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67651158370
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Raritan, NJ: Ortho-McNeil Pharmaceutical, Inc
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Doribax [package insert]. Raritan, NJ: Ortho-McNeil Pharmaceutical, Inc; 2007.
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Doribax [Package Insert]
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2
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60449094372
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press release. Raritan, NJ: June 6, Accessed September 21, 2007
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New drug application submitted for investigational antibiotic doripenem [press release]. Raritan, NJ: Johnson & Johnson; June 6, 2007. http://www.jnj.com/news/jnj-news/20070606-121447.htm. Accessed September 21, 2007.
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New Drug Application Submitted for Investigational Antibiotic Doripenem
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3
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67651175449
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press release. Raritan, NJ: December 15, Accessed September 21, 2007
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New drug application submitted for investigational antibiotic doripenem [press release]. Raritan, NJ: Johnson & Johnson; December 15, 2006. http://www.jnj.com/news/jnj-news/20061215-103306.htm. Accessed September 21, 2007.
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(2006)
New Drug Application Submitted for Investigational Antibiotic Doripenem
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4
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67651155347
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Whitehouse Station, NJ: Merck & Co, Inc
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Primaxin IV [package insert]. Whitehouse Station, NJ: Merck & Co, Inc; 2006.
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Primaxin IV [Package Insert]
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5
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67651180149
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Whitehouse Station, NJ: Merck & Co, Inc
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Primaxin IM [package insert]. Whitehouse Station, NJ: Merck & Co, Inc; 2005.
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Primaxin IM [Package Insert]
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67651147526
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Wilmington, DE: AstraZeneca
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Merrem [package insert]. Wilmington, DE: AstraZeneca; 2007.
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Merrem [Package Insert]
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7
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67651172365
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Whitehouse Station, NJ: Merck & Co, Inc
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Invanz [package insert]. Whitehouse Station, NJ: Merck & Co, Inc; 2007.
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Invanz [Package Insert]
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3543061704
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Doripenem (S-4661), a novel carbapenem: Comparative activity against contemporary pathogens including bactericidal action and preliminary in vitro methods evaluations
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Jones RN, Huynh HK, Beidenbach DJ, Fristche TR, Sader HS. Doripenem (S-4661), a novel carbapenem: comparative activity against contemporary pathogens including bactericidal action and preliminary in vitro methods evaluations. J Antimicrob Chemo. 2004;54(1):144-154.
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Jones, R.N.1
Huynh, H.K.2
Beidenbach, D.J.3
Fristche, T.R.4
Sader, H.S.5
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9
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0033804883
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Comparative pharmacokinetics of the carbapenems: Clinical implications
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Mouton JW, Touzw DJ, Horrevorts AM, Vinks AA. Comparative pharmacokinetics of the carbapenems: clinical implications. Clin Pharmacokinet. 2000;39(3):185-201. (Pubitemid 30727388)
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Clinical Pharmacokinetics
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Mouton, J.W.1
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10
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34248334196
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Comparative review of the carbapenems
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Zhanel GG, Wiebe R, Dilay L, et al. Comparative review of the carbapenems. Drugs. 2007;67(7):1027-1052.
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Drugs
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Zhanel, G.G.1
Wiebe, R.2
Dilay, L.3
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11
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28644447594
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Antimicrobial activity of doripenem (S-4661): A global surveillance report (2003)
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Fritsche TR, Stilwell MG, Jones RN. Antimicrobial activity of doripenem (S-4661): a global surveillance report (2003). Clin Microbiol Infect. 2005;11(12):974-984.
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Clin Microbiol Infect
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Fritsche, T.R.1
Stilwell, M.G.2
Jones, R.N.3
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12
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25844474742
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In vitro activities of doripenem and comparator agents against 364 anaerobic clinical isolates
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DOI 10.1128/AAC.49.10.4413-4417.2005
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Wexler HM, Engel AE, Glass D, Li C. In vitro activities of doripenem and comparator agents against 364 anaerobic clinical isolates. Antimicrob Agents Chemother. 2005;49(10):4413-4417. (Pubitemid 41401003)
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Antimicrobial Agents and Chemotherapy
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Wexler, H.M.1
Engel, A.E.2
Glass, D.3
Li, C.4
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13
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19544371927
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In vitro activity of doripenem (S-4661) against multidrug-resistant gram-negative bacilli isolated from patients with cystic fibrosis
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DOI 10.1128/AAC.49.6.2510-2511.2005
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Chen Y, Garber E, Zhao Q, et al. In vitro activity of doripenem (S-4661) against multidrug-resistant gram-negative bacilli isolated from patients with cystic fibrosis. Antimicrob Agents Chemother. 2005;49(6):2510-2511. (Pubitemid 40734491)
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Antimicrobial Agents and Chemotherapy
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Chen, Y.1
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Zhao, Q.3
Ge, Y.4
Wikler, M.A.5
Kaniga, K.6
Saiman, L.7
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14
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33745278218
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Delayed resistance selection for doripenem when passaging Pseudomonas aeruginosa isolates with doripenem plus an aminoglycoside
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Huynh HK, Beidenbach DJ, Jones RN. Delayed resistance selection for doripenem when passaging Pseudomonas aeruginosa isolates with doripenem plus an aminoglycoside. Diagn Microbiol Infect Dis. 2006;55(3):241-243.
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Diagn Microbiol Infect Dis
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Huynh, H.K.1
Beidenbach, D.J.2
Jones, R.N.3
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15
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67651150662
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Population pharmacokinetics (PPK) of doripenem (DOR) [poster]. Poster A-18
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Van Wart S, Bhavnani SM, Phillips L, Wikler MA, Ambrose PG. Population pharmacokinetics (PPK) of doripenem (DOR) [poster]. 44th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy; October 20-November 2, 2004; Washington, DC. Poster A-18.
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44th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy; October 20-November 2, 2004; Washington, DC
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Van Wart, S.1
Bhavnani, S.M.2
Phillips, L.3
Wikler, M.A.4
Ambrose, P.G.5
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16
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67651158369
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A phase I open-label controlled study to evaluate the safety, tolerability, and pharmacokinetics (PK) of doripenem (DOR) administered intravenously to subjects with renal impairment
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Poster A-17
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Floren L, Wikler M, Kilfoil T, Ge Y. A phase I open-label controlled study to evaluate the safety, tolerability, and pharmacokinetics (PK) of doripenem (DOR) administered intravenously to subjects with renal impairment. 44th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy; October 20-November 2, 2004; Washington, DC. Poster A-17.
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44th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy; October 20-November 2, 2004; Washington, DC
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Floren, L.1
Wikler, M.2
Kilfoil, T.3
Ge, Y.4
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17
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67651158363
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A phase I, double-blind, placebo-controlled study to determine the safety, tolerability, and pharmacokinetics (PK) of prolonged-infusion regimens of doripenem (DOR) in healthy subjects
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abstract. Abstract A-16
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Floren L, Wikler M, Kilfoil T, Ge Y. A phase I, double-blind, placebo-controlled study to determine the safety, tolerability, and pharmacokinetics (PK) of prolonged-infusion regimens of doripenem (DOR) in healthy subjects [abstract]. 44th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy: October 20-November 2, 2004: Washington, DC. Abstract A-16.
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44th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy: October 20-November 2, 2004: Washington, DC
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Floren, L.1
Wikler, M.2
Kilfoil, T.3
Ge, Y.4
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19
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67651155348
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Doripenem vs. meropenem with an option for oral step-down therapy in the treatment of complicated intra-abdominal infections
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abstract. Abstract L-487
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Solomkin JS, Umeh O, Jiang J, Kaniga K, Friedland I. Doripenem vs. meropenem with an option for oral step-down therapy in the treatment of complicated intra-abdominal infections [abstract]. 47th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy; September 17-20, 2007; Chicago, IL. Abstract L-487.
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47th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy; September 17-20, 2007; Chicago, IL
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Solomkin, J.S.1
Umeh, O.2
Jiang, J.3
Kaniga, K.4
Friedland, I.5
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20
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67651173904
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Efficacy and safety of intravenous doripenem vs. piperacillin/tazobactam in nosocomial pneumonia
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abstract. Abstract L-731
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Rea-Neto A, Neiderman M, Prokocimer P, et al. Efficacy and safety of intravenous doripenem vs. piperacillin/tazobactam in nosocomial pneumonia [abstract]. 47th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy; September 17-20, 2007; Chicago, IL. Abstract L-731.
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47th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy; September 17-20, 2007; Chicago, IL
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Rea-Neto, A.1
Neiderman, M.2
Prokocimer, P.3
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21
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67651158371
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Efficacy of doripenem versus imipenem in patients with ventilator-associated pneumonia and high disease severity
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Abstract 1081
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Clavel M, Prokocimer P, Lee M, et al. Efficacy of doripenem versus imipenem in patients with ventilator-associated pneumonia and high disease severity. 45th Annual Infectious Disease Society of America Meeting; October 4-7, 2007; San Diego, CA. Abstract 1081.
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45th Annual Infectious Disease Society of America Meeting; October 4-7, 2007; San Diego, CA
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Clavel, M.1
Prokocimer, P.2
Lee, M.3
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22
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67651152182
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Efficacy and safety of doripenem vs. imipenem for ventilator-associated pneumonia
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abstract. Abstract L-486
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Chastre J, Wunderink R, Prokocimer P, Lee M, Kaniga K, Friedland I. Efficacy and safety of doripenem vs. imipenem for ventilator-associated pneumonia [abstract]. 47th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy; September 17-20, 2007; Chicago, IL. Abstract L-486.
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47th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy; September 17-20, 2007; Chicago, IL
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Chastre, J.1
Wunderink, R.2
Prokocimer, P.3
Lee, M.4
Kaniga, K.5
Friedland, I.6
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23
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33744989013
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Absence of convulsive liability of doripenem, a new carbapenem antibiotic, in comparison with β-lactam antibiotics
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DOI 10.1016/j.tox.2006.02.004, PII S0300483X06001004
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Horiuchi M, Kimura M, Tokumura M, Hasebe N, Arai T, Abe K. Absence of convulsive liability of doripenem, a new carbapenem antibiotic, in comparison with beta-lactam antibiotics. Toxicology. 2006;222(1-2):114-124. (Pubitemid 44275125)
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Toxicology
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Horiuchi, M.1
Kimura, M.2
Tokumura, M.3
Hasebe, N.4
Arai, T.5
Abe, K.6
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24
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9444241653
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Mechanism of the drug interaction between valproic acid and carbapenem antibiotics in monkeys and rats
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DOI 10.1124/dmd.104.000661
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Nakajima Y, Mizobuchi M, Nakamura M, et al. Mechanism of the drug interaction between valproic acid and carbapenem antibiotics in monkeys and rats. Drug Metab Dispos. 2004;32(12):1383-1391. (Pubitemid 39564558)
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Drug Metabolism and Disposition
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Nakajima, Y.1
Mizobuchi, M.2
Nakamura, M.3
Takagi, H.4
Inagaki, H.5
Kominami, G.6
Koike, M.7
Yamaguchi, T.8
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