Association of genetic polymorphisms in the type II deiodinase gene with bipolar disorder in a subset of Chinese population

Progress in Neuro-Psychopharmacology and Biological Psychiatry

Volumn 33, Issue 6, 2009, Pages 986-990

  He, Bing ^a   Li, Junyan ^b   Wang, Gang ^c   Ju, Weina ^d   Lu, Yadong ^a   Shi, Yongyong ^b   He, Lin ^b   Zhong, Nanbert ^a,d  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^b SHANGHAI JIAO TONG UNIVERSITY   (China)

^c CAPITAL MEDICAL UNIVERSITY   (China)

^d NEW YORK STATE INSTITUTE FOR BASIC RESEARCH IN DEVELOPMENTAL DISABILITIES   (United States)

Author keywords

Bipolar disorder; Case control study; Single nucleotide polymorphism; Type II deiodinase

Indexed keywords

ALANINE; ASPARTIC ACID; GLYCINE; THREONINE; THYROID HORMONE; TYPE II DEIODINASE; UNCLASSIFIED DRUG;

ADULT; ARTICLE; BIPOLAR DISORDER; CASE CONTROL STUDY; CHINESE; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; GENE FREQUENCY; GENE LOCUS; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENOTYPE; HAPLOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; OPEN READING FRAME; POPULATION RESEARCH; PROTEIN FUNCTION; PROTEIN LOCALIZATION; SINGLE NUCLEOTIDE POLYMORPHISM;

ADOLESCENT; ADULT; ALLELES; ASIAN CONTINENTAL ANCESTRY GROUP; BIPOLAR DISORDER; CASE-CONTROL STUDIES; FEMALE; GENETIC VARIATION; GENOTYPE; HUMANS; IODIDE PEROXIDASE; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; YOUNG ADULT;

EID: 67651091543     PISSN: 02785846     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pnpbp.2009.05.003     Document Type: Article

References (48)

1. Adams L.J., Mitchell P.B., Fielder S.L., Rosso A., Donald J.A., and Schofield P.R. A susceptibility locus for bipolar affective disorder on chromosome 4q35. Am J Hum Genet 62 (1998) 1084-1091
2. Badenhop R.F., Moses M.J., Scimone A., Adams L.J., Kwok J.B., Jones A.M., et al. Genetic refinement and physical mapping of a 2.3 Mb probable disease region associated with a bipolar affective disorder susceptibility locus on chromosome 4q35. Am J Med Genet B Neuropsychiatr Genet 117B (2003) 23-32
3. Bahls S.C., and de Carvalho G.A. [The relation between thyroid function and depression: a review]. Rev Bras Psiquiatr 26 (2004) 41-49
4. Baumgartner A., Pinna G., Hiedra L., Gaio U., Hessenius C., Campos-Barros A., et al. Effects of lithium and carbamazepine on thyroid hormone metabolism in rat brain. Neuropsychopharmacology 16 (1997) 25-41
5. Bertelsen A., Harvald B., and Hauge M. A Danish twin study of manic-depressive disorders. Br J Psychiatry 130 (1977) 330-351
6. Blackwood D.H., He L., Morris S.W., McLean A., Whitton C., Thomson M., et al. A locus for bipolar affective disorder on chromosome 4p. Nat Genet 12 (1996) 427-430
7. Canani L.H., Capp C., Dora J.M., Meyer E.L., Wagner M.S., Harney J.W., et al. The type 2 deiodinase A/G (Thr92Ala) polymorphism is associated with decreased enzyme velocity and increased insulin resistance in patients with type 2 diabetes mellitus. J Clin Endocrinol Metab 90 (2005) 3472-3478
8. Collier D.A., Stober G., Li T., Heils A., Catalano M., Di Bella D., et al. A novel functional polymorphism within the promoter of the serotonin transporter gene: possible role in susceptibility to affective disorders. Mol Psychiatry 1 (1996) 453-460
9. Coppotelli G., Summers A., Chidakel A., Ross J.M., and Celi F.S. Functional characterization of the 258 A/G (D2-ORFa-Gly3Asp) human type-2 deiodinase polymorphism: a naturally occurring variant increases the enzymatic activity by removing a putative repressor site in the 5′ UTR of the gene. Thyroid 16 (2006) 625-632
10. Crantz F.R., Silva J.E., and Larsen P.R. An analysis of the sources and quantity of 3,5,3′-triiodothyronine specifically bound to nuclear receptors in rat cerebral cortex and cerebellum. Endocrinology 110 (1982) 367-375
11. Croteau W., Davey J.C., Galton V.A., and St Germain D.L. Cloning of the mammalian type II iodothyronine deiodinase. A selenoprotein differentially expressed and regulated in human and rat brain and other tissues. J Clin Invest 98 (1996) 405-417
12. Cunha A.B., Andreazza A.C., Gomes F.A., Frey B.N., da Silveira L.E., Goncalves C.A., et al. Investigation of serum high-sensitive C-reactive protein levels across all mood states in bipolar disorder. Eur Arch Psychiatry Clin Neurosci 258 (2008) 300-304
13. Czerski P.M., Rybakowski F., Kapelski P., Rybakowski J.K., Dmitrzak-Weglarz M., Leszczynska-Rodziewicz A., et al. Association of tumor necrosis factor - 308G/A promoter polymorphism with schizophrenia and bipolar affective disorder in a Polish population. Neuropsychobiology 57 (2008) 88-94
14. Dentice M., Bandyopadhyay A., Gereben B., Callebaut I., Christoffolete M.A., Kim B.W., et al. The Hedgehog-inducible ubiquitin ligase subunit WSB-1 modulates thyroid hormone activation and PTHrP secretion in the developing growth plate. Nat Cell Biol 7 (2005) 698-705
15. Detera-Wadleigh S.D., Badner J.A., Berrettini W.H., Yoshikawa T., Goldin L.R., Turner G., et al. A high-density genome scan detects evidence for a bipolar-disorder susceptibility locus on 13q32 and other potential loci on 1q32 and 18p11.2. Proc Natl Acad Sci U S A 96 (1999) 5604-5609
16. Ekholm J.M., Pekkarinen P., Pajukanta P., Kieseppa T., Partonen T., Paunio T., et al. Bipolar disorder susceptibility region on Xq24-q27.1 in Finnish families. Mol Psychiatry 7 (2002) 453-459
17. Faul F., Erdfelder E., Lang A.G., and Buchner A. G*Power 3: a flexible statistical power analysis program for the social, behavioral, and biomedical sciences. Behav Res Methods 39 (2007) 175-191
18. Frye M.A., Denicoff K.D., Bryan A.L., Smith-Jackson E.E., Ali S.O., Luckenbaugh D., et al. Association between lower serum free T4 and greater mood instability and depression in lithium-maintained bipolar patients. Am J Psychiatry 156 (1999) 1909-1914
19. Gereben B., Kollar A., Harney J.W., and Larsen P.R. The mRNA structure has potent regulatory effects on type 2 iodothyronine deiodinase expression. Mol Endocrinol 16 (2002) 1667-1679
20. Greenwood T.A., Alexander M., Keck P.E., McElroy S., Sadovnick A.D., Remick R.A., et al. Evidence for linkage disequilibrium between the dopamine transporter and bipolar disorder. Am J Med Genet 105 (2001) 145-151
21. Guo T.W., Zhang F.C., Yang M.S., Gao X.C., Bian L., Duan S.W., et al. Positive association of the DIO2 (deiodinase type 2) gene with mental retardation in the iodine-deficient areas of China. J Med Genet 41 (2004) 585-590
22. Hatterer J.A., Kocsis J.H., and Stokes P.E. Thyroid function in patients maintained on lithium. Psychiatry Res 26 (1988) 249-257
23. Kendler K.S., Pedersen N., Johnson L., Neale M.C., and Mathe A.A. A pilot Swedish twin study of affective illness, including hospital- and population-ascertained subsamples. Arch Gen Psychiatry 50 (1993) 699-700
24. Kessler R.C., Chiu W.T., Demler O., Merikangas K.R., and Walters E.E. Prevalence, severity, and comorbidity of 12-month DSM-IV disorders in the National Comorbidity Survey Replication. Arch Gen Psychiatry 62 (2005) 617-627
25. Kirkegaard C., and Faber J. The role of thyroid hormones in depression. Eur J Endocrinol 138 (1998) 1-9
26. Lachman H.M., Morrow B., Shprintzen R., Veit S., Parsia S.S., Faedda G., et al. Association of codon 108/158 catechol-O-methyltransferase gene polymorphism with the psychiatric manifestations of velo-cardio-facial syndrome. Am J Med Genet 67 (1996) 468-472
27. Liu J., Juo S.H., Dewan A., Grunn A., Tong X., Brito M., et al. Evidence for a putative bipolar disorder locus on 2p13-16 and other potential loci on 4q31, 7q34, 8q13, 9q31, 10q21-24, 13q32, 14q21 and 17q11-12. Mol Psychiatry 8 (2003) 333-342
28. Mendlewicz J., and Rainer J.D. Adoption study supporting genetic transmission in manic-depressive illness. Nature 268 (1977) 327-329
29. Meulenbelt I., Min J.L., Bos S., Riyazi N., Houwing-Duistermaat J.J., van der Wijk H.J., et al. Identification of DIO2 as a new susceptibility locus for symptomatic osteoarthritis. Hum Mol Genet 17 (2008) 1867-1875
30. Oomen H.A., Schipperijn A.J., and Drexhage H.A. The prevalence of affective disorder and in particular of a rapid cycling of bipolar disorder in patients with abnormal thyroid function tests. Clin Endocrinol (Oxf) 45 (1996) 215-223
31. Ortiz-Dominguez A., Hernandez M.E., Berlanga C., Gutierrez-Mora D., Moreno J., Heinze G., et al. Immune variations in bipolar disorder: phasic differences. Bipolar Disord 9 (2007) 596-602
32. Pearce J.M. Myxoedema and Sir William Withey Gull (1816-1890). J Neurol Neurosurg Psychiatry 77 (2006) 639
33. Peeters R.P., van den Beld A.W., Attalki H., Toor H., de Rijke Y.B., Kuiper G.G., et al. A new polymorphism in the type II deiodinase gene is associated with circulating thyroid hormone parameters. Am J Physiol Endocrinol Metab 289 (2005) E75-81
34. Pekkarinen P., Terwilliger J., Bredbacka P.E., Lonnqvist J., and Peltonen L. Evidence of a predisposing locus to bipolar disorder on Xq24-q27.1 in an extended Finnish pedigree. Genome Res 5 (1995) 105-115
35. Potash J.B., Zandi P.P., Willour V.L., Lan T.H., Huo Y., Avramopoulos D., et al. Suggestive linkage to chromosomal regions 13q31 and 22q12 in families with psychotic bipolar disorder. Am J Psychiatry 160 (2003) 680-686
36. Preisig M., Bellivier F., Fenton B.T., Baud P., Berney A., Courtet P., et al. Association between bipolar disorder and monoamine oxidase A gene polymorphisms: results of a multicenter study. Am J Psychiatry 157 (2000) 948-955
37. Rotondo A., Mazzanti C., Dell'Osso L., Rucci P., Sullivan P., Bouanani S., et al. Catechol o-methyltransferase, serotonin transporter, and tryptophan hydroxylase gene polymorphisms in bipolar disorder patients with and without comorbid panic disorder. Am J Psychiatry 159 (2002) 23-29
38. Schatzberg A.F., and Lindley S. Glucocorticoid antagonists in neuropsychiatric [corrected] disorders. Eur J Pharmacol 583 (2008) 358-364
39. Shao L., and Vawter M.P. Shared gene expression alterations in schizophrenia and bipolar disorder. Biol Psychiatry 64 (2008) 89-97
40. Shi Y.Y., and He L. SHEsis, a powerful software platform for analyses of linkage disequilibrium, haplotype construction, and genetic association at polymorphism loci. Cell Res 15 (2005) 97-98
41. Sklar P., Gabriel S.B., McInnis M.G., Bennett P., Lim Y.M., Tsan G., et al. Family-based association study of 76 candidate genes in bipolar disorder: BDNF is a potential risk locus. Brain-derived neutrophic factor. Mol Psychiatry 7 (2002) 579-593
42. Stine O.C., McMahon F.J., Chen L., Xu J., Meyers D.A., MacKinnon D.F., et al. Initial genome screen for bipolar disorder in the NIMH genetics initiative pedigrees: chromosomes 2, 11, 13, 14, and X. Am J Med Genet 74 (1997) 263-269
43. Thomsen A.F., Kvist T.K., Andersen P.K., and Kessing L.V. Increased risk of developing affective disorder in patients with hypothyroidism: a register-based study. Thyroid 15 (2005) 700-707
44. Torlontano M., Durante C., Torrente I., Crocetti U., Augello G., Ronga G., et al. Type 2 deiodinase polymorphism (threonine 92 alanine) predicts L-thyroxine dose to achieve target thyrotropin levels in thyroidectomized patients. J Clin Endocrinol Metab 93 (2008) 910-913
45. Turianitsa I.M., Lavkai I., Mishanich I.I., Margitich V.M., and Razhov K.F. [Status of the thyroid gland in patients with schizophrenia]. Zh Nevropatol Psikhiatr Im S S Korsakova 91 (1991) 122-123
46. Valle J., Ayuso-Gutierrez J.L., Abril A., and Ayuso-Mateos J.L. Evaluation of thyroid function in lithium-naive bipolar patients. Eur Psychiatry 14 (1999) 341-345
47. Willour V.L., Chen H., Toolan J., Belmonte P., Cutler D.J., Goes F.S., et al. Family-based association of FKBP5 in bipolar disorder. Mol Psychiatry (2008)
48. Zandi P.P., Willour V.L., Huo Y., Chellis J., Potash J.B., MacKinnon D.F., et al. Genome scan of a second wave of NIMH genetics initiative bipolar pedigrees: chromosomes 2, 11, 13, 14, and X. Am J Med Genet B Neuropsychiatr Genet 119B (2003) 69-76