메뉴 건너뛰기




Volumn 50, Issue 1, 2009, Pages 143-154

Bile salt-phospholipid conjugate ursodeoxycholyl lysophosphatidylethanolamide as a hepatoprotective agent

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOGEN SYNTHASE KINASE 3; LIVER PROTECTIVE AGENT; PHOSPHATIDYLETHANOLAMINE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; UNCLASSIFIED DRUG; URSODEOXYCHOLYL 6 [(7 NITRO 2,1,3 BENZOXADIAZOL 4 YL)AMINO]HEXANOYLPHOSPHATIDYLETHANOLAMINE; URSODEOXYCHOLYLLYSOPHOSPHATIDYLETHANOLAMIDE; BILE ACID; LYSOPHOSPHATIDYLETHANOLAMINE; LYSOPHOSPHOLIPID; PHOSPHOLIPID; URSODEOXYCHOLIC ACID;

EID: 67651148521     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1002/hep.22955     Document Type: Article
Times cited : (43)

References (37)
  • 1
    • 0032771475 scopus 로고    scopus 로고
    • Non-alcoholic fatty liver disease
    • Diehl AM. Non-alcoholic fatty liver disease. Semin Liver Dis 1999;19: 221-1219
    • (1999) Semin Liver Dis , vol.19 , pp. 221-1219
    • Diehl, A.M.1
  • 2
    • 33646121972 scopus 로고    scopus 로고
    • The ratio of phosphatidylcholine to phosphatidylethanolamine influences membrane integrity and steatohepatitis
    • Li Z, Agellon LB, Allen TM, Umeda M, Jewell L, Mason A, et al. The ratio of phosphatidylcholine to phosphatidylethanolamine influences membrane integrity and steatohepatitis. Cell Metab 2006;3:321-331.
    • (2006) Cell Metab , vol.3 , pp. 321-331
    • Li, Z.1    Agellon, L.B.2    Allen, T.M.3    Umeda, M.4    Jewell, L.5    Mason, A.6
  • 3
    • 33845676630 scopus 로고    scopus 로고
    • Betaine attenuates alcoholic steatosis by restoring phosphatidylcholine generation via the phosphatidylethanolamine methyltransferase pathway
    • DOI 10.1016/j.jhep.2006.08.024, PII S0168827806005460
    • Kharbanda K, Mailliard ME, Baldwin CR, Beckenhauer HC, Sorrell MF, Tuma DJ. Betaine attenuates alcoholic steatosis by restoring phosphatidylcholine generation via the phosphatidylethanolamine methyltransferase pathway. J Hepatol 2007;46:314-321. (Pubitemid 44959154)
    • (2007) Journal of Hepatology , vol.46 , Issue.2 , pp. 314-321
    • Kharbanda, K.K.1    Mailliard, M.E.2    Baldwin, C.R.3    Beckenhauer, H.C.4    Sorrell, M.F.5    Tuma, D.J.6
  • 6
    • 36348969601 scopus 로고    scopus 로고
    • Hepatic phosphatidylethanolamine N-methyltransferase, unexpected roles in animal biochemistry and physiology
    • DOI 10.1074/jbc.R700028200
    • Vance DE, Zhaoyu L, Jacobs R. Hepatic phosphatidylethanolamine N-methyltransferase, unexpected roles in animal biochemistry and physiology. J Biol Chem 2008;282:33237-33241. (Pubitemid 350159494)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.46 , pp. 33237-33241
    • Vance, D.E.1    Li, Z.2    Jacobs, R.L.3
  • 7
    • 12844288099 scopus 로고    scopus 로고
    • Alcoholic fatty liver: Its pathogenesis and mechanism of progression to inflammation and fibrosis
    • Lieber CS. Alcoholic fatty liver: its pathogenesis and mechanism of progression to inflammation and fibrosis. Alcohol 2004;34:9-19.
    • (2004) Alcohol , vol.34 , pp. 9-19
    • Lieber, C.S.1
  • 8
    • 0345256577 scopus 로고    scopus 로고
    • II. Veterans Affairs Cooperative Study of polyenylphosphatidylcholine in alcoholic liver disease
    • For the Veterans Affairs Cooperative Study 391 Group
    • Lieber CS, Weiss DG, Groszmann R, Paronetto F, Schenker S; For the Veterans Affairs Cooperative Study 391 Group. II. Veterans Affairs Cooperative Study of polyenylphosphatidylcholine in alcoholic liver disease. Alcohol Clin Exp Res 2003;27:1765-1772.
    • (2003) Alcohol Clin Exp Res , vol.27 , pp. 1765-1772
    • Lieber, C.S.1    Weiss, D.G.2    Groszmann, R.3    Paronetto, F.4    Schenker, S.5
  • 9
    • 0034834208 scopus 로고    scopus 로고
    • Betaine, a promising new agent for patients with nonalcoholic steatohepatitis: Results of a pilot study
    • DOI 10.1016/S0002-9270(01)02691-0, PII S0002927001026910
    • Abdelmalek MF, Angulo P, Jorgensen RA, Sylvestre PB, Lindor KD. Betaine, a promising new agent for patients with nonalcoholic steatohepatitis: results of a pilot study. Am J Gastroenterol 2001;96:2711-2717. (Pubitemid 32889210)
    • (2001) American Journal of Gastroenterology , vol.96 , Issue.9 SUPPL. , pp. 2711-2717
    • Abdelmalek, M.F.1    Angulo, P.2    Jorgensen, R.A.3    Sylvestre, P.B.4    Lindor, K.D.5
  • 10
    • 21044457089 scopus 로고    scopus 로고
    • Retarded release phosphatidylcholine benefits patients with chronic active ulcerative colitis
    • DOI 10.1136/gut.2004.052316
    • Stremmel W, Merle U, Zahn A, Autschbach F, Hinz U, Ehehalt R. Retarded release phosphatidylcholine benefits patients with chronic active ulcerative colitis. Gut 2005;54:966-971. (Pubitemid 40873911)
    • (2005) Gut , vol.54 , Issue.7 , pp. 966-971
    • Stremmel, W.1    Merle, U.2    Zahn, A.3    Autschbach, F.4    Hinz, U.5    Ehehalt, R.6
  • 15
    • 0032525819 scopus 로고    scopus 로고
    • A novel role for ursodeoxycholic acid in inhibiting apoptosis by modulating mitochondrial membrane perturbation
    • Rodrigues CM, Fan G, Ma X, Kren BT, Steer CJ. A novel role for ursodeoxycholic acid in inhibiting apoptosis by modulating mitochondrial membrane perturbation. J Clin Invest 1998;101:2790-2799. (Pubitemid 28294588)
    • (1998) Journal of Clinical Investigation , vol.101 , Issue.12 , pp. 2790-2799
    • Rodrigues, C.M.P.1    Fan, G.2    Ma, X.3    Kren, B.T.4    Steer, C.J.5
  • 16
    • 0021338864 scopus 로고
    • Uptake and metabolism of polyene phosphatidylcholine in rat brain
    • Lekim D, Betzing H. Uptake and metabolism of polyene phosphatidylcholine in rat brain. Arzneimittelforschungs 1984;34:557-559. (Pubitemid 14145544)
    • (1984) Arzneimittel-Forschung/Drug Research , vol.34 , Issue.5 , pp. 557-559
    • Lekim, D.1    Betzing, H.2
  • 17
    • 38549170406 scopus 로고    scopus 로고
    • Encapsulated fat necrosis after lipolysis of the calf with phosphatidylcholine [1]
    • DOI 10.1159/000111519
    • Bechara FG, Georgas D, Sand M, Tomi N, Altmeyer P, Hoffmann K. Encapsulated fat necrosis after lipolysis of the calf with phosphatidylcholine. Dermatology 2008;216:180-181. (Pubitemid 351158587)
    • (2008) Dermatology , vol.216 , Issue.2 , pp. 180-181
    • Bechara, F.G.1    Georgas, D.2    Sand, M.3    Tomi, N.4    Altmeyer, P.5    Hoffmann, K.6
  • 18
    • 0141839070 scopus 로고    scopus 로고
    • Increased plasma homocysteine and S-adenosylhomocysteine and decreased methionine is associated with altered phosphatidylcholine and phosphatidylethanolamine in cystic fibrosis
    • DOI 10.1067/S0022-3476(03)00326-3
    • Innis SM, Davidson AG, Chen A, Dyer R, Melnyk S, James SJ. Increased plasma homocysteine and S-adenosylhomocysteine and decreased methionine is associated with altered phosphatidylcholine and phosphatidylethanolamine in cystic fibrosis. J Pediatr 2003;143:351-356. (Pubitemid 37188320)
    • (2003) Journal of Pediatrics , vol.143 , Issue.3 , pp. 351-356
    • Innis, S.M.1    Davidson, A.G.F.2    Chen, A.3    Dyer, R.4    Melnyk, S.5    James, S.J.6
  • 19
    • 0034705619 scopus 로고    scopus 로고
    • Overexpression of catalase in the mitochondrial or cytosolic compartment increases sensitivity of HepG2 cells to tumor necrosis factor-alpha-induced apoptosis
    • Bai J, Cederbaum AI. Overexpression of catalase in the mitochondrial or cytosolic compartment increases sensitivity of HepG2 cells to tumor necrosis factor-alpha-induced apoptosis. J Biol Chem 2000;275:19241-19249.
    • (2000) J Biol Chem , vol.275 , pp. 19241-19249
    • Bai, J.1    Cederbaum, A.I.2
  • 20
    • 0029870313 scopus 로고    scopus 로고
    • Molecular and functional characterization of bile acid transport in human hepatoblastoma HepG2 cells
    • DOI 10.1053/jhep.1996.v23.pm0008621133
    • Kullak-Ublick GA, Beuers U, Paumgartner G. Molecular and functional characterization of bile acid transport in human hepatoblastoma HepG2 cells. HEPATOLOGY 1996;23:1053-1060. (Pubitemid 26137046)
    • (1996) Hepatology , vol.23 , Issue.5 , pp. 1053-1060
    • Kullak-Ublick, G.-A.1    Beuers, U.2    Paumgartner, G.3
  • 21
    • 0021099286 scopus 로고
    • Biosynthesis of phosphatidylcholine from serum phospholipids in Chinese hamster ovary cells deprived of choline
    • Esko JD, Matsuoka KY. Biosynthesis of phosphatidylcholine from serum phospholipids in Chinese hamster ovary cells deprived of choline. J Biol Chem 1983;258:3051-3057.
    • (1983) J Biol Chem , vol.258 , pp. 3051-3057
    • Esko, J.D.1    Matsuoka, K.Y.2
  • 22
    • 0035658526 scopus 로고    scopus 로고
    • Enhancement of survival by LPA via Erk1/Erk2 and PI 3-kinase/Akt pathways in a murine hepatocyte cell line
    • Sautin YY, Crawford JM, Svetlov SI. Enhancement of survival by LPA via Erk1/Erk2 and PI3-kinase/Akt pathways in a murine hepatocyte cell line. Am J Physiol Cell Physiol 2001;281:C2010-C2019. (Pubitemid 33775047)
    • (2001) American Journal of Physiology , vol.281 , Issue.6 PART 1
    • Sautin, Y.Y.1    Crawford, J.M.2    Svetlov, S.I.3
  • 23
    • 0036211298 scopus 로고    scopus 로고
    • Inhibition of the MAPK and PI3K pathways enhances UDCA-induced apoptosis in primary rodent hepatocytes
    • DOI 10.1053/jhep.2002.32533
    • Qiao L, Yacoub A, Studer E, Gupta S, Pei XY, Grant S, et al. Inhibition of the MAPK and PI3K pathways enhances UDCA-induced apoptosis in primary rodent hepatocytes. HEPATOLOGY 2002;35:779-789. (Pubitemid 34258371)
    • (2002) Hepatology , vol.35 , Issue.4 , pp. 779-789
    • Qiao, L.1    Yacoub, A.2    Studer, E.3    Gupta, S.4    Pei, X.Y.5    Grant, S.6    Hylemon, P.B.7    Dent, P.8
  • 24
    • 40949163839 scopus 로고    scopus 로고
    • Deoxycholyltaurine rescues human colon cancer cells from apoptosis by activating EGFR-dependent PI3K/Akt signaling
    • Raufman J-P, Shant J, Guo CY, Roy S, Cheng K. Deoxycholyltaurine rescues human colon cancer cells from apoptosis by activating EGFR-dependent PI3K/Akt signaling. J Cell Physiol 2008;215:538-549.
    • (2008) J Cell Physiol , vol.215 , pp. 538-549
    • Raufman, J.-P.1    Shant, J.2    Guo, C.Y.3    Roy, S.4    Cheng, K.5
  • 25
    • 0037203313 scopus 로고    scopus 로고
    • Phosphatidylcholine and cell death
    • Cui Z, Houweling M. Phosphatidylcholine and cell death. Biochim Biophys Acta 2002;1585:87-96.
    • (2002) Biochim Biophys Acta , vol.1585 , pp. 87-96
    • Cui, Z.1    Houweling, M.2
  • 26
    • 0034737659 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha inhibits expression of CTP:phosphocholine cytidylyltransferase
    • DOI 10.1074/jbc.275.13.9699
    • Mallampalli RK, Ryan AJ, Salome RG, Jackowski S. Tumor necrosis factor- alpha inhibits expression of CTP:phosphocholine cytidylyltransferase. J Biol Chem 2000;275:9699-9708. (Pubitemid 30185203)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.13 , pp. 9699-9708
    • Mallampalli, R.K.1    Ryan, A.J.2    Salome, R.G.3    Jackowski, S.4
  • 29
    • 12544260246 scopus 로고    scopus 로고
    • CTP: Phosphocholine cytidylyltransferase: paving the way from gene to membrane
    • Jackowski S, Fagone P. CTP: phosphocholine cytidylyltransferase: paving the way from gene to membrane. J Biol Chem 2005;280:853-856.
    • (2005) J Biol Chem , vol.280 , pp. 853-856
    • Jackowski, S.1    Fagone, P.2
  • 31
    • 0026545179 scopus 로고
    • Phosphatidylethanolamine metabolism in rat liver after partial hepatectomy. Control of biosynthesis of phosphatidylethanolamine by the availability of ethanolamine
    • Houweling M, Tijburg LB, Vaartjes WJ, van Golde LM. Phosphatidylethanolamine metabolism in rat liver after partial hepatectomy. Control of biosynthesis of phosphatidylethanolamine by the availability of ethanolamine. Biochem J 1992;283:55-61.
    • (1992) Biochem J , vol.283 , pp. 55-61
    • Houweling, M.1    Tijburg, L.B.2    Vaartjes, W.J.3    Van Golde, L.M.4
  • 32
    • 2942661921 scopus 로고    scopus 로고
    • Dimethylethanolamine does not prevent liver failure in phosphatidylethanolamine N-methyltransferase-deficient mice fed a choline-deficient diet
    • Waite KA, Vance DE. Dimethylethanolamine does not prevent liver failure in phosphatidylethanolamine N-methyltransferase-deficient mice fed a choline-deficient diet. Biochim Biophys Acta 2004;1636:175-182.
    • (2004) Biochim Biophys Acta , vol.1636 , pp. 175-182
    • Waite, K.A.1    Vance, D.E.2
  • 33
    • 0343488500 scopus 로고    scopus 로고
    • Ursodeoxycholate stabilizes phospholipid-rich membranes and mimics the effect of cholesterol: Investigations on large unilamellar vesicles
    • DOI 10.1016/S0005-2736(97)00030-8, PII S0005273697000308
    • Güldütuna S, Deisinger B, Weiss A, Freisleben HJ, Zimmer G, Sipos P, et al. Ursodeoxycholate stabilizes phospholipid-rich membranes and mimics the effect of cholesterol: investigations on large unilamellar vesicles. Biochim Biophys Acta 1997;1326:265-274. (Pubitemid 27272131)
    • (1997) Biochimica et Biophysica Acta - Biomembranes , vol.1326 , Issue.2 , pp. 265-274
    • Guldutuna, S.1    Deisinger, B.2    Weiss, A.3    Freisleben, H.-J.4    Zimmer, G.5    Sipos, P.6    Leuschner, U.7
  • 34
    • 0028351832 scopus 로고
    • Ursodeoxycholate conjugates protect against disruption of cholesterol- Rich membranes by bile salts
    • Heuman DM, Bajaj R. Ursodeoxycholate conjugates protect against disruption of cholesterol-rich membranes by bile salts. Gastroenterology 1994;106:1333-1341. (Pubitemid 24129252)
    • (1994) Gastroenterology , vol.106 , Issue.5 , pp. 1333-1341
    • Heuman, D.M.1    Bajaj, R.2
  • 35
    • 0032533225 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localization
    • Diehl JA, Cheng M, Roussel MF, Sherr CJ. Glycogen synthase kinase- 3beta regulates cyclin D1 proteolysis and subcellular localization. Genes Dev 1998;12:3499-3511. (Pubitemid 28553242)
    • (1998) Genes and Development , vol.12 , Issue.22 , pp. 3499-3511
    • Diehl, J.A.1    Cheng, M.2    Roussel, M.F.3    Sherr, C.J.4
  • 36
    • 33847153848 scopus 로고    scopus 로고
    • Matrix metalloproteinase-7-catalyzed release of HB-EGF mediates deoxycholyltaurine-induced proliferation of a human colon cancer cell line
    • DOI 10.1016/j.bcp.2006.11.028, PII S0006295206008069
    • Cheng K, Xie G, Raufman JP. Matrix metalloproteinase-7-catalyzed release of HB-EGF mediates deoxycholyltaurine-induced proliferation of a human colon cancer cell line. Biochem Pharmacol 2007;73:1001-1012. (Pubitemid 46283578)
    • (2007) Biochemical Pharmacology , vol.73 , Issue.7 , pp. 1001-1012
    • Cheng, K.1    Xie, G.2    Raufman, J.-P.3
  • 37
    • 33645151670 scopus 로고    scopus 로고
    • Dexamethasone protects primary cultured hepatocytes from death receptor-mediated apoptosis by upregulation of cFLIP
    • Oh HY, Namkoong S, Lee SJ, Por E, Kim CK, Billiar TR, et al. Dexamethasone protects primary cultured hepatocytes from death receptor-mediated apoptosis by upregulation of cFLIP. Cell Death Differ 2006;13:512-523.
    • (2006) Cell Death Differ , vol.13 , pp. 512-523
    • Oh, H.Y.1    Namkoong, S.2    Lee, S.J.3    Por, E.4    Kim, C.K.5    Billiar, T.R.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.