메뉴 건너뛰기




Volumn 5, Issue 3, 2009, Pages 251-262

Adjuvant systemic therapy for older adults with early-stage breast cancer

Author keywords

Adjuvant; Bisphosphonate; Breast cancer; Chemotherapy; Endocrine therapy; Estrogen receptor; HER2; Progesterone receptor; Trastuzumab

Indexed keywords

ANASTROZOLE; ANTHRACYCLINE; BISPHOSPHONIC ACID DERIVATIVE; CAPECITABINE; CARBOPLATIN; CYCLOPHOSPHAMIDE; DOCETAXEL; DOXORUBICIN; EPIDERMAL GROWTH FACTOR RECEPTOR 2; EPIRUBICIN; ESTROGEN RECEPTOR; FLUOROURACIL; LETROZOLE; METHOTREXATE; PLACEBO; PROGESTERONE RECEPTOR; TAMOXIFEN; TRASTUZUMAB; ANTINEOPLASTIC AGENT;

EID: 67651160734     PISSN: 17455057     EISSN: 17455065     Source Type: Journal    
DOI: 10.2217/whe.09.17     Document Type: Review
Times cited : (3)

References (68)
  • 2
    • 0033619959 scopus 로고    scopus 로고
    • Underrepresentation of patients 65 years of age or older in cancer-treatment trials
    • Hutchins LF, Unger JM, Crowley JJ et al.: Underrepresentation of patients 65 years of age or older in cancer-treatment trials. N. Engl. J. Med. 341, 2061-2067 (1999).
    • (1999) N. Engl. J. Med , vol.341 , pp. 2061-2067
    • Hutchins, L.F.1    Unger, J.M.2    Crowley, J.J.3
  • 3
    • 62549131714 scopus 로고    scopus 로고
    • The cancer survival gap between elderly and middle-aged patients in Europe is widening
    • DOI: 10.1016/j.ejca.2008.11.028
    • Quaglia A, Tavilla A, Shack L et al.: The cancer survival gap between elderly and middle-aged patients in Europe is widening. Eur. J. Cancer. DOI: 10.1016/j.ejca.2008.11.028 (2008)
    • (2008) Eur. J. Cancer
    • Quaglia, A.1    Tavilla, A.2    Shack, L.3
  • 4
    • 34247249783 scopus 로고    scopus 로고
    • Surgery, with or without tamoxifen, vs tamoxifen alone for older women with operable breast cancer: Cochrane review
    • Hind D, Wyld L, Reed MW: Surgery, with or without tamoxifen, vs tamoxifen alone for older women with operable breast cancer: Cochrane review. Br. J. Cancer 96, 1025-1029 (2007).
    • (2007) Br. J. Cancer , vol.96 , pp. 1025-1029
    • Hind, D.1    Wyld, L.2    Reed, M.W.3
  • 5
    • 4344628403 scopus 로고    scopus 로고
    • Lumpectomy plus tamoxifen with or without irradiation in women 70 years of age or older with early breast cancer
    • Hughes KS, Schnaper LA, Berry D et al.: Lumpectomy plus tamoxifen with or without irradiation in women 70 years of age or older with early breast cancer. N. Engl. J. Med. 351, 971-977 (2004).
    • (2004) N. Engl. J. Med , vol.351 , pp. 971-977
    • Hughes, K.S.1    Schnaper, L.A.2    Berry, D.3
  • 6
    • 35348900040 scopus 로고    scopus 로고
    • Older women with operable breast cancer are less likely to have surgery
    • Lavelle K, Moran A, Howell A et al.: Older women with operable breast cancer are less likely to have surgery. Br. J. Surg. 94, 1209-1215 (2007).
    • (2007) Br. J. Surg , vol.94 , pp. 1209-1215
    • Lavelle, K.1    Moran, A.2    Howell, A.3
  • 7
    • 33750615608 scopus 로고    scopus 로고
    • Postmastectomy radiation and survival in older women with breast cancer
    • Smith BD, Haffty BG, Hurria A et al.: Postmastectomy radiation and survival in older women with breast cancer. J. Clin. Oncol. 24, 4901-4907 (2006).
    • (2006) J. Clin. Oncol , vol.24 , pp. 4901-4907
    • Smith, B.D.1    Haffty, B.G.2    Hurria, A.3
  • 8
    • 19344364880 scopus 로고    scopus 로고
    • Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: An overview of the randomised trials
    • Early Breast Cancer Trialists Collaborative Group
    • Early Breast Cancer Trialists Collaborative Group: Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials. Lancet 365, 1687-1717 (2005).
    • (2005) Lancet , vol.365 , pp. 1687-1717
  • 9
    • 20044388527 scopus 로고    scopus 로고
    • Adjuvant chemotherapy in older and younger women with lymph node-positive breast cancer
    • Muss HB, Woolf S, Berry D et al.: Adjuvant chemotherapy in older and younger women with lymph node-positive breast cancer. JAMA 293, 1073-1081 (2005).
    • (2005) JAMA , vol.293 , pp. 1073-1081
    • Muss, H.B.1    Woolf, S.2    Berry, D.3
  • 10
    • 33745582063 scopus 로고    scopus 로고
    • Adjuvant chemotherapy and survival in older women with hormone receptor-negative breast cancer: Assessing outcome in a population-based, observational cohort
    • Elkin EB, Hurria A, Mitra N et al.: Adjuvant chemotherapy and survival in older women with hormone receptor-negative breast cancer: assessing outcome in a population-based, observational cohort. J. Clin. Oncol. 24, 2757-2764 (2006).
    • (2006) J. Clin. Oncol , vol.24 , pp. 2757-2764
    • Elkin, E.B.1    Hurria, A.2    Mitra, N.3
  • 11
    • 33745528525 scopus 로고    scopus 로고
    • Use and outcomes of adjuvant chemotherapy in older women with breast cancer
    • Giordano SH, Duan Z, Kuo Y-F et al.: Use and outcomes of adjuvant chemotherapy in older women with breast cancer. J. Clin. Oncol. 24, 2750-2756 (2006).
    • (2006) J. Clin. Oncol , vol.24 , pp. 2750-2756
    • Giordano, S.H.1    Duan, Z.2    Kuo, Y.-F.3
  • 12
    • 16544369385 scopus 로고    scopus 로고
    • Disease-free survival advantage of weekly epirubicin plus tamoxifen versus tamoxifen alone as adjuvant treatment of operable, node-positive, elderly breast cancer patients: 6-year follow-up results of the French adjuvant study group 08 trial
    • Fargeot P, Bonneterre J, Roche H et al.: Disease-free survival advantage of weekly epirubicin plus tamoxifen versus tamoxifen alone as adjuvant treatment of operable, node-positive, elderly breast cancer patients: 6-year follow-up results of the French adjuvant study group 08 trial. J. Clin. Oncol. 22, 4674-4682 (2004).
    • (2004) J. Clin. Oncol , vol.22 , pp. 4674-4682
    • Fargeot, P.1    Bonneterre, J.2    Roche, H.3
  • 13
    • 46849094497 scopus 로고    scopus 로고
    • Standard chemotherapy (CMF or AC) versus capecitabine in early-stage breast cancer (BC) patients aged 65 and older: Results of CALGB/CTSU 49907
    • Muss HB, Berry DL, Cirrincione C et al.: Standard chemotherapy (CMF or AC) versus capecitabine in early-stage breast cancer (BC) patients aged 65 and older: results of CALGB/CTSU 49907. J. Clin. Oncol. 26 (2008).
    • (2008) J. Clin. Oncol , vol.26
    • Muss, H.B.1    Berry, D.L.2    Cirrincione, C.3
  • 14
    • 20244368234 scopus 로고    scopus 로고
    • Safety and efficacy of two different doses of capecitabine in the treatment of advanced breast cancer in older women
    • Bajetta E, Procopio G, Celio L et al.: Safety and efficacy of two different doses of capecitabine in the treatment of advanced breast cancer in older women. J. Clin. Oncol. 23, 2155-2161 (2005).
    • (2005) J. Clin. Oncol , vol.23 , pp. 2155-2161
    • Bajetta, E.1    Procopio, G.2    Celio, L.3
  • 15
    • 50249110527 scopus 로고    scopus 로고
    • Extended follow-up and ana lysis by age of the US oncology adjuvant trial 9735: Docetaxel/ cyclophosphamide is associated with an overall survival benefit compared with doxorubicin/cyclophosphamide and is well-tolerated in women 65 or older
    • Jones S, Holmes F, O'Shaughnessy J et al.: Extended follow-up and ana lysis by age of the US oncology adjuvant trial 9735: docetaxel/ cyclophosphamide is associated with an overall survival benefit compared with doxorubicin/cyclophosphamide and is well-tolerated in women 65 or older. Breast Cancer Res. Treat. (2008).
    • (2008) Breast Cancer Res. Treat
    • Jones, S.1    Holmes, F.2    O'Shaughnessy, J.3
  • 16
    • 34548484358 scopus 로고    scopus 로고
    • Toxicity of older and younger patients treated with adjuvant chemotherapy for node-positive breast cancer: The cancer and leukemia group B experience
    • Muss HB, Berry DA, Cirrincione C et al.: Toxicity of older and younger patients treated with adjuvant chemotherapy for node-positive breast cancer: the cancer and leukemia group B experience. J. Clin. Oncol. 25, 3699-3704 (2007).
    • (2007) J. Clin. Oncol , vol.25 , pp. 3699-3704
    • Muss, H.B.1    Berry, D.A.2    Cirrincione, C.3
  • 17
    • 34548535264 scopus 로고    scopus 로고
    • Acute myeloid leukemia after adjuvant breast cancer therapy in older women: Understanding risk
    • Patt DA, Duan Z, Fang S et al.: Acute myeloid leukemia after adjuvant breast cancer therapy in older women: understanding risk. J. Clin. Oncol. 25, 3871-3876 (2007).
    • (2007) J. Clin. Oncol , vol.25 , pp. 3871-3876
    • Patt, D.A.1    Duan, Z.2    Fang, S.3
  • 18
    • 0033542851 scopus 로고    scopus 로고
    • Mortality during adjuvant treatment of early breast cancer with cyclophosphamide, methotrexate, and fluorouracil
    • Colleoni M, Price KN, Castiglione-Gertsch M et al.: Mortality during adjuvant treatment of early breast cancer with cyclophosphamide, methotrexate, and fluorouracil. Lancet 354, 130-131 (1999).
    • (1999) Lancet , vol.354 , pp. 130-131
    • Colleoni, M.1    Price, K.N.2    Castiglione-Gertsch, M.3
  • 19
    • 33745989223 scopus 로고    scopus 로고
    • 2006 update of recommendations for the use of white blood cell growth factors: An evidence-based clinical practice guideline
    • Smith TJ, Khatcheressian J, Lyman GH et al.: 2006 update of recommendations for the use of white blood cell growth factors: an evidence-based clinical practice guideline. J. Clin. Oncol. 24, 3187-3205 (2006).
    • (2006) J. Clin. Oncol , vol.24 , pp. 3187-3205
    • Smith, T.J.1    Khatcheressian, J.2    Lyman, G.H.3
  • 20
    • 49249135889 scopus 로고    scopus 로고
    • Anthracycline cardiotoxicity: From bench to bedside
    • Gianni L, Herman EH, Lipshultz SE et al.: Anthracycline cardiotoxicity: from bench to bedside. J. Clin. Oncol. 26, 3777-3784 (2008).
    • (2008) J. Clin. Oncol , vol.26 , pp. 3777-3784
    • Gianni, L.1    Herman, E.H.2    Lipshultz, S.E.3
  • 21
    • 33644840267 scopus 로고    scopus 로고
    • Chemotherapy and cardiotoxicity in older breast cancer patients: A population-based study
    • Doyle JJ, Neugut AI, Jacobson JS et al.: Chemotherapy and cardiotoxicity in older breast cancer patients: a population-based study. J. Clin. Oncol. 23, 8597-8605 (2005).
    • (2005) J. Clin. Oncol , vol.23 , pp. 8597-8605
    • Doyle, J.J.1    Neugut, A.I.2    Jacobson, J.S.3
  • 22
    • 68349152088 scopus 로고    scopus 로고
    • Giordano SH, Pinder M, Duan Z et al.: Congestive heart failure (CHF) in older women treated with anthracycline (A) chemotherapy (C). ASCO Annual Meeting Proceedings Part I. J. Clin. Oncol. 24(18S), 521 (2006).
    • Giordano SH, Pinder M, Duan Z et al.: Congestive heart failure (CHF) in older women treated with anthracycline (A) chemotherapy (C). ASCO Annual Meeting Proceedings Part I. J. Clin. Oncol. 24(18S), 521 (2006).
  • 23
    • 33746866643 scopus 로고    scopus 로고
    • Effect of adjuvant breast cancer chemotherapy on cognitive function from the older patient's perspective
    • Hurria A, Goldfarb S, Rosen C et al.: Effect of adjuvant breast cancer chemotherapy on cognitive function from the older patient's perspective. Breast. Cancer Res. Treat. 98, 343-348 (2006).
    • (2006) Breast. Cancer Res. Treat , vol.98 , pp. 343-348
    • Hurria, A.1    Goldfarb, S.2    Rosen, C.3
  • 24
    • 54049121065 scopus 로고    scopus 로고
    • Effect of a dementia diagnosis on survival of older patients after a diagnosis of breast, colon, or prostate cancer: Implications for cancer care
    • Raji MA, Kuo Y-F, Freeman JL et al.: Effect of a dementia diagnosis on survival of older patients after a diagnosis of breast, colon, or prostate cancer: implications for cancer care. Arch. Intern. Med. 168, 2033-2040 (2008).
    • (2008) Arch. Intern. Med , vol.168 , pp. 2033-2040
    • Raji, M.A.1    Kuo, Y.-F.2    Freeman, J.L.3
  • 25
    • 34250845521 scopus 로고    scopus 로고
    • Effectiveness of adjuvant tamoxifen therapy among older women with early stage breast cancer
    • Owusu C, Lash TL, Silliman RA: Effectiveness of adjuvant tamoxifen therapy among older women with early stage breast cancer. Breast J. 13, 374-382 (2007).
    • (2007) Breast J , vol.13 , pp. 374-382
    • Owusu, C.1    Lash, T.L.2    Silliman, R.A.3
  • 26
    • 39149107837 scopus 로고    scopus 로고
    • Predictors of tamoxifen discontinuation among older women with estrogen receptor-positive breast cancer
    • Owusu C, Buist DSM, Field TS et al.: Predictors of tamoxifen discontinuation among older women with estrogen receptor-positive breast cancer. J. Clin. Oncol. 26, 549-555 (2008).
    • (2008) J. Clin. Oncol , vol.26 , pp. 549-555
    • Owusu, C.1    Buist, D.S.M.2    Field, T.S.3
  • 27
    • 4344667475 scopus 로고    scopus 로고
    • Patient beliefs and tamoxifen discontinuance in older women with estrogen receptor - positive breast cancer
    • Fink AK, Gurwitz J, Rakowski W et al.: Patient beliefs and tamoxifen discontinuance in older women with estrogen receptor - positive breast cancer. J. Clin. Oncol. 22, 3309-3315 (2004).
    • (2004) J. Clin. Oncol , vol.22 , pp. 3309-3315
    • Fink, A.K.1    Gurwitz, J.2    Rakowski, W.3
  • 28
    • 3142783607 scopus 로고    scopus 로고
    • The relationship among physicians' specialty, perceptions of the risks and benefits of adjuvant tamoxifen therapy, and its recommendation in older patients with breast cancer
    • Malek K, Fink AK, Thwin SS et al.: The relationship among physicians' specialty, perceptions of the risks and benefits of adjuvant tamoxifen therapy, and its recommendation in older patients with breast cancer. Med. Care 42, 700-706 (2004).
    • (2004) Med. Care , vol.42 , pp. 700-706
    • Malek, K.1    Fink, A.K.2    Thwin, S.S.3
  • 29
    • 37449028688 scopus 로고    scopus 로고
    • Effect of anastrozole and tamoxifen as adjuvant treatment for early-stage breast cancer: 100-month ana lysis of the ATAC trial
    • Forbes JF, Cuzick J, Buzdar A et al.: Effect of anastrozole and tamoxifen as adjuvant treatment for early-stage breast cancer: 100-month ana lysis of the ATAC trial. Lancet Oncol. 9, 45-53 (2008).
    • (2008) Lancet Oncol , vol.9 , pp. 45-53
    • Forbes, J.F.1    Cuzick, J.2    Buzdar, A.3
  • 30
    • 65749105712 scopus 로고    scopus 로고
    • BIG 1-98: A randomized double-blind Phase III study evaluating letrozole and tamoxifen given in sequence as adjuvant endocrine therapy for postmenopausal women with receptor-positive breast cancer
    • Mouridsen HT, Giobbie-Hurder A, Mauriac L et al.: BIG 1-98: A randomized double-blind Phase III study evaluating letrozole and tamoxifen given in sequence as adjuvant endocrine therapy for postmenopausal women with receptor-positive breast cancer Breast Cancer Res. Treat. (2009).
    • (2009) Breast Cancer Res. Treat
    • Mouridsen, H.T.1    Giobbie-Hurder, A.2    Mauriac, L.3
  • 31
    • 42949164467 scopus 로고    scopus 로고
    • Letrozole compared with tamoxifen for elderly patients with endocrine-responsive early breast cancer: The BIG 1-98 trial
    • Crivellari D, Sun Z, Coates AS et al.: Letrozole compared with tamoxifen for elderly patients with endocrine-responsive early breast cancer: the BIG 1-98 trial. J. Clin. Oncol. 26, 1972-1979 (2008).
    • (2008) J. Clin. Oncol , vol.26 , pp. 1972-1979
    • Crivellari, D.1    Sun, Z.2    Coates, A.S.3
  • 32
    • 0035795683 scopus 로고    scopus 로고
    • Five versus more than five years of tamoxifen for lymph node-negative breast cancer: Updated findings from the national surgical adjuvant breast and bowel project B-14 randomized trial
    • Fisher B, Dignam J, Bryant J et al.: Five versus more than five years of tamoxifen for lymph node-negative breast cancer: updated findings from the national surgical adjuvant breast and bowel project B-14 randomized trial. J. Natl Cancer Inst. 93, 684-690 (2001).
    • (2001) J. Natl Cancer Inst , vol.93 , pp. 684-690
    • Fisher, B.1    Dignam, J.2    Bryant, J.3
  • 33
    • 59949092603 scopus 로고    scopus 로고
    • aTTom (adjuvant tamoxifen - to offer more?): Randomized trial of 10 versus 5 years of adjuvant tamoxifen among 6,934 women with estrogen receptor-positive (ER+) or ER untested breast cancer - preliminary results
    • Gray RG, Rea DW, Handley K et al.: aTTom (adjuvant tamoxifen - to offer more?): randomized trial of 10 versus 5 years of adjuvant tamoxifen among 6,934 women with estrogen receptor-positive (ER+) or ER untested breast cancer - preliminary results. J. Clin. Oncol. 26 (2008).
    • (2008) J. Clin. Oncol , vol.26
    • Gray, R.G.1    Rea, D.W.2    Handley, K.3
  • 34
    • 58249095481 scopus 로고    scopus 로고
    • ATLAS (Adjuvant tamoxifen, longer against shorter): International randomized trial of 10 versus 5 years of adjuvant tamoxifen among 11 500 women preliminary results
    • on Behalf of the ATLAS Collaboration
    • Peto R, Davies C, on Behalf of the ATLAS Collaboration: ATLAS (Adjuvant tamoxifen, longer against shorter): international randomized trial of 10 versus 5 years of adjuvant tamoxifen among 11 500 women preliminary results. Breast Cancer Res. Treat. (2008).
    • (2008) Breast Cancer Res. Treat
    • Peto, R.1    Davies, C.2
  • 35
    • 34249936011 scopus 로고    scopus 로고
    • Efficacy of letrozole extended adjuvant therapy according to estrogen receptor and progesterone receptor status of the primary tumor: National cancer institute of Canada clinical trials group MA.17
    • Goss PE, Ingle JN; Martino S et al.: Efficacy of letrozole extended adjuvant therapy according to estrogen receptor and progesterone receptor status of the primary tumor: national cancer institute of Canada clinical trials group MA.17. J. Clin. Oncol. 25, 2006-2011 (2007).
    • (2007) J. Clin. Oncol , vol.25 , pp. 2006-2011
    • Goss, P.E.1    Ingle, J.N.2    Martino, S.3
  • 36
    • 42949108170 scopus 로고    scopus 로고
    • Efficacy, toxicity, and quality of life in older women with early-stage breast cancer treated with letrozole or placebo after 5 years of tamoxifen: NCIC CTG intergroup trial MA.17
    • Muss HB, Tu D, Ingle JN et al.: Efficacy, toxicity, and quality of life in older women with early-stage breast cancer treated with letrozole or placebo after 5 years of tamoxifen: NCIC CTG intergroup trial MA.17. J. Clin. Oncol. 26, 1956-1964 (2008).
    • (2008) J. Clin. Oncol , vol.26 , pp. 1956-1964
    • Muss, H.B.1    Tu, D.2    Ingle, J.N.3
  • 37
    • 33746408229 scopus 로고    scopus 로고
    • Comprehensive side-effect profile of anastrozole and tamoxifen as adjuvant treatment for early-stage breast cancer: Long-term safety ana lysis of the ATAC trial
    • Buzdar A, Howell A, Cuzick J et al.: Comprehensive side-effect profile of anastrozole and tamoxifen as adjuvant treatment for early-stage breast cancer: long-term safety ana lysis of the ATAC trial. Lancet Oncol. 7, 633-643 (2006).
    • (2006) Lancet Oncol , vol.7 , pp. 633-643
    • Buzdar, A.1    Howell, A.2    Cuzick, J.3
  • 38
    • 0029833720 scopus 로고    scopus 로고
    • The effect of tamoxifen and hormone replacement therapy on serum cholesterol, bone mineral density and coagulation factors in healthy postmenopausal women participating in a randomised, controlled tamoxifen prevention study
    • Chang J, Powles TJ, Ashley SE et al.: The effect of tamoxifen and hormone replacement therapy on serum cholesterol, bone mineral density and coagulation factors in healthy postmenopausal women participating in a randomised, controlled tamoxifen prevention study. Ann. Oncol. 7, 671-675 (1996).
    • (1996) Ann. Oncol , vol.7 , pp. 671-675
    • Chang, J.1    Powles, T.J.2    Ashley, S.E.3
  • 39
    • 0037172407 scopus 로고    scopus 로고
    • Pathogenesis of bone fragility in women and men
    • Seeman E: Pathogenesis of bone fragility in women and men. Lancet 359, 1841-1850 (2002).
    • (2002) Lancet , vol.359 , pp. 1841-1850
    • Seeman, E.1
  • 40
    • 46849110780 scopus 로고    scopus 로고
    • Practical guidance for the management of aromatase inhibitor-associated bone loss
    • Hadji P, Body J-J, Aapro MS et al.: Practical guidance for the management of aromatase inhibitor-associated bone loss. Ann. Oncol. 19, 1407-1416 (2008).
    • (2008) Ann. Oncol , vol.19 , pp. 1407-1416
    • Hadji, P.1    Body, J.-J.2    Aapro, M.S.3
  • 41
    • 0344233260 scopus 로고    scopus 로고
    • Meta-ana lysis of vascular and neoplastic events associated with tamoxifen
    • Braithwaite RS, Chlebowski RT, Lau J et al.: Meta-ana lysis of vascular and neoplastic events associated with tamoxifen. J. Gen. Intern. Med. 18, 937-947 (2003).
    • (2003) J. Gen. Intern. Med , vol.18 , pp. 937-947
    • Braithwaite, R.S.1    Chlebowski, R.T.2    Lau, J.3
  • 42
    • 58149269468 scopus 로고    scopus 로고
    • Use of prescription and over-the-counter medications and dietary supplements among older adults in the United States
    • Qato DM, Alexander GC, Conti RM et al.: Use of prescription and over-the-counter medications and dietary supplements among older adults in the United States. JAMA 300, 2867-2878 (2008).
    • (2008) JAMA , vol.300 , pp. 2867-2878
    • Qato, D.M.1    Alexander, G.C.2    Conti, R.M.3
  • 43
    • 33847034287 scopus 로고    scopus 로고
    • The impact of cytochrome P450 2D6 metabolism in women receiving adjuvant tamoxifen
    • Goetz M, Knox S, Suman V et al.: The impact of cytochrome P450 2D6 metabolism in women receiving adjuvant tamoxifen. Breast Cancer Res. Treat. 101, 113-121 (2007).
    • (2007) Breast Cancer Res. Treat , vol.101 , pp. 113-121
    • Goetz, M.1    Knox, S.2    Suman, V.3
  • 44
    • 68349124835 scopus 로고    scopus 로고
    • Impact of the CYP2D6 genotype on the clinical effects of metoprolol: A prospective longitudinal study
    • Rau T, Wuttke H, Michels LM et al.: Impact of the CYP2D6 genotype on the clinical effects of metoprolol: a prospective longitudinal study. Clin. Pharmacol. Ther. (2008).
    • (2008) Clin. Pharmacol. Ther
    • Rau, T.1    Wuttke, H.2    Michels, L.M.3
  • 45
    • 40549089935 scopus 로고    scopus 로고
    • Influence of the CYP2D6*4 polymorphism on dose, switching and discontinuation of antidepressants
    • Bijl MJ, Visser LE, Hofman A et al.: Influence of the CYP2D6*4 polymorphism on dose, switching and discontinuation of antidepressants. Br. J. Clin. Pharmacol. 65, 558-564 (2008).
    • (2008) Br. J. Clin. Pharmacol , vol.65 , pp. 558-564
    • Bijl, M.J.1    Visser, L.E.2    Hofman, A.3
  • 46
    • 0346602691 scopus 로고    scopus 로고
    • Active tamoxifen metabolite plasma concentrations after coadministration of tamoxifen and the selective serotonin reuptake inhibitor paroxetine
    • Stearns V, Johnson MD, Rae JM et al.: Active tamoxifen metabolite plasma concentrations after coadministration of tamoxifen and the selective serotonin reuptake inhibitor paroxetine. J. Natl Cancer Inst. 95, 1758-1764 (2003).
    • (2003) J. Natl Cancer Inst , vol.95 , pp. 1758-1764
    • Stearns, V.1    Johnson, M.D.2    Rae, J.M.3
  • 47
    • 0034607235 scopus 로고    scopus 로고
    • Tumor characteristics and clinical outcome of elderly women with breast cancer
    • Diab SG, Elledge RM, Clark GM: Tumor characteristics and clinical outcome of elderly women with breast cancer. J. Natl Cancer Inst. 92, 550-556 (2000)
    • (2000) J. Natl Cancer Inst , vol.92 , pp. 550-556
    • Diab, S.G.1    Elledge, R.M.2    Clark, G.M.3
  • 48
    • 0024337144 scopus 로고
    • Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer
    • Slamon DJ, Godolphin W, Jones LA et al.: Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer. Science 244, 707-712 (1989).
    • (1989) Science , vol.244 , pp. 707-712
    • Slamon, D.J.1    Godolphin, W.2    Jones, L.A.3
  • 49
    • 26844503270 scopus 로고    scopus 로고
    • Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer
    • Piccart-Gebhart MJ, Procter M, Leyland-Jones B et al.: Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer. N. Engl. J. Med. 353, 1659-1672 (2005).
    • (2005) N. Engl. J. Med , vol.353 , pp. 1659-1672
    • Piccart-Gebhart, M.J.1    Procter, M.2    Leyland-Jones, B.3
  • 50
    • 26844536978 scopus 로고    scopus 로고
    • Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer
    • Romond EH, Perez EA, Bryant J et al.: Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer. N. Engl. J. Med. 353, 1673-1684 (2005).
    • (2005) N. Engl. J. Med , vol.353 , pp. 1673-1684
    • Romond, E.H.1    Perez, E.A.2    Bryant, J.3
  • 51
    • 33947317453 scopus 로고    scopus 로고
    • BCIRG 006: 2nd interim ana lysis Phase III randomized trial comparing doxorubicin and cyclophosphamide followed by docetaxel (ACT) with doxorubicin and cyclophosphamide followed by docetaxel and trastuzumab (ACTH) with docetaxel, carboplatin and trastuzumab (TCH) in HER2neu positive early breast cancer patients
    • Slamon D, Eiermann W, Robert N et al.: BCIRG 006: 2nd interim ana lysis Phase III randomized trial comparing doxorubicin and cyclophosphamide followed by docetaxel (ACT) with doxorubicin and cyclophosphamide followed by docetaxel and trastuzumab (ACTH) with docetaxel, carboplatin and trastuzumab (TCH) in HER2neu positive early breast cancer patients. Breast. Cancer Res. Treat. (2007).
    • (2007) Breast. Cancer Res. Treat
    • Slamon, D.1    Eiermann, W.2    Robert, N.3
  • 52
    • 29744442709 scopus 로고    scopus 로고
    • Assessment of cardiac dysfunction in a randomized trial comparing doxorubicin and cyclophosphamide followed by paclitaxel, with or without trastuzumab as adjuvant therapy in node-positive, human epidermal growth factor receptor 2-overexpressing breast cancer: NSABP B-31
    • Tan-Chiu E, Yothers G, Romond E et al.: Assessment of cardiac dysfunction in a randomized trial comparing doxorubicin and cyclophosphamide followed by paclitaxel, with or without trastuzumab as adjuvant therapy in node-positive, human epidermal growth factor receptor 2-overexpressing breast cancer: NSABP B-31. J. Clin. Oncol. 23, 7811-7819 (2005).
    • (2005) J. Clin. Oncol , vol.23 , pp. 7811-7819
    • Tan-Chiu, E.1    Yothers, G.2    Romond, E.3
  • 53
    • 41649083764 scopus 로고    scopus 로고
    • Cardiac safety ana lysis of doxorubicin and cyclophosphamide followed by paclitaxel with or without trastuzumab in the north central cancer treatment group N9831 adjuvant breast cancer trial
    • Perez EA, Suman VJ, Davidson NE et al.: Cardiac safety ana lysis of doxorubicin and cyclophosphamide followed by paclitaxel with or without trastuzumab in the north central cancer treatment group N9831 adjuvant breast cancer trial. J. Clin. Oncol. 26, 1231-1238 (2008).
    • (2008) J. Clin. Oncol , vol.26 , pp. 1231-1238
    • Perez, E.A.1    Suman, V.J.2    Davidson, N.E.3
  • 54
    • 33344478381 scopus 로고    scopus 로고
    • Adjuvant docetaxel or vinorelbine with or without trastuzumab for breast cancer
    • Joensuu H, Kellokumpu-Lehtinen P-L, Bono P et al.: Adjuvant docetaxel or vinorelbine with or without trastuzumab for breast cancer. N. Engl. J. Med. 354, 809-820 (2006).
    • (2006) N. Engl. J. Med , vol.354 , pp. 809-820
    • Joensuu, H.1    Kellokumpu-Lehtinen, P.-L.2    Bono, P.3
  • 55
    • 15344348513 scopus 로고    scopus 로고
    • Bone mass density and risk of breast cancer and survival in older women
    • Ganry O, Baudoin C, Fardellone P et al.: Bone mass density and risk of breast cancer and survival in older women. Eur. J. Epidemiol. 19, 785-792 (2004).
    • (2004) Eur. J. Epidemiol , vol.19 , pp. 785-792
    • Ganry, O.1    Baudoin, C.2    Fardellone, P.3
  • 56
    • 33745686577 scopus 로고    scopus 로고
    • Breast cancer and bone mass in older women: Is bone density prescreening for mammography useful?
    • Kritz-Silverstein D, Schneider D, Sandwell J: Breast cancer and bone mass in older women: is bone density prescreening for mammography useful? Osteoporos. Int. 17, 1196-1201 (2006).
    • (2006) Osteoporos. Int , vol.17 , pp. 1196-1201
    • Kritz-Silverstein, D.1    Schneider, D.2    Sandwell, J.3
  • 57
    • 14544279815 scopus 로고    scopus 로고
    • Are breast density and bone mineral density independent risk factors for breast cancer?
    • Kerlikowske K, Shepherd J, Creasman J et al.: Are breast density and bone mineral density independent risk factors for breast cancer? J. Natl Cancer Inst. 97, 368-374 (2005).
    • (2005) J. Natl Cancer Inst , vol.97 , pp. 368-374
    • Kerlikowske, K.1    Shepherd, J.2    Creasman, J.3
  • 58
    • 49949089680 scopus 로고    scopus 로고
    • Adjuvant ovarian suppression combined with tamoxifen or anastrozole, alone or in combination with zoledronic acid, in premenopausal women with hormone-responsive, stage I and II breast cancer: First efficacy results from ABCSG-12
    • Gnant M, Mlineritsch B, Schippinger W et al.: Adjuvant ovarian suppression combined with tamoxifen or anastrozole, alone or in combination with zoledronic acid, in premenopausal women with hormone-responsive, stage I and II breast cancer: first efficacy results from ABCSG-12. J. Clin. Oncol. 26 (2008).
    • (2008) J. Clin. Oncol , vol.26
    • Gnant, M.1    Mlineritsch, B.2    Schippinger, W.3
  • 59
    • 19944422061 scopus 로고    scopus 로고
    • A multigene assay to predict recurrence of tamoxifen-treated, node-negative breast cancer
    • Paik S, Shak S, Tang G et al.: A multigene assay to predict recurrence of tamoxifen-treated, node-negative breast cancer. N. Engl. J. Med. 351, 2817-2826 (2004).
    • (2004) N. Engl. J. Med , vol.351 , pp. 2817-2826
    • Paik, S.1    Shak, S.2    Tang, G.3
  • 60
    • 40449114164 scopus 로고    scopus 로고
    • Prognostic and predictive value of the 21-gene recurrence score assay in postmenopausal, node-positive, ER-positive breast cancer (S8814,INT0100)
    • Albain K, Barlow W, Shak S et al.: Prognostic and predictive value of the 21-gene recurrence score assay in postmenopausal, node-positive, ER-positive breast cancer (S8814,INT0100). Breast. Cancer Res. Treat. (2008).
    • (2008) Breast. Cancer Res. Treat
    • Albain, K.1    Barlow, W.2    Shak, S.3
  • 61
    • 58249087699 scopus 로고    scopus 로고
    • Sensitivity to input variability of the Adjuvant! Online breast cancer prognostic model
    • Ozanne EM, Braithwaite D, Sepucha K et al.: Sensitivity to input variability of the Adjuvant! Online breast cancer prognostic model. J. Clin. Oncol. 27, 214-219 (2009).
    • (2009) J. Clin. Oncol , vol.27 , pp. 214-219
    • Ozanne, E.M.1    Braithwaite, D.2    Sepucha, K.3
  • 62
    • 42949108170 scopus 로고    scopus 로고
    • Efficacy, toxicity, and quality of life in older women with early-stage breast cancer treated with letrozole or placebo after 5 years of tamoxifen: NCIC CTG intergroup trial MA.17
    • Muss HB, Tu D, Ingle JN et al.: Efficacy, toxicity, and quality of life in older women with early-stage breast cancer treated with letrozole or placebo after 5 years of tamoxifen: NCIC CTG intergroup trial MA.17. J. Clin. Oncol. 26, 1956-1964 (2008).
    • (2008) J. Clin. Oncol , vol.26 , pp. 1956-1964
    • Muss, H.B.1    Tu, D.2    Ingle, J.N.3
  • 63
    • 36549075573 scopus 로고    scopus 로고
    • Management of breast cancer in elderly individuals: Recommendations of the international society of geriatric oncology
    • Wildiers H, Kunkler I, Biganzoli L et al.: Management of breast cancer in elderly individuals: recommendations of the international society of geriatric oncology. Lancet Onco. 8, 1101-1115 (2007).
    • (2007) Lancet Onco , vol.8 , pp. 1101-1115
    • Wildiers, H.1    Kunkler, I.2    Biganzoli, L.3
  • 64
  • 65
    • 33947425240 scopus 로고    scopus 로고
    • Effect of undertreatment on the disparity in age-related breast cancer-specific survival among older women
    • Owusu C, Lash T, Silliman R: Effect of undertreatment on the disparity in age-related breast cancer-specific survival among older women. Breast Cancer Res. Treat. 102, 227-236 (2007).
    • (2007) Breast Cancer Res. Treat , vol.102 , pp. 227-236
    • Owusu, C.1    Lash, T.2    Silliman, R.3
  • 66
    • 27244441470 scopus 로고    scopus 로고
    • Developing a cancer-specific geriatric assessment
    • Hurria A, Gupta S, Zauderer M et al.: Developing a cancer-specific geriatric assessment. Cancer 104, 1998-2005 (2005).
    • (2005) Cancer , vol.104 , pp. 1998-2005
    • Hurria, A.1    Gupta, S.2    Zauderer, M.3
  • 67
    • 68349127949 scopus 로고    scopus 로고
    • Does multidimensional geriatric assessment influence the prescription of adjuvant chemotherapy to elderly women with early breast cancer in a multivariate model?
    • Basso U, Bassi C, Falci C et al.: Does multidimensional geriatric assessment influence the prescription of adjuvant chemotherapy to elderly women with early breast cancer in a multivariate model? J. Clin. Oncol. 26 (2008).
    • (2008) J. Clin. Oncol , vol.26
    • Basso, U.1    Bassi, C.2    Falci, C.3
  • 68
    • 34249826935 scopus 로고    scopus 로고
    • Adjuvant therapy in the elderly: Making the right decision
    • Muss HB, Biganzoli L, Sargent DJ et al.: Adjuvant therapy in the elderly: making the right decision. J. Clin. Oncol. 25, 1870-1875 (2007).
    • (2007) J. Clin. Oncol , vol.25 , pp. 1870-1875
    • Muss, H.B.1    Biganzoli, L.2    Sargent, D.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.