:105-109 (Pubitemid 19090573)
6. Whealan KM, Kwak SD, Tedrow JR, et al. Noninvasive imaging predicts failure load of the spine with simulated osteolytic defects. J Bone Joint Surg Am 2000;82:1240-1251
7. Imai K, Ohnishi I, Bessho M, et al. Nonlinear finite element model predicts vertebral bone strength and fracture site. Spine 2006;31:1789-1794 (Pubitemid 44079505)
8. Imai K, Ohnishi I, Yamamoto S, et al. In vivo assessment of lumbar vertebral strength in elderly women using computed tomography-based nonlinear fi- nite element model. Spine 2008;33:27-32.
9. Bessho M, Ohnishi I, Matsuyama J, et al. Prediction of strength and strain of the proximal femur by a CT-based finite element method. J Biomech 2007;40:1745-1753 (Pubitemid 46702134)
10. Keyak JH, Rossi SA, Jones KA, et al. Prediction of femoral fracture load using automated finite element modeling. J Biomech 1998;31:125-133
11. Jensen KS, Mosekilde L, Mosekilde L. A model of vertebral trabecular bone architecture and its mechanical properties. Bone 1990;11:417-423
12. Rho JY, Tsui TY, Pharr GM. Elastic properties of human cortical and trabecular lamellar bone measured by nanoindentation. Biomaterials 1997;18:1325-1330
13. Hou FJ, Lang SM, Hoshaw SJ, et al. Human vertebral body apparent and hard tissue stiffness. J Biomech 1998;31:1009-1015
14. Ladd AJ, Kinney JH, Haupt DL, et al. Finite-element modeling of trabecular bone: comparison with mechanical testing and determination of tissue modulus. J Orthop Res 1998;16:622-628
15. Pollintine P, Dolan P, Tobias JH, et al. Intervertebral disc degeneration can lead to "stress-shielding" of the anterior vertebral body: a cause of osteoporotic vertebral fracture? Spine 2004;29:774-782
16. Oda K, Shibayama Y, Abe M, et al. Morphogenesis of vertebral deformities in involutional osteoporosis. Age-related, three-dimensional trabecular structure. Spine 1998;23:1050-5; discussion 6. (Pubitemid 28242005)
17. Wilke HJ, Neef P, Caimi M, et al. New in vivo measurements of pressures in the intervertebral disc in daily life. Spine 1999;24:755-762 (Pubitemid 29181527)
18. Keller TS, Ziv I, Moeljanto E, et al. Interdependence of lumbar disc and subdiscal bone properties: a report of the normal and degenerated spine. J Spinal Disord 1993;6:106-113 (Pubitemid 23113636)
19. Adams MA, Pollintine P, Tobias JH, et al. Intervertebral disc degeneration can predispose to anterior vertebral fractures in the thoracolumbar spine. J Bone Miner Res 2006;21:1409-1416 (Pubitemid 44300047)
20. Simpson EK, Parkinson IH, Manthey B, et al. Intervertebral disc disorganization is related to trabecular bone architecture in the lumbar spine. J Bone Miner Res 2001;16:681-687 (Pubitemid 32230596)
21. Kurowski P, Kubo A. The relationship of degeneration of the intervertebral disc to mechanical loading conditions on lumbar vertebrae. Spine 1986;11:726-731 (Pubitemid 17170429)
22. Buckley JM, Cheng L, Loo K, et al. Quantitative computed tomography-based predictions of vertebral strength in anterior bending. Spine 2007;32:1019-1027 (Pubitemid 46642560)
23. Crawford RP, Keaveny TM. Relationship between axial and bending behaviors of the human thoracolumbar vertebra. Spine 2004;29:2248-2255
24. Crawford RP, Rosenberg WS, Keaveny TM. Quantitative computed tomography- based finite element models of the human lumbar vertebral body: effect of element size on stiffness, damage, and fracture strength predictions. J Biomech Eng 2003;125:434-438
25. Bouxsein ML, Melton LJ III, Riggs BL, et al. Age- and sex-specific differences in the factor of risk for vertebral fracture: a population-based study using QCT. J Bone Miner Res 2006;21:1475-1482
26. Schultz AB, Andersson GB. Analysis of loads on the lumbar spine. Spine 1981;6:76-82.
27. Keaveny TM, Donley DW, Hoffmann PF, et al. Effects of teriparatide and alendronate on vertebral strength as assessed by finite element modeling of QCT scans in women with osteoporosis. J Bone Miner Res 2007;22:149-157
28. Imai K, Ohnishi I, Matsumoto T, et al. Assessment of vertebral fracture risk and therapeutic effects of alendronate in postmenopausal women using a quantitative computed tomography-based nonlinear finite element method. Osteoporos Int 2008;19:383-384
29. Chen SI, Lin RM, Chang CH. Biomechanical investigation of pedicle screw-vertebrae complex: a finite element approach using bonded and contact interface conditions. Med Eng Phys 2003;25:275-282
30. Chevalier Y, Pahr D, Charlebois M, et al. Cement distribution, volume, and compliance in vertebroplasty: some answers from an anatomy-based nonlinear finite element study. Spine 2008;33:1722-1730