메뉴 건너뛰기




Volumn 47, Issue SUPPL. 1, 2009, Pages

Essential pathway identification: From in silico analysis to potential antifungal targets in Aspergillus fumigatus

Author keywords

Antifungal; Aspergillus; Computational; Essential genes

Indexed keywords

1,3 BETA GLUCAN SYNTHASE; 3 DEOXY 7 PHOSPHOHEPTULONATE SYNTHASE; ADENOSINE TRIPHOSPHATE PHOSPHORIBOSYLTRANSFERASE; ANTHRANILATE PHOSPHORIBOSYLTRANSFERASE; ASPARTATE KINASE; CHORISMATE MUTASE; FATTY ACID; FATTY ACID SYNTHASE; GLUTAMATE N ACETYLTRANSFERASE; HISTIDINOL DEHYDROGENASE; HISTIDINOL PHOSPHATASE; HOMOSERINE ACETYLTRANSFERASE; HOMOSERINE DEHYDROGENASE; KETOL ACID REDUCTOISOMERASE; MANNITOL; MANNITOL 1 PHOSPHATE 5 DEHYDROGENASE; METHIONINE SYNTHASE; METHYLENE FATTY ACYL PHOSPHOLIPID SYNTHASE; OROTATE PHOSPHORIBOSYLTRANSFERASE; PHOSPHOMEVALONATE KINASE; PHOSPHORIBOSYL AMINOIMIDAZOLE CARBOXYLASE; PREPHENATE DEHYDRATASE; PURINE; PYRIMIDINE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SQUALENE SYNTHASE; STEROL; THIOREDOXIN REDUCTASE; UNCLASSIFIED DRUG; UREA;

EID: 67651115984     PISSN: 13693786     EISSN: 14602709     Source Type: Journal    
DOI: 10.1080/13693780802455305     Document Type: Article
Times cited : (17)

References (27)
  • 1
    • 0033801039 scopus 로고    scopus 로고
    • Practice guidelines for diseases caused by Aspergillus
    • Stevens DA, Kan VL, Judson MA, et al. Practice guidelines for diseases caused by Aspergillus. Clin Infect Dis 2000; 30 696-709.
    • (2000) Clin Infect Dis , vol.30 , pp. 696-709
    • Stevens, D.A.1    Kan, V.L.2    Judson, M.A.3
  • 2
    • 0036253145 scopus 로고    scopus 로고
    • Invasive fungal infections: Evolving challenges for diagnosis and therapeutics
    • Ellis M. Invasive fungal infections: Evolving challenges for diagnosis and therapeutics. Mol Immunol 2002; 38: 947-957.
    • (2002) Mol Immunol , vol.38 , pp. 947-957
    • Ellis, M.1
  • 5
    • 34047236515 scopus 로고    scopus 로고
    • Essential gene identification and drug target prioritization in Aspergillus fumigatus
    • doi:10.1371/ journal.ppat.0030024
    • Hu W, Sillaots S, Lemieux S, Davison J, Kauffman S, et al. (2007). Essential gene identification and drug target prioritization in Aspergillus fumigatus. PLoS Pathog 3(3): E24. doi:10.1371/ journal.ppat.0030024
    • (2007) PLoS Pathog , vol.3 , Issue.3
    • Hu, W.1    Sillaots, S.2    Lemieux, S.3    Davison, J.4    Kauffman, S.5
  • 6
    • 0038058886 scopus 로고    scopus 로고
    • Identification of essential genes in the human fungal pathogen Aspergillus fumigatus by transposon mutagenesis
    • Firon A, Villalba F, Beffa R, d'Enfert C. Identification of essential genes in the human fungal pathogen Aspergillus fumigatus by transposon mutagenesis. Eukary Cell 2003; 2: 247-255.
    • (2003) Eukary Cell , vol.2 , pp. 247-255
    • Firon, A.1    Villalba, F.2    Beffa, R.3    d'Enfert, C.4
  • 7
    • 0033604566 scopus 로고    scopus 로고
    • Large-scale analysis of the yeast genome by transposon tagging and gene disruption
    • Ross-Macdonald P, Coelho PSR, Roemer T, et al. Large-scale analysis of the yeast genome by transposon tagging and gene disruption. Nature 1999; 402: 413-418.
    • (1999) Nature , vol.402 , pp. 413-418
    • Ross-Macdonald, P.1    Coelho, P.S.R.2    Roemer, T.3
  • 8
    • 0035103447 scopus 로고    scopus 로고
    • An antisense-based functional genomics approach for identification of genes critical for growth of Candida albicans
    • De Backer MD, Nelissen B, Logghe M, et al. An antisense-based functional genomics approach for identification of genes critical for growth of Candida albicans. Nature Biotechnol 2001; 19 235-241.
    • (2001) Nature Biotechnol , vol.19 , pp. 235-241
    • De Backer, M.D.1    Nelissen, B.2    Logghe, M.3
  • 9
    • 34548842996 scopus 로고    scopus 로고
    • Identification and analysis of essential Aspergillus nidulans genes using the heterokaryon rescue technique
    • Osmani AH, Oakley BR, Osmani SA. Identification and analysis of essential Aspergillus nidulans genes using the heterokaryon rescue technique. Nature Protocols 2006; 1: 2517-2526.
    • (2006) Nature Protocols , vol.1 , pp. 2517-2526
    • Osmani, A.H.1    Oakley, B.R.2    Osmani, S.A.3
  • 11
    • 31544450286 scopus 로고    scopus 로고
    • Construction of Escherichia coli K-12 in-frame, single-gene knockout mutants: The Keio collection
    • doi:10.1038/msb4100050
    • Baba T, Ara T, Hasegawa M, et al. Construction of Escherichia coli K-12 in-frame, single-gene knockout mutants: The Keio collection. Mol Syst Biol 2006; doi:10.1038/msb4100050.
    • (2006) Mol Syst Biol
    • Baba, T.1    Ara, T.2    Hasegawa, M.3
  • 12
    • 0037173615 scopus 로고    scopus 로고
    • Functional profiling of the Saccharomyces cerevisiae genome
    • Giaever G, Chu AM, Ni L, et al. Functional profiling of the Saccharomyces cerevisiae genome. Nature 2002; 418: 387-391.
    • (2002) Nature , vol.418 , pp. 387-391
    • Giaever, G.1    Chu, A.M.2    Ni, L.3
  • 13
    • 41149105489 scopus 로고    scopus 로고
    • Metabolic model integration of the bibliome, genome, metabolome, and reactome of Aspergillus niger
    • Andersen MR, Nielsen ML, Nielsen J. Metabolic model integration of the bibliome, genome, metabolome, and reactome of Aspergillus niger. Mol Syst Biol 2008; 4: 178.
    • (2008) Mol Syst Biol , vol.4 , pp. 178
    • Andersen, M.R.1    Nielsen, M.L.2    Nielsen, J.3
  • 14
    • 33749519986 scopus 로고    scopus 로고
    • Aspergillus niger genomics: Past, present and into the future
    • Baker SE. Aspergillus niger genomics: Past, present and into the future. Med Mycol 2006; 44: S17-S21.
    • (2006) Med Mycol , vol.44
    • Baker, S.E.1
  • 15
    • 33846861493 scopus 로고    scopus 로고
    • Genome sequencing and analysis of the versatile cell factory Aspergillus niger CBS 513.88
    • Pel HJ, de Winde JH, Archer DB, et al. Genome sequencing and analysis of the versatile cell factory Aspergillus niger CBS 513.88. Nature Biotechnol 2007; 25: 221-231.
    • (2007) Nature Biotechnol , vol.25 , pp. 221-231
    • Pel, H.J.1    de Winde, J.H.2    Archer, D.B.3
  • 16
    • 28644434509 scopus 로고    scopus 로고
    • Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus
    • Nierman WC, Pain A, Anderson MJ, et al. Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus Nature 2005; 438: 1151-1156.
    • (2005) Nature , vol.438 , pp. 1151-1156
    • Nierman, W.C.1    Pain, A.2    Anderson, M.J.3
  • 17
    • 16444381885 scopus 로고    scopus 로고
    • A comprehensive evolutionary classification of proteins encoded in complete eukaryotic genomes
    • Koonin EV, Fedorova ND, Jackson JD, et al. A comprehensive evolutionary classification of proteins encoded in complete eukaryotic genomes. Genome Biol 2004; 5: R7.
    • (2004) Genome Biol , vol.5
    • Koonin, E.V.1    Fedorova, N.D.2    Jackson, J.D.3
  • 18
    • 0022195719 scopus 로고
    • Development of a high-frequency transforming vector for Aspergillus nidulans
    • Ballance DJ, Turner G. Development of a high-frequency transforming vector for Aspergillus nidulans. Gene 1985; 36: 321-331.
    • (1985) Gene , vol.36 , pp. 321-331
    • Ballance, D.J.1    Turner, G.2
  • 19
    • 0023098176 scopus 로고    scopus 로고
    • van Hartingsveldt W, Mattern IE, van Zeijl C, M., Pouwels PH, van den Hondel CA. Development of a homologous transformation system for Aspergillus niger based on the pyrG gene. Mol Gen Genet 1987; 206: 71-75.
    • van Hartingsveldt W, Mattern IE, van Zeijl C, M., Pouwels PH, van den Hondel CA. Development of a homologous transformation system for Aspergillus niger based on the pyrG gene. Mol Gen Genet 1987; 206: 71-75.
  • 20
    • 0024730362 scopus 로고
    • A gene transfer system based on the homologous pyrG gene and efficient expression of bacterial genes in Aspergillus oryzae
    • de Ruiter-Jacobs YM, Broekhuijsen M, Unkles SE, et al. A gene transfer system based on the homologous pyrG gene and efficient expression of bacterial genes in Aspergillus oryzae. Curr Genet 1989; 16: 156-163.
    • (1989) Curr Genet , vol.16 , pp. 156-163
    • de Ruiter-Jacobs, Y.M.1    Broekhuijsen, M.2    Unkles, S.E.3
  • 21
    • 0029028453 scopus 로고    scopus 로고
    • Gouka RJ, Hessing JG, Stam H, MustersW, van den Hondel CA. A novel strategy for the isolation of defined pyrG mutants and the development of a site-specific integration system for Aspergillus awamori. Curr Genet 1995; 27: 536-540.
    • Gouka RJ, Hessing JG, Stam H, MustersW, van den Hondel CA. A novel strategy for the isolation of defined pyrG mutants and the development of a site-specific integration system for Aspergillus awamori. Curr Genet 1995; 27: 536-540.
  • 22
    • 0030018118 scopus 로고    scopus 로고
    • Selection of multiple disruption events in Aspergillus fumigatus using the orotidine-5′-decarboxylase gene, pyrG, as a unique transformation marker
    • D'Enfert C. Selection of multiple disruption events in Aspergillus fumigatus using the orotidine-5′-decarboxylase gene, pyrG, as a unique transformation marker. Cur Genet 1996; 30: 76-82.
    • (1996) Cur Genet , vol.30 , pp. 76-82
    • D'Enfert, C.1
  • 23
    • 0031861605 scopus 로고    scopus 로고
    • Development of a homologous transformation system for the human pathogenic fungus Aspergillus fumigatus based on the pyrG gene encoding orotidine 5′-monophosphate decarboxylase
    • Weidner G, d'Enfert C, Koch A, Mol PC, Brakhage AA. Development of a homologous transformation system for the human pathogenic fungus Aspergillus fumigatus based on the pyrG gene encoding orotidine 5′-monophosphate decarboxylase. Curr Genet 1998; 33: 378-385.
    • (1998) Curr Genet , vol.33 , pp. 378-385
    • Weidner, G.1    d'Enfert, C.2    Koch, A.3    Mol, P.C.4    Brakhage, A.A.5
  • 24
    • 0029797595 scopus 로고    scopus 로고
    • Attenuated virulence of uridine-uracil auxotrophs of Aspergillus fumigatus
    • D'Enfert C, Diaquin M, Delit A, et al. Attenuated virulence of uridine-uracil auxotrophs of Aspergillus fumigatus. Inf Immun 1996; 64: 4401-4405.
    • (1996) Inf Immun , vol.64 , pp. 4401-4405
    • D'Enfert, C.1    Diaquin, M.2    Delit, A.3
  • 25
    • 2442708820 scopus 로고    scopus 로고
    • Deletion of the Aspergillus fumigatus lysine biosynthesis gene lysF encoding homoaconitase leads to attenuated virulence in a low-dose mouse infection model of invasive aspergillosis
    • Liebmann B, Muhleisen TW, Muller M, et al. Deletion of the Aspergillus fumigatus lysine biosynthesis gene lysF encoding homoaconitase leads to attenuated virulence in a low-dose mouse infection model of invasive aspergillosis. Arch Microbiol 2004; 181: 378-383.
    • (2004) Arch Microbiol , vol.181 , pp. 378-383
    • Liebmann, B.1    Muhleisen, T.W.2    Muller, M.3
  • 26
    • 22544450473 scopus 로고    scopus 로고
    • Methylcitrate synthase from Aspergillus fumigatus-Propionyl-CoA affects polyketide synthesis, growth and morphology of conidia
    • Maerker C, Rohde M, Brakhage AA, Brock M. Methylcitrate synthase from Aspergillus fumigatus-Propionyl-CoA affects polyketide synthesis, growth and morphology of conidia. FEBS J 2005; 272: 3615-3630.
    • (2005) FEBS J , vol.272 , pp. 3615-3630
    • Maerker, C.1    Rohde, M.2    Brakhage, A.A.3    Brock, M.4
  • 27
    • 36949031736 scopus 로고    scopus 로고
    • Methylcitrate synthase from Aspergillus fumigatus is essential for manifestation of invasive aspergillosis
    • Ibrahim-Granet O, Dubourdeau M, Latgé JP, et al. Methylcitrate synthase from Aspergillus fumigatus is essential for manifestation of invasive aspergillosis. Cell Microbio 2008; 10: 134-148.
    • (2008) Cell Microbio , vol.10 , pp. 134-148
    • Ibrahim-Granet, O.1    Dubourdeau, M.2    Latgé, J.P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.